Ra Capital Management, L.P. Top Holdings and 13F Report (2024) About Ra Capital Management, L.P.Investment ActivityRa Capital Management, L.P. has $8.67 billion in total holdings as of September 30, 2024.Ra Capital Management, L.P. owns shares of 81 different stocks, but just 25 companies or ETFs make up 80% of its holdings.Approximately 7.79% of the portfolio was purchased this quarter.About 5.33% of the portfolio was sold this quarter.This quarter, Ra Capital Management, L.P. has purchased 78 new stocks and bought additional shares in 9 stocks.Ra Capital Management, L.P. sold shares of 14 stocks and completely divested from 6 stocks this quarter.Largest Holdings Ascendis Pharma A/S $1,449,864,005Vaxcyte $992,913,741Janux Therapeutics $416,395,570Legend Biotech $365,812,894Rhythm Pharmaceuticals $318,762,345 Largest New Holdings this Quarter BICARA THERAPEUTICS INC $177,169,142 HoldingARTIVA BIOTHERAPEUTICS INC $152,233,516 HoldingBIOAGE LABS INC $45,980,251 HoldingIDEAYA Biosciences $42,680,943 HoldingMBX BIOSCIENCES INC $39,264,457 Holding Largest Purchases this Quarter BICARA THERAPEUTICS INC 6,955,993 shares (about $177.17M)ARTIVA BIOTHERAPEUTICS INC 9,853,302 shares (about $152.23M)Vaxcyte 485,436 shares (about $55.47M)BIOAGE LABS INC 2,210,589 shares (about $45.98M)IDEAYA Biosciences 1,347,252 shares (about $42.68M) Largest Sales this Quarter Verona Pharma 2,622,993 shares (about $75.46M)Geron 13,916,670 shares (about $63.18M)Ascendis Pharma A/S 397,972 shares (about $59.42M)PRAXIS PRECISION MEDICINES I 473,644 shares (about $27.25M)Enliven Therapeutics 1,061,232 shares (about $27.10M) Sector Allocation Over TimeMap of 500 Largest Holdings ofRa Capital Management, L.P. Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorASNDAscendis Pharma A/S$1,449,864,005$59,421,199 ▼-3.9%9,710,42816.7%MedicalPCVXVaxcyte$992,913,741$55,470,772 ▲5.9%8,689,19011.4%MedicalJANXJanux Therapeutics$416,395,5700.0%9,165,6524.8%MedicalLEGNLegend Biotech$365,812,8940.0%7,506,9344.2%MedicalRYTMRhythm Pharmaceuticals$318,762,3450.0%6,084,4123.7%MedicalRNAAvidity Biosciences$289,377,739$41,337,000 ▲16.7%6,300,4083.3%MedicalTYRATyra Biosciences$244,894,4780.0%10,416,6092.8%MedicalEVHEvolent Health$240,800,2970.0%8,514,8622.8%Computer and TechnologyEWTXEdgewise Therapeutics$237,783,6390.0%8,909,0912.7%MedicalBIIBBiogen$229,594,951$39,217,127 ▲20.6%1,184,4562.6%MedicalDYNE THERAPEUTICS INC$229,210,692$11,923,285 ▲5.5%6,381,1442.6%SHRXSTRxSight$193,608,660$10,973,460 ▲6.0%3,916,8252.2%MedicalBICARA THERAPEUTICS INC$177,169,142$177,169,142 ▲New Holding6,955,9932.0%SHELYMEliem Therapeutics$159,924,0690.0%31,419,2671.8%MedicalSPRYARS Pharmaceuticals$157,484,1670.0%10,860,9771.8%MedicalACLXArcellx$154,617,011$20,665,802 ▲15.4%1,851,4791.8%MedicalARTIVA BIOTHERAPEUTICS INC$152,233,516$152,233,516 ▲New Holding9,853,3021.8%SHWVEWave Life Sciences$149,256,4740.0%18,202,0091.7%MedicalGERNGeron$146,577,328$63,181,682 ▼-30.1%32,285,7551.7%MedicalVRNAVerona Pharma$144,127,717$75,463,509 ▼-34.4%5,009,6531.7%MedicalNAMSNewAmsterdam Pharma$133,862,4000.0%8,064,0001.5%MedicalAPOGEE THERAPEUTICS INC$115,239,8330.0%1,961,8631.3%SHDAWNDay One Biopharmaceuticals$109,653,0740.0%7,871,7211.3%MedicalETNB89bio$104,897,9450.0%14,175,3981.2%MedicalRXRXRecursion Pharmaceuticals$101,384,6130.0%15,384,6151.2%MedicalLENZ THERAPEUTICS INC$99,205,2580.0%4,178,8231.1%SHPEPGPepGen$91,395,6100.0%10,689,5451.1%MedicalAXSMAxsome Therapeutics$89,870,0000.0%1,000,0001.0%MedicalGPCRStructure Therapeutics$83,249,3230.0%1,896,7721.0%MedicalTOURMALINE BIO INC$65,275,7620.0%2,538,9250.8%SHDIANTHUS THERAPEUTICS INC$63,877,5400.0%2,333,0000.7%SHMLYSMineralys Therapeutics$58,745,4160.0%4,850,9840.7%MedicalACRVAcrivon Therapeutics$58,383,5560.0%8,340,5080.7%MedicalATXSAstria Therapeutics$56,208,395$676,642 ▲1.2%5,105,2130.6%MedicalFDMT4D Molecular Therapeutics$55,111,6610.0%5,098,2110.6%MedicalCG ONCOLOGY INC$52,725,1470.0%1,397,4330.6%SHBCYCBicycle Therapeutics$50,985,3900.0%2,253,0000.6%MedicalNKTXNkarta$48,839,1830.0%10,805,1290.6%MedicalBIOAGE LABS INC$45,980,251$45,980,251 ▲New Holding2,210,5890.5%SHGHRSGH Research$44,733,949$568,650 ▲1.3%6,686,6890.5%MedicalPRAXIS PRECISION MEDICINES I$43,842,891$27,253,476 ▼-38.3%761,9550.5%SHIDYAIDEAYA Biosciences$42,680,943$42,680,943 ▲New Holding1,347,2520.5%MedicalLRMRLarimar Therapeutics$39,597,0490.0%6,045,3510.5%MedicalMBX BIOSCIENCES INC$39,264,457$39,264,457 ▲New Holding1,511,3340.5%SHABOSAcumen Pharmaceuticals$37,031,5160.0%14,932,0630.4%MedicalFULCFulcrum Therapeutics$36,517,883$4,928,760 ▼-11.9%10,229,0990.4%MedicalITOSiTeos Therapeutics$32,515,899$3,395,315 ▼-9.5%3,184,7110.4%MedicalSLDBSolid Biosciences$30,183,2090.0%4,330,4460.3%MedicalCCCCC4 Therapeutics$27,804,6000.0%4,878,0000.3%MedicalELVNEnliven Therapeutics$27,103,891$27,103,865 ▼-50.0%1,061,2330.3%MedicalALTO NEUROSCIENCE INC$23,739,762$118,976 ▼-0.5%2,075,1540.3%SHSERASera Prognostics$23,655,9020.0%3,032,8080.3%MedicalTSHATaysha Gene Therapies$21,853,7310.0%10,872,5030.3%MedicalIMTXImmatics$19,967,5000.0%1,750,0000.2%MedicalAVTEAerovate Therapeutics$19,211,4720.0%9,192,0920.2%MedicalNUVLNuvalent$18,033,546$5,779,132 ▲47.2%176,2810.2%MedicalTHRDTF Financial$17,355,192$10,192,716 ▼-37.0%1,280,8260.2%MedicalVORVor Biopharma$15,924,2160.0%22,748,8800.2%MedicalINSMInsmed$14,600,0000.0%200,0000.2%MedicalPLRXPliant Therapeutics$14,360,0100.0%1,281,0000.2%MedicalTNYATenaya Therapeutics$13,476,393$1,234,737 ▼-8.4%6,982,5870.2%MedicalZURAZura Bio$13,063,0620.0%3,217,5030.2%MedicalHOWLWerewolf Therapeutics$13,027,1480.0%6,144,8810.2%MedicalCERVOMED INC$11,929,9520.0%817,1200.1%SHXNCRXencor$11,563,250$11,563,250 ▲New Holding575,0000.1%MedicalACETAdicet Bio$10,859,0400.0%7,541,0000.1%MedicalARVNArvinas$10,377,8010.0%421,3480.1%MedicalAVALO THERAPEUTICS INC$9,186,500$9,186,500 ▲New Holding967,0000.1%SHCMRXChimerix$8,184,0000.0%8,800,0000.1%MedicalBOUNDLESS BIO INC$7,566,7900.0%2,180,6310.1%SHCIDARA THEREAPEUTICS INC$7,558,110$7,558,110 ▲New Holding703,0800.1%SHPERCEPTIVE CAPITAL SOLUTIONS$7,515,0000.0%750,0000.1%SHLEXEO THERAPEUTICS INC$4,940,848$1,140,468 ▼-18.8%546,5540.1%SHTARAProtara Therapeutics$3,477,0000.0%1,900,0000.0%MedicalADAGIO MEDICAL HOLDINGS INC$3,441,529$3,441,529 ▲New Holding1,333,9260.0%SHSURROZEN INC$3,385,3080.0%282,5800.0%SHMETAGENOMI INC$2,832,369$374,347 ▼-11.7%1,305,2390.0%SHNAMSWNewAmsterdam Pharma$2,333,3310.0%333,3330.0%MedicalANTX(ANTX)$2,139,997$3,799,889 ▼-64.0%1,999,9970.0%MedicalRGLSRegulus Therapeutics$1,203,929$8,608,568 ▼-87.7%766,8340.0%MedicalSCLXScilex$241,4860.0%261,1790.0%MedicalLBPHLongboard Pharmaceuticals$0$88,904,887 ▼-100.0%00.0%MedicalURGNUroGen Pharma$0$51,739,955 ▼-100.0%00.0%MedicalNRIXNurix Therapeutics$0$13,565,500 ▼-100.0%00.0%MedicalCYBIN INC$0$11,925,210 ▼-100.0%00.0%SHMGNXMacroGenics$0$8,848,589 ▼-100.0%00.0%MedicalUNCYUnicycive Therapeutics$0$1,318,995 ▼-100.0%00.0%MedicalShowing largest 100 holdings. 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