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Perceptive Advisors LLC Top Holdings and 13F Report (2024)

About Perceptive Advisors LLC

Investment Activity

  • Perceptive Advisors LLC has $4.73 billion in total holdings as of September 30, 2024.
  • Perceptive Advisors LLC owns shares of 106 different stocks, but just 34 companies or ETFs make up 80% of its holdings.
  • Approximately 15.80% of the portfolio was purchased this quarter.
  • About 18.94% of the portfolio was sold this quarter.
  • This quarter, Perceptive Advisors LLC has purchased 109 new stocks and bought additional shares in 24 stocks.
  • Perceptive Advisors LLC sold shares of 24 stocks and completely divested from 18 stocks this quarter.

Largest Holdings

Arcellx
$324,742,748
Nuvalent
$304,775,741
Amicus Therapeutics
$299,653,630
Vaxcyte
$231,694,766

Largest New Holdings this Quarter

Insulet
$33,113,110 Holding
ORUKA THERAPEUTICS INC
$30,274,433 Holding
DYNE THERAPEUTICS INC
$25,795,732 Holding
ADAGIO MED HLDGS INC
$25,316,041 Holding
INSTIL BIO INC
$23,262,089 Holding

Largest Purchases this Quarter

Verona Pharma
4,382,208 shares (about $126.08M)
Viking Therapeutics
978,610 shares (about $61.96M)
argenx
103,239 shares (about $55.96M)
Nuvalent
430,158 shares (about $44.01M)
Centessa Pharmaceuticals
2,348,983 shares (about $37.56M)

