Shawn Vadala
Chief Financial Officer at Mettler-Toledo International
Thanks, Patrick. And good evening everyone. Sales in the quarter were $1.037 billion. This represents our first billion dollar quarter, which was a nice way to end 2021. This represented a local currency increase of 11%. On a US dollar basis, sales also increased 11%.
The PendoTECH acquisition contributed approximately 1% to local currency sales growth in the quarter, while we estimate that the impact of reduced volume of pipette tips in COVID testing was a headwind of approximately 1% to sales growth in the fourth quarter.
On slide number 4, we show sales growth by region. Local currency sales increased 16% in the Americas, 4% in Europe, and 14% in Asia-Rest of the World. Local currency sales increased 12% in China in the fourth quarter.
The next slide shows sales growth by region for the full year 2021. Local currency sales grew 18% in 2021, with a 20% increase in the Americas, 12% in Europe and 21% growth in Asia-Rest of World. Local currency sales increased 25% in China for the full year.
On slide number 6, we summarize local currency sales growth by product area. For the fourth quarter, laboratory sales increased 15%, industrial increased 11%, with core industrial up 11% and product inspection up 10%. Food retail declined 20% in the quarter.
The next slide shows local currency sales growth by product area for the full year 2021. Laboratory sales increased 22%, industrial increased 15%, with core industrial up 18% and product inspection up 10%. Food retail declined 6% in 2021.
Let me now move to the rest of the P&L for the fourth quarter, which is summarized on slide number 8. Gross margin in the quarter was 58.5%. We benefited from volume and pricing, which was offset by challenges in the global supply chain, namely higher material and transportation costs, as well as the impact of temporary cost actions we undertook in 2020.
R&D amounted to $45.6 million in the quarter, which is a 14% increase in local currency over the prior period. The impact of temporary cost savings undertaken last year and greater project activity contributed to this increase.
SG&A amounted to $242.4 million, an 8% increase in local currency over the prior year. The impact of the temporary cost savings that we undertook last year, higher variable compensation and increased investments in sales and marketing were the principal factors driving the increase.
Adjusted operating profit amounted to $319.1 million in the quarter, a 9% increase over the prior-year amount of $292.8 million. The increase reflects strong sales growth combined with good execution.
Adjusted operating margins were 30.8% and were impacted by higher costs associated with our global supply chain and transportation costs.
A couple of final comments on the P&L. Amortization amounted to $16.9 million in the quarter, interest expense was $11.5 million in the quarter. Other income, excluding one-time items in the quarter, amounted to $5.3 million, primarily reflecting non-service related pension income.
We reduced our effective tax rate from 19.5% to 19.0% in the quarter. This rate is before discrete items and adjusting for the timing of stock option exercises in the quarter. We are pleased with this reduction and expect to maintain the 19% rate in 2022.
Fully diluted shares amounted to 23.2 million in the quarter, which is a 3% decline from the prior year. Adjusted EPS for the quarter was $10.53, a 14% increase over the prior year amount of $9.26. On a reported basis, in the quarter, EPS was $9.94 as compared to $9.03 in the prior year. Reported EPS in the quarter includes $0.21 of purchased intangible amortization and $0.09 of restructuring.
We also had two items impacting income taxes. We had $0.17 of costs due to the difference between our quarterly and annual tax rate due to the timing of stock option exercises and we had a $0.14 benefit from adjusting our tax rate to 19% for the first three quarters. Finally, we had a $0.26 acquisition charge, principally reflecting an increase for the PendoTECH acquisition earn-out due to their updated projections.
The next slide shows our P&L year-to-date. As Patrick mentioned, we had an exceptional year of results in 2021 with local currency sales growth of 18%, an adjusted operating profit increase of 26%, and our operating margins increasing 130 basis points to 28.5%.
Finally, adjusted EPS grew 32% to $34.01 in 2021.
We are extremely pleased with these results and our ability to capitalize on growth opportunities and navigate a challenging supply chain environment.
That covers the P&L. And let me now comment on cash flow. In the quarter, adjusted free cash flow amounted to $206.6 million, which was better than what we had expected and was impacted by the timing of tax payments.
DSOs showed further improvement in the quarter, with a decline of 2 days to 35 days as compared to the prior year. ITO came in at 4.3 times, flat with the prior year.
For the full year, adjusted free cash flow amounted to $821.9 million, an increase of 31% on a per share basis, as compared to the prior year. The strength of our cash flow is apparent in our net income conversion, which reached 103% in 2021.
Let me now turn to guidance. Forecasting remains challenging. Demand in our end markets is favorable, although there are pockets of uncertainty in the global economy, particularly in China. The challenges within the global supply chain and in transportation and logistics and the corresponding inflationary impact also creates uncertainty.
Finally, we acknowledge that COVID is not behind us and variants and lockdowns can occur quickly. We recognize the importance of remaining agile and adapting to unexpected changes in the environment.
We remain cautious about factors outside of our control and remain focused on our growth initiatives. We believe we can continue to gain market share and drive margin improvement via our pricing and SternDrive initiatives.
Now let me cover the specifics. For the full year 2022, we now expect local currency sales growth to be approximately 7%. This compares to previous guidance of 6%. We expect full-year adjusted EPS to be in the range of $38.15 to $38.50, which is a growth rate of 12% to 13%. This compares to previous guidance of adjusted EPS in the range of $37.25 to $37.65.
Some additional comments on 2022 guidance. We expect a slight headwind to sales growth from the impact of COVID testing on our pipette business. We expect gross margins for the full year to increase in the 30 to 40 basis point range. However, we expect to see improvement in gross margins in the second half of the year as we see further benefit in pricing and other margin initiatives.
Interest expense is estimated at approximately $50 million and total amortization, including purchased intangible amortization, to be $67 million. Purchased intangible amortization is excluded from adjusted EPS and is estimated at $25 million on a pre-tax or $0.86 per share.
Other income, which is below operating profit, is estimated at approximately $14 million.
Finally, as I already mentioned, we expect our effective annual tax rate before discrete items will be 19%.
Turning to the first quarter, based on market conditions today, we expect local currency sales growth of approximately 10% and expect adjusted EPS to be in the range of $7.25 to $7.35, a growth rate of 11% to 12%.
A couple of further comments. A reminder that comparisons in the first quarter are particularly challenging as adjusted EPS grew more than 60% in Q1 last year. We would expect gross margins to be down in Q1 due to higher supply chain and transportation costs. We will provide more insight on our next call, but it is worth mentioning now as you update your models that Q2 will have a very tough prior-year comparison as local currency sales were up 27% and adjusted EPS increased more than 50% in the second quarter of last year.
Some final details on guidance. With respect to the impact of currency on sales growth, we expect currency to decrease sales growth by approximately 1% in 2022 and decrease it by 2% in Q1.
In terms of adjusted EPS, currency is a little worse than the last time we provided guidance. We now expect currency will be a headwind to adjusted EPS growth of approximately 1% in 2022 and a headwind of approximately 2% in the first quarter.
Let me comment on free cash flow. For the full-year 2022, we estimate it will reach $855 million. As we mentioned on our last call, our cash flow this year is impacted by higher variable compensation payments related to the very strong performance in 2021. In fact, we expect cash flow in Q1 to be down versus the prior year. Once we get beyond 2022, we expect free cash flow per share will grow in line with earnings per share and net income conversion will be in the 100% range.
We expect to repurchase approximately $1 billion in shares in 2022, which should allow us to maintain a net debt to EBITDA leverage ratio of approximately 1.5 times.
That is it from my side, and I'll now turn it back to Patrick.