Paradigm Biocapital Advisors Lp Top Holdings and 13F Report (2024) About Paradigm Biocapital Advisors LpInvestment ActivityParadigm Biocapital Advisors Lp has $2.96 billion in total holdings as of September 30, 2024.Paradigm Biocapital Advisors Lp owns shares of 31 different stocks, but just 15 companies or ETFs make up 80% of its holdings.Approximately 18.73% of the portfolio was purchased this quarter.About 22.38% of the portfolio was sold this quarter.This quarter, Paradigm Biocapital Advisors Lp has purchased 35 new stocks and bought additional shares in 15 stocks.Paradigm Biocapital Advisors Lp sold shares of 7 stocks and completely divested from 11 stocks this quarter.Largest Holdings Nuvalent $511,500,000Arcellx $400,848,000argenx $260,401,138Revolution Medicines $240,993,936Crinetics Pharmaceuticals $128,602,655 Largest New Holdings this Quarter Vera Therapeutics $48,480,814 HoldingMoonLake Immunotherapeutics $46,965,222 HoldingBeiGene $44,977,435 HoldingSPYRE THERAPEUTICS INC $37,279,557 HoldingPliant Therapeutics $34,801,288 Holding Largest Purchases this Quarter Arcellx 951,905 shares (about $79.49M)Vera Therapeutics 1,096,851 shares (about $48.48M)MoonLake Immunotherapeutics 931,480 shares (about $46.97M)BeiGene 200,336 shares (about $44.98M)Nuvalent 428,322 shares (about $43.82M) Largest Sales this Quarter Disc Medicine 1,206,998 shares (about $59.31M)argenx 57,765 shares (about $31.31M)Olema Pharmaceuticals 2,400,000 shares (about $28.66M)COMPASS Pathways 1,175,926 shares (about $7.41M)Kura Oncology 208,060 shares (about $4.07M) Sector Allocation Over TimeMap of 500 Largest Holdings ofParadigm Biocapital Advisors Lp Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorNUVLNuvalent$511,500,000$43,817,341 ▲9.4%5,000,00017.3%MedicalACLXArcellx$400,848,000$79,493,587 ▲24.7%4,800,00013.6%MedicalARGXargenx$260,401,138$31,313,251 ▼-10.7%480,3748.8%MedicalRVMDRevolution Medicines$240,993,936$2,494,250 ▲1.0%5,314,0898.2%MedicalCRNXCrinetics Pharmaceuticals$128,602,655$172,922 ▲0.1%2,516,6864.4%MedicalMRUSMerus$122,647,653$21,737,746 ▲21.5%2,454,9174.1%MedicalJANXJanux Therapeutics$109,058,077$37,985,023 ▲53.4%2,400,5743.7%MedicalPCVXVaxcyte$103,360,872$31,690,499 ▲44.2%904,5323.5%MedicalKURAKura Oncology$84,634,012$4,065,492 ▼-4.6%4,331,3212.9%MedicalTARSTarsus Pharmaceuticals$80,266,236$165,404 ▲0.2%2,440,4452.7%MedicalEWTXEdgewise Therapeutics$74,443,001$12,376,767 ▲19.9%2,789,1722.5%MedicalIRONDisc Medicine$73,597,961$59,311,882 ▼-44.6%1,497,7202.5%MedicalVRDNViridian Therapeutics$65,876,925$15,015 ▼0.0%2,895,6892.2%MedicalOLMAOlema Pharmaceuticals$65,712,984$28,656,000 ▼-30.4%5,503,6002.2%MedicalARVNArvinas$57,633,239$2,418,370 ▼-4.0%2,339,9611.9%MedicalYMABY-mAbs Therapeutics$53,735,450$2,837,139 ▲5.6%4,086,3461.8%MedicalCOGTCogent Biosciences$49,785,430$10,642,536 ▲27.2%4,609,7621.7%MedicalVERAVera Therapeutics$48,480,814$48,480,814 ▲New Holding1,096,8511.6%MedicalMLTXMoonLake Immunotherapeutics$46,965,222$46,965,222 ▲New Holding931,4801.6%MedicalBGNEBeiGene$44,977,435$44,977,435 ▲New Holding200,3361.5%MedicalIMTXImmatics$44,554,475$5,509,855 ▲14.1%3,904,8621.5%MedicalAPOGEE THERAPEUTICS INC$41,224,731$21,840,531 ▲112.7%701,8171.4%COMIMVTImmunovant$38,854,1980.0%1,362,8271.3%MedicalCGEMCullinan Therapeutics$38,853,758$13,027,202 ▲50.4%2,321,0131.3%MedicalSPYRE THERAPEUTICS INC$37,279,557$37,279,557 ▲New Holding1,267,5811.3%COM NEWPLRXPliant Therapeutics$34,801,288$34,801,288 ▲New Holding3,104,4861.2%MedicalKROSKeros Therapeutics$30,488,899$30,488,899 ▲New Holding525,0371.0%MedicalERASErasca$29,124,025$9,331,525 ▲47.1%10,668,1411.0%MedicalORUKA THERAPEUTICS INC$17,638,867$17,638,867 ▲New Holding719,6600.6%COMPERSPECTIVE THERAPEUTICS INC$12,277,8880.0%919,6920.4%COM NEWCMPSCOMPASS Pathways$7,308,000$7,408,334 ▼-50.3%1,160,0000.2%MedicalSRPTSarepta Therapeutics$0$149,716,692 ▼-100.0%00.0%MedicalCERECerevel Therapeutics$0$95,294,472 ▼-100.0%00.0%MedicalASNDAscendis Pharma A/S$0$90,598,189 ▼-100.0%00.0%MedicalXENEXenon Pharmaceuticals$0$79,667,487 ▼-100.0%00.0%MedicalLEGNLegend Biotech$0$53,294,511 ▼-100.0%00.0%MedicalBBIOBridgeBio Pharma$0$27,596,832 ▼-100.0%00.0%MedicalVRNAVerona Pharma$0$10,426,918 ▼-100.0%00.0%MedicalALXOALX Oncology$0$9,500,898 ▼-100.0%00.0%MedicalVORVor Biopharma$0$6,457,293 ▼-100.0%00.0%MedicalACRVAcrivon Therapeutics$0$3,826,399 ▼-100.0%00.0%MedicalTCRXTScan Therapeutics$0$2,070,233 ▼-100.0%00.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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