Largest Sales this Quarter

Neurocrine Biosciences
437,681 shares (about $50.43M)
Natera
310,000 shares (about $39.35M)
Crinetics Pharmaceuticals
751,505 shares (about $38.40M)
ADMA Biologics
1,710,800 shares (about $34.20M)
SpringWorks Therapeutics
960,699 shares (about $30.78M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofPerceptive Advisors LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
Arcellx, Inc. stock logo
ACLX
Arcellx
$324,742,748$89,356 0.0%3,888,6696.9%Medical
Nuvalent, Inc. stock logo
NUVL
Nuvalent
$304,775,741$44,005,163 16.9%2,979,2356.4%Medical
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
$299,653,6300.0%28,057,4566.3%Medical
Iovance Biotherapeutics, Inc. stock logo
IOVA
Iovance Biotherapeutics
$249,940,287$6,428,084 2.6%26,617,7095.3%Medical
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$231,694,766$18,854,550 8.9%2,027,6084.9%Medical
Verona Pharma plc stock logo
VRNA
Verona Pharma
$196,094,392$126,076,124 180.1%6,815,9334.1%Medical
Rhythm Pharmaceuticals, Inc. stock logo
RYTM
Rhythm Pharmaceuticals
$186,519,611$5,953,338 3.3%3,560,2143.9%Medical
Soleno Therapeutics, Inc. stock logo
SLNO
Soleno Therapeutics
$161,819,2380.0%3,204,9763.4%Medical
Intra-Cellular Therapies, Inc. stock logo
ITCI
Intra-Cellular Therapies
$118,697,472$6,892,029 -5.5%1,622,2152.5%Medical
APOGEE THERAPEUTICS INC
$118,361,511$5,323,547 -4.3%2,015,0072.5%COM
Viking Therapeutics, Inc. stock logo
VKTX
Viking Therapeutics
$107,626,177$61,955,799 135.7%1,699,9872.3%Medical
Centessa Pharmaceuticals plc stock logo
CNTA
Centessa Pharmaceuticals
$100,453,817$37,560,238 59.7%6,282,2902.1%Medical
Immatics stock logo
IMTX
Immatics
$92,263,0740.0%8,086,1592.0%Medical
Evolus, Inc. stock logo
EOLS
Evolus
$86,777,276$6,434,251 -6.9%5,356,6221.8%Medical
SPYRE THERAPEUTICS INC
$84,481,607$4,660,632 -5.2%2,872,5471.8%COM NEW
Artivion, Inc. stock logo
AORT
Artivion
$74,368,3740.0%2,793,7031.6%Medical
Biohaven Ltd. stock logo
BHVN
Biohaven
$74,217,0430.0%1,485,2321.6%Medical
Astria Therapeutics, Inc. stock logo
ATXS
Astria Therapeutics
$71,404,4740.0%6,485,4201.5%Medical
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
$70,354,190$29,093,885 70.5%782,8441.5%Medical
Applied Therapeutics, Inc. stock logo
APLT
Applied Therapeutics
$68,042,5000.0%8,005,0001.4%Medical
CARGO THERAPEUTICS INC
$67,951,4230.0%3,683,0041.4%COM
Immunovant, Inc. stock logo
IMVT
Immunovant
$67,818,505$7,269,366 12.0%2,378,7621.4%Medical
PRAXIS PRECISION MEDICINES I
$66,978,574$23,810,340 55.2%1,164,0351.4%COM NEW
argenx SE stock logo
ARGX
argenx
$64,420,245$55,963,797 661.8%118,8391.4%Medical
Viridian Therapeutics, Inc. stock logo
VRDN
Viridian Therapeutics
$63,988,129$26,864,042 72.4%2,812,6651.4%Medical
Edgewise Therapeutics, Inc. stock logo
EWTX
Edgewise Therapeutics
$62,195,547$12,647,777 25.5%2,330,2941.3%Medical
Protagonist Therapeutics, Inc. stock logo
PTGX
Protagonist Therapeutics
$61,855,335$4,762,260 8.3%1,374,5631.3%Medical
MeiraGTx Holdings plc stock logo
MGTX
MeiraGTx
$52,430,095$5,209,211 11.0%12,581,1031.1%Medical
Aldeyra Therapeutics, Inc stock logo
ALDX
Aldeyra Therapeutics
$49,996,8370.0%9,275,8511.1%Medical
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
$49,197,784$6,165,739 14.3%1,714,8061.0%Medical
Solid Biosciences Inc. stock logo
SLDB
Solid Biosciences
$48,139,3220.0%6,906,6461.0%Medical
Tarsus Pharmaceuticals, Inc. stock logo
TARS
Tarsus Pharmaceuticals
$42,639,1220.0%1,296,4160.9%Medical
SPDR S&P Biotech ETF stock logo
XBI
SPDR S&P Biotech ETF
$39,520,000$37,280,698 1,664.8%400,0000.8%ETF
Acrivon Therapeutics, Inc. stock logo
ACRV
Acrivon Therapeutics
$37,526,0060.0%5,360,8580.8%Medical
Crinetics Pharmaceuticals, Inc. stock logo
CRNX
Crinetics Pharmaceuticals
$37,032,068$38,401,906 -50.9%724,6980.8%Medical
Nautilus Biotechnology, Inc. stock logo
NAUT
Nautilus Biotechnology
$35,893,5010.0%12,594,2110.8%Medical
Celcuity Inc. stock logo
CELC
Celcuity
$35,221,5800.0%2,362,2790.7%Medical
Insulet Co. stock logo
PODD
Insulet
$33,113,110$33,113,110 New Holding142,2690.7%Medical
ORUKA THERAPEUTICS INC
$30,274,433$30,274,433 New Holding1,235,1870.6%COM
CONTINEUM THERAPEUTICS INC
$29,029,026$957,000 -3.2%1,516,6680.6%CL A
Ocular Therapeutix, Inc. stock logo
OCUL
Ocular Therapeutix
$28,922,8720.0%3,324,4680.6%Medical
Intuitive Surgical, Inc. stock logo
ISRG
Intuitive Surgical
$28,552,121$1,808,365 -6.0%58,1190.6%Medical
Natera, Inc. stock logo
NTRA
Natera
$27,929,000$39,354,500 -58.5%220,0000.6%Medical
CG ONCOLOGY INC
$27,682,3120.0%733,6950.6%COM
Zymeworks Inc. stock logo
ZYME
Zymeworks
$27,359,251$6,429,478 30.7%2,180,0200.6%Medical
DYNE THERAPEUTICS INC
$25,795,732$25,795,732 New Holding718,1440.5%COM
ADAGIO MED HLDGS INC
$25,316,041$25,316,041 New Holding9,812,4190.5%COM
Arvinas, Inc. stock logo
ARVN
Arvinas
$25,313,4580.0%1,027,7490.5%Medical
PROCEPT BioRobotics Co. stock logo
PRCT
PROCEPT BioRobotics
$25,290,599$8,412,600 49.8%315,6590.5%Medical
Neurocrine Biosciences, Inc. stock logo
NBIX
Neurocrine Biosciences
$24,452,910$50,429,604 -67.3%212,2280.5%Medical
Orchestra BioMed Holdings, Inc. stock logo
OBIO
Orchestra BioMed
$23,605,738$10,519,910 80.4%4,592,5560.5%Medical
INSTIL BIO INC
$23,262,089$23,262,089 New Holding345,5450.5%COM NEW
LivaNova PLC stock logo
LIVN
LivaNova
$22,539,660$788,100 -3.4%429,0000.5%Medical
SpringWorks Therapeutics, Inc. stock logo
SWTX
SpringWorks Therapeutics
$22,180,107$30,780,797 -58.1%692,2630.5%Medical
Medtronic plc stock logo
MDT
Medtronic
$22,087,240$22,087,330 -50.0%245,3320.5%Medical
ADMA Biologics, Inc. stock logo
ADMA
ADMA Biologics
$21,193,398$34,198,892 -61.7%1,060,2000.4%Medical
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
$20,666,494$2,296,295 -10.0%524,9300.4%Medical
ZENAS BIOPHARMA INC
$19,357,072$19,357,072 New Holding1,144,0350.4%COM
Disc Medicine, Inc. stock logo
IRON
Disc Medicine
$19,018,015$8,177,879 -30.1%387,0170.4%Medical
Rocket Pharmaceuticals, Inc. stock logo
RCKT
Rocket Pharmaceuticals
$17,211,288$5,813,359 -25.2%931,8510.4%Medical
INHIBRX BIOSCIENCES INC
$16,662,6470.0%1,064,0260.4%COM
RAPPORT THERAPEUTICS INC
$15,322,7880.0%748,1830.3%COM
Merus stock logo
MRUS
Merus
$14,988,0000.0%300,0000.3%Medical
Insmed Incorporated stock logo
INSM
Insmed
$13,140,0000.0%180,0000.3%Medical
ICON Public Limited stock logo
ICLR
ICON Public
$12,743,060$3,764,623 41.9%44,3530.3%Medical
Arcutis Biotherapeutics, Inc. stock logo
ARQT
Arcutis Biotherapeutics
$12,634,050$1,860,000 -12.8%1,358,5000.3%Medical
PepGen Inc. stock logo
PEPG
PepGen
$12,059,2450.0%1,410,4380.3%Medical
Tyra Biosciences, Inc. stock logo
TYRA
Tyra Biosciences
$12,018,923$11,664,275 -49.3%511,2260.3%Medical
Xencor, Inc. stock logo
XNCR
Xencor
$10,611,464$10,611,464 New Holding527,6710.2%Medical
Verrica Pharmaceuticals Inc. stock logo
VRCA
Verrica Pharmaceuticals
$10,293,8140.0%7,099,1820.2%Medical
Roivant Sciences Ltd. stock logo
ROIV
Roivant Sciences
$9,782,977$9,782,977 New Holding847,7450.2%Medical
ARRIVENT BIOPHARMA INC
$9,752,5000.0%415,0000.2%COM
Exact Sciences Co. stock logo
EXAS
Exact Sciences
$8,515,000$8,515,000 New Holding125,0000.2%Medical
EyePoint Pharmaceuticals, Inc. stock logo
EYPT
EyePoint Pharmaceuticals
$8,287,819$3,172,030 62.0%1,037,2740.2%Medical
Allogene Therapeutics, Inc. stock logo
ALLO
Allogene Therapeutics
$7,630,0000.0%2,725,0000.2%Medical
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
$6,887,103$6,887,103 New Holding2,125,6490.1%Medical
Bicycle Therapeutics plc stock logo
BCYC
Bicycle Therapeutics
$5,793,144$7,151,216 -55.2%255,9940.1%Medical
Veru Inc. stock logo
VERU
Veru
$5,600,748$169,088 3.1%7,283,1570.1%Medical
Cassava Sciences, Inc. stock logo
SAVA
Cassava Sciences
$5,385,6900.0%183,0000.1%Medical
Fulcrum Therapeutics, Inc. stock logo
FULC
Fulcrum Therapeutics
$5,355,000$5,355,000 New Holding1,500,0000.1%Medical
HELIX ACQUISITION CORP II
$5,224,9500.0%500,0000.1%CL A ORD SHS
Biodesix, Inc. stock logo
BDSX
Biodesix
$3,869,5060.0%2,173,8800.1%Medical
PRECISION BIOSCIENCES INC
$3,819,5850.0%426,2930.1%COM NEW
Mereo BioPharma Group plc stock logo
MREO
Mereo BioPharma Group
$3,352,617$1,798,240 -34.9%815,7220.1%Medical
Lyra Therapeutics, Inc. stock logo
LYRA
Lyra Therapeutics
$3,278,6930.0%12,757,5620.1%Medical
Nanobiotix S.A. stock logo
NBTX
Nanobiotix
$3,191,6300.0%555,0660.1%Medical
Absci Co. stock logo
ABSI
Absci
$2,674,0000.0%700,0000.1%Medical
Athira Pharma, Inc. stock logo
ATHA
Athira Pharma
$2,409,7220.0%5,402,9640.1%Medical
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
$2,372,9720.0%3,545,4540.1%Medical
enVVeno Medical Corporation stock logo
NVNO
enVVeno Medical
$2,332,898$238,560 11.4%694,3150.0%Medical
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
$2,187,261$2,187,261 New Holding46,2130.0%Medical
TRINITY BIOTECH PLC
$1,980,0000.0%1,800,0000.0%SPONS ADR NEW
Pyxis Oncology, Inc. stock logo
PYXS
Pyxis Oncology
$1,866,056$1,866,056 New Holding508,4620.0%Medical
iRhythm Technologies, Inc. stock logo
IRTC
iRhythm Technologies
$1,677,156$936,463 -35.8%22,5910.0%Medical
Structure Therapeutics Inc. stock logo
GPCR
Structure Therapeutics
$1,529,6540.0%34,8520.0%Medical
LEXEO THERAPEUTICS INC
$1,264,108$1,264,108 New Holding139,8350.0%COM
Novavax, Inc. stock logo
NVAX
Novavax
$1,263,0000.0%100,0000.0%Medical
Fate Therapeutics, Inc. stock logo
FATE
Fate Therapeutics
$1,209,5130.0%345,5750.0%Medical
SINGULAR GENOMICS SYSTEMS IN
$797,540$313,400 -28.2%50,8960.0%COM NEW
KYVERNA THERAPEUTICS INC
$733,5000.0%150,0000.0%COM

Showing largest 100 holdings. View all holdings.
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