Frazier Life Sciences Management, L.P. Top Holdings and 13F Report (2024) About Frazier Life Sciences Management, L.P.Investment ActivityFrazier Life Sciences Management, L.P. has $2.50 billion in total holdings as of September 30, 2024.Frazier Life Sciences Management, L.P. owns shares of 53 different stocks, but just 19 companies or ETFs make up 80% of its holdings.Approximately 11.56% of the portfolio was purchased this quarter.About 3.41% of the portfolio was sold this quarter.This quarter, Frazier Life Sciences Management, L.P. has purchased 49 new stocks and bought additional shares in 13 stocks.Frazier Life Sciences Management, L.P. sold shares of 5 stocks and completely divested from 4 stocks this quarter.Largest Holdings Mirum Pharmaceuticals $256,245,288NewAmsterdam Pharma $213,396,220Phathom Pharmaceuticals $182,775,764Krystal Biotech $179,929,374MBX BIOSCIENCES INC $155,499,315 Largest New Holdings this Quarter MBX BIOSCIENCES INC $155,499,315 HoldingAscendis Pharma A/S $19,907,950 HoldingAlkermes $16,125,851 HoldingORUKA THERAPEUTICS INC $11,699,285 HoldingLEXEO THERAPEUTICS INC $11,307,105 Holding Largest Purchases this Quarter MBX BIOSCIENCES INC 5,985,347 shares (about $155.50M)Ascendis Pharma A/S 133,333 shares (about $19.91M)Alkermes 576,129 shares (about $16.13M)ORUKA THERAPEUTICS INC 477,327 shares (about $11.70M)Ultragenyx Pharmaceutical 208,715 shares (about $11.59M) Largest Sales this Quarter Edgewise Therapeutics 898,200 shares (about $23.97M)Vaxcyte 160,000 shares (about $18.28M)PepGen 800,094 shares (about $6.84M)Tyra Biosciences 101,200 shares (about $2.38M)Rocket Pharmaceuticals 75,600 shares (about $1.40M) Sector Allocation Over TimeMap of 500 Largest Holdings ofFrazier Life Sciences Management, L.P. Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorMIRMMirum Pharmaceuticals$256,245,288$2,925,000 ▲1.2%6,570,39210.3%MedicalNAMSNewAmsterdam Pharma$213,396,220$10,428,967 ▲5.1%12,855,1948.6%MedicalPHATPhathom Pharmaceuticals$182,775,7640.0%10,109,2797.3%MedicalKRYSKrystal Biotech$179,929,3740.0%988,4607.2%MedicalMBX BIOSCIENCES INC$155,499,315$155,499,315 ▲New Holding5,985,3476.2%COMRYTMRhythm Pharmaceuticals$126,624,115$2,391,499 ▲1.9%2,416,9525.1%MedicalPCVXVaxcyte$100,489,609$18,283,200 ▼-15.4%879,4054.0%MedicalVRNAVerona Pharma$97,356,242$2,002,421 ▲2.1%3,383,9503.9%MedicalBBIOBridgeBio Pharma$95,741,235$3,255,137 ▲3.5%3,760,4573.8%MedicalIRONDisc Medicine$86,232,5430.0%1,754,8343.5%MedicalARQTArcutis Biotherapeutics$81,703,1410.0%8,785,2843.3%MedicalEWTXEdgewise Therapeutics$75,609,220$23,972,958 ▼-24.1%2,832,8673.0%MedicalANABAnaptysBio$74,007,832$1,460,533 ▲2.0%2,209,1893.0%MedicalERASErasca$52,939,306$8,669,036 ▲19.6%19,391,6872.1%MedicalTARSTarsus Pharmaceuticals$52,213,7630.0%1,587,5272.1%MedicalAGIOAgios Pharmaceuticals$46,391,762$7,649,957 ▲19.7%1,044,1541.9%MedicalRVMDRevolution Medicines$45,234,5840.0%997,4551.8%MedicalSLNOSoleno Therapeutics$44,212,4270.0%875,6671.8%MedicalKALVKalVista Pharmaceuticals$42,705,5000.0%3,687,8671.7%MedicalORICORIC Pharmaceuticals$42,464,2640.0%4,142,8551.7%MedicalRAREUltragenyx Pharmaceutical$35,202,868$11,594,118 ▲49.1%633,7151.4%MedicalSVRASavara$34,587,3120.0%8,157,3851.4%MedicalCG ONCOLOGY INC$29,052,1000.0%770,0001.2%COMRCKTRocket Pharmaceuticals$27,439,586$1,396,332 ▼-4.8%1,485,6301.1%MedicalTRVITrevi Therapeutics$24,652,8410.0%7,381,0901.0%MedicalMREOMereo BioPharma Group$20,951,872$2,862,237 ▲15.8%5,097,7790.8%MedicalSLNSilence Therapeutics$20,881,3840.0%1,148,5910.8%MedicalASNDAscendis Pharma A/S$19,907,950$19,907,950 ▲New Holding133,3330.8%MedicalHLVXHilleVax$18,686,0290.0%10,617,0620.7%MedicalMRUSMerus$18,640,0760.0%373,1000.7%MedicalTYRATyra Biosciences$17,186,280$2,379,212 ▼-12.2%731,0200.7%MedicalAUTLAutolus Therapeutics$16,782,6660.0%4,623,3240.7%MedicalALKSAlkermes$16,125,851$16,125,851 ▲New Holding576,1290.6%MedicalIMTXImmatics$15,457,253$2,307,730 ▲17.5%1,354,7110.6%MedicalORUKA THERAPEUTICS INC$11,699,285$11,699,285 ▲New Holding477,3270.5%COMLEXEO THERAPEUTICS INC$11,307,105$11,307,105 ▲New Holding1,250,7860.5%COMDSGNDesign Therapeutics$10,181,903$3,751,840 ▲58.3%1,892,5470.4%MedicalCOGTCogent Biosciences$10,115,0210.0%936,5760.4%MedicalMGNXMacroGenics$9,905,2920.0%3,010,7270.4%MedicalDAWNDay One Biopharmaceuticals$9,606,894$9,606,894 ▲New Holding689,6550.4%MedicalALLOAllogene Therapeutics$8,029,7000.0%2,867,7500.3%MedicalPBYIPuma Biotechnology$7,809,5230.0%3,062,5580.3%MedicalADVERUM BIOTECHNOLOGIES INC$7,506,0930.0%1,069,2440.3%COM NEWETNB89bio$7,400,0000.0%1,000,0000.3%MedicalACADACADIA Pharmaceuticals$7,233,7980.0%470,3380.3%MedicalARVNArvinas$7,027,7030.0%285,3310.3%MedicalPEPGPepGen$6,008,034$6,840,804 ▼-53.2%702,6940.2%MedicalELEVElevation Oncology$3,595,548$1,820,696 ▲102.6%5,993,5790.1%MedicalNAMSWNewAmsterdam Pharma$3,502,3310.0%500,3330.1%MedicalIMCRImmunocore$3,385,7610.0%108,7620.1%MedicalNUVBNuvation Bio$2,789,760$2,789,760 ▲New Holding1,218,2360.1%MedicalACRSAclaris Therapeutics$304,0340.0%264,3770.0%MedicalPIERIS PHARMACEUTICALS INC$266,869$266,869 ▲New Holding15,9420.0%COM NEWCERECerevel Therapeutics$0$16,069,770 ▼-100.0%00.0%MedicalAPLTApplied Therapeutics$0$10,676,250 ▼-100.0%00.0%MedicalANTX(ANTX)$0$4,491,111 ▼-100.0%00.0%MedicalMETAGENOMI INC$0$1,002,423 ▼-100.0%00.0%COMShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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