NYSE:RVTY Revvity Q4 2023 Earnings Report Earnings HistoryForecast Atlantica Sustainable Infrastructure EPS ResultsActual EPS$1.25Consensus EPS $1.15Beat/MissBeat by +$0.10One Year Ago EPSN/AAtlantica Sustainable Infrastructure Revenue ResultsActual Revenue$695.90 millionExpected RevenueN/ABeat/MissN/AYoY Revenue GrowthN/AAtlantica Sustainable Infrastructure Announcement DetailsQuarterQ4 2023Date2/1/2024TimeN/AConference Call DateThursday, February 1, 2024Conference Call Time8:00AM ETUpcoming EarningsRevvity's Q1 2025 earnings is scheduled for Monday, April 28, 2025, with a conference call scheduled at 8:00 AM ET. Check back for transcripts, audio, and key financial metrics as they become available.Q1 2025 Earnings ReportConference Call ResourcesConference Call AudioConference Call TranscriptSlide DeckPress Release (8-K)Annual Report (10-K)Earnings HistoryCompany ProfileSlide DeckFull Screen Slide DeckPowered by Revvity Q4 2023 Earnings Call TranscriptProvided by QuartrFebruary 1, 2024 ShareLink copied to clipboard.There are 14 speakers on the call. Operator00:00:00Hello, and welcome to today's MeVity, Inc. Q4 2023 Earnings Conference Call. My name is Bailey, and I will be the moderator for today's call. I'd now like to pass the conference over to our host today, Steve Willoughby, Senior Vice President of Investor Relations. Please go ahead. Speaker 100:00:28Thank you, operator. Good morning, everyone, and welcome to Remedy's Q4 2023 Earnings conference call. On the call with me today are Prahlad Singh, our President and Chief Executive Officer and Max Grecowiak, our Senior Vice President and Chief Financial Officer. Before we begin, I'd like to remind everyone of the Safe Harbor statement we have outlined in our press release issued earlier this morning and also those in our SEC filings. Statements or comments made on this call may be forward looking statements, which may include, but are not necessarily limited to, financial projections or other statements of the company's plans, objectives, expectations or intentions. Speaker 100:01:07These matters involve certain risks and uncertainties. The company's actual results may differ significantly from those projected or suggested due to a variety of factors, which are discussed in detail in our SEC filings. Any forward looking statements made today represent our views as of today. We disclaim any obligation to update these forward looking statements in the future, even if our estimates change. So you should not rely on any of today's statements as representing views as of any date after today. Speaker 100:01:36During this call, we will be referring to certain non GAAP financial measures. A reconciliation of the non GAAP financial measures we plan to use during this call to the most directly comparable GAAP measures is available as an attachment to our earnings press release. I'll now turn it over to our President and Chief Executive Officer, Prahlad Singh. Prahlad? Speaker 200:01:56Thank you, Steve, and good morning, everyone. As we highlighted in our pre announcement a few weeks ago, while industry headwinds continued throughout the end of the year, We were able to perform slightly better than we had anticipated and finished the 4th quarter with a 3% decline in non COVID organic revenue. While Max will provide more details on the quarter in a bit, I would say that our Stronger than anticipated results were broad based as both our Life Sciences and Diagnostics segments performed better than expected. I would also highlight that our performance was well balanced geographically as each major region performed in line to slightly above what we had assumed. We also did a good job continuing to tightly control our expenses in light of the challenging environment that persisted through year end. Speaker 200:02:57And along with some favorable one time tax benefits helped deliver additional EPS upside in the 4th quarter. We also had a very strong cash flow in the quarter with nearly $200,000,000 of free cash flow while continuing to execute on our capital deployment initiatives. For the full year 2023, we generated 2% non COVID organic growth. While not what we hoped for at the start of the year, I think you will see that our performance was differentiated versus the broader industry and likely will be near the high end of the peer set for the year once the dust fully settles. We expect this differentiated financial performance to continue going forward. Speaker 200:03:52As demonstrated in the new financial framework, We recently provided for our expected performance over the coming years. As part of this new long range outlook, We now expect Reviti's organic revenue growth to be 200 basis points above the broader industry regardless of the macro environment. In a normal year, we would expect this to result in 6% to 8% organic growth and seventy basis points of operating margin expansion annually. In the post COVID world we all now operate in, We anticipate this level of growth will result in performance that continues to be at the high end of our