Deerfield Management Company, L.P. (Series C) Top Holdings and 13F Report (2025) About Deerfield Management Company, L.P. (Series C)Investment ActivityDeerfield Management Company, L.P. (Series C) has $5.28 billion in total holdings as of December 31, 2024.Deerfield Management Company, L.P. (Series C) owns shares of 106 different stocks, but just 27 companies or ETFs make up 80% of its holdings.Approximately 10.28% of the portfolio was purchased this quarter.About 21.16% of the portfolio was sold this quarter.This quarter, Deerfield Management Company, L.P. (Series C) has purchased 443 new stocks and bought additional shares in 25 stocks.Deerfield Management Company, L.P. (Series C) sold shares of 25 stocks and completely divested from 360 stocks this quarter.Largest Holdings Nuvalent $1,408,337,359Viatris $298,750,648INTEGRA LIFESCIENCES HLDGS C $168,179,309Centene $161,864,974Oscar Health $159,062,400 Largest New Holdings this Quarter Legend Biotech $50,492,904 HoldingKymera Therapeutics $23,856,390 HoldingEstablishment Labs $23,035,000 HoldingSEPTERNA INC $19,735,541 HoldingiRhythm Technologies $14,067,602 Holding Largest Purchases this Quarter NewAmsterdam Pharma 3,412,590 shares (about $87.70M)Dynavax Technologies 5,172,263 shares (about $66.05M)Oscar Health 3,983,325 shares (about $53.54M)Legend Biotech 1,551,718 shares (about $50.49M)Indivior 3,790,518 shares (about $47.12M) Largest Sales this Quarter Nuvalent 2,000,000 shares (about $156.56M)Catalyst Pharmaceuticals 3,096,623 shares (about $64.63M)ALPHATEC HLDGS INC 68,000,000 shares (about $64.17M)Neurocrine Biosciences 454,590 shares (about $62.05M)WAYSTAR HLDG CORP 1,656,744 shares (about $60.80M) Sector Allocation Over TimeMap of 500 Largest Holdings ofDeerfield Management Company, L.P. (Series C) Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorNUVLNuvalent$1,408,337,359$156,560,000 ▼-10.0%17,991,02426.7%MedicalVTRSViatris$298,750,648$37,512 ▲0.0%23,996,0365.7%MedicalINTEGRA LIFESCIENCES HLDGS C$168,179,3090.0%174,364,0003.2%NOTE 0.500% 8/1CNCCentene$161,864,974$1,195,365 ▲0.7%2,671,9213.1%MedicalOSCROscar Health$159,062,400$53,535,888 ▲50.7%11,835,0003.0%FinanceRVMDRevolution Medicines$142,519,442$15,118,294 ▲11.9%3,258,3322.7%MedicalMRUSMerus$125,005,693$18,323,372 ▼-12.8%2,972,7872.4%MedicalACCOLADE INC$124,471,0690.0%132,598,0002.4%NOTE 0.500% 4/0WAYSTAR HLDG CORP$120,936,042$60,802,505 ▼-33.5%3,295,2602.3%COMNBIXNeurocrine Biosciences$117,663,000$62,051,535 ▼-34.5%862,0002.2%MedicalALNYLAM PHARMACEUTICALS INC$117,307,300$10,664,300 ▲10.0%110,000,0002.2%NOTE 1.000% 9/1SPRYARS Pharmaceuticals$110,929,631$5,942,498 ▼-5.1%10,514,6572.1%MedicalNAMSNewAmsterdam Pharma$110,878,538$87,703,563 ▲378.4%4,314,3402.1%MedicalINDVIndivior$110,417,679$47,116,139 ▲74.4%8,883,1602.1%MedicalMIRUM PHARMACEUTICALS INC$106,576,4000.0%70,000,0002.0%NOTE 4.000% 5/0AHCOAdaptHealth$92,452,6230.0%9,711,4101.8%MedicalALHCAlignment Healthcare$82,173,398$39,945,184 ▼-32.7%7,304,3021.6%MedicalLRMRLarimar Therapeutics$82,167,7390.0%21,231,9741.6%MedicalBKDBrookdale Senior Living$78,529,6880.0%15,612,2641.5%MedicalIDYAIDEAYA Biosciences$70,315,200$3,649,400 ▲5.5%2,736,0001.3%MedicalEMBCEmbecta$67,536,548$11,154,965 ▲19.8%3,270,5351.3%MedicalDVAXDynavax Technologies$66,325,120$66,049,799 ▲23,990.1%5,193,8231.3%MedicalCPRXCatalyst Pharmaceuticals$65,385,940$64,626,522 ▼-49.7%3,133,0111.2%MedicalOMIOwens & Minor$64,199,5660.0%4,911,9791.2%MedicalBCRXBioCryst Pharmaceuticals$61,246,204$64,958 ▲0.1%8,144,4421.2%MedicalBAXBaxter International$56,077,5960.0%1,923,1001.1%MedicalEWTXEdgewise Therapeutics$55,496,190$7,943,330 ▲16.7%2,078,5091.1%MedicalLEGNLegend Biotech$50,492,904$50,492,904 ▲New Holding1,551,7181.0%MedicalBIOBio-Rad Laboratories$49,816,570$22,667 ▲0.0%151,6440.9%MedicalALPHATEC HLDGS INC$46,711,170$64,168,880 ▼-57.9%49,500,0000.9%NOTE 0.750% 8/0CNMDCONMED$41,882,816$200,255 ▼-0.5%611,9640.8%MedicalCGEMCullinan Therapeutics$41,161,080$1,210,680 ▲3.0%3,379,3990.8%MedicalEHABEnhabit$39,135,691$103,295 ▲0.3%5,010,9720.7%MedicalGLPGGalapagos$38,802,5000.0%1,411,0000.7%MedicalPHVSPharvaris$38,674,785$272,904 ▼-0.7%2,017,4640.7%MedicalIRONDisc Medicine$38,072,651$26,802,350 ▼-41.3%600,5150.7%MedicalALNYAlnylam Pharmaceuticals$34,164,894$44,944 ▲0.1%145,1910.6%MedicalLANTHEUS HLDGS INC$33,708,6060.0%25,255,0000.6%NOTE 2.625%12/1DAWNDay One Biopharmaceuticals$32,891,738$274,686 ▼-0.8%2,596,0330.6%MedicalPHRPhreesia$31,999,293$18,300,981 ▲133.6%1,271,8320.6%MedicalBICARA THERAPEUTICS INC$31,271,9310.0%1,795,1740.6%COMDCGODocGo$30,510,853$7,929,572 ▼-20.6%7,195,9560.6%MedicalINMDInMode$26,364,4240.0%1,578,7080.5%MedicalSVRASavara$24,449,480$4,599,545 ▲23.2%7,964,0000.5%MedicalCG ONCOLOGY INC$24,423,687$25,755 ▲0.1%851,5930.5%COMKYMRKymera Therapeutics$23,856,390$23,856,390 ▲New Holding593,0000.5%MedicalMREOMereo BioPharma Group$23,486,5020.0%6,710,4290.4%MedicalESTAEstablishment Labs$23,035,000$23,035,000 ▲New Holding500,0000.4%MedicalTXG10x Genomics$21,496,920$171,501 ▼-0.8%1,497,0000.4%MedicalLNTHLantheus$21,489,9020.0%240,2180.4%MedicalCOGTCogent Biosciences$20,521,800$8,683,451 ▼-29.7%2,631,0000.4%MedicalSEPTERNA INC$19,735,541$19,735,541 ▲New Holding861,8140.4%COMNVSTEnvista$19,645,225$19,256,204 ▲4,949.9%1,018,4150.4%MedicalPCVXVaxcyte$18,418,5000.0%225,0000.3%MedicalRXRXRecursion Pharmaceuticals$15,649,4000.0%2,315,0000.3%MedicalFHTXFoghorn Therapeutics$15,366,026$1,074,404 ▲7.5%3,255,5140.3%MedicalIRTCiRhythm Technologies$14,067,602$14,067,602 ▲New