Perceptive Advisors LLC Top Holdings and 13F Report (2024) → Dems have chosen Biden replacement? (From Paradigm Press) (Ad) About Perceptive Advisors LLCInvestment ActivityPerceptive Advisors LLC has $5.76 billion in total holdings as of March 31, 2024.Perceptive Advisors LLC owns shares of 108 different stocks, but just 39 companies or ETFs make up 80% of its holdings.Approximately 26.48% of the portfolio was purchased this quarter.About 14.10% of the portfolio was sold this quarter.This quarter, Perceptive Advisors LLC has purchased 99 new stocks and bought additional shares in 39 stocks.Perceptive Advisors LLC sold shares of 18 stocks and completely divested from 17 stocks this quarter.Largest Holdings Cerevel Therapeutics $456,299,409Amicus Therapeutics $330,516,832Iovance Biotherapeutics $285,625,572Arcellx $273,578,820Nuvalent $209,009,561 Largest New Holdings this Quarter Viking Therapeutics $81,516,036 HoldingCG ONCOLOGY INC $57,250,210 HoldingPRAXIS PRECISION MEDICINES I $50,133,361 HoldingCentessa Pharmaceuticals $34,841,369 HoldingOcular Therapeutix $30,252,659 Holding Largest Purchases this Quarter Iovance Biotherapeutics 7,293,576 shares (about $108.09M)Fusion Pharmaceuticals 4,074,000 shares (about $86.86M)Viking Therapeutics 994,098 shares (about $81.52M)Madrigal Pharmaceuticals 278,802 shares (about $74.45M)Neurocrine Biosciences 533,615 shares (about $73.60M) Largest Sales this Quarter SPDR S&P Biotech ETF 1,850,000 shares (about $175.55M)Arcellx 611,253 shares (about $42.51M)AbbVie 131,500 shares (about $23.95M)EyePoint Pharmaceuticals 750,000 shares (about $15.50M)BridgeBio Pharma 336,900 shares (about $10.42M) Sector Allocation Over TimeMap of 500 Largest Holdings ofPerceptive Advisors LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorCERECerevel Therapeutics$456,299,409$7,199,300 ▼-1.6%10,794,8767.9%MedicalFOLDAmicus Therapeutics$330,516,8320.0%28,057,4565.7%MedicalIOVAIovance Biotherapeutics$285,625,572$108,090,738 ▲60.9%19,272,9915.0%MedicalACLXArcellx$273,578,820$42,512,646 ▼-13.4%3,933,5564.8%MedicalNUVLNuvalent$209,009,561$10,102,383 ▼-4.6%2,783,4543.6%MedicalAPOGEE THERAPEUTICS INC$179,371,475$57,907,454 ▲47.7%2,699,3453.1%COMINBXInhibrx$148,793,3960.0%4,256,1042.6%MedicalFUSNFusion Pharmaceuticals$145,517,421$86,857,680 ▲148.1%6,825,3952.5%MedicalRYTMRhythm Pharmaceuticals$141,627,528$48,289,942 ▲51.7%3,268,5792.5%MedicalPCVXVaxcyte$132,026,767$57,672,289 ▲77.6%1,932,7592.3%MedicalSLNOSoleno Therapeutics$131,590,3980.0%3,074,5422.3%MedicalMDTMedtronic$124,586,415$39,471,194 ▲46.4%1,429,5632.2%MedicalMDGLMadrigal Pharmaceuticals$114,814,649$74,451,286 ▲184.5%429,9532.0%MedicalSWTXSpringWorks Therapeutics$111,358,380$15,022,732 ▲15.6%2,262,4621.9%MedicalNBIXNeurocrine Biosciences$110,944,089$73,596,181 ▲197.1%804,4091.9%MedicalIMVTImmunovant$98,972,380$23,752,050 ▲31.6%3,063,2121.7%MedicalSPYRE THERAPEUTICS INC$96,974,834$1,896,500 ▼-1.9%2,556,6791.7%COM NEWBHVNBiohaven$94,342,8200.0%1,725,0471.6%MedicalSLDBSolid Biosciences$91,996,524$45,430,697 ▲97.6%6,906,6461.6%MedicalATXSAstria Therapeutics$91,249,859$34,912,594 ▲62.0%6,485,4201.6%MedicalAXSMAxsome Therapeutics$88,206,212$5,372,296 ▲6.5%1,105,3411.5%MedicalVKTXViking Therapeutics$81,516,036$81,516,036 ▲New Holding994,0981.4%MedicalEOLSEvolus$80,553,172$25,065,236 ▲45.2%5,753,7981.4%MedicalLYRALyra Therapeutics$79,352,0350.0%12,757,5621.4%MedicalIRONDisc Medicine$77,194,057$13,499,275 ▲21.2%1,239,8661.3%MedicalCARGO THERAPEUTICS INC$76,959,449$254,537 ▲0.3%3,448,0041.3%COMITCIIntra-Cellular Therapies$73,030,566$65,556,966 ▲877.2%1,055,3551.3%MedicalNTRANatera$69,255,799$8,505,780 ▼-10.9%757,2251.2%MedicalCRNXCrinetics Pharmaceuticals$69,101,062$10,330,546 ▲17.6%1,476,2031.2%MedicalMGTXMeiraGTx$68,723,7110.0%11,331,1031.2%MedicalSRPTSarepta Therapeutics$68,054,921$9,555,443 ▲16.3%525,6831.2%MedicalVRDNViridian Therapeutics$64,035,803$33,739,791 ▲111.4%3,657,0991.1%MedicalVRNAVerona Pharma$60,523,758$1,683,625 ▼-2.7%3,761,5761.1%MedicalAPLTApplied Therapeutics$57,834,000$26,688,307 ▲85.7%8,505,0001.0%MedicalCG ONCOLOGY INC$57,250,210$57,250,210 ▲New Holding1,304,1051.0%COMAORTArtivion$56,475,574$36,768,166 ▲186.6%2,668,9781.0%MedicalARVNArvinas$51,046,972$36,430,467 ▲249.2%1,236,6030.9%MedicalCELCCelcuity$51,025,226$19,029,146 ▲59.5%2,362,2790.9%MedicalPRAXIS PRECISION MEDICINES I$50,133,361$50,133,361 ▲New Holding821,5890.9%COM NEWRCKTRocket Pharmaceuticals$48,520,772$2,523,470 ▲5.5%1,801,0680.8%MedicalIMTXImmatics$48,161,118$11,465,453 ▲31.2%4,582,4090.8%MedicalTARSTarsus Pharmaceuticals$47,124,7220.0%1,296,4160.8%MedicalBBIOBridgeBio Pharma$43,660,060$10,416,948 ▼-19.3%1,412,0330.8%MedicalADMAADMA Biologics$42,460,2350.0%6,433,3690.7%MedicalEWTXEdgewise Therapeutics$42,310,343$32,177,020 ▲317.5%2,319,6460.7%MedicalVRCAVerrica Pharmaceuticals$42,027,1570.0%7,099,1820.7%MedicalISRGIntuitive Surgical$40,627,362$18,677,412 ▲85.1%101,8000.7%MedicalXENEXenon Pharmaceuticals$38,409,554$8,977,647 ▼-18.9%892,2080.7%MedicalNAUTNautilus Biotechnology$37,026,9800.0%12,594,2110.6%MedicalAKROAkero Therapeutics$35,047,517$10,601,521 ▲43.4%1,387,4710.6%MedicalCNTACentessa Pharmaceuticals$34,841,369$34,841,369 ▲New Holding3,083,3070.6%MedicalLABPLandos Biopharma$31,940,5660.0%1,486,9910.6%MedicalOCULOcular Therapeutix$30,252,659$30,252,659 ▲New Holding3,324,4680.5%MedicalTMCITreace Medical Concepts$30,079,650$13,761,865 ▲84.3%2,304,9540.5%MedicalCABACabaletta Bio$29,286,220$4,885,950 ▼-14.3%1,716,6600.5%MedicalPTGXProtagonist Therapeutics$28,765,764$17,678,052 ▲159.4%994,3230.5%MedicalIRTCiRhythm Technologies$28,443,780$28,443,780 ▲New Holding245,2050.5%MedicalALDXAldeyra Therapeutics$28,101,0260.0%8,593,5860.5%MedicalAUTLAutolus