| 5/17/2024 | Artal Group S.A. | 455,081 | $20.49M | 0.5% | N/A | 0.775% | |
| 5/16/2024 | California State Teachers Retirement System | 33,745 | $1.52M | 0.0% | +2.9% | 0.057% | |
| 5/16/2024 | Janus Henderson Group PLC | 542,580 | $24.43M | 0.0% | +2.2% | 0.924% | |
| 5/16/2024 | BVF Inc. IL | 1,172,249 | $52.79M | 1.5% | -57.4% | 1.997% | |
| 5/15/2024 | Bellevue Group AG | 9,800 | $441K | 0.0% | -56.8% | 0.017% | |
| 5/15/2024 | Price T Rowe Associates Inc. MD | 1,185,354 | $53.38M | 0.0% | N/A | 2.020% | |
|
| 5/15/2024 | Altitude Crest Partners Inc. | 109,837 | $4.95M | 2.1% | N/A | 0.187% | |
| 5/14/2024 | Nan Fung Group Holdings Ltd | 89,516 | $4.03M | 3.7% | -34.7% | 0.153% | |
| 5/14/2024 | Decheng Capital LLC | 101,798 | $4.58M | 0.6% | N/A | 0.173% | |
| 5/14/2024 | Platinum Investment Management Ltd. | 99,490 | $4.48M | 0.2% | -30.0% | 0.170% | |
| 5/14/2024 | Healthcare of Ontario Pension Plan Trust Fund | 52,000 | $2.34M | 0.0% | N/A | 0.089% | |
| 5/10/2024 | Vanguard Group Inc. | 156,149 | $7.03M | 0.0% | +2.8% | 0.266% | |
| 5/9/2024 | Mitsubishi UFJ Asset Management Co. Ltd. | 9,671 | $435K | 0.0% | -4.4% | 0.016% | |
| 5/7/2024 | Susquehanna Fundamental Investments LLC | 39,910 | $1.80M | 0.1% | N/A | 0.068% | |
| 5/7/2024 | Susquehanna Portfolio Strategies LLC | 18,934 | $853K | 0.0% | -23.1% | 0.032% | |
| 5/7/2024 | Swiss National Bank | 74,054 | $3.34M | 0.0% | +1.9% | 0.126% | |
| 5/7/2024 | SG Americas Securities LLC | 2,409 | $108K | 0.0% | N/A | 0.004% | |
| 5/6/2024 | Quantbot Technologies LP | 7,300 | $329K | 0.0% | +160.7% | 0.012% | |
| 5/1/2024 | BNP Paribas Financial Markets | 102,885 | $4.63M | 0.0% | +63.8% | 0.175% | |
| 4/30/2024 | Allspring Global Investments Holdings LLC | 1,590 | $72K | 0.0% | N/A | 0.003% | |
| 4/29/2024 | China Universal Asset Management Co. Ltd. | 11,113 | $500K | 0.1% | +66.3% | 0.019% | |
| 4/18/2024 | Allspring Global Investments Holdings LLC | 1,590 | $72K | 0.0% | N/A | 0.003% | |
| 4/15/2024 | Medicxi Ventures Management Jersey Ltd | 1,169,028 | $52.64M | 11.7% | -26.9% | 1.992% | |
| 3/5/2024 | Wellington Management Group LLP | 2,009,403 | $55.26M | 0.0% | -26.5% | 3.472% | |
| 2/22/2024 | Sierra Summit Advisors LLC | 8,049 | $221K | 0.1% | N/A | 0.014% | |
| 2/15/2024 | Parkman Healthcare Partners LLC | 157,817 | $4.34M | 0.6% | +20.7% | 0.273% | |
| 2/15/2024 | Great Point Partners LLC | 20,000 | $550K | 0.1% | N/A | 0.035% | |
| 2/14/2024 | ADAR1 Capital Management LLC | 24,000 | $660K | 0.2% | N/A | 0.042% | |
| 2/14/2024 | Commodore Capital LP | 4,747,373 | $130.55M | 11.6% | +7.2% | 8.223% | |
| 2/14/2024 | Braidwell LP | 370,679 | $10.19M | 0.4% | -80.5% | 0.642% | |
| 2/14/2024 | Bellevue Group AG | 22,700 | $624K | 0.0% | -49.0% | 0.039% | |
| 2/14/2024 | Avoro Capital Advisors LLC | 888,888 | $24.44M | 0.3% | +100.0% | 1.540% | |
| 2/14/2024 | RTW Investments LP | 2,373,625 | $65.28M | 1.0% | +18.9% | 4.112% | |
| 2/13/2024 | Tower Research Capital LLC TRC | 2,120 | $58K | 0.0% | +64.1% | 0.004% | |
| 2/13/2024 | Carmignac Gestion | 403,861 | $11.13M | 0.2% | -11.1% | 0.700% | |
| 2/13/2024 | Campbell & CO Investment Adviser LLC | 48,007 | $1.32M | 0.1% | N/A | 0.083% | |
| 2/9/2024 | Franklin Resources Inc. | 1,883,091 | $51.79M | 0.0% | -0.5% | 3.262% | |
| 2/9/2024 | Trexquant Investment LP | 40,489 | $1.11M | 0.0% | +138.4% | 0.070% | |
| 2/8/2024 | Quadrant Capital Group LLC | 1,253 | $34K | 0.0% | +37.7% | 0.002% | |
| 2/8/2024 | Mitsubishi UFJ Asset Management Co. Ltd. | 10,114 | $283K | 0.0% | -24.8% | 0.018% | |
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| 2/7/2024 | Jump Financial LLC | 46,120 | $1.27M | 0.0% | N/A | 0.080% | |
| 2/7/2024 | BNP Paribas Financial Markets | 62,825 | $1.73M | 0.0% | +135.6% | 0.109% | |
| 2/7/2024 | Teacher Retirement System of Texas | 8,787 | $242K | 0.0% | -27.3% | 0.015% | |
| 2/6/2024 | Swiss National Bank | 72,654 | $2.00M | 0.0% | -22.2% | 0.126% | |
| 2/5/2024 | Victory Capital Management Inc. | 10,770 | $296K | 0.0% | N/A | 0.019% | |
| 2/5/2024 | Russell Investments Group Ltd. | 1,341 | $37K | 0.0% | -47.8% | 0.002% | |
| 2/1/2024 | New York State Common Retirement Fund | 2,428 | $67K | 0.0% | -45.7% | 0.004% | |
| 1/31/2024 | Federated Hermes Inc. | 3,637,309 | $100.03M | 0.2% | +26.0% | 6.301% | |
| 1/30/2024 | HealthInvest Partners AB | 24,325 | $669K | 0.5% | N/A | 0.042% | |
| 1/24/2024 | DekaBank Deutsche Girozentrale | 56,000 | $1.55M | 0.0% | +124.0% | 0.097% | |
| 1/24/2024 | Arizona State Retirement System | 10,299 | $283K | 0.0% | -14.9% | 0.018% | |
| 1/24/2024 | China Universal Asset Management Co. Ltd. | 6,681 | $184K | 0.0% | +352.3% | 0.012% | |
| 1/5/2024 | Exchange Traded Concepts LLC | 5,753 | $158K | 0.0% | +34.0% | 0.010% | |
| 12/7/2023 | Hudson Bay Capital Management LP | 167,818 | $3.96M | 0.0% | +106.4% | 0.291% | |
| 12/1/2023 | Wellington Management Group LLP | 2,735,247 | $64.50M | 0.0% | +2.2% | 4.738% | |
| 11/29/2023 | Carmignac Gestion | 454,331 | $10.76M | 0.2% | +9.7% | 0.787% | |
| 11/22/2023 | Polar Capital Holdings Plc | 500,000 | $11.79M | 0.1% | -33.3% | 0.866% | |
| 11/15/2023 | RTW Investments LP | 1,996,764 | $47.08M | 1.0% | +90.0% | 3.459% | |
| 11/15/2023 | Rock Springs Capital Management LP | 838,428 | $19.77M | 0.5% | +75.2% | 1.452% | |
| 11/15/2023 | Adage Capital Partners GP L.L.C. | 100,000 | $2.36M | 0.0% | N/A | 0.173% | |
| 11/14/2023 | Braidwell LP | 1,901,337 | $44.83M | 1.4% | +23.2% | 3.293% | |
| 11/14/2023 | Schonfeld Strategic Advisors LLC | 239,370 | $5.64M | 0.0% | +47.3% | 0.415% | |
| 11/14/2023 | Corton Capital Inc. | 12,420 | $293K | 0.1% | +33.6% | 0.022% | |
| 11/14/2023 | Deerfield Management Company L.P. Series C | 3,876,938 | $91.42M | 2.0% | +27.9% | 6.716% | |
| 11/14/2023 | Lynx1 Capital Management LP | 1,150,225 | $27.12M | 17.9% | -0.2% | 1.992% | |
| 11/14/2023 | Trexquant Investment LP | 16,986 | $401K | 0.0% | N/A | 0.029% | |
| 11/14/2023 | Monashee Investment Management LLC | 45,000 | $1.06M | 0.4% | N/A | 0.078% | |
| 11/14/2023 | Nan Fung Group Holdings Ltd | 137,038 | $3.23M | 2.6% | -9.2% | 0.237% | |
| 11/13/2023 | Algert Global LLC | 70,482 | $1.66M | 0.1% | -29.3% | 0.122% | |
| 11/13/2023 | Federated Hermes Inc. | 2,885,700 | $68.05M | 0.2% | +9.4% | 4.999% | |
| 11/13/2023 | Silverarc Capital Management LLC | 500,000 | $11.79M | 3.6% | -15.1% | 0.866% | |
| 11/13/2023 | FMR LLC | 774,953 | $18.27M | 0.0% | +30.3% | 1.342% | |
| 11/8/2023 | Swiss National Bank | 93,354 | $2.20M | 0.0% | +43.7% | 0.187% | |
| 11/7/2023 | Alpha DNA Investment Management LLC | 25,380 | $598K | 0.2% | -11.9% | 0.051% | |
| 11/7/2023 | Barclays PLC | 47,790 | $1.13M | 0.0% | -56.6% | 0.096% | |
| 11/7/2023 | Arizona State Retirement System | 12,103 | $285K | 0.0% | +43.1% | 0.024% | |
| 11/7/2023 | Mitsubishi UFJ Kokusai Asset Management Co. Ltd. | 13,446 | $317K | 0.0% | +10.8% | 0.027% | |
| 11/3/2023 | Platinum Investment Management Ltd. | 142,029 | $3.35M | 0.1% | -5.5% | 0.285% | |
| 10/31/2023 | Teacher Retirement System of Texas | 12,084 | $285K | 0.0% | +47.9% | 0.024% | |
| 10/31/2023 | China Universal Asset Management Co. Ltd. | 1,477 | $35K | 0.0% | +142.1% | 0.003% | |
| 10/25/2023 | BluePath Capital Management LLC | 1,383 | $33K | 0.0% | N/A | 0.003% | |
| 10/18/2023 | Exchange Traded Concepts LLC | 4,294 | $101K | 0.0% | -20.8% | 0.009% | |
| 10/17/2023 | Mach 1 Financial Group LLC | 22,435 | $529K | 0.2% | +13.9% | 0.045% | |
| 10/11/2023 | AE Wealth Management LLC | 22,500 | $531K | 0.0% | +14.2% | 0.045% | |
| 8/15/2023 | Silverarc Capital Management LLC | 589,255 | $15.52M | 4.8% | -11.9% | 1.182% | |
| 8/15/2023 | Sphera Funds Management LTD. | 278,333 | $7.33M | 1.1% | -17.4% | 0.558% | |
| 8/15/2023 | HighVista Strategies LLC | 34,027 | $896K | 0.4% | -26.0% | 0.068% | |
| 8/15/2023 | Braidwell LP | 1,543,162 | $40.63M | 1.3% | +4.8% | 3.095% | |
| 8/15/2023 | BVF Inc. IL | 1,602,420 | $42.19M | 1.2% | -46.2% | 3.214% | |
| 8/15/2023 | Commodore Capital LP | 4,000,000 | $105.32M | 11.8% | +35.6% | 8.022% | |
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| 8/14/2023 | Bellevue Group AG | 44,500 | $1.17M | 0.0% | -2.6% | 0.089% | |
| 8/14/2023 | Rock Springs Capital Management LP | 478,531 | $12.60M | 0.3% | N/A | 0.960% | |
| 8/14/2023 | Driehaus Capital Management LLC | 1,136,716 | $29.93M | 0.4% | +2.9% | 2.280% | |
| 8/11/2023 | VR Adviser LLC | 1,726,214 | $45.45M | 7.3% | +40.8% | 3.462% | |
| 8/11/2023 | Franklin Resources Inc. | 1,592,258 | $41.92M | 0.0% | +0.1% | 3.193% | |
| 8/11/2023 | Platinum Investment Management Ltd. | 150,238 | $3.96M | 0.1% | -37.2% | 0.301% | |
| 8/9/2023 | BNP Paribas Arbitrage SNC | 28,118 | $740K | 0.0% | +3,725.6% | 0.060% | |
| 8/9/2023 | Mitsubishi UFJ Kokusai Asset Management Co. Ltd. | 12,136 | $320K | 0.0% | -26.5% | 0.026% | |
| 8/3/2023 | Barclays PLC | 110,159 | $2.90M | 0.0% | N/A | 0.221% | |
| 8/3/2023 | Innovis Asset Management LLC | 13,299 | $350K | 0.1% | N/A | 0.029% | |
