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Rtw Investments, Lp Top Holdings and 13F Report (2024)

About Rtw Investments, Lp

Investment Activity

  • Rtw Investments, Lp has $6.77 billion in total holdings as of March 31, 2024.
  • Rtw Investments, Lp owns shares of 69 different stocks, but just 27 companies or ETFs make up 80% of its holdings.
  • Approximately 16.47% of the portfolio was purchased this quarter.
  • About 17.90% of the portfolio was sold this quarter.
  • This quarter, Rtw Investments, Lp has purchased 64 new stocks and bought additional shares in 25 stocks.
  • Rtw Investments, Lp sold shares of 6 stocks and completely divested from 11 stocks this quarter.

Largest Holdings

Immunocore
$391,276,665
Axsome Therapeutics
$358,515,784
Bruker
$314,144,284

Largest New Holdings this Quarter

Stryker
$114,876,270 Holding
DYNE THERAPEUTICS INC
$87,770,155 Holding
KYVERNA THERAPEUTICS INC
$46,021,341 Holding
Intuitive Surgical
$39,509,910 Holding
NEUROGENE INC
$39,148,310 Holding

Largest Purchases this Quarter

Stryker
321,000 shares (about $114.88M)
Immatics
8,515,089 shares (about $89.49M)
DYNE THERAPEUTICS INC
3,091,587 shares (about $87.77M)
Merus
1,735,768 shares (about $78.16M)
Shockwave Medical
223,624 shares (about $72.82M)

Largest Sales this Quarter

Madrigal Pharmaceuticals
418,144 shares (about $111.66M)
Vericel
1,606,397 shares (about $83.56M)
Arvinas
915,586 shares (about $37.80M)
CARGO THERAPEUTICS INC
1,440,213 shares (about $32.15M)
Immunocore
76,746 shares (about $4.99M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofRtw Investments, Lp

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
Rocket Pharmaceuticals, Inc. stock logo
RCKT
Rocket Pharmaceuticals
$476,508,5780.0%17,687,7727.0%Medical
Immunocore Holdings plc stock logo
IMCR
Immunocore
$391,276,665$4,988,490 -1.3%6,019,6415.8%Medical
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
$358,515,784$246,023 0.1%4,492,6795.3%Medical
Ultragenyx Pharmaceutical Inc. stock logo
RARE
Ultragenyx Pharmaceutical
$330,897,399$9,339,354 2.9%7,087,1154.9%Medical
Bruker Co. stock logo
BRKR
Bruker
$314,144,2840.0%3,344,0954.6%Computer and Technology
argenx SE stock logo
ARGX
argenx
$262,688,0150.0%667,1953.9%Medical
ACADIA Pharmaceuticals Inc. stock logo
ACAD
ACADIA Pharmaceuticals
$255,704,034$47,625,876 22.9%13,829,3153.8%Medical
Natera, Inc. stock logo
NTRA
Natera
$237,185,3220.0%2,593,3233.5%Medical
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
$215,963,2870.0%7,423,9703.2%Medical
Masimo Co. stock logo
MASI
Masimo
$214,753,4400.0%1,462,4003.2%Medical
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
$203,401,264$32,677,849 19.1%7,970,2693.0%Medical
Merus stock logo
MRUS
Merus
$185,045,967$78,161,633 73.1%4,109,3932.7%Medical
Cytokinetics, Incorporated stock logo
CYTK
Cytokinetics
$177,033,3590.0%2,525,0802.6%Medical
APOGEE THERAPEUTICS INC
$163,971,422$21,596,250 15.2%2,467,5912.4%COM
Alkermes plc stock logo
ALKS
Alkermes
$163,889,360$58,275,132 55.2%6,054,2802.4%Medical
Protagonist Therapeutics, Inc. stock logo
PTGX
Protagonist Therapeutics
$153,777,8200.0%5,315,5142.3%Medical
Penumbra, Inc. stock logo
PEN
Penumbra
$150,844,684$2,951,332 2.0%675,8882.2%Medical
Avadel Pharmaceuticals plc stock logo
AVDL
Avadel Pharmaceuticals
$148,607,645$31,257,310 26.6%8,798,5582.2%Medical
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
$137,211,941$46,458,849 51.2%5,431,9852.0%Medical
Establishment Labs Holdings Inc. stock logo
ESTA
Establishment Labs
$136,193,283$9,241,659 7.3%2,675,7032.0%Medical
Arvinas, Inc. stock logo
ARVN
Arvinas
$136,137,188$37,795,390 -21.7%3,297,8972.0%Medical
Tarsus Pharmaceuticals, Inc. stock logo
TARS
Tarsus Pharmaceuticals
$118,949,595$4,362,000 3.8%3,272,3411.8%Medical
Stryker Co. stock logo
SYK
Stryker
$114,876,270$114,876,270 New Holding321,0001.7%Medical
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
$106,027,431$111,661,174 -51.3%397,0471.6%Medical
Immatics stock logo
IMTX
Immatics
$105,100,000$89,493,585 573.4%10,000,0001.6%Medical
Sage Therapeutics, Inc. stock logo
SAGE
Sage Therapeutics
$102,706,013$5,313,877 5.5%5,480,5771.5%Medical
Shockwave Medical, Inc. stock logo
SWAV
Shockwave Medical
$94,004,171$72,818,683 343.7%288,6841.4%Medical
DYNE THERAPEUTICS INC
$87,770,155$87,770,155 New Holding3,091,5871.3%COM
89bio, Inc. stock logo
ETNB
89bio
$85,886,299$20,947,542 32.3%7,378,5481.3%Medical
SPYRE THERAPEUTICS INC
$84,688,5860.0%2,232,7601.3%COM NEW
Vericel Co. stock logo
VCEL
Vericel
$83,564,772$83,564,772 -50.0%1,606,3971.2%Medical
CARGO THERAPEUTICS INC
$83,379,016$32,145,554 -27.8%3,735,6191.2%COM
RadNet, Inc. stock logo
RDNT
RadNet
$82,748,763$50,457,890 156.3%1,700,5501.2%Medical
Thermo Fisher Scientific Inc. stock logo
TMO
Thermo Fisher Scientific
$64,223,705$35,163,205 121.0%110,5000.9%Medical
10x Genomics, Inc. stock logo
TXG
10x Genomics
$58,353,746$184,085 0.3%1,554,8560.9%Medical
Stoke Therapeutics, Inc. stock logo
STOK
Stoke Therapeutics
$57,035,313$1,266,206 2.3%4,224,8380.8%Medical
Fulcrum Therapeutics, Inc. stock logo
FULC
Fulcrum Therapeutics
$55,185,825$3,549,440 6.9%5,845,9560.8%Medical
Taysha Gene Therapies, Inc. stock logo
TSHA
Taysha Gene Therapies
$53,362,441$4,879,000 10.1%18,593,1850.8%Medical
Insmed Incorporated stock logo
INSM
Insmed
$50,600,3800.0%1,865,1080.7%Medical
UroGen Pharma Ltd. stock logo
URGN
UroGen Pharma
$48,860,205$22,958,085 88.6%3,257,3470.7%Medical
KYVERNA THERAPEUTICS INC
$46,021,341$46,021,341 New Holding1,852,7110.7%COM
Intuitive Surgical, Inc. stock logo
ISRG
Intuitive Surgical
$39,509,910$39,509,910 New Holding99,0000.6%Medical
NEUROGENE INC
$39,148,310$39,148,310 New Holding769,1220.6%COM
Janux Therapeutics, Inc. stock logo
JANX
Janux Therapeutics
$37,650,000$37,650,000 New Holding1,000,0000.6%Medical
GH Research PLC stock logo
GHRS
GH Research
$35,467,1950.0%3,327,1290.5%Medical
Orchestra BioMed Holdings, Inc. stock logo
OBIO
Orchestra BioMed
$29,620,7730.0%5,620,6400.4%Medical
DIANTHUS THERAPEUTICS INC
$20,000,010$20,000,010 New Holding666,6670.3%COM
ESSA Pharma Inc. stock logo
EPIX
ESSA Pharma
$19,515,6400.0%2,298,6620.3%Medical
LENZ THERAPEUTICS INC
$19,279,476$19,279,476 New Holding863,3890.3%COM
CG ONCOLOGY INC
$18,160,113$18,160,113 New Holding413,6700.3%COM
TOURMALINE BIO INC
$16,983,922$7,850,257 85.9%741,6560.3%COM
Roivant Sciences Ltd. stock logo
ROIV
Roivant Sciences
$15,328,0370.0%1,454,2730.2%Medical
Viridian Therapeutics, Inc. stock logo
VRDN
Viridian Therapeutics
$10,607,8380.0%605,8160.2%Medical
Adicet Bio, Inc. stock logo
ACET
Adicet Bio
$9,716,3830.0%4,134,6310.1%Medical
REGENXBIO Inc. stock logo
RGNX
REGENXBIO
$7,374,500$7,374,500 New Holding350,0000.1%Medical
Acelyrin, Inc. stock logo
SLRN
Acelyrin
$6,603,5930.0%978,3100.1%Medical
Exact Sciences Co. stock logo
EXAS
Exact Sciences
$6,560,700$6,560,700 New Holding95,0000.1%Medical
ALLURION TECHNOLOGIES INC
$6,050,9870.0%3,457,7070.1%COM SHS
Immunic, Inc. stock logo
IMUX
Immunic
$6,029,386$306,850 5.4%4,567,7170.1%Medical
Milestone Pharmaceuticals Inc. stock logo
MIST
Milestone Pharmaceuticals
$5,828,4230.0%3,256,1020.1%Medical
Glaukos Co. stock logo
GKOS
Glaukos
$5,543,403$5,543,403 New Holding58,7910.1%Medical
SAGIMET BIOSCIENCES INC
$5,415,377$5,415,377 New Holding999,1470.1%COM SER A
Larimar Therapeutics, Inc. stock logo
LRMR
Larimar Therapeutics
$4,933,500$4,933,500 New Holding650,0000.1%Medical
SAB BIOTHERAPEUTICS INC
$4,166,934$4,166,934 New Holding917,8270.1%COM NEW
Exagen Inc. stock logo
XGN
Exagen
$2,392,3170.0%1,504,6020.0%Medical
Beyond Air, Inc. stock logo
XAIR
Beyond Air
$2,096,387$2,096,387 New Holding1,204,8200.0%Medical
Cutera, Inc. stock logo
CUTR
Cutera
$1,957,711$714,139 -26.7%1,331,7760.0%Computer and Technology
ARYA Sciences Acquisition Corp IV stock logo
ARYD
ARYA Sciences Acquisition Corp IV
$1,437,1030.0%127,9700.0%Medical
Rocket Pharmaceuticals, Inc. stock logo
RCKTW
Rocket Pharmaceuticals
$104,7200.0%350,0000.0%Medical
Mirati Therapeutics, Inc. stock logo
MRTX
Mirati Therapeutics
$0$397,650,198 -100.0%00.0%Medical
Alnylam Pharmaceuticals, Inc. stock logo
ALNY
Alnylam Pharmaceuticals
$0$314,019,398 -100.0%00.0%Medical
Celldex Therapeutics, Inc. stock logo
CLDX
Celldex Therapeutics
$0$137,350,552 -100.0%00.0%Medical
Danaher Co. stock logo
DHR
Danaher
$0$27,433,223 -100.0%00.0%Multi-Sector Conglomerates
SpringWorks Therapeutics, Inc. stock logo
SWTX
SpringWorks Therapeutics
$0$22,812,500 -100.0%00.0%Medical
Tango Therapeutics, Inc. stock logo
TNGX
Tango Therapeutics
$0$19,470,845 -100.0%00.0%Medical
Guardant Health, Inc. stock logo
GH
Guardant Health
$0$13,335,028 -100.0%00.0%Medical
SAB Biotherapeutics, Inc. stock logo
SABS
SAB Biotherapeutics
$0$6,310,069 -100.0%00.0%Medical
Apyx Medical Co. stock logo
APYX
Apyx Medical
$0$2,688,023 -100.0%00.0%Medical
Sight Sciences, Inc. stock logo
SGHT
Sight Sciences
$0$850,399 -100.0%00.0%Medical
Sientra, Inc. stock logo
SIEN
Sientra
$0$49,420 -100.0%00.0%Medical

Showing largest 100 holdings. View all holdings.

More Institutional Buying and Selling Information

SEC Filings and Trading Data: