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Rock Springs Capital Management Lp Top Holdings and 13F Report (2024)

About Rock Springs Capital Management Lp

Investment Activity

  • Rock Springs Capital Management Lp has $3.07 billion in total holdings as of September 30, 2024.
  • Rock Springs Capital Management Lp owns shares of 109 different stocks, but just 42 companies or ETFs make up 80% of its holdings.
  • Approximately 5.56% of the portfolio was purchased this quarter.
  • About 18.37% of the portfolio was sold this quarter.
  • This quarter, Rock Springs Capital Management Lp has purchased 110 new stocks and bought additional shares in 33 stocks.
  • Rock Springs Capital Management Lp sold shares of 31 stocks and completely divested from 7 stocks this quarter.

Largest Holdings

UnitedHealth Group
$172,042,090
Intuitive Surgical
$132,642,900
argenx
$126,575,680

Largest New Holdings this Quarter

Summit Therapeutics
$22,776,000 Holding
ZENAS BIOPHARMA INC
$14,867,046 Holding
BICARA THERAPEUTICS INC
$11,358,983 Holding
Cytokinetics
$10,882,502 Holding
Xencor
$8,064,371 Holding

Largest Purchases this Quarter

Summit Therapeutics
1,040,000 shares (about $22.78M)
Eli Lilly and Company
20,500 shares (about $18.16M)
Nuvalent
174,005 shares (about $17.80M)
ZENAS BIOPHARMA INC
878,667 shares (about $14.87M)
BICARA THERAPEUTICS INC
445,975 shares (about $11.36M)

Largest Sales this Quarter

Blueprint Medicines
1,748,641 shares (about $161.75M)
Evolent Health
2,007,500 shares (about $56.77M)
Boston Scientific
357,500 shares (about $29.96M)
Acadia Healthcare
362,500 shares (about $22.99M)
Agios Pharmaceuticals
344,872 shares (about $15.32M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofRock Springs Capital Management Lp

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
UnitedHealth Group Incorporated stock logo
UNH
UnitedHealth Group
$172,042,090$11,255,090 7.0%294,2505.6%Medical
Intuitive Surgical, Inc. stock logo
ISRG
Intuitive Surgical
$132,642,900$14,001,195 -9.5%270,0004.3%Medical
argenx SE stock logo
ARGX
argenx
$126,575,680$2,303,840 1.9%233,5004.1%Medical
Eli Lilly and Company stock logo
LLY
Eli Lilly and Company
$125,803,480$18,161,770 16.9%142,0004.1%Medical
Ultragenyx Pharmaceutical Inc. stock logo
RARE
Ultragenyx Pharmaceutical
$109,893,010$3,010,810 2.8%1,978,2723.6%Medical
Neurocrine Biosciences, Inc. stock logo
NBIX
Neurocrine Biosciences
$108,191,580$115,220 -0.1%939,0003.5%Medical
Exact Sciences Co. stock logo
EXAS
Exact Sciences
$78,167,700$4,495,920 6.1%1,147,5002.5%Medical
Blueprint Medicines Co. stock logo
BPMC
Blueprint Medicines
$71,111,780$161,749,293 -69.5%768,7762.3%Medical
Alnylam Pharmaceuticals, Inc. stock logo
ALNY
Alnylam Pharmaceuticals
$68,757,5000.0%250,0002.2%Medical
Travere Therapeutics, Inc. stock logo
TVTX
Travere Therapeutics
$65,535,819$2,828,932 4.5%4,684,4762.1%Medical
Rhythm Pharmaceuticals, Inc. stock logo
RYTM
Rhythm Pharmaceuticals
$64,339,792$2,745,236 -4.1%1,228,0932.1%Medical
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
$61,639,032$7,470,450 -10.8%1,580,4882.0%Medical
Freshpet, Inc. stock logo
FRPT
Freshpet
$61,067,805$4,581,795 -7.0%446,5002.0%Consumer Staples
Evolent Health, Inc. stock logo
EVH
Evolent Health
$58,539,600$56,772,100 -49.2%2,070,0001.9%Computer and Technology
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
$55,827,018$3,727,220 7.2%263,0621.8%Medical
Phreesia, Inc. stock logo
PHR
Phreesia
$52,018,175$3,076,650 -5.6%2,282,5001.7%Medical
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
$51,829,699$1,716,532 3.4%1,316,4771.7%Medical
Acadia Healthcare Company, Inc. stock logo
ACHC
Acadia Healthcare
$51,679,150$22,986,125 -30.8%815,0001.7%Medical
Penumbra, Inc. stock logo
PEN
Penumbra
$51,492,1500.0%265,0001.7%Medical
West Pharmaceutical Services, Inc. stock logo
WST
West Pharmaceutical Services
$50,351,840$6,678,560 15.3%167,7501.6%Medical
Insmed Incorporated stock logo
INSM
Insmed
$49,884,112$9,125,876 -15.5%683,3441.6%Medical
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
$49,667,439$5,423,403 -9.8%1,049,3861.6%Medical
Ascendis Pharma A/S stock logo
ASND
Ascendis Pharma A/S
$48,525,750$5,225,850 12.1%325,0001.6%Medical
Humana Inc. stock logo
HUM
Humana
$46,877,520$187,510 0.4%148,0001.5%Medical
Structure Therapeutics Inc. stock logo
GPCR
Structure Therapeutics
$46,695,010$68,117 -0.1%1,063,9101.5%Medical
Revolution Medicines, Inc. stock logo
RVMD
Revolution Medicines
$45,801,006$3,027,113 7.1%1,009,9451.5%Medical
Merus stock logo
MRUS
Merus
$44,591,748$5,421,859 -10.8%892,5491.5%Medical
Nuvalent, Inc. stock logo
NUVL
Nuvalent
$43,988,386$17,800,711 68.0%429,9941.4%Medical
Mereo BioPharma Group plc stock logo
MREO
Mereo BioPharma Group
$39,185,439$1,030,287 2.7%9,534,1701.3%Medical
Boston Scientific Co. stock logo
BSX
Boston Scientific
$38,548,000$29,958,500 -43.7%460,0001.3%Medical
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$38,403,675$2,934,915 8.3%307,5001.2%Medical
Edwards Lifesciences Co. stock logo
EW
Edwards Lifesciences
$38,069,631$1,775,131 4.9%576,9001.2%Medical
Celldex Therapeutics, Inc. stock logo
CLDX
Celldex Therapeutics
$37,517,414$10,034,392 -21.1%1,103,7781.2%Medical
agilon health, inc. stock logo
AGL
agilon health
$35,750,424$773,424 2.2%9,096,8001.2%Medical
DexCom, Inc. stock logo
DXCM
DexCom
$35,128,960$1,608,960 4.8%524,0001.1%Medical
Immunovant, Inc. stock logo
IMVT
Immunovant
$34,819,520$1,016,524 3.0%1,221,3091.1%Medical
Zai Lab Limited stock logo
ZLAB
Zai Lab
$31,760,346$429,692 1.4%1,315,6731.0%Medical
Insulet Co. stock logo
PODD
Insulet
$31,188,500$14,197,750 -31.3%134,0001.0%Medical
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
$31,073,853$15,322,663 -33.0%699,3891.0%Medical
iRhythm Technologies, Inc. stock logo
IRTC
iRhythm Technologies
$29,510,4000.0%397,5001.0%Medical
Align Technology, Inc. stock logo
ALGN
Align Technology
$29,119,640$3,306,160 -10.2%114,5000.9%Medical
BioCryst Pharmaceuticals, Inc. stock logo
BCRX
BioCryst Pharmaceuticals
$27,529,921$23,560 0.1%3,622,3580.9%Medical
Inspire Medical Systems, Inc. stock logo
INSP
Inspire Medical Systems
$27,436,5000.0%130,0000.9%Medical
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
$26,779,217$4,041,331 -13.1%933,3990.9%Medical
Azenta, Inc. stock logo
AZTA
Azenta
$25,794,300$7,919,940 -23.5%532,5000.8%Medical
Legend Biotech Co. stock logo
LEGN
Legend Biotech
$24,800,256$153,305 0.6%508,9320.8%Medical
Warby Parker Inc. stock logo
WRBY
Warby Parker
$23,499,687$10,466,714 -30.8%1,439,0500.8%Consumer Staples
Summit Therapeutics Inc. stock logo
SMMT
Summit Therapeutics
$22,776,000$22,776,000 New Holding1,040,0000.7%Medical
LifeStance Health Group, Inc. stock logo
LFST
LifeStance Health Group
$21,707,000$12,086,900 -35.8%3,101,0000.7%Medical
Oscar Health, Inc. stock logo
OSCR
Oscar Health
$21,451,794$5,092,521 -19.2%1,011,4000.7%Finance
Inozyme Pharma, Inc. stock logo
INZY
Inozyme Pharma
$19,889,078$546,582 2.8%3,802,8830.6%Medical
Vera Therapeutics, Inc. stock logo
VERA
Vera Therapeutics
$16,950,346$101,660 0.6%383,4920.6%Medical
DYNE THERAPEUTICS INC
$16,560,1260.0%461,0280.5%COM
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
$15,717,240$1,845,585 -10.5%132,0000.5%Medical
ZENAS BIOPHARMA INC
$14,867,046$14,867,046 New Holding878,6670.5%COM
Applied Therapeutics, Inc. stock logo
APLT
Applied Therapeutics
$14,844,817$1,627,283 12.3%1,746,4490.5%Medical
Crinetics Pharmaceuticals, Inc. stock logo
CRNX
Crinetics Pharmaceuticals
$14,788,3400.0%289,4000.5%Medical
Pharvaris stock logo
PHVS
Pharvaris
$14,018,3620.0%756,9310.5%Medical
Amicus Therapeutics, Inc. stock logo
FOLD
Amicus Therapeutics
$13,352,990$338,556 2.6%1,250,2800.4%Medical
Johnson & Johnson stock logo
JNJ
Johnson & Johnson
$12,964,800$14,585,400 -52.9%80,0000.4%Medical
Cullinan Therapeutics, Inc. stock logo
CGEM
Cullinan Therapeutics
$12,335,940$1,315,362 11.9%736,9140.4%Medical
BICARA THERAPEUTICS INC
$11,358,983$11,358,983 New Holding445,9750.4%COM
Enliven Therapeutics, Inc. stock logo
ELVN
Enliven Therapeutics
$10,945,7030.0%428,5710.4%Medical
NEUMORA THERAPEUTICS INC.
$10,939,214$899,522 9.0%828,1010.4%COM
Cytokinetics, Incorporated stock logo
CYTK
Cytokinetics
$10,882,502$10,882,502 New Holding206,1080.4%Medical
BioMarin Pharmaceutical Inc. stock logo
BMRN
BioMarin Pharmaceutical
$10,613,7900.0%151,0000.3%Medical
Prothena Co. plc stock logo
PRTA
Prothena
$10,457,0530.0%625,0480.3%Medical
Compass Therapeutics, Inc. stock logo
CMPX
Compass Therapeutics
$10,357,800$212,430 2.1%5,629,2390.3%Medical
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
$10,168,378$9,048,347 -47.1%55,8610.3%Medical
Aurinia Pharmaceuticals Inc. stock logo
AUPH
Aurinia Pharmaceuticals
$8,647,4940.0%1,179,7400.3%Medical
JASPER THERAPEUTICS INC
$8,635,445$1,029,904 13.5%459,0880.3%COM NEW
Novavax, Inc. stock logo
NVAX
Novavax
$8,209,500$315,750 -3.7%650,0000.3%Medical
Xencor, Inc. stock logo
XNCR
Xencor
$8,064,371$8,064,371 New Holding401,0130.3%Medical
Nevro Corp. stock logo
NVRO
Nevro
$7,722,5850.0%1,381,5000.3%Medical
Dynavax Technologies Co. stock logo
DVAX
Dynavax Technologies
$6,739,845$7,660,132 -53.2%605,0130.2%Medical
SpringWorks Therapeutics, Inc. stock logo
SWTX
SpringWorks Therapeutics
$6,403,3540.0%199,8550.2%Medical
Biohaven Ltd. stock logo
BHVN
Biohaven
$6,374,0730.0%127,5580.2%Medical
Beam Therapeutics Inc. stock logo
BEAM
Beam Therapeutics
$6,123,1140.0%249,9230.2%Medical
Pacira BioSciences, Inc. stock logo
PCRX
Pacira BioSciences
$6,020,000$5,794,250 -49.0%400,0000.2%Medical
NewAmsterdam Pharma stock logo
NAMS
NewAmsterdam Pharma
$5,865,095$5,865,095 New Holding353,3190.2%Medical
Mersana Therapeutics, Inc. stock logo
MRSN
Mersana Therapeutics
$5,758,4180.0%3,046,7820.2%Medical
Pulmonx Co. stock logo
LUNG
Pulmonx
$5,730,877$322,481 6.0%691,3000.2%Medical
Acumen Pharmaceuticals, Inc. stock logo
ABOS
Acumen Pharmaceuticals
$5,704,1460.0%2,300,0590.2%Medical
PERSPECTIVE THERAPEUTICS INC
$5,532,187$176,220 3.3%414,3960.2%COM NEW
GOSSAMER BIO INC
$5,012,5760.0%9,573,0000.2%NOTE 5.000% 6/0
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
$4,315,8050.0%384,9960.1%Medical
ESSA Pharma Inc. stock logo
EPIX
ESSA Pharma
$4,102,6500.0%677,0050.1%Medical
Edap Tms S.A. stock logo
EDAP
Edap Tms
$3,998,400$237,150 6.3%1,568,0000.1%Medical
Autolus Therapeutics plc stock logo
AUTL
Autolus Therapeutics
$3,749,7460.0%1,032,9880.1%Medical
MacroGenics, Inc. stock logo
MGNX
MacroGenics
$3,466,4990.0%1,053,6470.1%Medical
Leap Therapeutics, Inc. stock logo
LPTX
Leap Therapeutics
$3,255,0230.0%1,266,5460.1%Medical
Gossamer Bio, Inc. stock logo
GOSS
Gossamer Bio
$3,222,5290.0%3,266,9600.1%Medical
Aclaris Therapeutics, Inc. stock logo
ACRS
Aclaris Therapeutics
$3,166,5190.0%2,753,4950.1%Medical
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
$2,365,6670.0%3,003,2590.1%Medical
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
$2,307,200$1,750,588 -43.1%80,0000.1%Medical
Adaptimmune Therapeutics plc stock logo
ADAP
Adaptimmune Therapeutics
$2,305,1650.0%2,425,4680.1%Medical
SAGIMET BIOSCIENCES INC
$2,182,2280.0%787,8080.1%COM SER A
Biomea Fusion, Inc. stock logo
BMEA
Biomea Fusion
$1,829,5850.0%181,1470.1%Medical
Compugen Ltd. stock logo
CGEN
Compugen
$1,791,8820.0%989,9900.1%Medical
Vigil Neuroscience, Inc. stock logo
VIGL
Vigil Neuroscience
$1,604,6570.0%471,9580.1%Medical

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