Holding156,0120.3%MedicalCMRXChimerix$13,124,270$13,124,270 ▲New Holding3,771,3420.2%MedicalCONCENTRA GROUP HOLDINGS PAR$12,857,0000.0%650,0000.2%COMMON STOCKZENAS BIOPHARMA INC$12,800,4950.0%1,562,9420.2%COMACCDAccolade$11,884,5000.0%3,475,0000.2%Business ServicesTHRDTF Financial$10,492,713$10,492,713 ▲New Holding1,019,7000.2%MedicalSPYRE THERAPEUTICS INC$10,476,000$10,476,000 ▲New Holding450,0000.2%COM NEWLUNGPulmonx$10,421,041$10,421,041 ▲New Holding1,534,7630.2%MedicalDYNE THERAPEUTICS INC$10,263,9850.0%435,6530.2%COMNEUROGENE INC$10,244,595$10,244,595 ▲New Holding448,1450.2%COMGPCRStructure Therapeutics$10,126,798$12,773,520 ▼-55.8%373,4070.2%MedicalPERSPECTIVE THERAPEUTICS INC$9,374,625$385,961 ▲4.3%2,938,7540.2%COM NEWFATEFate Therapeutics$5,867,1870.0%3,555,8710.1%MedicalNKTXNkarta$5,365,9500.0%2,155,0000.1%MedicalCRVSCorvus Pharmaceuticals$5,350,000$5,350,000 ▲New Holding1,000,0000.1%MedicalCALCCalciMedica$4,602,000$1,062,000 ▲30.0%1,300,0000.1%MedicalHLVXHilleVax$3,897,0940.0%1,882,6540.1%MedicalSINGULAR GENOMICS SYSTEMS IN$3,228,5280.0%166,1620.1%COM NEWANNXAnnexon$2,995,4740.0%583,9130.1%MedicalALECAlector$2,016,558$22,245 ▲1.1%1,066,9620.0%MedicalNAMSWNewAmsterdam Pharma$1,322,2150.0%92,7870.0%MedicalBIOMX INC$1,305,1340.0%1,787,6100.0%COM NEWVTYXVentyx Biosciences$1,171,074$13,535,873 ▼-92.0%534,7370.0%MedicalTWSTTwist Bioscience$1,107,241$18,727 ▲1.7%23,8270.0%MedicalTOIOncology Institute$1,038,2560.0%3,360,0520.0%MedicalQSIAWQuantum-Si$416,6660.0%333,3330.0%MedicalHUMHumana$232,652$232,652 ▲New Holding9170.0%MedicalGISGeneral Mills$220,325$220,325 ▲New Holding3,4550.0%Consumer StaplesENLCEnLink Midstream$145,137$145,137 ▲New Holding10,2570.0%Oils/EnergyHNSTHonest$139,785$1,230,664 ▼-89.8%20,1710.0%Consumer DiscretionaryEBSEmergent BioSolutions$134,394$588,741 ▼-81.4%14,0580.0%MedicalHTLDHeartland Express$129,557$631,471 ▼-83.0%11,5470.0%TransportationUISUnisys$98,919$98,919 ▲New Holding15,6270.0%Computer and TechnologyBUTTERFLY NETWORK INC$93,2070.0%733,3330.0%*W EXP 02/12/202EGYVAALCO Energy$91,320$91,320 ▲New Holding20,8970.0%Oils/EnergyHBIHanesbrands$86,439$591,121 ▼-87.2%10,6190.0%Consumer DiscretionaryGNWGenworth Financial$79,036$256,435 ▼-76.4%11,3070.0%FinanceECVTEcovyst$78,822$78,822 ▲New Holding10,3170.0%Business ServicesCERSCerus$77,470$77,470 ▲New Holding50,3050.0%MedicalEQCEquity Commonwealth$76,567$76,567 ▲New Holding43,2580.0%FinanceACCOACCO Brands$76,424$469,075 ▼-86.0%14,5570.0%Industrial ProductsOSUROraSure Technologies$75,442$508,701 ▼-87.1%20,8980.0%MedicalNUSNu Skin Enterprises$70,237$874,697 ▼-92.6%10,1940.0%Consumer StaplesGDRXGoodRx$55,754$55,754 ▲New Holding11,9900.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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