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Mpm Bioimpact LLC Top Holdings and 13F Report (2025)

About Mpm Bioimpact LLC

Investment Activity

  • Mpm Bioimpact LLC has $704.36 million in total holdings as of December 31, 2024.
  • Mpm Bioimpact LLC owns shares of 47 different stocks, but just 27 companies or ETFs make up 80% of its holdings.
  • Approximately 28.32% of the portfolio was purchased this quarter.
  • About 10.00% of the portfolio was sold this quarter.
  • This quarter, Mpm Bioimpact LLC has purchased 43 new stocks and bought additional shares in 21 stocks.
  • Mpm Bioimpact LLC sold shares of 11 stocks and completely divested from 7 stocks this quarter.

Largest Holdings

Insmed
$26,898,743
Natera
$25,427,096

Largest New Holdings this Quarter

Zai Lab
$20,952,000 Holding
Scholar Rock
$17,985,744 Holding
Context Therapeutics
$15,441,176 Holding
Replimune Group
$11,504,500 Holding
Nuvation Bio
$11,076,713 Holding

Largest Purchases this Quarter

Zai Lab
800,000 shares (about $20.95M)
Scholar Rock
416,144 shares (about $17.99M)
PTC Therapeutics
345,052 shares (about $15.58M)
Context Therapeutics
14,705,882 shares (about $15.44M)
Replimune Group
950,000 shares (about $11.50M)

Largest Sales this Quarter

Insmed
225,780 shares (about $15.59M)
Natera
16,473 shares (about $2.61M)
MoonLake Immunotherapeutics
33,833 shares (about $1.83M)
ALX Oncology
1,018,428 shares (about $1.70M)
Guardant Health
46,431 shares (about $1.42M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofMpm Bioimpact LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
Cullinan Therapeutics, Inc. stock logo
CGEM
Cullinan Therapeutics
$93,155,9040.0%7,648,26813.2%Medical
Crinetics Pharmaceuticals, Inc. stock logo
CRNX
Crinetics Pharmaceuticals
$31,549,000$4,662,545 17.3%617,0354.5%Medical
Edgewise Therapeutics, Inc. stock logo
EWTX
Edgewise Therapeutics
$28,817,737$4,329,405 17.7%1,079,3164.1%Medical
Insmed Incorporated stock logo
INSM
Insmed
$26,898,743$15,587,851 -36.7%389,6113.8%Medical
Natera, Inc. stock logo
NTRA
Natera
$25,427,096$2,607,676 -9.3%160,6263.6%Medical
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
$24,379,092$4,004,996 19.7%589,5793.5%Medical
Disc Medicine, Inc. stock logo
IRON
Disc Medicine
$21,961,823$2,196,176 11.1%346,4013.1%Medical
Lantheus Holdings, Inc. stock logo
LNTH
Lantheus
$21,131,615$7,696,333 57.3%236,2133.0%Medical
Zai Lab Limited stock logo
ZLAB
Zai Lab
$20,952,000$20,952,000 New Holding800,0003.0%Medical
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
$20,442,687$407,294 2.0%702,9812.9%Medical
Iovance Biotherapeutics, Inc. stock logo
IOVA
Iovance Biotherapeutics
$19,786,897$1,977,213 11.1%2,673,9052.8%Medical
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
$19,625,382$15,575,647 384.6%434,7672.8%Medical
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
$18,421,862$10,697,156 138.5%1,489,2372.6%Medical
Scholar Rock Holding Co. stock logo
SRRK
Scholar Rock
$17,985,744$17,985,744 New Holding416,1442.6%Medical
MoonLake Immunotherapeutics stock logo
MLTX
MoonLake Immunotherapeutics
$17,069,705$1,832,057 -9.7%315,2302.4%Medical
Olema Pharmaceuticals, Inc. stock logo
OLMA
Olema Pharmaceuticals
$16,980,167$1,352,292 8.7%2,912,5502.4%Medical
Ultragenyx Pharmaceutical Inc. stock logo
RARE
Ultragenyx Pharmaceutical
$16,450,127$2,578,260 18.6%391,0182.3%Medical
Context Therapeutics Inc. stock logo
CNTX
Context Therapeutics
$15,441,176$15,441,176 New Holding14,705,8822.2%Medical
Guardant Health, Inc. stock logo
GH
Guardant Health
$13,831,176$1,418,467 -9.3%452,7392.0%Medical
Revolution Medicines, Inc. stock logo
RVMD
Revolution Medicines
$13,726,356$980,913 7.7%313,8171.9%Medical
iTeos Therapeutics, Inc. stock logo
ITOS
iTeos Therapeutics
$13,408,8420.0%1,745,9431.9%Medical
Cartesian Therapeutics Inc
$12,915,599$1,642,633 14.6%721,1391.8%Common
Rocket Pharmaceuticals, Inc. stock logo
RCKT
Rocket Pharmaceuticals
$12,828,427$575,882 -4.3%1,020,5591.8%Medical
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
$12,814,365$1,893,791 17.3%460,6171.8%Medical
Trevi Therapeutics, Inc. stock logo
TRVI
Trevi Therapeutics
$12,750,972$6,412,282 101.2%3,094,8961.8%Medical
Twist Bioscience Co. stock logo
TWST
Twist Bioscience
$12,430,586$1,274,812 -9.3%267,4971.8%Medical
Compass Therapeutics, Inc. stock logo
CMPX
Compass Therapeutics
$12,423,449$4,242,703 51.9%8,567,8961.8%Medical
Janux Therapeutics, Inc. stock logo
JANX
Janux Therapeutics
$12,314,200$3,153,238 34.4%230,0001.7%Medical
Replimune Group, Inc. stock logo
REPL
Replimune Group
$11,504,500$11,504,500 New Holding950,0001.6%Medical
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
$11,076,713$11,076,713 New Holding4,164,1781.6%Medical
Vera Therapeutics, Inc. stock logo
VERA
Vera Therapeutics
$10,901,855$10,901,855 New Holding257,7881.5%Medical
IDEAYA Biosciences, Inc. stock logo
IDYA
IDEAYA Biosciences
$10,640,700$10,640,700 New Holding414,0351.5%Medical
Relay Therapeutics, Inc. stock logo
RLAY
Relay Therapeutics
$9,347,559$971,430 11.6%2,268,8251.3%Medical
United Therapeutics Co. stock logo
UTHR
United Therapeutics
$8,115,320$8,115,320 New Holding23,0001.2%Medical
Arcturus Therapeutics Holdings Inc. stock logo
ARCT
Arcturus Therapeutics
$7,805,233$4,080,182 109.5%459,9431.1%Medical
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
$7,730,710$1,231,350 18.9%197,2121.1%Medical
Stoke Therapeutics, Inc. stock logo
STOK
Stoke Therapeutics
$7,564,661$2,276,305 43.0%685,8261.1%Medical
Aquestive Therapeutics, Inc. stock logo
AQST
Aquestive Therapeutics
$5,738,125$658,304 -10.3%1,611,8330.8%Medical
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
$4,230,500$4,230,500 New Holding50,0000.6%Medical
Sutro Biopharma, Inc. stock logo
STRO
Sutro Biopharma
$3,974,514$1,236,484 -23.7%2,160,0620.6%Medical
Werewolf Therapeutics, Inc. stock logo
HOWL
Werewolf Therapeutics
$3,534,2560.0%2,388,0110.5%Medical
Design Therapeutics, Inc. stock logo
DSGN
Design Therapeutics
$3,452,405$3,452,405 New Holding559,5470.5%Medical
Zentalis Pharmaceuticals, Inc. stock logo
ZNTL
Zentalis Pharmaceuticals
$3,353,759$1,087,619 -24.5%1,106,8510.5%Medical
Veru Inc. stock logo
VERU
Veru
$2,787,630$2,787,630 New Holding4,285,3650.4%Medical
Adaptimmune Therapeutics plc stock logo
ADAP
Adaptimmune Therapeutics
$2,746,6970.0%5,095,9120.4%Medical
ALX Oncology Holdings Inc. stock logo
ALXO
ALX Oncology
$2,323,695$1,700,775 -42.3%1,391,4340.3%Medical
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
$1,612,812$535,391 -24.9%1,231,1540.2%Medical
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
$0$15,363,667 -100.0%00.0%Medical
KalVista Pharmaceuticals, Inc. stock logo
KALV
KalVista Pharmaceuticals
$0$10,386,276 -100.0%00.0%Medical
Viking Therapeutics, Inc. stock logo
VKTX
Viking Therapeutics
$0$7,659,370 -100.0%00.0%Medical
Intellia Therapeutics, Inc. stock logo
NTLA
Intellia Therapeutics
$0$5,498,296 -100.0%00.0%Medical
89bio, Inc. stock logo
ETNB
89bio
$0$2,442,000 -100.0%00.0%Medical
REGENXBIO Inc. stock logo
RGNX
REGENXBIO
$0$524,500 -100.0%00.0%Medical
Solid Biosciences Inc. stock logo
SLDB
Solid Biosciences
$0$80,280 -100.0%00.0%Medical

Showing largest 100 holdings. View all holdings.
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