Tcg Crossover Management, LLC Top Holdings and 13F Report (2025) About Tcg Crossover Management, LLCInvestment ActivityTcg Crossover Management, LLC has $1.02 billion in total holdings as of December 31, 2024.Tcg Crossover Management, LLC owns shares of 38 different stocks, but just 21 companies or ETFs make up 80% of its holdings.Approximately 17.51% of the portfolio was purchased this quarter.About 7.02% of the portfolio was sold this quarter.This quarter, Tcg Crossover Management, LLC has purchased 36 new stocks and bought additional shares in 4 stocks.Tcg Crossover Management, LLC sold shares of 2 stocks and completely divested from 3 stocks this quarter.Largest Holdings CG ONCOLOGY INC $105,261,508DYNE THERAPEUTICS INC $62,437,534Xencor $56,350,131Cogent Biosciences $54,322,125Centessa Pharmaceuticals $48,421,168 Largest New Holdings this Quarter UPSTREAM BIO INC $44,856,331 HoldingTango Therapeutics $33,174,240 HoldingDIANTHUS THERAPEUTICS INC $32,735,403 HoldingCidara Therapeutics, Inc. $26,092,267 HoldingRAPT Therapeutics $19,750,615 Holding Largest Purchases this Quarter UPSTREAM BIO INC 2,801,763 shares (about $44.86M)Tango Therapeutics 10,736,000 shares (about $33.17M)DIANTHUS THERAPEUTICS INC 1,501,624 shares (about $32.74M)Cidara Therapeutics, Inc. 1,005,901 shares (about $26.09M)RAPT Therapeutics 13,135,260 shares (about $19.75M) Largest Sales this Quarter Keros Therapeutics 329,344 shares (about $5.21M)ADVERUM BIOTECHNOLOGIES INC 211,857 shares (about $989.37K) Sector Allocation Over TimeMap of 500 Largest Holdings ofTcg Crossover Management, LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorCG ONCOLOGY INC$105,261,5080.0%3,670,20610.3%COMMDYNE THERAPEUTICS INC$62,437,5340.0%2,650,1506.1%COMMXNCRXencor$56,350,131$574,500 ▲1.0%2,452,1385.5%MedicalCOGTCogent Biosciences$54,322,1250.0%6,964,3755.3%MedicalCNTACentessa Pharmaceuticals$48,421,1680.0%2,890,8164.7%MedicalOCULOcular Therapeutix$45,425,5240.0%5,319,1484.4%MedicalUPSTREAM BIO INC$44,856,331$44,856,331 ▲New Holding2,801,7634.4%COMMABIVAX SA AMERICAN DEPOSITARY SHARES$44,334,2830.0%6,056,5964.3%ADRSSVRASavara$37,951,9690.0%12,362,2053.7%MedicalTNGXTango Therapeutics$33,174,240$33,174,240 ▲New Holding10,736,0003.2%MedicalDIANTHUS THERAPEUTICS INC$32,735,403$32,735,403 ▲New Holding1,501,6243.2%COMMIRONDisc Medicine$30,873,0740.0%486,9573.0%MedicalMLYSMineralys Therapeutics$30,408,9620.0%2,470,2653.0%MedicalTOURMALINE BIO INC$29,965,5860.0%1,477,5932.9%COMMGPCRStructure Therapeutics$28,828,5600.0%1,063,0002.8%MedicalTYRATyra Biosciences$27,648,5320.0%1,989,1032.7%MedicalEYPTEyePoint Pharmaceuticals$26,613,896$19,742,500 ▲287.3%3,572,3352.6%MedicalCidara Therapeutics, Inc.$26,092,267$26,092,267 ▲New Holding1,005,9012.5%COMMTHRDTF Financial$25,780,813$930,463 ▲3.7%2,505,4242.5%MedicalSLNOSoleno Therapeutics$24,722,5000.0%550,0002.4%MedicalATXSAstria Therapeutics$24,691,0370.0%2,761,8612.4%MedicalFULCFulcrum Therapeutics$24,675,0000.0%5,250,0002.4%MedicalSLNSilence Therapeutics$20,870,8930.0%3,033,5602.0%MedicalRAPTRAPT Therapeutics$19,750,615$19,750,615 ▲New Holding13,135,2601.9%MedicalAMLXAmylyx Pharmaceuticals$17,553,6090.0%4,643,8121.7%MedicalCMPSCOMPASS Pathways$14,583,2400.0%3,858,0001.4%MedicalKURAKura Oncology$12,399,9220.0%1,423,6421.2%MedicalMBX BIOSCIENCES INC$11,979,5000.0%650,0001.2%COMMKODKodiak Sciences$11,398,103$1,366,931 ▲13.6%1,145,5381.1%MedicalTRDAEntrada Therapeutics$10,113,8720.0%584,9551.0%MedicalKROSKeros Therapeutics$8,706,500$5,213,516 ▼-37.5%550,0000.9%MedicalADVERUM BIOTECHNOLOGIES INC$8,389,571$989,372 ▼-10.5%1,796,4820.8%COMMVTGNVistagen Therapeutics$7,895,9110.0%2,676,5800.8%MedicalAVTEAerovate Therapeutics$5,938,1440.0%2,240,8090.6%MedicalNKTRNektar Therapeutics$3,720,0000.0%4,000,0000.4%MedicalAVALO THERAPEUTICS INC$3,588,6900.0%483,0000.4%COMMVTYXVentyx Biosciences$692,4670.0%316,1950.1%MedicalCABACabaletta Bio$197,0250.0%86,7950.0%MedicalEWTXEdgewise Therapeutics$0$56,395,543 ▼-100.0%00.0%MedicalTARSTarsus Pharmaceuticals$0$7,624,560 ▼-100.0%00.0%MedicalANTX(ANTX)$0$1,663,976 ▼-100.0%00.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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