industry overall. As we highlighted during a recent investor conference, we expect approximately 60% of our business that is comprised of immunodiagnostics, life sciences reagents and our signal software business to grow in the 9% to 11% range over the coming years, generating mid single digit growth on their own for the total company. Speaker 200:05:05Given the stronger profitability of these segments, as they continue to grow faster than the remainder of the business, We expect it to result in natural margin expansion as they become an increasingly larger piece of the overall company over time. Reviti is extremely well positioned to capitalize on some of the most exciting areas of pharmaceutical research and development such as cell and gene therapy, multiomics and precision medicine. We are also involved in some of the most durable higher growth areas within clinical diagnostics such as autoimmunity, tuberculosis and other emerging infectious diseases. With what our company has become over the last several years and where we are planning on going in the future, I think you will see that Reviti will continue to stand out as a very unique company. We have a differentiated approach with our customers, our competitive and novel product portfolio with continuous innovation and a unique position within the attractive life sciences and diagnostic categories in which we compete. Speaker 200:06:26A good example of this in the Q4 was the launch of our Ionis Q system in our newborn screening business. The Ionis Q system is a first of its kind workflow which streamlines molecular testing for both spinal muscular atrophy and SKIT in newborns. It is a new and complete CEIVD solution This consists of a new PEAP CR equipment with dedicated software and a specialized diagnostics kit. With no watch steps being needed in the new workflow, it results in a significantly faster turnaround time and less hands on involvement from sample to answer than existing methods. This allows for lower operating costs greater sustainability as fewer consumables and plasticware are required. Speaker 200:07:22The introduction of this Innovative solution is also perfectly timed from a commercial perspective. As the European Alliance for Newborn Screening and Spinal muscular atrophy mandates that by 2025, all newborns in Europe should be screened for SMA going forward. Our new Ionis Q system is just one example of how we are continuing to bring Cutting edge and innovative solutions to market from across the company benefiting both our customers and ultimately the patients they serve. We have also been making good progress on our operational initiatives. A good example of this is the launch of our new e commerce platform which went live in the U. Speaker 200:08:14S. In mid December approximately 5 to 6 months earlier than we anticipated. The platform's integrated design was built Specifically for the needs of what our business has become. It is expected to be extremely consumer friendly while also over time delivering both revenue and operating synergies. We expect this new system to go live outside the U. Speaker 200:08:42S. In early 2Q. Another thing I'm extremely proud See is the strong collaboration that is occurring amongst our teams across the company. A great example of this was how last year we had a sole source antibody supplier for one of our diagnostics assays begin to have quality inconsistencies in their batches. Through the rapid collaboration amongst scientists from Euroimmune, Biolegend and Horizon, Within 9 weeks, we had developed our own replacement antibody, validated it and were able to manufacture it in sufficient scale for commercial use. Speaker 200:09:28The ability and agility would never have been possible in the company of the past And I'm not sure it would be possible at most companies today other than Reviti. As we look ahead to this year, we expect the ongoing headwinds from our pharma and biotech customers to continue, particularly in the first half of the year as they still are working through the impact from their elevated spending levels during the COVID years. We are assuming this pressure will begin to stabilize in the back half of the year when we anticipating returning to growth for the company overall. In light of the dynamic end market challenges continuing into 2020 4, as well as the return of some of the variable costs that we reduced in 2023, We have recently implemented additional structural cost actions to protect our strong profitability through this temporary period. We anticipate these actions will allow for our operating margins to remain approximately flat year over year at 28% this year. Speaker 200:10:42Despite the low single digit organic growth, we expect to repeat into 2024. We expect This to result in our 2024 adjusted EPS to be in the range of $4.55 to $4.75 With our significant number of acquisitions over the past several years, Coupled with the large divestiture we completed in early 2023, we still have many areas to further in order to reach our full potential as a company. The