Dafna Capital Management LLC Top Holdings and 13F Report (2023)

About Dafna Capital Management LLC

Investment Activity

Dafna Capital Management LLC has $393.41 million in total holdings as of June 30, 2023.
Dafna Capital Management LLC owns shares of 82 different stocks, but just 26 companies or ETFs make up 80% of its holdings.
Approximately 8.88% of the portfolio was purchased this quarter.
About 4.51% of the portfolio was sold this quarter.
This quarter, Dafna Capital Management LLC has purchased 84 new stocks and bought additional shares in 29 stocks.
Dafna Capital Management LLC sold shares of 20 stocks and completely divested from 8 stocks this quarter.

Largest Holdings

SPDR S&P Biotech ETF: $35,799,300
Stereotaxis: $31,191,663
Revolution Medicines: $27,607,638
AtriCure: $19,609,527
Merus: $18,998,358

Largest New Holdings this Quarter

TELA Bio: $4,351,908 Holding
BICARA THERAPEUTICS INC: $1,837,810 Holding
Align Technology: $1,146,805 Holding
Taysha Gene Therapies: $903,925 Holding
PALVELLA THERAPEUTICS INC: $857,424 Holding

Largest Purchases this Quarter

Revolution Medicines: 113,182 shares (about $4.95M)
TELA Bio: 1,441,029 shares (about $4.35M)
Blueprint Medicines: 28,000 shares (about $2.44M)
Ascendis Pharma A/S: 13,783 shares (about $1.90M)
BICARA THERAPEUTICS INC: 105,500 shares (about $1.84M)

Largest Sales this Quarter

Viking Therapeutics: 61,100 shares (about $2.46M)
Aquestive Therapeutics: 462,561 shares (about $1.65M)
Acelyrin: 514,905 shares (about $1.62M)
AxoGen: 89,012 shares (about $1.47M)
Centessa Pharmaceuticals: 72,898 shares (about $1.22M)

