Opaleye Management Inc. Top Holdings and 13F Report (2024) About Opaleye Management Inc.Investment ActivityOpaleye Management Inc. has $599.56 million in total holdings as of September 30, 2024.Opaleye Management Inc. owns shares of 44 different stocks, but just 14 companies or ETFs make up 80% of its holdings.Approximately 12.16% of the portfolio was purchased this quarter.About 11.16% of the portfolio was sold this quarter.This quarter, Opaleye Management Inc. has purchased 51 new stocks and bought additional shares in 11 stocks.Opaleye Management Inc. sold shares of 18 stocks and completely divested from 13 stocks this quarter.Largest Holdings Harrow $179,390,400TG Therapeutics $53,329,200Ocular Therapeutix $43,717,500Arvinas $30,910,650Codexis $27,011,600 Largest New Holdings this Quarter GINKGO BIOWORKS HOLDINGS $6,684,646 HoldingZentalis Pharmaceuticals $3,558,560 HoldingRezolute $2,262,831 HoldingPepGen $1,532,331 HoldingRevance Therapeutics $1,427,250 Holding Largest Purchases this Quarter Arvinas 700,000 shares (about $17.24M)Codexis 5,315,000 shares (about $16.37M)Liquidia 1,373,142 shares (about $13.73M)GINKGO BIOWORKS HOLDINGS 820,202 shares (about $6.68M)Zentalis Pharmaceuticals 967,000 shares (about $3.56M) Largest Sales this Quarter Catalyst Pharmaceuticals 527,500 shares (about $10.49M)Cytokinetics 123,200 shares (about $6.50M)Applied Therapeutics 360,000 shares (about $3.06M)Ocular Therapeutix 282,500 shares (about $2.46M)Edgewise Therapeutics 57,500 shares (about $1.53M) Sector Allocation Over TimeMap of 500 Largest Holdings ofOpaleye Management Inc. Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorHROWHarrow$179,390,4000.0%3,990,00029.9%MedicalTGTXTG Therapeutics$53,329,2000.0%2,280,0008.9%MedicalOCULOcular Therapeutix$43,717,500$2,457,750 ▼-5.3%5,025,0007.3%MedicalARVNArvinas$30,910,650$17,241,000 ▲126.1%1,255,0005.2%MedicalCDXSCodexis$27,011,600$16,370,200 ▲153.8%8,770,0004.5%MedicalRYTMRhythm Pharmaceuticals$26,195,000$785,850 ▼-2.9%500,0004.4%MedicalKROSKeros Therapeutics$22,953,677$1,612,952 ▲7.6%395,2763.8%MedicalIMNMImmunome$18,092,250$1,973,700 ▲12.2%1,237,5003.0%MedicalLQDALiquidia$16,981,420$13,731,420 ▲422.5%1,698,1422.8%MedicalETONEton Pharmaceuticals$16,680,000$2,310,000 ▲16.1%2,780,0002.8%MedicalEWTXEdgewise Therapeutics$13,945,525$1,534,675 ▼-9.9%522,5002.3%MedicalCARGO THERAPEUTICS INC$11,834,513$311,755 ▼-2.6%541,4372.0%COMAPLTApplied Therapeutics$11,220,000$3,060,000 ▼-21.4%1,320,0001.9%MedicalPCVXVaxcyte$9,712,9500.0%85,0001.6%MedicalNRIXNurix Therapeutics$9,437,400$24,088 ▲0.3%420,0001.6%MedicalSLRNAcelyrin$9,335,744$1,546,344 ▲19.9%1,893,6601.6%MedicalTRVITrevi Therapeutics$8,577,087$257,213 ▼-2.9%2,567,9901.4%MedicalBDSXBiodesix$6,970,700$374,572 ▼-5.1%3,815,0001.2%MedicalGINKGO BIOWORKS HOLDINGS$6,684,646$6,684,646 ▲New Holding820,2021.1%Class A NewJASPER THERAPEUTICS INC$6,649,335$724,185 ▼-9.8%353,5001.1%COM NEWXOMAXOMA$6,620,0000.0%250,0001.1%MedicalNUVLNuvalent$6,547,200$480,810 ▲7.9%64,0001.1%MedicalNAMSNewAmsterdam Pharma$5,561,000$332,000 ▲6.3%335,0000.9%MedicalURGNUroGen Pharma$5,132,070$100,330 ▼-1.9%404,1000.9%MedicalPTGXProtagonist Therapeutics$4,725,0000.0%105,0000.8%MedicalGOSSAMER BIO INC$4,188,9280.0%8,000,0000.7%NOTE 5.000% 6/0CYTKCytokinetics$3,975,840$6,504,960 ▼-62.1%75,3000.7%MedicalKARYOPHARM THERAPEUTICS INC$3,960,6720.0%6,000,0000.7%NOTE 3.000%10/1GOSSGossamer Bio$3,705,692$247,709 ▼-6.3%3,665,0100.6%MedicalZNTLZentalis Pharmaceuticals$3,558,560$3,558,560 ▲New Holding967,0000.6%MedicalTARAProtara Therapeutics$3,076,512$1,140,288 ▼-27.0%1,681,1540.5%MedicalRZLTRezolute$2,262,831$2,262,831 ▲New Holding466,5630.4%MedicalCPRXCatalyst Pharmaceuticals$2,236,500$10,486,700 ▼-82.4%112,5000.4%MedicalABCLAbCellera Biologics$2,080,000$1,560,000 ▲300.0%800,0000.3%MedicalLYELLyell Immunopharma$1,925,100$379,500 ▼-16.5%1,395,0000.3%MedicalALLKAllakos$1,572,644$243,252 ▼-13.4%2,407,6000.3%MedicalRLMDRelmada Therapeutics$1,555,200$388,800 ▼-20.0%480,0000.3%MedicalPEPGPepGen$1,532,331$1,532,331 ▲New Holding179,2000.3%MedicalRVNCRevance Therapeutics$1,427,250$1,427,250 ▲New Holding275,0000.2%MedicalSYRSSyros Pharmaceuticals$1,408,127$452,575 ▼-24.3%654,9430.2%MedicalAVTEAerovate Therapeutics$919,6000.0%440,0000.2%MedicalRGLSRegulus Therapeutics$839,950$1,475,800 ▼-63.7%535,0000.1%MedicalIBIO INC$832,5000.0%375,0000.1%COM NEWADAGIO MED HLDGS INC$285,273$285,273 ▲New Holding110,5710.0%COMFDMT4D Molecular Therapeutics$0$7,257,293 ▼-100.0%00.0%MedicalIOVAIovance Biotherapeutics$0$7,193,940 ▼-100.0%00.0%MedicalNTLAIntellia Therapeutics$0$4,878,840 ▼-100.0%00.0%MedicalLXRXLexicon Pharmaceuticals$0$3,150,000 ▼-100.0%00.0%MedicalSVRASavara$0$2,881,289 ▼-100.0%00.0%MedicalVTYXVentyx Biosciences$0$2,748,900 ▼-100.0%00.0%MedicalVSTMVerastem$0$2,726,700 ▼-100.0%00.0%MedicalFULCFulcrum Therapeutics$0$1,767,000 ▼-100.0%00.0%MedicalKPTIKaryopharm Therapeutics$0$1,236,330 ▼-100.0%00.0%MedicalPMVPPMV Pharmaceuticals$0$769,500 ▼-100.0%00.0%MedicalDSGNDesign Therapeutics$0$686,750 ▼-100.0%00.0%MedicalALGSAligos Therapeutics$0$441,000 ▼-100.0%00.0%MedicalRPHMReneo Pharmaceuticals$0$249,150 ▼-100.0%00.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. Real-time analyst ratings, insider transactions, earnings data, and more. Our daily ratings and market update email newsletter. Sign in to your free account to enjoy all that MarketBeat has to offer. Sign In Create Account Your Email Address: Email Address Required Your Password: Password Required Log In or Sign in with Facebook Sign in with Google Forgot your password? Your Email Address: Please enter your email address. Please enter a valid email address Choose a Password: Please enter your password. Your password must be at least 8 characters long and contain at least 1 number, 1 letter, and 1 special character. Create My Account (Free) or Sign in with Facebook Sign in with Google By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
