Dafna Capital Management LLC Top Holdings and 13F Report (2023)

About Dafna Capital Management LLC

Investment Activity

Dafna Capital Management LLC has $423.31 million in total holdings as of June 30, 2023.
Dafna Capital Management LLC owns shares of 84 different stocks, but just 29 companies or ETFs make up 80% of its holdings.
Approximately 3.83% of the portfolio was purchased this quarter.
About 8.41% of the portfolio was sold this quarter.
This quarter, Dafna Capital Management LLC has purchased 83 new stocks and bought additional shares in 19 stocks.
Dafna Capital Management LLC sold shares of 26 stocks and completely divested from 5 stocks this quarter.

Largest Holdings

SPDR S&P Biotech ETF: $39,668,694
Stereotaxis: $27,908,330
Revolution Medicines: $23,491,028
Cytokinetics: $21,019,680
Merus: $20,612,147

Largest New Holdings this Quarter

LEXEO THERAPEUTICS INC: $2,265,270 Holding
BioNTech: $1,009,545 Holding
GRAIL INC: $671,488 Holding
Black Diamond Therapeutics: $543,750 Holding
BIOMX INC: $409,159 Holding

Largest Purchases this Quarter

LEXEO THERAPEUTICS INC: 250,583 shares (about $2.27M)
Blueprint Medicines: 17,000 shares (about $1.57M)
IDEAYA Biosciences: 49,197 shares (about $1.56M)
Ascendis Pharma A/S: 8,600 shares (about $1.28M)
Structure Therapeutics: 29,000 shares (about $1.27M)

Largest Sales this Quarter

SPDR S&P Biotech ETF: 43,500 shares (about $4.30M)
Viking Therapeutics: 63,501 shares (about $4.02M)
Syndax Pharmaceuticals: 130,372 shares (about $2.51M)
2seventy bio: 420,680 shares (about $1.99M)
Edgewise Therapeutics: 62,291 shares (about $1.66M)

