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Avoro Capital Advisors LLC Top Holdings and 13F Report (2024)

About Avoro Capital Advisors LLC

Investment Activity

  • Avoro Capital Advisors LLC has $6.86 billion in total holdings as of September 30, 2024.
  • Avoro Capital Advisors LLC owns shares of 36 different stocks, but just 14 companies or ETFs make up 80% of its holdings.
  • Approximately 4.39% of the portfolio was purchased this quarter.
  • About 16.45% of the portfolio was sold this quarter.
  • This quarter, Avoro Capital Advisors LLC has purchased 41 new stocks and bought additional shares in 10 stocks.
  • Avoro Capital Advisors LLC sold shares of 8 stocks and completely divested from 6 stocks this quarter.

Largest Holdings

United Therapeutics
$1,024,482,515
Ascendis Pharma A/S
$744,890,867
argenx
$671,348,191
Krystal Biotech
$477,323,071

Largest New Holdings this Quarter

INSMED INC
$125,000 Holding

Largest Purchases this Quarter

Ascendis Pharma A/S
792,227 shares (about $118.29M)
Vaxcyte
600,000 shares (about $68.56M)
Krystal Biotech
189,222 shares (about $34.44M)
Kymera Therapeutics
611,112 shares (about $28.92M)
DYNE THERAPEUTICS INC.
534,249 shares (about $19.19M)

Largest Sales this Quarter

BioMarin Pharmaceutical
2,519,401 shares (about $177.09M)
Iovance Biotherapeutics
7,460,000 shares (about $70.05M)
Sarepta Therapeutics
444,445 shares (about $55.51M)
Amicus Therapeutics
4,225,000 shares (about $45.12M)
SPYRE THERAPEUTICS INC
1,240,538 shares (about $36.48M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofAvoro Capital Advisors LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
United Therapeutics Co. stock logo
UTHR
United Therapeutics
$1,024,482,5150.0%2,858,88814.9%Medical
Ascendis Pharma A/S stock logo
ASND
Ascendis Pharma A/S
$744,890,867$118,287,413 18.9%4,988,88810.9%Medical
argenx SE stock logo
ARGX
argenx
$671,348,1910.0%1,238,4679.8%Medical
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
$477,323,071$34,444,081 7.8%2,622,2227.0%Medical
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
$430,594,380$5,635,502 -1.3%2,029,0006.3%Medical
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
$320,444,4410.0%11,111,1114.7%Medical
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$319,163,264$55,506,736 -14.8%2,555,5554.7%Medical
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
$315,768,750$16,994,100 5.7%6,875,0004.6%Medical
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
$247,509,000$45,123,000 -15.4%23,175,0003.6%Medical
Intra-Cellular Therapies, Inc. stock logo
ITCI
Intra-Cellular Therapies
$223,168,500$3,658,500 1.7%3,050,0003.3%Medical
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
$223,096,6400.0%5,666,6663.3%Medical
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
$212,985,000$28,923,931 15.7%4,500,0003.1%Medical
Vera Therapeutics, Inc. stock logo
VERA
Vera Therapeutics
$190,483,8780.0%4,309,5902.8%Medical
Arrowhead Pharmaceuticals, Inc. stock logo
ARWR
Arrowhead Pharmaceuticals
$172,177,7610.0%8,888,8882.5%Medical
BioMarin Pharmaceutical Inc. stock logo
BMRN
BioMarin Pharmaceutical
$143,252,074$177,088,696 -55.3%2,038,0152.1%Medical
MoonLake Immunotherapeutics stock logo
MLTX
MoonLake Immunotherapeutics
$139,668,442$5,042 0.0%2,770,1002.0%Medical
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$134,267,250$68,562,000 104.3%1,175,0002.0%Medical
Soleno Therapeutics, Inc. stock logo
SLNO
Soleno Therapeutics
$110,118,690$4,510,474 4.3%2,181,0001.6%Medical
BioCryst Pharmaceuticals, Inc. stock logo
BCRX
BioCryst Pharmaceuticals
$90,174,000$5,358,000 -5.6%11,865,0001.3%Medical
Syndax Pharmaceuticals, Inc. stock logo
SNDX
Syndax Pharmaceuticals
$74,852,4120.0%3,888,4371.1%Medical
Ocular Therapeutix, Inc. stock logo
OCUL
Ocular Therapeutix
$70,122,0000.0%8,060,0001.0%Medical
Kura Oncology, Inc. stock logo
KURA
Kura Oncology
$69,201,0080.0%3,541,5051.0%Medical
Merus stock logo
MRUS
Merus
$67,695,8000.0%1,355,0001.0%Medical
TOURMALINE BIO INC
$57,133,3280.0%2,222,2220.8%Common
MannKind Co. stock logo
MNKD
MannKind
$55,037,500$59,906 -0.1%8,750,0000.8%Medical
Ultragenyx Pharmaceutical Inc. stock logo
RARE
Ultragenyx Pharmaceutical
$46,106,5000.0%830,0000.7%Medical
Autolus Therapeutics plc stock logo
AUTL
Autolus Therapeutics
$44,814,8110.0%12,345,6780.7%Medical
Iovance Biotherapeutics, Inc. stock logo
IOVA
Iovance Biotherapeutics
$39,813,600$70,049,400 -63.8%4,240,0000.6%Medical
Taysha Gene Therapies, Inc. stock logo
TSHA
Taysha Gene Therapies
$37,486,5000.0%18,650,0000.5%Medical
Monte Rosa Therapeutics, Inc. stock logo
GLUE
Monte Rosa Therapeutics
$30,688,251$6,652,751 27.7%5,790,2360.4%Medical
CG ONCOLOGY INC
$26,411,0000.0%700,0000.4%Common
DYNE THERAPEUTICS INC.
$23,348,000$19,190,224 461.6%650,0000.3%Common
SPYRE THERAPEUTICS INC
$17,604,826$36,484,223 -67.5%598,6000.3%Common
Aadi Bioscience, Inc. stock logo
AADI
Aadi Bioscience
$5,869,7680.0%2,849,4020.1%Medical
NEUROGENE INC
$924,3370.0%22,0290.0%Common
INSMED INC
$125,000$125,000 New Holding50,0000.0%Common
Cerevel Therapeutics Holdings, Inc. stock logo
CERE
Cerevel Therapeutics
$0$308,292,077 -100.0%00.0%Medical
SPDR S&P Biotech ETF stock logo
XBI
SPDR S&P Biotech ETF
$0$281,374,850 -100.0%00.0%ETF
Alnylam Pharmaceuticals, Inc. stock logo
ALNY
Alnylam Pharmaceuticals
$0$97,200,000 -100.0%00.0%Medical
Verrica Pharmaceuticals Inc. stock logo
VRCA
Verrica Pharmaceuticals
$0$29,159,993 -100.0%00.0%Medical
Bicycle Therapeutics plc stock logo
BCYC
Bicycle Therapeutics
$0$14,168,000 -100.0%00.0%Medical
ADVERUM BIOTECHNOLOGIES INC
$0$2,858,329 -100.0%00.0%Common

Showing largest 100 holdings. View all holdings.
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