Therapeutics$27,630,153$15,947,308 ▲136.5%4,330,7450.5%MedicalACRVAcrivon Therapeutics$21,506,1850.0%3,007,8580.4%MedicalPEPGPepGen$20,733,439$20,733,439 ▲New Holding1,410,4380.4%MedicalRVMDRevolution Medicines$19,946,664$6,445,903 ▼-24.4%618,8850.3%MedicalABBVAbbVie$19,393,650$23,946,150 ▼-55.3%106,5000.3%MedicalMLTXMoonLake Immunotherapeutics$17,028,573$12,889,721 ▲311.4%339,0120.3%MedicalENGENE HOLDINGS INC$16,931,152$16,931,152 ▲New Holding998,8880.3%COMLIVNLivaNova$16,726,060$16,726,060 ▲New Holding299,0000.3%MedicalATHAAthira Pharma$14,804,1210.0%5,402,9640.3%MedicalTCMDTactile Systems Technology$14,675,131$3,183,797 ▲27.7%903,0850.3%MedicalOBIOOrchestra BioMed$13,416,793$599,684 ▲4.7%2,545,8810.2%MedicalAXGNAxoGen$12,540,207$6,016,580 ▲92.2%1,553,9290.2%MedicalEYPTEyePoint Pharmaceuticals$12,187,983$15,502,500 ▼-56.0%589,6460.2%MedicalZYMEZymeworks$11,306,9700.0%1,074,8070.2%MedicalRAPTRAPT Therapeutics$10,986,779$8,229,973 ▼-42.8%1,223,4720.2%MedicalTYRATyra Biosciences$10,974,208$5,070,208 ▲85.9%669,1590.2%MedicalPRCTPROCEPT BioRobotics$10,410,768$10,410,768 ▲New Holding210,6590.2%MedicalMORFMorphic$10,145,379$8,139,683 ▲405.8%288,2210.2%MedicalSPRYARS Pharmaceuticals$8,864,000$8,864,000 ▲New Holding867,3190.2%MedicalARQTArcutis Biotherapeutics$7,432,500$7,432,500 ▲New Holding750,0000.1%MedicalARRIVENT BIOPHARMA INC$7,411,900$7,411,900 ▲New Holding415,0000.1%COMPRECISION BIOSCIENCES INC$6,515,349$6,515,349 ▲New Holding480,4830.1%COM NEWCOGTCogent Biosciences$5,935,998$1,610,280 ▼-21.3%883,3330.1%MedicalKALVKalVista Pharmaceuticals$5,930,000$5,930,000 ▲New Holding500,0000.1%MedicalIBRXImmunityBio$5,654,003$5,654,003 ▲New Holding1,052,8870.1%MedicalAMLXAmylyx Pharmaceuticals$5,620,715$312,400 ▲5.9%1,979,1250.1%MedicalMGNXMacroGenics$5,568,973$3,438,665 ▼-38.2%378,3270.1%MedicalHELIX ACQUISITION CORP II$5,200,000$5,200,000 ▲New Holding500,0000.1%CL A ORD SHSXFORX4 Pharmaceuticals$4,928,1810.0%3,545,4540.1%MedicalXBISPDR S&P Biotech ETF$4,744,500$175,546,500 ▼-97.4%50,0000.1%ETFESTAEstablishment Labs$4,189,0190.0%82,2990.1%MedicalNAMSNewAmsterdam Pharma$4,138,750$4,138,750 ▲New Holding175,0000.1%MedicalABSIAbsci$3,976,000$3,976,000 ▲New Holding700,0000.1%MedicalVERUVeru$3,909,8480.0%5,584,6990.1%MedicalKYVERNA THERAPEUTICS INC$3,726,000$3,726,000 ▲New Holding150,0000.1%COMTRINITY BIOTECH PLC$3,672,000$3,672,000 ▲New Holding1,800,0000.1%SPONS ADR NEWNBTXNanobiotix$3,607,8730.0%555,0660.1%MedicalNVNOenVVeno Medical$3,390,8340.0%623,3150.1%MedicalNVAXNovavax$3,346,000$3,346,000 ▼-50.0%700,0000.1%MedicalRVNCRevance Therapeutics$2,952,000$2,952,000 ▲New Holding600,0000.1%MedicalAGIOAgios Pharmaceuticals$2,924,000$2,924,000 ▲New Holding100,0000.1%MedicalFBRXForte Biosciences$2,273,3430.0%3,265,3590.0%MedicalShowing largest 100 holdings. 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