Ghost Tree Capital, LLC Top Holdings and 13F Report (2024) About Ghost Tree Capital, LLCInvestment ActivityGhost Tree Capital, LLC has $331.04 million in total holdings as of September 30, 2024.Ghost Tree Capital, LLC owns shares of 52 different stocks, but just 27 companies or ETFs make up 80% of its holdings.Approximately 37.41% of the portfolio was purchased this quarter.About 43.60% of the portfolio was sold this quarter.This quarter, Ghost Tree Capital, LLC has purchased 60 new stocks and bought additional shares in 16 stocks.Ghost Tree Capital, LLC sold shares of 22 stocks and completely divested from 19 stocks this quarter.Largest Holdings SPDR S&P Biotech ETF $29,640,000BIOHAVEN LTD $17,428,437Sarepta Therapeutics $14,986,800Novo Nordisk A/S $13,097,700Blueprint Medicines $12,950,000 Largest New Holdings this Quarter SPDR S&P Biotech ETF $29,640,000 HoldingBIOHAVEN LTD $17,428,437 HoldingNovo Nordisk A/S $13,097,700 HoldingEdgewise Therapeutics $5,204,550 HoldingDYNE THERAPEUTICS INC $3,592,000 Holding Largest Purchases this Quarter SPDR S&P Biotech ETF 300,000 shares (about $29.64M)BIOHAVEN LTD 348,778 shares (about $17.43M)Novo Nordisk A/S 110,000 shares (about $13.10M)Blueprint Medicines 100,000 shares (about $9.25M)Sarepta Therapeutics 65,000 shares (about $8.12M) Largest Sales this Quarter Viridian Therapeutics 512,708 shares (about $11.66M)Insmed 140,000 shares (about $10.22M)MoonLake Immunotherapeutics 171,589 shares (about $8.65M)Vaxcyte 70,000 shares (about $8.00M)Soleno Therapeutics 150,000 shares (about $7.57M) Sector Allocation Over TimeMap of 500 Largest Holdings ofGhost Tree Capital, LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorXBISPDR S&P Biotech ETF$29,640,000$29,640,000 ▲New Holding300,0009.0%ETFBIOHAVEN LTD$17,428,437$17,428,437 ▲New Holding348,7785.3%CALLSRPTSarepta Therapeutics$14,986,800$8,117,850 ▲118.2%120,0004.5%MedicalNVONovo Nordisk A/S$13,097,700$13,097,700 ▲New Holding110,0004.0%MedicalBPMCBlueprint Medicines$12,950,000$9,250,000 ▲250.0%140,0003.9%MedicalAXSMAxsome Therapeutics$12,132,450$1,348,050 ▼-10.0%135,0003.7%MedicalTARSTarsus Pharmaceuticals$11,511,500$3,782,350 ▲48.9%350,0003.5%MedicalPERSPECTIVE THERAPEUTICS INC$10,012,500$2,336,250 ▼-18.9%750,0003.0%COM NEWCG ONCOLOGY INC$9,432,500$377,300 ▼-3.8%250,0002.8%COMROIVRoivant Sciences$9,232,000$2,308,000 ▼-20.0%800,0002.8%MedicalPCVXVaxcyte$9,141,600$7,998,900 ▼-46.7%80,0002.8%MedicalINSMInsmed$9,125,000$10,220,000 ▼-52.8%125,0002.8%MedicalVKTXViking Therapeutics$8,863,400$2,848,950 ▲47.4%140,0002.7%MedicalSNDXSyndax Pharmaceuticals$8,662,500$1,925,000 ▲28.6%450,0002.6%MedicalJANXJanux Therapeutics$8,631,700$6,360,200 ▲280.0%190,0002.6%MedicalCRBPCorbus Pharmaceuticals$7,839,400$4,229,150 ▲117.1%380,0002.4%MedicalASNDAscendis Pharma A/S$7,838,775$5,109,538 ▼-39.5%52,5002.4%MedicalCRNXCrinetics Pharmaceuticals$7,665,000$4,599,000 ▼-37.5%150,0002.3%MedicalSLNOSoleno Therapeutics$7,573,500$7,573,500 ▼-50.0%150,0002.3%MedicalTGTXTG Therapeutics$7,250,900$4,444,100 ▼-38.0%310,0002.2%MedicalRZLTRezolute$7,153,726$259,446 ▲3.8%1,474,9952.2%MedicalPHATPhathom Pharmaceuticals$6,780,000$4,068,000 ▼-37.5%375,0002.0%MedicalMLTXMoonLake Immunotherapeutics$6,474,483$8,651,518 ▼-57.2%128,4112.0%MedicalOLMAOlema Pharmaceuticals$6,387,900$179,100 ▼-2.7%535,0001.9%MedicalIMVTImmunovant$6,129,650$1,282,950 ▼-17.3%215,0001.9%MedicalEWTXEdgewise Therapeutics$5,204,550$5,204,550 ▲New Holding195,0001.6%MedicalREPLReplimune Group$4,932,0000.0%450,0001.5%MedicalBBIOBridgeBio Pharma$4,455,500$891,100 ▲25.0%175,0001.3%MedicalTSHATaysha Gene Therapies$4,321,500$1,809,000 ▲72.0%2,150,0001.3%MedicalRYTMRhythm Pharmaceuticals$4,130,532$2,019,425 ▼-32.8%78,8421.2%MedicalANNXAnnexon$3,848,000$742,960 ▲23.9%650,0001.2%MedicalKORRO BIO INC$3,676,200$334,200 ▲10.0%110,0001.1%COMDYNE THERAPEUTICS INC$3,592,000$3,592,000 ▲New Holding100,0001.1%COMARVNArvinas$3,571,350$1,724,100 ▲93.3%145,0001.1%MedicalHELIX ACQUISITION CORP II$3,134,9880.0%300,0000.9%CL A ORD SHSNUVBNuvation Bio$3,091,500$458,000 ▲17.4%1,350,0000.9%MedicalSVRASavara$3,074,000$1,381,714 ▼-31.0%725,0000.9%MedicalTNYATenaya Therapeutics$2,895,000$289,500 ▲11.1%1,500,0000.9%MedicalRGNXREGENXBIO$2,779,850$996,550 ▲55.9%265,0000.8%MedicalCRVSCorvus Pharmaceuticals$2,640,000$2,640,000 ▲New Holding500,0000.8%MedicalABSIAbsci$2,101,000$2,101,000 ▲New Holding550,0000.6%MedicalNEUROGENE INC$2,098,000$839,200 ▼-28.6%50,0000.6%COMCAPRCapricor Therapeutics$1,901,250$1,901,250 ▲New Holding125,0000.6%MedicalAPLSApellis Pharmaceuticals$1,874,600$2,018,800 ▼-51.9%65,0000.6%MedicalSMMTSummit Therapeutics$1,861,500$1,861,500 ▲New Holding85,0000.6%MedicalSPYRE THERAPEUTICS INC$1,764,600$5,594,870 ▼-76.0%60,0000.5%COM NEWVRDNViridian Therapeutics$1,706,250$11,664,107 ▼-87.2%75,0000.5%MedicalPRQRProQR Therapeutics$1,615,614$22,386 ▼-1.4%887,7000.5%MedicalLIFEaTyr Pharma$1,408,0000.0%800,0000.4%MedicalLRMRLarimar Therapeutics$1,310,000$1,310,000 ▲New Holding200,0000.4%MedicalENGENE HOLDINGS INC$1,061,927$1,712,258 ▼-61.7%160,8980.3%COMAMLXAmylyx Pharmaceuticals$1,053,000$1,053,000 ▲New Holding325,0000.3%MedicalALNYAlnylam Pharmaceuticals$0$22,088,700 ▼-100.0%00.0%MedicalBHVNBiohaven$0$17,007,900 ▼-100.0%00.0%MedicalACADACADIA Pharmaceuticals$0$3,656,250 ▼-100.0%00.0%MedicalCABACabaletta Bio$0$2,774,325 ▼-100.0%00.0%MedicalCYTKCytokinetics$0$1,798,776 ▼-100.0%00.0%MedicalELEVElevation Oncology$0$1,620,000 ▼-100.0%00.0%MedicalKRYSKrystal Biotech$0$1,560,940 ▼-100.0%00.0%MedicalWVEWave Life Sciences$0$998,000 ▼-100.0%00.0%MedicalRAPTRAPT Therapeutics$0$915,000 ▼-100.0%00.0%MedicalARWRArrowhead Pharmaceuticals$0$909,650 ▼-100.0%00.0%MedicalSAGIMET BIOSCIENCES INC$0$769,500 ▼-100.0%00.0%COM SER AITCIIntra-Cellular Therapies$0$684,900 ▼-100.0%00.0%MedicalMGNXMacroGenics$0$637,500 ▼-100.0%00.0%MedicalPMVPPMV Pharmaceuticals$0$607,500 ▼-100.0%00.0%MedicalPTCTPTC Therapeutics$0$581,020 ▼-100.0%00.0%MedicalRVNCRevance Therapeutics$0$578,250 ▼-100.0%00.0%MedicalNTLAIntellia Therapeutics$0$559,500 ▼-100.0%00.0%MedicalANTX(ANTX)$0$471,562 ▼-100.0%00.0%MedicalCTMXCytomX Therapeutics$0$366,000 ▼-100.0%00.0%MedicalShowing largest 100 holdings. 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