Sector Allocation Over Time

Selling

Neutral

Buying

Latest 13F Holdings and Changes Since Previous Quarterly Filing

Issuer Name	Holdings Value	Approximate Purchase/Sale	Change in Shares	Shares Held	% of Portfolio	Sector
XBI SPDR S&P Biotech ETF	$39,668,694	$4,297,800 ▼	-9.8%	401,505	9.4%	ETF
STXS Stereotaxis	$27,908,330		0.0%	13,680,554	6.6%	Medical
RVMD Revolution Medicines	$23,491,028	$276,635 ▲	1.2%	517,994	5.5%	Medical
CYTK Cytokinetics	$21,019,680		0.0%	398,100	5.0%	Medical
MRUS Merus	$20,612,147	$156,275 ▲	0.8%	412,573	4.9%	Medical
ATRC AtriCure	$17,992,511	$70,100 ▲	0.4%	641,673	4.3%	Medical
IDYA IDEAYA Biosciences	$14,934,269	$1,558,561 ▲	11.7%	471,410	3.5%	Medical
IBB iShares Biotechnology ETF	$14,924,000		0.0%	102,500	3.5%	Finance
ASND Ascendis Pharma A/S	$13,373,995	$1,284,066 ▲	10.6%	89,572	3.2%	Medical
AXGN AxoGen	$13,121,234		0.0%	935,894	3.1%	Medical
BPMC Blueprint Medicines	$11,263,078	$1,572,500 ▲	16.2%	121,763	2.7%	Medical
XENE Xenon Pharmaceuticals	$10,777,104		0.0%	273,739	2.5%	Medical
DAWN Day One Biopharmaceuticals	$10,452,557	$1,168,727 ▲	12.6%	750,363	2.5%	Medical
SNDX Syndax Pharmaceuticals	$10,139,014	$2,509,661 ▼	-19.8%	526,702	2.4%	Medical
BHVN Biohaven	$9,350,886	$1,579,052 ▼	-14.4%	187,130	2.2%	Medical
TNDM Tandem Diabetes Care	$8,660,461		0.0%	204,208	2.0%	Medical
KALV KalVista Pharmaceuticals	$8,380,191	$964,556 ▼	-10.3%	723,678	2.0%	Medical
NBIX Neurocrine Biosciences	$8,021,040	$230,440 ▼	-2.8%	69,615	1.9%	Medical
KURA Kura Oncology	$7,979,511	$295,679 ▼	-3.6%	408,368	1.9%	Medical
VKTX Viking Therapeutics	$7,952,749	$4,020,248 ▼	-33.6%	125,616	1.9%	Medical
EWTX Edgewise Therapeutics	$6,082,811	$1,662,547 ▼	-21.5%	227,906	1.4%	Medical
URGN UroGen Pharma	$5,828,221	$128,080 ▼	-2.2%	458,915	1.4%	Medical
BCRX BioCryst Pharmaceuticals	$5,069,200	$285,000 ▼	-5.3%	667,000	1.2%	Medical
ASCENDIS PHARMA A/S	$4,680,000		0.0%	4,000,000	1.1%	NOTE 2.250% 4/0
DXCM DexCom	$4,394,606		0.0%	65,552	1.0%	Medical
KROS Keros Therapeutics	$4,282,895	$348,420 ▲	8.9%	73,754	1.0%	Medical
ALEC Alector	$4,254,244		0.0%	912,928	1.0%	Medical
RCUS Arcus Biosciences	$3,925,203	$53,515 ▲	1.4%	256,717	0.9%	Medical
GLPG Galapagos	$3,747,738		0.0%	130,175	0.9%	Medical
PODD Insulet	$3,700,725		0.0%	15,900	0.9%	Medical
ALKS Alkermes	$3,378,393		0.0%	120,700	0.8%	Medical
LRMR Larimar Therapeutics	$3,237,495	$954,335 ▼	-22.8%	494,274	0.8%	Medical
PERSPECTIVE THERAPEUTICS INC	$3,074,799	$17,515 ▼	-0.6%	230,322	0.7%	COM NEW
TSVT 2seventy bio	$2,973,737	$1,985,610 ▼	-40.0%	630,029	0.7%	Medical
SLRN Acelyrin	$2,972,267	$447,225 ▼	-13.1%	602,894	0.7%	Medical
ALLO Allogene Therapeutics	$2,940,330	$1,246,050 ▲	73.5%	1,050,118	0.7%	Medical
AQST Aquestive Therapeutics	$2,936,014	$296,614 ▲	11.2%	589,561	0.7%	Medical
IPSC Century Therapeutics	$2,914,237		0.0%	1,704,232	0.7%	Medical
ATXS Astria Therapeutics	$2,798,357	$220,200 ▼	-7.3%	254,165	0.7%	Medical
BCYC Bicycle Therapeutics	$2,765,386		0.0%	122,200	0.7%	Medical
STOK Stoke Therapeutics	$2,549,278		0.0%	207,427	0.6%	Medical
BWAY BrainsWay	$2,322,437	$427,895 ▼	-15.6%	251,346	0.5%	Medical
LEXEO THERAPEUTICS INC	$2,265,270	$2,265,270 ▲	New Holding	250,583	0.5%	COM
ARAY Accuray	$2,200,244		0.0%	1,222,358	0.5%	Medical
SPRY ARS Pharmaceuticals	$2,150,263	$1,318,050 ▼	-38.0%	148,294	0.5%	Medical
INGN Inogen	$2,025,263		0.0%	208,790	0.5%	Medical
CNTA Centessa Pharmaceuticals	$1,924,412	$40,471 ▼	-2.1%	120,351	0.5%	Medical
MLYS Mineralys Therapeutics	$1,774,115	$333,025 ▲	23.1%	146,500	0.4%	Medical
AUTL Autolus Therapeutics	$1,766,601	$508,200 ▲	40.4%	486,667	0.4%	Medical
