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Casdin Capital, LLC Top Holdings and 13F Report (2021)

About Casdin Capital, LLC

Investment Activity

  • Casdin Capital, LLC has $1.50 billion in total holdings as of September 30, 2021.
  • Casdin Capital, LLC owns shares of 38 different stocks, but just 11 companies or ETFs make up 80% of its holdings.
  • Approximately 4.86% of the portfolio was purchased this quarter.
  • About 3.26% of the portfolio was sold this quarter.
  • This quarter, Casdin Capital, LLC has purchased 35 new stocks and bought additional shares in 3 stocks.
  • Casdin Capital, LLC sold shares of 5 stocks and completely divested from 2 stocks this quarter.

Largest Holdings

GeneDx
$269,560,625
BioLife Solutions
$226,038,003
Standard BioTools
$124,695,685

Largest New Holdings this Quarter

Moderna
$14,553,000 Holding
SEPTERNA INC
$12,669,837 Holding
Agios Pharmaceuticals
$8,215,000 Holding
Fortrea
$5,128,750 Holding
Recursion Pharmaceuticals
$1,117,583 Holding

Largest Purchases this Quarter

NEUROGENE INC
770,745 shares (about $17.62M)
Moderna
350,000 shares (about $14.55M)
SEPTERNA INC
553,268 shares (about $12.67M)
Beam Therapeutics
475,000 shares (about $11.78M)
Agios Pharmaceuticals
250,000 shares (about $8.22M)

Largest Sales this Quarter

Revolution Medicines
415,000 shares (about $18.15M)
Veracyte
390,000 shares (about $15.44M)
Alnylam Pharmaceuticals
30,000 shares (about $7.06M)
Relay Therapeutics
302,534 shares (about $1.25M)
Avidity Biosciences
39,841 shares (about $1.16M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofCasdin Capital, LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
GeneDx Holdings Corp. stock logo
WGS
GeneDx
$269,560,6250.0%3,507,16417.9%Medical
BioLife Solutions, Inc. stock logo
BLFS
BioLife Solutions
$226,038,0030.0%8,707,16515.0%Medical
Revolution Medicines, Inc. stock logo
RVMD
Revolution Medicines
$161,806,638$18,152,100 -10.1%3,699,28310.8%Medical
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$130,526,8650.0%1,073,5008.7%Medical
Standard BioTools Inc. stock logo
LAB
Standard BioTools
$124,695,6850.0%71,254,6778.3%Medical
Illumina, Inc. stock logo
ILMN
Illumina
$100,222,5000.0%750,0006.7%Medical
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
$59,468,600$1,158,576 -1.9%2,045,0004.0%Medical
Codexis, Inc. stock logo
CDXS
Codexis
$38,637,0000.0%8,100,0002.6%Medical
Relay Therapeutics, Inc. stock logo
RLAY
Relay Therapeutics
$36,868,125$1,246,440 -3.3%8,948,5742.5%Medical
Exact Sciences Co. stock logo
EXAS
Exact Sciences
$36,523,5000.0%650,0002.4%Medical
Alnylam Pharmaceuticals, Inc. stock logo
ALNY
Alnylam Pharmaceuticals
$32,943,400$7,059,300 -17.6%140,0002.2%Medical
Beam Therapeutics Inc. stock logo
BEAM
Beam Therapeutics
$31,000,000$11,780,000 61.3%1,250,0002.1%Medical
NEUROGENE INC
$29,611,952$17,619,230 146.9%1,295,3612.0%COM
Blueprint Medicines Co. stock logo
BPMC
Blueprint Medicines
$28,466,6890.0%326,3781.9%Medical
Intellia Therapeutics, Inc. stock logo
NTLA
Intellia Therapeutics
$23,320,0000.0%2,000,0001.6%Medical
Verve Therapeutics, Inc. stock logo
VERV
Verve Therapeutics
$22,535,0200.0%3,995,5711.5%Medical
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
$20,176,2000.0%990,0001.3%Medical
Structure Therapeutics Inc. stock logo
GPCR
Structure Therapeutics
$18,984,0000.0%700,0001.3%Medical
Moderna, Inc. stock logo
MRNA
Moderna
$14,553,000$14,553,000 New Holding350,0001.0%Medical
SEPTERNA INC
$12,669,837$12,669,837 New Holding553,2680.8%COM
Veracyte, Inc. stock logo
VCYT
Veracyte
$10,941,797$15,444,000 -58.5%276,3080.7%Medical
Guardant Health, Inc. stock logo
GH
Guardant Health
$10,692,5000.0%350,0000.7%Medical
Tenaya Therapeutics, Inc. stock logo
TNYA
Tenaya Therapeutics
$9,628,1490.0%6,732,9710.6%Medical
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
$8,215,000$8,215,000 New Holding250,0000.5%Medical
4D Molecular Therapeutics, Inc. stock logo
FDMT
4D Molecular Therapeutics
$6,405,5000.0%1,150,0000.4%Medical
Syndax Pharmaceuticals, Inc. stock logo
SNDX
Syndax Pharmaceuticals
$6,279,5000.0%475,0000.4%Medical
2seventy bio, Inc. stock logo
TSVT
2seventy bio
$5,880,0000.0%2,000,0000.4%Medical
Century Therapeutics, Inc. stock logo
IPSC
Century Therapeutics
$5,242,411$1,997,972 61.6%5,190,5060.3%Medical
Fortrea Holdings Inc. stock logo
FTRE
Fortrea
$5,128,750$5,128,750 New Holding275,0000.3%Medical
CONTINEUM THERAPEUTICS INC
$4,346,1570.0%296,6660.3%CL A
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
$3,671,9980.0%1,188,3490.2%Medical
Absci Co. stock logo
ABSI
Absci
$2,549,9410.0%973,2600.2%Medical
Pacific Biosciences of California, Inc. stock logo
PACB
Pacific Biosciences of California
$1,895,6220.0%1,035,8590.1%Medical
Recursion Pharmaceuticals, Inc. stock logo
RXRX
Recursion Pharmaceuticals
$1,117,583$1,117,583 New Holding165,3230.1%Medical
Prime Medicine, Inc. stock logo
PRME
Prime Medicine
$1,072,1510.0%367,1750.1%Medical
Monte Rosa Therapeutics, Inc. stock logo
GLUE
Monte Rosa Therapeutics
$596,9370.0%86,0140.0%Medical
GINKGO BIOWORKS HOLDINGS INC
$358,3610.0%36,4930.0%CL A NEW
Kronos Bio, Inc. stock logo
KRON
Kronos Bio
$117,6470.0%123,8390.0%Medical
GRAIL INC
$0$4,816,000 -100.0%00.0%COM
Exscientia plc stock logo
EXAI
Exscientia
$0$1,043,832 -100.0%00.0%Medical

Showing largest 100 holdings. View all holdings.
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