significant actions we took in 2023 Combined with the additional measures being implemented as we begin 2024 have put us on a good trajectory to further streamline and adjust our operations for the business we have now become. It also strongly positions us to capitalize on the leverage potential that exists in our company once industry growth normalizes. Overall, when looking back on 2023, I'd say it certainly ended up playing out quite differently than we had anticipated when sitting here a year ago. Speaker 200:12:01However, I'm so proud of the transformation that we have undergone over the past few years, which we ultimately completed last year. While we are continuing to face external challenges, I'm extremely grateful for what Reviti has become and the significant efforts of so many who have made it come to fruition. Without everyone's efforts and the rebirth of the company, our differentiated performance in 2023 would not have been possible. We remain confident that we will emerge from this temporary period of industry headwinds as a unique and stronger company that remains well positioned to help expand the boundaries of human potential through science. With that, I'll now turn the call over to Max. Speaker 300:13:00Thanks, Prahlad, and good morning, everyone. The company demonstrated its perseverance in the Q4 during a period in which underlying industry demand continued to remain dynamic. I am proud of our team's performance despite these challenges continuing through year end, allowing our results to exceed our expectations for the quarter. As I'll comment on more in a bit, we are now assuming the current market environment remains largely in place through at least the first half of this year, which will continue to put pressure on our results and cause our full year expectations to look fairly similar to what we achieved in 2023. However, we would expect our performance to be somewhat of the inverse of what we saw last year with the first half of twenty twenty four remaining challenged and facing organic revenue declines before returning to growth in the second half. Speaker 300:13:55While we work through this dynamic period, We have continued to remain extremely focused on those items and actions that are more fully within our control. We progressively tightened our expense management efforts throughout last year. And as previously mentioned, we have already implemented significant additional structural cost measures So far this year, which we anticipate will allow our operating margins to remain flat at 28% this year, despite our low single digit growth outlook paving the way for greater operating leverage in the future when growth normalizes. We also made good progress with our balance sheet and cash flow in 2023. In the Q4, we generated $196,000,000 of free cash flow as we made meaningful progress on collections and inventory management. Speaker 300:14:43Excluding the divestiture related outflows we incurred during the year, much of which will be coming back to us in 2024, we generated over $400,000,000 of free cash flow in 2023 overall. Given the amount of change that has occurred at the company over the past year, I view this as very strong performance and we are well to continue executing on our capital deployment initiatives this year. Now moving to our specific Q4 and full year results. Overall, the company generated total adjusted revenues of $696,000,000 in the quarter, resulting in a 3% decline in non COVID organic revenue, which was above the high end of our guidance. The outperformance was fairly broad based as both our Life Sciences and our Diagnostics segments performed slightly above our expectations for the quarter. Speaker 300:15:35FX was a 1% tailwind and we again had no incremental contribution from acquisitions. For the full year, we generated $2,750,000,000 of total adjusted revenue, which was comprised of 2% non COVID organic growth, No impact from FX or M and A and a modest $3,000,000 contribution early in the year from COVID. As it relates to our P and L, we generated 27.5 percent adjusted operating margins in the quarter, which were in line with our expectations. For the full year, our op margins were 28%, which represented approximately 100 basis points of expansion excluding the removal of related revenues. We incurred a favorable pricing impact of approximately 130 basis points in the quarter, which brought the full year impact from pricing to approximately 150 basis points. Speaker 300:16:30We continue to expect at least 100 basis points of favorable pricing annually going forward. Looking below the line, we had adjusted net interest and other expense of $16,000,000 which was largely in line with our expectations. For the full year, our adjusted net interest and other expense was 58,000,000 Our adjusted tax rate was 12% in the quarter, which was favorable by a few 100 basis points to our expectations due to a couple of onetime tax items. These favorable discrete tax items contributed approximately $0.05 to our EPS in the quarter. For the full