Sector Allocation Over Time

Selling

Neutral

Buying

Latest 13F Holdings and Changes Since Previous Quarterly Filing

Issuer Name	Holdings Value	Approximate Purchase/Sale	Change in Shares	Shares Held	% of Portfolio	Sector
XBI SPDR S&P Biotech ETF	$35,799,300	$360,240 ▼	-1.0%	397,505	9.1%	ETF
STXS Stereotaxis	$31,191,663		0.0%	13,680,554	7.9%	Medical
RVMD Revolution Medicines	$27,607,638	$4,950,581 ▲	21.9%	631,176	7.0%	Medical
ATRC AtriCure	$19,609,527		0.0%	641,673	5.0%	Medical
MRUS Merus	$18,998,358	$1,649,664 ▲	9.5%	451,804	4.8%	Medical
CYTK Cytokinetics	$18,726,624		0.0%	398,100	4.8%	Medical
ASND Ascendis Pharma A/S	$14,228,883	$1,897,506 ▲	15.4%	103,355	3.6%	Medical
AXGN AxoGen	$13,956,615	$1,466,918 ▼	-9.5%	846,882	3.5%	Medical
IBB iShares Biotechnology ETF	$13,551,525		0.0%	102,500	3.4%	Finance
BPMC Blueprint Medicines	$13,062,329	$2,442,160 ▲	23.0%	149,763	3.3%	Medical
IDYA IDEAYA Biosciences	$12,819,854	$704,617 ▲	5.8%	498,827	3.3%	Medical
XENE Xenon Pharmaceuticals	$10,730,569		0.0%	273,739	2.7%	Medical
NBIX Neurocrine Biosciences	$9,775,448	$273,000 ▲	2.9%	71,615	2.5%	Medical
DAWN Day One Biopharmaceuticals	$9,266,369	$240,730 ▼	-2.5%	731,363	2.4%	Medical
BHVN Biohaven	$8,225,777	$1,236,472 ▲	17.7%	220,235	2.1%	Medical
TNDM Tandem Diabetes Care	$8,039,952	$684,380 ▲	9.3%	223,208	2.0%	Medical
SNDX Syndax Pharmaceuticals	$7,165,266	$202,266 ▲	2.9%	542,002	1.8%	Medical
KALV KalVista Pharmaceuticals	$6,874,913	$745,360 ▲	12.2%	811,678	1.7%	Medical
URGN UroGen Pharma	$5,245,285	$357,840 ▲	7.3%	492,515	1.3%	Medical
DXCM DexCom	$5,097,979		0.0%	65,552	1.3%	Medical
BCRX BioCryst Pharmaceuticals	$5,015,840		0.0%	667,000	1.3%	Medical
EWTX Edgewise Therapeutics	$4,996,638	$1,088,452 ▼	-17.9%	187,140	1.3%	Medical
ASCENDIS PHARMA A/S	$4,412,500		0.0%	4,000,000	1.1%	NOTE 2.250% 4/0
TELA TELA Bio	$4,351,908	$4,351,908 ▲	New Holding	1,441,029	1.1%	Medical
PRQR ProQR Therapeutics	$4,154,037	$1,754,244 ▲	73.1%	1,567,561	1.1%	Medical
KURA Kura Oncology	$3,905,285	$348,400 ▲	9.8%	448,368	1.0%	Medical
RCUS Arcus Biosciences	$3,785,291	$37,225 ▼	-1.0%	254,217	1.0%	Medical
GLPG Galapagos	$3,579,813		0.0%	130,175	0.9%	Medical
ALKS Alkermes	$3,471,332		0.0%	120,700	0.9%	Medical
PODD Insulet	$3,237,268	$913,745 ▼	-22.0%	12,400	0.8%	Medical
ATXS Astria Therapeutics	$2,679,989	$407,753 ▲	17.9%	299,775	0.7%	Medical
IMVT Immunovant	$2,675,061	$1,387,120 ▲	107.7%	107,996	0.7%	Medical
ALLO Allogene Therapeutics	$2,641,451	$404,700 ▲	18.1%	1,240,118	0.7%	Medical
VKTX Viking Therapeutics	$2,596,124	$2,458,664 ▼	-48.6%	64,516	0.7%	Medical
LEXEO THERAPEUTICS INC	$2,586,486	$937,650 ▲	56.9%	393,083	0.7%	COM
ARAY Accuray	$2,420,269		0.0%	1,222,358	0.6%	Medical
KROS Keros Therapeutics	$2,062,902	$895,376 ▲	76.7%	130,316	0.5%	Medical
INGN Inogen	$1,914,604		0.0%	208,790	0.5%	Medical
STOK Stoke Therapeutics	$1,887,200	$400,720 ▼	-17.5%	171,097	0.5%	Medical
BICARA THERAPEUTICS INC	$1,837,810	$1,837,810 ▲	New Holding	105,500	0.5%	COM
BWAY BrainsWay	$1,821,951	$548,241 ▼	-23.1%	193,208	0.5%	Medical
MLYS Mineralys Therapeutics	$1,803,415		0.0%	146,500	0.5%	Medical
IMTX Immatics	$1,741,950	$711,000 ▲	69.0%	245,000	0.4%	Medical
ALEC Alector	$1,725,434		0.0%	912,928	0.4%	Medical
IPSC Century Therapeutics	$1,721,274		0.0%	1,704,232	0.4%	Medical
BCYC Bicycle Therapeutics	$1,691,186	$19,614 ▼	-1.1%	120,799	0.4%	Medical
ITOS iTeos Therapeutics	$1,446,505	$205,540 ▲	16.6%	188,347	0.4%	Medical
LRMR Larimar Therapeutics	$1,437,450	$475,391 ▼	-24.9%	371,434	0.4%	Medical
RGLS Regulus Therapeutics	$1,382,816	$31,600 ▼	-2.2%	875,200	0.4%	Medical
AUTL Autolus Therapeutics	$1,378,667	$235,000 ▲	20.5%	586,667	0.4%	Medical
GOSS Gossamer Bio	$1,274,818	$9,046 ▼	-0.7%	1,409,262	0.3%	Medical
TSVT 2seventy bio	$1,262,001	$590,284 ▼	-31.9%	429,252	0.3%	Medical
LCTX Lineage Cell Therapeutics	$1,261,965	$583,234 ▲	85.9%	2,511,374	0.3%	Medical
NEUROGENE INC	$1,177,290	$999,554 ▲	562.4%	51,500	0.3%	COM
MDWD MediWound	$1,147,726		0.0%	64,479	0.3%	Medical
ALGN Align Technology	$1,146,805	$1,146,805 ▲	New Holding	5,500	0.3%	Medical
BNTX BioNTech	$968,575		0.0%	8,500	0.2%	Medical
GPCR Structure Therapeutics	$962,760	$40,680 ▲	4.4%	35,500	0.2%	Medical
SPRY ARS Pharmaceuticals	$936,735	$627,768 ▼	-40.1%	88,790	0.2%	Medical
CMPS COMPASS Pathways	$919,334		0.0%	243,210	0.2%	Medical
TSHA Taysha Gene Therapies	$903,925	$903,925 ▲	New Holding	522,500	0.2%	Medical
POLYPID LTD	$885,470	$52,361 ▼	-5.6%	291,273	0.2%	COM
FHTX Foghorn Therapeutics	$881,304	$703,530 ▲	395.7%	186,717	0.2%	Medical
PALVELLA THERAPEUTICS INC	$857,424	$857,424 ▲	New Holding	71,452	0.2%	COM
STRO Sutro Biopharma	$804,225	$197,800 ▲	32.6%	437,079	0.2%	Medical
CNTA Centessa Pharmaceuticals	$794,838	$1,221,042 ▼	-60.6%	47,453	0.2%	Medical
VIR Vir Biotechnology	$734,000	$734,000 ▲	New Holding	100,000	0.2%	Medical
CGEN Compugen	$684,219		0.0%	447,202	0.2%	Medical
ACRV Acrivon Therapeutics	$676,732		0.0%	112,414	0.2%	Medical
SAGE Sage Therapeutics	$587,526		0.0%	108,200	0.1%	Medical
ACET Adicet Bio	$577,200		0.0%	600,000	0.1%	Medical
MASI Masimo	$495,900		0.0%	3,000	0.1%	Medical
AQST Aquestive Therapeutics	$452,120	$1,646,717 ▼	-78.5%	127,000	0.1%	Medical
APRE Aprea Therapeutics	$451,302		0.0%	137,174	0.1%	Medical
ADCT ADC Therapeutics	$445,921	$39,800 ▲	9.8%	224,081	0.1%	Medical
PERSPECTIVE THERAPEUTICS INC	$415,239	$319,488 ▼	-43.5%	130,169	0.1%	COM NEW
BDTX Black Diamond Therapeutics	$299,600	$32,100 ▲	12.0%	140,000	0.1%	Medical
BIOMX INC	$292,869		0.0%	401,136	0.1%	COM NEW
SLRN Acelyrin	$276,285	$1,616,799 ▼	-85.4%	87,989	0.1%	Medical
CMPX Compass Therapeutics	$229,671	$60,192 ▲	35.5%	158,394	0.1%	Medical
NVRO Nevro	$141,360		0.0%	38,000	0.0%	Medical
SPRO Spero Therapeutics	$128,750		0.0%	125,000	0.0%	Medical
NYXH Nyxoah	$0	$1,032,431 ▼	-100.0%	0	0.0%	Medical
GRAIL INC	$0	$671,488 ▼	-100.0%	0	0.0%	COM
TOURMALINE BIO INC	$0	$491,318 ▼	-100.0%	0	0.0%	COM
VSTM Verastem	$0	$381,823 ▼	-100.0%	0	0.0%	Medical
ADAP Adaptimmune Therapeutics	$0	$324,147 ▼	-100.0%	0	0.0%	Medical
ALTO NEUROSCIENCE INC	$0	$306,432 ▼	-100.0%	0	0.0%	COM SHS
STIM Neuronetics	$0	$238,362 ▼	-100.0%	0	0.0%	Medical
KPTI Karyopharm Therapeutics	$0	$159,923 ▼	-100.0%	0	0.0%	Medical

Showing largest 100 holdings. View all holdings.

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Dafna Capital Management LLC Top Holdings and 13F Report (2023)

About Dafna Capital Management LLC

Investment Activity

Largest Holdings

Largest New Holdings this Quarter

Largest Purchases this Quarter

Largest Sales this Quarter

Sector Allocation Over Time

Latest 13F Holdings and Changes Since Previous Quarterly Filing

More Institutional Buying and Selling Information

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Dafna Capital Management LLC Top Holdings and 13F Report (2023)

About Dafna Capital Management LLC

Investment Activity

Largest Holdings

Largest New Holdings this Quarter

Largest Purchases this Quarter

Largest Sales this Quarter

Sector Allocation Over Time

Map of 500 Largest Holdings ofDafna Capital Management LLC

Latest 13F Holdings and Changes Since Previous Quarterly Filing

More Institutional Buying and Selling Information

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools