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Silverarc Capital Management, LLC Top Holdings and 13F Report (2024)

About Silverarc Capital Management, LLC

Investment Activity

  • Silverarc Capital Management, LLC has $445.29 million in total holdings as of September 30, 2024.
  • Silverarc Capital Management, LLC owns shares of 71 different stocks, but just 29 companies or ETFs make up 80% of its holdings.
  • Approximately 18.78% of the portfolio was purchased this quarter.
  • About 23.31% of the portfolio was sold this quarter.
  • This quarter, Silverarc Capital Management, LLC has purchased 72 new stocks and bought additional shares in 27 stocks.
  • Silverarc Capital Management, LLC sold shares of 20 stocks and completely divested from 16 stocks this quarter.

Largest Holdings

Nuvalent
$37,998,414
Merus
$31,746,532
Insmed
$25,381,735
Erasca
$18,963,912

Largest New Holdings this Quarter

Centessa Pharmaceuticals
$11,906,026 Holding
Protagonist Therapeutics
$6,599,565 Holding
BioNTech
$3,097,878 Holding
Relay Therapeutics
$2,968,233 Holding
Zevra Therapeutics
$2,429,000 Holding

Largest Purchases this Quarter

Insmed
207,695 shares (about $15.16M)
Centessa Pharmaceuticals
744,592 shares (about $11.91M)
Vaxcyte
58,000 shares (about $6.63M)
Protagonist Therapeutics
146,657 shares (about $6.60M)
Veracyte
188,317 shares (about $6.41M)

Largest Sales this Quarter

Nuvalent
94,269 shares (about $9.64M)
Celldex Therapeutics
229,910 shares (about $7.81M)
C4 Therapeutics
1,292,841 shares (about $7.37M)
Mersana Therapeutics
2,332,285 shares (about $4.41M)
Corbus Pharmaceuticals
154,692 shares (about $3.19M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofSilverarc Capital Management, LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
Nuvalent, Inc. stock logo
NUVL
Nuvalent
$37,998,414$9,643,719 -20.2%371,4418.5%Medical
Merus stock logo
MRUS
Merus
$31,746,532$590,078 1.9%635,4397.1%Medical
Insmed Incorporated stock logo
INSM
Insmed
$25,381,735$15,161,735 148.4%347,6955.7%Medical
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
$21,842,241$1,937,281 -8.1%475,5554.9%Medical
Erasca, Inc. stock logo
ERAS
Erasca
$18,963,912$2,376,296 -11.1%6,946,4884.3%Medical
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
$18,357,010$423,264 2.4%639,8404.1%Medical
Veracyte, Inc. stock logo
VCYT
Veracyte
$16,018,033$6,410,311 66.7%470,5653.6%Medical
Rhythm Pharmaceuticals, Inc. stock logo
RYTM
Rhythm Pharmaceuticals
$13,389,731$3,715,289 38.4%255,5783.0%Medical
Cogent Biosciences, Inc. stock logo
COGT
Cogent Biosciences
$13,190,710$163,598 1.3%1,221,3623.0%Medical
Intra-Cellular Therapies, Inc. stock logo
ITCI
Intra-Cellular Therapies
$12,227,439$1,846,445 -13.1%167,1102.7%Medical
Centessa Pharmaceuticals plc stock logo
CNTA
Centessa Pharmaceuticals
$11,906,026$11,906,026 New Holding744,5922.7%Medical
UroGen Pharma Ltd. stock logo
URGN
UroGen Pharma
$11,444,338$2,551,062 -18.2%901,1292.6%Medical
ORIC Pharmaceuticals, Inc. stock logo
ORIC
ORIC Pharmaceuticals
$11,269,773$242,700 2.2%1,099,4902.5%Medical
Poseida Therapeutics, Inc. stock logo
PSTX
Poseida Therapeutics
$10,546,387$227,510 2.2%3,687,5482.4%Medical
Verona Pharma plc stock logo
VRNA
Verona Pharma
$10,036,875$1,272,583 14.5%348,8662.3%Medical
Alnylam Pharmaceuticals, Inc. stock logo
ALNY
Alnylam Pharmaceuticals
$9,838,923$62,157 -0.6%35,7742.2%Medical
Geron Co. stock logo
GERN
Geron
$8,179,087$3,642,401 80.3%1,801,5611.8%Medical
Syndax Pharmaceuticals, Inc. stock logo
SNDX
Syndax Pharmaceuticals
$7,290,861$168,361 2.4%378,7461.6%Medical
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$6,913,335$6,627,660 2,320.0%60,5001.6%Medical
KalVista Pharmaceuticals, Inc. stock logo
KALV
KalVista Pharmaceuticals
$6,653,382$158,357 2.4%574,5581.5%Medical
Protagonist Therapeutics, Inc. stock logo
PTGX
Protagonist Therapeutics
$6,599,565$6,599,565 New Holding146,6571.5%Medical
C4 Therapeutics, Inc. stock logo
CCCC
C4 Therapeutics
$6,542,979$1,681,215 -20.4%1,147,8911.5%Medical
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$6,399,988$1,154,608 22.0%51,2451.4%Medical
Biodesix, Inc. stock logo
BDSX
Biodesix
$6,338,747$3,118,800 96.9%3,561,0941.4%Medical
Elutia Inc. stock logo
ELUT
Elutia
$6,270,528$160,889 2.6%1,645,8081.4%Medical
ADC Therapeutics SA stock logo
ADCT
ADC Therapeutics
$5,654,502$82,877 1.5%1,795,0801.3%Medical
Gossamer Bio, Inc. stock logo
GOSS
Gossamer Bio
$5,568,575$143,375 2.6%5,645,3521.3%Medical
Olema Pharmaceuticals, Inc. stock logo
OLMA
Olema Pharmaceuticals
$5,433,679$1,095,865 -16.8%455,0821.2%Medical
HELIX ACQUISITION CORP II
$5,364,655$139,705 2.7%513,3691.2%CL A ORD SHS
ABIVAX SA
$5,318,323$67,507 1.3%461,6601.2%SPONSORED ADS
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
$5,145,926$1,083,064 26.7%627,5521.2%Medical
Disc Medicine, Inc. stock logo
IRON
Disc Medicine
$5,103,779$131,450 2.6%103,8621.1%Medical
Biohaven Ltd. stock logo
BHVN
Biohaven
$4,975,313$21,687 -0.4%99,5661.1%Medical
Celldex Therapeutics, Inc. stock logo
CLDX
Celldex Therapeutics
$4,928,550$7,814,641 -61.3%145,0001.1%Medical
Longboard Pharmaceuticals, Inc. stock logo
LBPH
Longboard Pharmaceuticals
$4,144,685$50,128 1.2%124,3530.9%Medical
Biogen Inc. stock logo
BIIB
Biogen
$3,865,170$111,458 3.0%19,9400.9%Medical
PRAXIS PRECISION MEDICINES I
$3,857,769$14,443 -0.4%67,0450.9%COM NEW
Modular Medical, Inc. stock logo
MODD
Modular Medical
$3,240,000$1,215,000 60.0%1,440,0000.7%Medical
Solid Biosciences Inc. stock logo
SLDB
Solid Biosciences
$3,190,441$106,334 -3.2%457,7390.7%Medical
BioNTech SE stock logo
BNTX
BioNTech
$3,097,878$3,097,878 New Holding26,0830.7%Medical
Structure Therapeutics Inc. stock logo
GPCR
Structure Therapeutics
$3,094,9470.0%70,5160.7%Medical
Mersana Therapeutics, Inc. stock logo
MRSN
Mersana Therapeutics
$2,997,136$1,728,970 -36.6%1,585,7860.7%Medical
Relay Therapeutics, Inc. stock logo
RLAY
Relay Therapeutics
$2,968,233$2,968,233 New Holding419,2420.7%Medical
TELA Bio, Inc. stock logo
TELA
TELA Bio
$2,846,068$316,068 12.5%1,124,9280.6%Medical
Compugen Ltd. stock logo
CGEN
Compugen
$2,717,0150.0%1,501,1130.6%Medical
Cerus Co. stock logo
CERS
Cerus
$2,601,872$51,478 2.0%1,495,3290.6%Medical
Zevra Therapeutics, Inc. stock logo
ZVRA
Zevra Therapeutics
$2,429,000$2,429,000 New Holding350,0000.5%Medical
PERSPECTIVE THERAPEUTICS INC
$2,242,613$1,228,507 -35.4%167,9860.5%COM NEW
BIOAGE LABS INC
$2,080,000$2,080,000 New Holding100,0000.5%COM
Unicycive Therapeutics, Inc. stock logo
UNCY
Unicycive Therapeutics
$1,631,600$1,631,600 New Holding4,000,0000.4%Medical
Trevi Therapeutics, Inc. stock logo
TRVI
Trevi Therapeutics
$1,611,801$1,207,945 -42.8%482,5750.4%Medical
Xencor, Inc. stock logo
XNCR
Xencor
$1,518,446$1,518,446 New Holding75,5070.3%Medical
Tarsus Pharmaceuticals, Inc. stock logo
TARS
Tarsus Pharmaceuticals
$1,315,6000.0%40,0000.3%Medical
Kodiak Sciences Inc. stock logo
KOD
Kodiak Sciences
$1,305,000$1,466,982 -52.9%500,0000.3%Medical
EVOGENE LTD
$945,480$945,480 New Holding307,9740.2%SHS NEW
MOLECULAR TEMPLATES INC
$876,4920.0%623,8380.2%COM NEW
C4 Therapeutics, Inc. stock logo
CCCC
C4 Therapeutics
$855,000$7,369,194 -89.6%150,0000.2%Medical
Applied Therapeutics, Inc. stock logo
APLT
Applied Therapeutics
$850,000$850,000 New Holding100,0000.2%Medical
Vaxart, Inc. stock logo
VXRT
Vaxart
$849,000$849,000 New Holding1,000,0000.2%Medical
EyePoint Pharmaceuticals, Inc. stock logo
EYPT
EyePoint Pharmaceuticals
$799,0000.0%100,0000.2%Medical
Ascendis Pharma A/S stock logo
ASND
Ascendis Pharma A/S
$746,550$746,550 New Holding5,0000.2%Medical
INSTIL BIO INC
$708,004$708,004 New Holding10,5170.2%COM NEW
89bio, Inc. stock logo
ETNB
89bio
$683,0050.0%92,2980.2%Medical
Karyopharm Therapeutics Inc. stock logo
KPTI
Karyopharm Therapeutics
$463,5270.0%558,4660.1%Medical
Black Diamond Therapeutics, Inc. stock logo
BDTX
Black Diamond Therapeutics
$435,000$435,000 New Holding100,0000.1%Medical
FRACTYL HEALTH INC
$421,6650.0%166,6660.1%COM
Corbus Pharmaceuticals Holdings, Inc. stock logo
CRBP
Corbus Pharmaceuticals
$367,214$3,191,296 -89.7%17,8000.1%Medical
Mersana Therapeutics, Inc. stock logo
MRSN
Mersana Therapeutics
$318,087$4,408,019 -93.3%168,3000.1%Medical
ALIGOS THERAPEUTICS INC
$227,057$227,057 New Holding26,2190.1%COM NEW
VYNE Therapeutics Inc. stock logo
VYNE
VYNE Therapeutics
$144,354$734,353 -83.6%76,7840.0%Medical
Rocket Pharmaceuticals, Inc. stock logo
RCKTW
Rocket Pharmaceuticals
$6,7610.0%104,8280.0%Medical
INSMED INC
$0$16,750,000 -100.0%00.0%CALL
Morphic Holding, Inc. stock logo
MORF
Morphic
$0$16,568,445 -100.0%00.0%Medical
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
$0$2,707,643 -100.0%00.0%Medical
JASPER THERAPEUTICS INC
$0$2,494,548 -100.0%00.0%COM NEW
ENGENE HOLDINGS INC
$0$2,488,021 -100.0%00.0%COM
Fulcrum Therapeutics, Inc. stock logo
FULC
Fulcrum Therapeutics
$0$2,470,303 -100.0%00.0%Medical
Evogene Ltd. stock logo
EVGN
Evogene
$0$2,003,062 -100.0%00.0%Medical
Stoke Therapeutics, Inc. stock logo
STOK
Stoke Therapeutics
$0$1,911,908 -100.0%00.0%Medical
MacroGenics, Inc. stock logo
MGNX
MacroGenics
$0$1,572,500 -100.0%00.0%Medical
Zura Bio Limited stock logo
ZURA
Zura Bio
$0$1,149,764 -100.0%00.0%Medical
ALX ONCOLOGY HLDGS INC
$0$1,012,437 -100.0%00.0%PUT
C4 THERAPEUTICS INC
$0$693,000 -100.0%00.0%CALL
Soleno Therapeutics, Inc. stock logo
SLNO
Soleno Therapeutics
$0$612,000 -100.0%00.0%Medical
MERSANA THERAPEUTICS INC
$0$338,283 -100.0%00.0%CALL
Relmada Therapeutics, Inc. stock logo
RLMD
Relmada Therapeutics
$0$298,137 -100.0%00.0%Medical
Aligos Therapeutics, Inc. stock logo
ALGS
Aligos Therapeutics
$0$229,430 -100.0%00.0%Medical

Showing largest 100 holdings. View all holdings.
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