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Redmile Group, LLC Top Holdings and 13F Report (2025)

About Redmile Group, LLC

Investment Activity

  • Redmile Group, LLC has $1.43 billion in total holdings as of December 31, 2024.
  • Redmile Group, LLC owns shares of 62 different stocks, but just 22 companies or ETFs make up 80% of its holdings.
  • Approximately 3.97% of the portfolio was purchased this quarter.
  • About 14.31% of the portfolio was sold this quarter.
  • This quarter, Redmile Group, LLC has purchased 63 new stocks and bought additional shares in 9 stocks.
  • Redmile Group, LLC sold shares of 40 stocks and completely divested from 4 stocks this quarter.

Largest Holdings

Scholar Rock
$196,645,857
Krystal Biotech
$117,992,396
Nurix Therapeutics
$78,989,093
Zymeworks
$70,864,378

Largest New Holdings this Quarter

CERIBELL INC
$11,263,985 Holding
Insulet
$2,495,568 Holding
Solid Biosciences
$2,460,984 Holding

Largest Purchases this Quarter

CERIBELL INC
435,239 shares (about $11.26M)
RAPT Therapeutics
5,970,785 shares (about $9.43M)
NEUROGENE INC
355,416 shares (about $8.12M)
LivaNova
168,500 shares (about $7.80M)
89bio
597,326 shares (about $4.67M)

Largest Sales this Quarter

Scholar Rock
688,956 shares (about $29.78M)
Kymera Therapeutics
292,824 shares (about $11.78M)
Amicus Therapeutics
1,191,702 shares (about $11.23M)
Krystal Biotech
57,070 shares (about $8.94M)
BioNTech
70,985 shares (about $8.09M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofRedmile Group, LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
Scholar Rock Holding Co. stock logo
SRRK
Scholar Rock
$196,645,857$29,776,678 -13.2%4,549,88113.7%Medical
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
$117,992,396$8,940,586 -7.0%753,1758.2%Medical
Nurix Therapeutics, Inc. stock logo
NRIX
Nurix Therapeutics
$78,989,093$1,664,589 -2.1%4,192,6275.5%Medical
Zymeworks Inc. stock logo
ZYME
Zymeworks
$70,864,378$3,827,599 -5.1%4,840,4634.9%Medical
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
$66,457,064$11,225,833 -14.5%7,054,8904.6%Medical
Replimune Group, Inc. stock logo
REPL
Replimune Group
$59,405,932$1,505,806 2.6%4,905,5274.1%Medical
Immunome, Inc. stock logo
IMNM
Immunome
$51,273,636$653,427 -1.3%4,828,0263.6%Medical
Stoke Therapeutics, Inc. stock logo
STOK
Stoke Therapeutics
$50,667,728$1,322,276 -2.5%4,593,6293.5%Medical
LivaNova PLC stock logo
LIVN
LivaNova
$48,326,291$7,803,235 19.3%1,043,5393.4%Medical
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
$44,270,379$11,780,309 -21.0%1,100,4323.1%Medical
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
$38,133,445$3,977,511 -9.4%2,895,4782.7%Medical
Beam Therapeutics Inc. stock logo
BEAM
Beam Therapeutics
$37,908,462$2,044,661 -5.1%1,528,5672.6%Medical
REGENXBIO Inc. stock logo
RGNX
REGENXBIO
$37,063,649$758,483 -2.0%4,794,7802.6%Medical
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
$34,363,514$4,236,151 -11.0%1,235,2092.4%Medical
Biohaven Ltd. stock logo
BHVN
Biohaven
$33,782,926$4,845,154 -12.5%904,4962.4%Medical
Annexon, Inc. stock logo
ANNX
Annexon
$32,322,304$650,576 -2.0%6,300,6442.3%Medical
ADC Therapeutics SA stock logo
ADCT
ADC Therapeutics
$31,176,795$4,947 0.0%15,666,7312.2%Medical
NEUROGENE INC
$30,169,782$8,124,810 36.9%1,319,7632.1%COM
Boston Scientific Co. stock logo
BSX
Boston Scientific
$27,928,846$1,624,731 -5.5%312,6831.9%Medical
Cogent Biosciences, Inc. stock logo
COGT
Cogent Biosciences
$27,727,721$7,250,443 -20.7%3,554,8361.9%Medical
Absci Co. stock logo
ABSI
Absci
$21,623,6880.0%8,253,3161.5%Medical
Fate Therapeutics, Inc. stock logo
FATE
Fate Therapeutics
$21,240,361$488,583 -2.2%12,872,9461.5%Medical
IGM Biosciences, Inc. stock logo
IGMS
IGM Biosciences
$18,037,520$735,320 -3.9%2,952,1311.3%Medical
89bio, Inc. stock logo
ETNB
89bio
$16,947,316$4,671,089 38.0%2,167,1761.2%Medical
Silence Therapeutics plc stock logo
SLN
Silence Therapeutics
$16,507,301$3,440,000 26.3%2,399,3171.2%Medical
IDEAYA Biosciences, Inc. stock logo
IDYA
IDEAYA Biosciences
$15,916,010$1,589,545 -9.1%619,3001.1%Medical
Celldex Therapeutics, Inc. stock logo
CLDX
Celldex Therapeutics
$15,560,634$1,046,178 -6.3%615,7751.1%Medical
Establishment Labs Holdings Inc. stock logo
ESTA
Establishment Labs
$14,749,264$2,688,000 22.3%320,1491.0%Medical
Immunovant, Inc. stock logo
IMVT
Immunovant
$14,164,080$1,743,932 -11.0%571,8241.0%Medical
CERIBELL INC
$11,263,985$11,263,985 New Holding435,2390.8%COM
Stryker Co. stock logo
SYK
Stryker
$11,044,894$743,503 -6.3%30,6760.8%Medical
RAPT Therapeutics, Inc. stock logo
RAPT
RAPT Therapeutics
$10,231,001$9,433,840 1,183.4%6,475,3170.7%Medical
BioNTech SE stock logo
BNTX
BioNTech
$9,511,520$8,088,740 -46.0%83,4710.7%Medical
Intuitive Surgical, Inc. stock logo
ISRG
Intuitive Surgical
$8,843,568$5,091,720 -36.5%16,9430.6%Medical
Keros Therapeutics, Inc. stock logo
KROS
Keros Therapeutics
$8,746,1700.0%552,5060.6%Medical
Nuvation Bio Inc. stock logo
NUVB
Nuvation Bio
$8,062,4840.0%3,031,0090.6%Medical
Ardelyx, Inc. stock logo
ARDX
Ardelyx
$7,991,633$428,435 -5.1%1,576,2590.6%Medical
ORUKA THERAPEUTICS INC
$7,983,4060.0%411,7280.6%COM
Verve Therapeutics, Inc. stock logo
VERV
Verve Therapeutics
$7,434,445$367,739 -4.7%1,318,1640.5%Medical
Shattuck Labs, Inc. stock logo
STTK
Shattuck Labs
$6,703,066$91,676 -1.3%5,539,7240.5%Medical
4D Molecular Therapeutics, Inc. stock logo
FDMT
4D Molecular Therapeutics
$6,666,789$363,053 -5.2%1,196,9100.5%Medical
ALX Oncology Holdings Inc. stock logo
ALXO
ALX Oncology
$6,161,650$245,432 -3.8%3,689,6110.4%Medical
Penumbra, Inc. stock logo
PEN
Penumbra
$6,113,448$2,825,062 85.9%25,7430.4%Medical
Prime Medicine, Inc. stock logo
PRME
Prime Medicine
$6,057,1020.0%2,074,3500.4%Medical
ATARA BIOTHERAPEUTICS INC
$5,879,040$140,673 -2.3%441,7010.4%COM NEW
Cytokinetics, Incorporated stock logo
CYTK
Cytokinetics
$4,355,810$212,527 -4.7%92,5980.3%Medical
Stereotaxis, Inc. stock logo
STXS
Stereotaxis
$4,102,780$703,959 -14.6%1,799,4650.3%Medical
Allakos Inc. stock logo
ALLK
Allakos
$3,648,267$75,905 -2.0%3,015,0970.3%Medical
Astria Therapeutics, Inc. stock logo
ATXS
Astria Therapeutics
$3,095,725$316,422 11.4%346,2780.2%Medical
AC Immune SA stock logo
ACIU
AC Immune
$2,792,607$1,781,643 -38.9%1,034,2990.2%Medical
Repare Therapeutics Inc. stock logo
RPTX
Repare Therapeutics
$2,510,077$34,670 -1.4%1,916,0890.2%Medical
Insulet Co. stock logo
PODD
Insulet
$2,495,568$2,495,568 New Holding9,5590.2%Medical
Solid Biosciences Inc. stock logo
SLDB
Solid Biosciences
$2,460,984$2,460,984 New Holding615,2460.2%Medical
BOUNDLESS BIO INC
$2,146,592$821,698 -27.7%740,2040.1%COM
LAVA Therapeutics stock logo
LVTX
LAVA Therapeutics
$1,972,7280.0%2,074,3720.1%Medical
Achilles Therapeutics plc stock logo
ACHL
Achilles Therapeutics
$1,833,2210.0%1,608,0890.1%Medical
Xeris Biopharma Holdings, Inc. stock logo
XERS
Xeris Biopharma
$1,529,226$2,018,705 -56.9%451,0990.1%Medical
Invivyd, Inc. stock logo
IVVD
Invivyd
$1,334,730$23,688 -1.7%3,012,2540.1%Medical
AlloVir, Inc. stock logo
ALVR
AlloVir
$801,3470.0%1,907,9690.1%Medical
Adaptimmune Therapeutics plc stock logo
ADAP
Adaptimmune Therapeutics
$385,4970.0%715,6070.0%Medical
Ventyx Biosciences, Inc. stock logo
VTYX
Ventyx Biosciences
$271,950$4,342,854 -94.1%124,1780.0%Medical
HOOKIPA PHARMA INC
$213,8160.0%106,3760.0%COM NEW
Augmedix, Inc. stock logo
AUGX
Augmedix
$0$38,493,768 -100.0%00.0%Medical
Catalent, Inc. stock logo
CTLT
Catalent
$0$36,073,675 -100.0%00.0%Medical
Gritstone bio, Inc. stock logo
GRTS
Gritstone bio
$0$2,853,211 -100.0%00.0%Medical
Cabaletta Bio, Inc. stock logo
CABA
Cabaletta Bio
$0$2,090,139 -100.0%00.0%Medical

Showing largest 100 holdings. View all holdings.
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