IMTX Immatics	$1,654,450		0.0%	145,000	0.4%	Medical
ITOS iTeos Therapeutics	$1,649,773	$175,857 ▲	11.9%	161,584	0.4%	Medical
PRQR ProQR Therapeutics	$1,648,159		0.0%	905,582	0.4%	Medical
CMPS COMPASS Pathways	$1,532,223		0.0%	243,210	0.4%	Medical
GPCR Structure Therapeutics	$1,492,260	$1,272,810 ▲	580.0%	34,000	0.4%	Medical
IMVT Immunovant	$1,482,406	$116,321 ▲	8.5%	51,996	0.4%	Medical
RGLS Regulus Therapeutics	$1,405,464		0.0%	895,200	0.3%	Medical
GOSS Gossamer Bio	$1,399,960	$9,864 ▲	0.7%	1,419,262	0.3%	Medical
LCTX Lineage Cell Therapeutics	$1,222,796		0.0%	1,350,708	0.3%	Medical
MDWD MediWound	$1,164,491	$1,083,600 ▼	-48.2%	64,479	0.3%	Medical
STRO Sutro Biopharma	$1,140,343		0.0%	329,579	0.3%	Medical
POLYPID LTD	$1,061,230	$425,360 ▲	66.9%	308,497	0.3%	COM
NYXH Nyxoah	$1,032,431		0.0%	108,108	0.2%	Medical
BNTX BioNTech	$1,009,545	$1,009,545 ▲	New Holding	8,500	0.2%	Medical
ACET Adicet Bio	$864,000		0.0%	600,000	0.2%	Medical
CGEN Compugen	$809,436	$27,150 ▼	-3.2%	447,202	0.2%	Medical
ACRV Acrivon Therapeutics	$786,898	$62,559 ▼	-7.4%	112,414	0.2%	Medical
SAGE Sage Therapeutics	$781,204	$57,760 ▼	-6.9%	108,200	0.2%	Medical
GRAIL INC	$671,488	$671,488 ▲	New Holding	48,800	0.2%	COM
ADCT ADC Therapeutics	$642,855		0.0%	204,081	0.2%	Medical
BDTX Black Diamond Therapeutics	$543,750	$543,750 ▲	New Holding	125,000	0.1%	Medical
TOURMALINE BIO INC	$491,318	$1,462,179 ▼	-74.8%	19,110	0.1%	COM
BIOMX INC	$409,159	$409,159 ▲	New Holding	401,136	0.1%	COM NEW
MASI Masimo	$399,990		0.0%	3,000	0.1%	Medical
VSTM Verastem	$381,823	$381,823 ▲	New Holding	127,700	0.1%	Medical
APRE Aprea Therapeutics	$377,229		0.0%	137,174	0.1%	Medical
FHTX Foghorn Therapeutics	$350,652	$38,972 ▼	-10.0%	37,664	0.1%	Medical
NEUROGENE INC	$326,239	$135,321 ▼	-29.3%	7,775	0.1%	COM
ADAP Adaptimmune Therapeutics	$324,147		0.0%	341,064	0.1%	Medical
ALTO NEUROSCIENCE INC	$306,432	$1,066,369 ▼	-77.7%	26,786	0.1%	COM SHS
STIM Neuronetics	$238,362		0.0%	313,717	0.1%	Medical
CMPX Compass Therapeutics	$215,063		0.0%	116,882	0.1%	Medical
NVRO Nevro	$212,420	$55,900 ▲	35.7%	38,000	0.1%	Medical
SPRO Spero Therapeutics	$167,500		0.0%	125,000	0.0%	Medical
KPTI Karyopharm Therapeutics	$159,923		0.0%	192,678	0.0%	Medical
MORF Morphic	$0	$7,895,654 ▼	-100.0%	0	0.0%	Medical
PRCT PROCEPT BioRobotics	$0	$854,893 ▼	-100.0%	0	0.0%	Medical
SYRS Syros Pharmaceuticals	$0	$700,986 ▼	-100.0%	0	0.0%	Medical
TERN Terns Pharmaceuticals	$0	$585,660 ▼	-100.0%	0	0.0%	Medical
ORIC ORIC Pharmaceuticals	$0	$254,520 ▼	-100.0%	0	0.0%	Medical

Showing largest 100 holdings. View all holdings.

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Dafna Capital Management LLC Top Holdings and 13F Report (2023)

About Dafna Capital Management LLC

Investment Activity

Largest Holdings

Largest New Holdings this Quarter

Largest Purchases this Quarter

Largest Sales this Quarter

Sector Allocation Over Time

Latest 13F Holdings and Changes Since Previous Quarterly Filing

More Institutional Buying and Selling Information

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Dafna Capital Management LLC Top Holdings and 13F Report (2023)

About Dafna Capital Management LLC

Investment Activity

Largest Holdings

Largest New Holdings this Quarter

Largest Purchases this Quarter

Largest Sales this Quarter

Sector Allocation Over Time

Map of 500 Largest Holdings ofDafna Capital Management LLC

Latest 13F Holdings and Changes Since Previous Quarterly Filing

More Institutional Buying and Selling Information

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools