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Octagon Capital Advisors Lp Top Holdings and 13F Report (2025)

About Octagon Capital Advisors Lp

Investment Activity

  • Octagon Capital Advisors Lp has $607.70 million in total holdings as of December 31, 2024.
  • Octagon Capital Advisors Lp owns shares of 31 different stocks, but just 16 companies or ETFs make up 80% of its holdings.
  • Approximately 23.81% of the portfolio was purchased this quarter.
  • About 31.66% of the portfolio was sold this quarter.
  • This quarter, Octagon Capital Advisors Lp has purchased 41 new stocks and bought additional shares in 12 stocks.
  • Octagon Capital Advisors Lp sold shares of 4 stocks and completely divested from 17 stocks this quarter.

Largest Holdings

ARRIVENT BIOPHARMA INC
$54,862,070
DIANTHUS THERAPEUTICS INC
$46,001,641
Insmed
$40,181,280

Largest New Holdings this Quarter

Scholar Rock
$21,091,360 Holding
Merus
$12,951,400 Holding
Erasca
$12,893,355 Holding
Syndax Pharmaceuticals
$11,950,880 Holding
KalVista Pharmaceuticals
$11,603,900 Holding

Largest Purchases this Quarter

Scholar Rock
488,000 shares (about $21.09M)
Merus
308,000 shares (about $12.95M)
Erasca
5,136,795 shares (about $12.89M)
Syndax Pharmaceuticals
904,000 shares (about $11.95M)
KalVista Pharmaceuticals
1,370,000 shares (about $11.60M)

Largest Sales this Quarter

Verona Pharma
1,263,936 shares (about $58.70M)
Nuvation Bio
2,968,606 shares (about $7.90M)
Insmed
104,820 shares (about $7.24M)
BridgeBio Pharma
110,400 shares (about $3.03M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofOctagon Capital Advisors Lp

