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Checkpoint Capital L.P. Top Holdings and 13F Report (2025)

About Checkpoint Capital L.P.

Investment Activity

  • Checkpoint Capital L.P. has $196.48 million in total holdings as of December 31, 2024.
  • Checkpoint Capital L.P. owns shares of 16 different stocks, but just 7 companies or ETFs make up 80% of its holdings.
  • Approximately 21.96% of the portfolio was purchased this quarter.
  • About 20.82% of the portfolio was sold this quarter.
  • This quarter, Checkpoint Capital L.P. has purchased 16 new stocks and bought additional shares in 9 stocks.
  • Checkpoint Capital L.P. sold shares of 4 stocks and completely divested from 2 stocks this quarter.

Largest Holdings

argenx
$56,887,500
Disc Medicine
$11,729,000

Largest New Holdings this Quarter

Revolution Medicines
$9,185,400 Holding
Kymera Therapeutics
$3,119,233 Holding

Largest Purchases this Quarter

Disc Medicine
159,457 shares (about $10.11M)
Revolution Medicines
210,000 shares (about $9.19M)
Phathom Pharmaceuticals
769,850 shares (about $6.25M)
Rhythm Pharmaceuticals
64,601 shares (about $3.62M)
Trevi Therapeutics
834,135 shares (about $3.44M)

Largest Sales this Quarter

Cytokinetics
446,813 shares (about $21.02M)
aTyr Pharma
1,303,916 shares (about $4.72M)
Axsome Therapeutics
34,863 shares (about $2.95M)
AVADEL PHARMACEUTICALS PLC
95,210 shares (about $1.00M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofCheckpoint Capital L.P.

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
argenx SE stock logo
ARGX
argenx
$56,887,5000.0%92,50029.0%Medical
Rhythm Pharmaceuticals, Inc. stock logo
RYTM
Rhythm Pharmaceuticals
$40,752,432$3,616,364 9.7%727,98220.7%Medical
Phathom Pharmaceuticals, Inc. stock logo
PHAT
Phathom Pharmaceuticals
$18,466,155$6,251,182 51.2%2,274,1579.4%Medical
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
$14,787,205$2,949,758 -16.6%174,7697.5%Medical
Disc Medicine, Inc. stock logo
IRON
Disc Medicine
$11,729,000$10,109,574 624.3%185,0006.0%Medical
AVADEL PHARMACEUTICALS PLC
$10,560,343$1,000,657 -8.7%1,004,7905.4%COM SHS
Revolution Medicines, Inc. stock logo
RVMD
Revolution Medicines
$9,185,400$9,185,400 New Holding210,0004.7%Medical
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
$7,052,456$2,047,856 40.9%535,4943.6%Medical
TScan Therapeutics, Inc. stock logo
TCRX
TScan Therapeutics
$5,338,200$2,829,164 112.8%1,755,9872.7%Medical
CIDARA THERAPEUTICS INC
$5,113,728$377,086 8.0%196,9492.6%COM NEW
Trevi Therapeutics, Inc. stock logo
TRVI
Trevi Therapeutics
$4,466,636$3,436,636 333.7%1,084,1352.3%Medical
Stoke Therapeutics, Inc. stock logo
STOK
Stoke Therapeutics
$3,368,419$1,631,039 93.9%305,3871.7%Medical
Soleno Therapeutics, Inc. stock logo
SLNO
Soleno Therapeutics
$3,147,714$541,378 20.8%70,0271.6%Medical
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
$3,119,233$3,119,233 New Holding77,5351.6%Medical
aTyr Pharma, Inc. stock logo
LIFE
aTyr Pharma
$1,565,871$4,720,176 -75.1%432,5610.8%Medical
Cytokinetics, Incorporated stock logo
CYTK
Cytokinetics
$940,800$21,018,084 -95.7%20,0000.5%Medical
Protagonist Therapeutics, Inc. stock logo
PTGX
Protagonist Therapeutics
$0$10,800,000 -100.0%00.0%Medical
Allakos Inc. stock logo
ALLK
Allakos
$0$424,552 -100.0%00.0%Medical

Showing largest 100 holdings. View all holdings.
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