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
$95,952,7320.0%3,006,98015.8%Medical
ARRIVENT BIOPHARMA INC
$54,862,070$2,211,120 4.2%2,059,3879.0%COM
DIANTHUS THERAPEUTICS INC
$46,001,641$7,924,300 20.8%2,110,1677.6%COM
Insmed Incorporated stock logo
INSM
Insmed
$40,181,280$7,236,773 -15.3%582,0006.6%Medical
Centessa Pharmaceuticals plc stock logo
CNTA
Centessa Pharmaceuticals
$35,929,621$2,227,750 6.6%2,145,0525.9%Medical
Verona Pharma plc stock logo
VRNA
Verona Pharma
$26,529,500$58,697,187 -68.9%571,2644.4%Medical
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
$24,479,733$7,896,492 -24.4%9,202,9074.0%Medical
Cogent Biosciences, Inc. stock logo
COGT
Cogent Biosciences
$21,551,400$11,372,400 111.7%2,763,0003.5%Medical
Scholar Rock Holding Co. stock logo
SRRK
Scholar Rock
$21,091,360$21,091,360 New Holding488,0003.5%Medical
Mind Medicine (MindMed) Inc. stock logo
MNMD
Mind Medicine (MindMed)
$21,005,2800.0%3,018,0003.5%Medical
Ocular Therapeutix, Inc. stock logo
OCUL
Ocular Therapeutix
$20,709,5000.0%2,425,0003.4%Medical
Taysha Gene Therapies, Inc. stock logo
TSHA
Taysha Gene Therapies
$18,078,500$10,168,556 128.6%10,450,0003.0%Medical
Viridian Therapeutics, Inc. stock logo
VRDN
Viridian Therapeutics
$16,677,9000.0%870,0002.7%Medical
Gossamer Bio, Inc. stock logo
GOSS
Gossamer Bio
$16,599,410$8,288,051 99.7%18,350,0002.7%Medical
DYNE THERAPEUTICS INC
$15,738,080$9,548,255 154.3%668,0002.6%COM
Pharvaris stock logo
PHVS
Pharvaris
$14,914,260$3,019,850 25.4%778,0002.5%Medical
Corbus Pharmaceuticals Holdings, Inc. stock logo
CRBP
Corbus Pharmaceuticals
$13,157,0000.0%1,115,0002.2%Medical
Merus stock logo
MRUS
Merus
$12,951,400$12,951,400 New Holding308,0002.1%Medical
Erasca, Inc. stock logo
ERAS
Erasca
$12,893,355$12,893,355 New Holding5,136,7952.1%Medical
BridgeBio Pharma, Inc. stock logo
BBIO
BridgeBio Pharma
$12,117,504$3,029,376 -20.0%441,6002.0%Medical
Syndax Pharmaceuticals, Inc. stock logo
SNDX
Syndax Pharmaceuticals
$11,950,880$11,950,880 New Holding904,0002.0%Medical
KalVista Pharmaceuticals, Inc. stock logo
KALV
KalVista Pharmaceuticals
$11,603,900$11,603,900 New Holding1,370,0001.9%Medical
Unicycive Therapeutics, Inc. stock logo
UNCY
Unicycive Therapeutics
$7,942,000$1,144,442 16.8%10,000,0001.3%Medical
Regulus Therapeutics Inc. stock logo
RGLS
Regulus Therapeutics
$7,661,107$924,460 13.7%4,848,8021.3%Medical
PERSPECTIVE THERAPEUTICS INC
$7,352,159$2,815,264 62.1%2,304,7521.2%COM NEW
NEUROGENE INC
$6,926,580$6,583,680 1,920.0%303,0001.1%COM
ALLOVIR INC
$4,710,300$4,710,300 New Holding11,215,0000.8%COM
aTyr Pharma, Inc. stock logo
LIFE
aTyr Pharma
$3,258,000$3,258,000 New Holding900,0000.5%Medical
HELIX ACQUISITION CORP II
$2,625,0000.0%250,0000.4%CL A ORD SHS
Mersana Therapeutics, Inc. stock logo
MRSN
Mersana Therapeutics
$1,418,5600.0%992,0000.2%Medical
NUVATION BIO INC
$830,8140.0%312,3360.1%*W EXP 02/10/202
Structure Therapeutics Inc. stock logo
GPCR
Structure Therapeutics
$0$52,580,220 -100.0%00.0%Medical
AlloVir, Inc. stock logo
ALVR
AlloVir
$0$9,056,817 -100.0%00.0%Medical
EyePoint Pharmaceuticals, Inc. stock logo
EYPT
EyePoint Pharmaceuticals
$0$8,737,089 -100.0%00.0%Medical
PRAXIS PRECISION MEDICINES I
$0$7,480,200 -100.0%00.0%COM NEW
Mineralys Therapeutics, Inc. stock logo
MLYS
Mineralys Therapeutics
$0$7,266,000 -100.0%00.0%Medical
Ventyx Biosciences, Inc. stock logo
VTYX
Ventyx Biosciences
$0$5,212,629 -100.0%00.0%Medical
Tenaya Therapeutics, Inc. stock logo
TNYA
Tenaya Therapeutics
$0$4,972,066 -100.0%00.0%Medical
CYBIN INC
$0$4,352,508 -100.0%00.0%COM
Reneo Pharmaceuticals, Inc. stock logo
RPHM
Reneo Pharmaceuticals
$0$3,825,000 -100.0%00.0%Medical
PepGen Inc. stock logo
PEPG
PepGen
$0$3,215,800 -100.0%00.0%Medical
Black Diamond Therapeutics, Inc. stock logo
BDTX
Black Diamond Therapeutics
$0$2,583,900 -100.0%00.0%Medical
Annexon, Inc. stock logo
ANNX
Annexon
$0$2,368,000 -100.0%00.0%Medical
Century Therapeutics, Inc. stock logo
IPSC
Century Therapeutics
$0$1,140,271 -100.0%00.0%Medical
Aerovate Therapeutics, Inc. stock logo
AVTE
Aerovate Therapeutics
$0$972,770 -100.0%00.0%Medical
Autolus Therapeutics plc stock logo
AUTL
Autolus Therapeutics
$0$638,880 -100.0%00.0%Medical
RAPT Therapeutics, Inc. stock logo
RAPT
RAPT Therapeutics
$0$586,920 -100.0%00.0%Medical
Nkarta, Inc. stock logo
NKTX
Nkarta
$0$542,400 -100.0%00.0%Medical

Showing largest 100 holdings. View all holdings.
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