year, our adjusted tax rate was 18.6%, but would have been approximately 20% and in line with our expectations, Excluding the favorability we incurred here in the 4th quarter, which we do not expect to repeat in the future. Speaker 300:17:22We averaged 123,400,000 shares outstanding in the quarter and 124,800,000 for the full year. This all led to adjusted EPS in the Q4 of $1.25 which was $0.09 above the midpoint and $0.07 above the high end of our expectations. Our full year 2023 adjusted EPS was $4.65 Moving beyond the P and L, As I mentioned, we generated free cash flow of $196,000,000 in the quarter, while on a full year basis, our free cash flow was $198,000,000 which includes a headwind of slightly over $200,000,000 from one time divestiture and rebranding related activities. Also, as I previously mentioned, we expect a large portion of these outflows to reverse in 2024 and positively impact our investing cash flows when they come back to us. As for capital deployment, we continue to remain active in the 4th quarter. Speaker 300:18:22We purchased an additional $400,000,000 of U. S. Treasuries with maturities aligned to the remainder of the $800,000,000 bond we have coming due in September. We now have over $700,000,000 of treasuries on our balance sheet, which will mature shortly before our bond comes due this September that we will use to extinguish this debt. We finished the quarter with a net debt to adjusted EBITDA leverage ratio of 2.8 times. Speaker 300:18:48I will now provide some commentary on our 4th quarter and full year business trends, which is also included in the quarterly slide presentation on our Investor Relations website. The 3% decline in non COVID organic revenue in the quarter was comprised of a 9% decline in our Life Sciences segment and 3% growth in Diagnostics. Geographically, we declined in high single digits in the Americas declined in the low single digits in Europe and grew low single digits in Asia with China flat overall. For the full year, we achieved 2% non COVID organic growth with 5% growth in diagnostics and flat performance in life sciences. The Americas declined low single digits, Europe grew mid single digits and both Asia and China grew mid single digits for the full year. Speaker 300:19:43Within China in the quarter, we experienced mid single digit growth in diagnostics with high single digit growth in immunodiagnostics, offset by a high single digit decline in life sciences. For the full year, China grew in the mid single digits organically with high single digit growth in diagnostics overall, low double digit growth in immunodiagnostics and mid single digit growth in life sciences. From a segment perspective, our Life Science business generated total adjusted revenue of $320,000,000 in the quarter. This was down 8% on a reported basis and 9% on an organic basis. For the full year, our Life Sciences business was flat organically. Speaker 300:20:27From a customer perspective, sales into pharma biotech customers declined in the mid teens in the quarter and in the mid single digits for the year, which was offset by high single digit growth from academic and government customers in the quarter and mid teens growth for the year. Our life sciences instrument revenue represented about 30% of total life science revenue in 2023 and was down high teens in the quarter and down in the mid single digits for the year. Our reagent licensing and specialty pharma services revenue represented 57% of Life Sciences revenue in 2023 and grew low single digits in the quarter and in the mid single digits for the year. Finally, our signal software business, which represented the remaining 13% of life science revenue in 2023, declined double digits in the quarter and in the high single digits for the year. The decline in both the quarter and the full year was in line with expectations and was driven by fewer multiyear contracts renewing, which we anticipate to normalize in 2024. Speaker 300:21:34In our Diagnostics segment, we generated $376,000,000 of total adjusted revenue in the quarter, which was down 4% on a reported basis and 6% on an organic basis. On a non COVID basis, the segment grew 3% versus a year ago in the quarter and 5% for the year. Our immunodiagnostics business represented about 50% of our total diagnostics revenue in 2023 and grew in the mid teens organically excluding COVID during both the quarter and the full year. Our immunodiagnostics business was strong globally as it continued to grow in the high teens outside of China, both in the quarter and the full year. Our reproductive health business, which represented about 34% of total diagnostics revenue in 2023, decline in the low single digits organically in the quarter and the full year. Speaker 300:22:27This business was again pressured by a significant mid 20% decline in our revenue omics lab business in the quarter and nearly 35% decline for the full year. As we transition to 2024, we will have now lapped the contract completions which pressured growth last year and do not anticipate such major year over year declines to continue. These pressures were partially offset by strong performance in 23 from our newborn franchise, which grew in the high single digits overall for the year. Finally, our Applied Genomics business, which represented the remaining roughly 16% of total diagnostics revenue in 2023, continued to see pressure from the slowdown in pharma biotech spending and the hangover effect from elevated clinical lab COVID spending. Non COVID organic revenue for our Applied Genomics business was down in the mid teens during the quarter and was down in the high single digits for the full year. Speaker 300:23:25Now as it pertains to our outlook for 2024, We expect current industry headwinds to remain over at least the next couple of quarters before we begin to face easier comparisons as the year progresses. Our initial guidance for organic growth is similar to what we experienced in 2023 in the 1% to 3% range. From a quarterly pacing perspective, we expect revenue in the Q1 to be down mid single digits with sequential improvement in the second quarter, resulting in the first half still being down year over year overall. We expect to return to positive growth starting in the Q3 this year. We also expect FX to contribute approximately 1% to total revenue based on the rates at the end of December. Speaker 300:24:11Moving down the P and L, we expect to hold our operating margins flat at 28% as our recent structural cost actions will help offset both some variable cost returning and the lower than normal organic growth we expect for this year. We expect total revenue in the Q1 to be the lowest of the year, which when combined with the only partial quarter impact from our recent cost actions, We expect it will result in our operating margins being several 100 basis points below our full year guidance here in the Q1. We currently expect our margins to be fairly similar to each other in the second and third quarters at around our overall full year average With the Q4 being the strongest quarter of the year, we expect adjusted net interest and other expense in 20.24 to be approximately $70,000,000 representing a 20% increase versus last year. This increase is attributed to less interest income on lower cash balances as we pay off $1,300,000,000 in debt in 2023 2024. We expect our tax rate to be 20% and our average share count to be 123,500,000 similar to what it was in the 4th quarter. Speaker 300:25:23This all results in our initial 2024 adjusted EPS guidance to be in the range of $4.55 to $4.75 with the midpoint being flat to what we generated in 2023. We expect approximately 20% of our full year earnings to come here in the Q1 As our tax rate will be about 200 basis points above our full year average and net interest expense will be down about $5,000,000 sequentially from the Q4 before increasing over the remainder of the year. As we enter 2024, we closely manage those items that are fully within our control such as delivering on our innovation pipelines, reducing our working capital and remaining active with capital deployment, while continuing to take appropriate actions to further streamline and optimize the company following its transformation. When current industry headwinds subside, revenue will be in an even stronger position to capitalize on this recovery, continue to highlight our differentiation and realize the full potential of what we have become. With that, operator, We would now like to open up the call for questions. Operator00:26:38Thank Our first question today comes from the line of Jack Meehan from Nephron Research. Please go ahead. Your line is now open. Speaker 400:27:10Thank you. Good morning. Prahlad, wanted to just start and get your thoughts how you're feeling about Visibility into the business now, the macro is still pretty volatile. Just would be great to hear what you're hearing from customers and the things that Build your confidence this 2024 outlook is in the right spot? Speaker 200:27:32Good morning, Jack. 23 certainly did not play out as we or others had envisioned it. Well, I think it was good to see that in the Q4, while the environment remained challenging, For the first time in 2023, it did not deteriorate more than what we had anticipated. I mean, I would say as we look forward into 2024, including here in the Q1, we are not anticipating any sort of meaningful or significant improvement. But I would say rather more of a continuation of current trends. Speaker 200:28:08So things do start to pick up. I would say that I would expect that to provide more upside to the current outlook. So, somewhat where we are is more of a temporary holding pattern before demands comes But I'm optimistic that we are perhaps what we are experiencing currently is more of a trove. As far as we go, I think One of the things that do help us is the portfolio transformation journey that we have gone through. If you look at our portfolio now, we have more diagnostics than our peers. Speaker 200:28:42We've got less of a capital intensive business now than our peers. We've got a meaningful software business and this differentiation allows us to have the confidence that We are in a pretty decent spot. Speaker 400:29:00Great. And then follow-up for Max, Just as you I appreciate the color on the pacing you provided. If you look at sales, so core down, mid singles in the Q1, Just to get to the ramp you're talking about, just wanted to confirm, are you kind of assuming this is just comp dynamics? Is there anything else like noteworthy you're assuming in terms of the assumptions behind that? Thanks. Speaker 300:29:28Yes. Hey, Jack. So comps is definitely driving the majority of it. So we mentioned a little bit in the prepared remarks, as you pointed out, that we'd be down mid single digits for Q1, a slight improvement in Q2, but still negative with the return to growth in the Q3. I wouldn't say that we are expecting material change in the market environment in the second half. Speaker 300:29:47Is always a little bit of quarterly nose, but it's mostly comp driven. And another way to think about it is, if you look at our 2 year stack Between the first half and second half, both are at a low single digit with those sort of annual cadence that I had previously mentioned. Speaker 400:30:12Thank you. Operator? Operator00:30:15The next question today comes from the line of Matt Sykes from Goldman Sachs. Please go ahead. Your line is now Speaker 500:30:22open. Thanks for taking my questions. Good morning. Maybe Prahlad, one to start for you. As you Look at the Life Sciences segment and the number of acquisitions you've made in that business, how do you feel the synergies are playing out in terms of covering the needs of researchers in both academic and biopharma? Speaker 500:30:37Are there portions of their workflow and spend where you see gaps in your offering? And do you think you might lose the customer touch points along the way Because of those gaps, do you think you're capturing the customers through the majority of their early R and D workflow? And if there are gaps, is that an organic solution, inorganic solution? Speaker 200:31:03I think the whole journey that we have gone through on our portfolio transformation was indeed to fill the gaps that we had in our portfolio. And if you recall 2 years ago, It was primarily a small molecule portfolio in preclinical research and differentiation preclinical research and development. I mean the whole concept of what we went through our acquisition journey was to fill the gaps in around large molecules, biomolecules, cell and gene therapy. And I think the synergies that we have started seeing from the Horizon, Cydian, Biolegend and Nexelome acquisition is on the biomolecule side of the table. So I think we feel very good where we are. Speaker 200:31:50And if you add the software component that allows us More differentiation, we feel very good with the portfolio that we have. Will the other additions that we will continue to make? But I think we feel very good with the portfolio that we have built. Speaker 500:32:11Great. Thanks for that. And then Max, Just on phasing for diagnostics specifically, how are you thinking about as we progress through the year terms of Diagnostics growth and RECOVER, there's some different types of comps that business has relative to maybe Life Sciences. And then specifically on China ImmunoDx, How are you thinking about that phasing of growth within your 2024 guidance framework? Thanks. Speaker 300:32:42Yes. Hey, Matt. So I would say from the diagnostics ramps perspective, the first half will be, I think roughly flat from a diagnostics standpoint. So if you remember, we have the big, the continued headwinds we'll have in Applied Genomics Throughout the year as we still are going through the additional COVID purchases and the life sciences weakness. And so it will be about flattish for the first half and then second half we're anticipating a return to mid single digit growth for the diagnostics business. Speaker 300:33:12In terms of your question on immunodiagnostics China, our assumption there for the full year is mid single digits growth. However, if you exclude the impact of a change in go to market strategy we had for one of our legacy infectious disease businesses in China, the growth there is still similar to what it was in 2023 in terms of the high single to low double digit range. And the reason why we made that change in the legacy business was actually to improve the profitability of us overall, though it will come with a little bit of a hit from a revenue perspective. Speaker 600:33:49Great. Thank you. Operator00:33:53The next question today comes from the line of Josh Waldman from Cleveland Research. Please go ahead. Your line is now open. Speaker 700:34:03Hey, thanks for taking my questions. 2 for you. First, either Speaker 100:34:07for a lot of back. Wondered if Speaker 700:34:08you could provide more context on what you're seeing in the life science Instrument business. I guess the Instrument business broadly both Life Science and Applied Genomics. I mean it looks like Both of those came in a bit better than you were thinking when you guided Q4. I'm curious if maybe you didn't see quite the pullback from pharma you were expecting or maybe Did you see some budget flushing in November December come through? And then, what's assumed for those businesses in 2024? Speaker 300:34:43Yes. Hey, Josh. So I would say if you look at the 4th quarter results, To your point, instrumentation on both the life sciences and applied genomics standpoint fared a bit better than our expectations. I think coming into the quarter, we had mentioned that we were wanting to be a little bit more conservative on our instrumentation assumptions. And so those did prove out To be conservative and they were slightly better, although we wouldn't really call it there was a budget flush activity in the 4th quarter. Speaker 300:35:10So as we look out to 2024, we do still believe our instruments will be pressured, for this year. And I think if you look at the overall assumptions, both the life sciences instruments and applied genomics will be down in the high single digit range for 2024 and that will put them closer in line to what their LRP is when you look over that at that over a 4 or 5 year period. Speaker 700:35:36Got it. Okay. And then Prahlad, can you talk about any momentum you're seeing in key accounts as it relates to Revenues ability to cross sell or realize commercial synergies following the divestiture and rebranding. I guess, are there any specific examples you can point to of how Remedy is making progress towards being a more effective strategic partner, specifically within Pharma? Speaker 200:36:04Yeah, Josh. I think, and I mentioned that during one of the healthcare conferences earlier in January, Our example with one of our most important customers that we talked about in the pharma side is how we are able to leverage our relationship both on the diagnostic and the life sciences side of the portfolio to not only license technology to them, but also provide the tools and capabilities and our service offering from the DX side that allows for being part of the journey of drug development for Our important customers all the way from preclinical research and licensing them the technology, Providing them the tools and capabilities that allows them to use and leverage that technology towards drug development And then being part of the journey with them through their development process as they take it through the regulatory approval processes and then further on Leveraging our global lab infrastructure from the omics side of the business to be able to follow-up those patients both for efficacy of the drug and for follow ups. So that sort of allows us initially when we were on the small molecule side in life science, Since our focus was on providing them with reagents and tools and instruments and pre in vivo imaging components, They just do their research. Speaker 200:37:30Now with the full expansion of our portfolio, it allows us to be with them from the start to when it gets to commercialization. Speaker 700:37:44Makes sense. Thanks, guys. Operator00:37:48The next question today comes from the line of Patrick Donnelly from Citi. Please go ahead. Your line is now open. Speaker 800:37:56Hey, good morning guys. Thanks for taking the questions. Probably one for Max on the margin side. Understand this year more flattish given the revenue outlook, it sounds like you guys are continuing to implement some cost plans there. Can you just talk about the confidence in that 75 bps expansion algorithm that you guys talked about at JPM and just this becoming that 30 plus percent margin business in the relative near term, what are the key levers you see And maybe just the process that went into revisiting that algorithm, did you guys want to set it more as a floor where you saw a clear path to on it, even the China piece sounds like you're chasing more profitability there. Speaker 800:38:32So maybe just kind of pull the curve back a little on the margins and again that algorithm you guys set? Speaker 300:38:40Yes, sure. Hey, Patrick. So as we step back and look at it from a margin perspective, I think that 75 basis points, it was taken down from the previous MRP of 75 to 100 basis points and that was mostly just attributed I think to the change in the top line assumptions. If you look at the assumption of the market on average is growing 4 to 6, we're a couple of 100 basis points better than that. That's going to drive natural operating leverage, just from a pure growth perspective. Speaker 300:39:09And so even in addition to that, I think where we have Confidence in sort of the margin expansion is really still the fact that we're still in the early innings of what the actual overall structure of this company should be given all the transformation, right, In terms of the number of acquisitions and integrating them into our core business and processes, as well as sort of working our way through all the stranded costs related to the divestiture. I think we have a lot of Stokes irons in the fire from an op margin expansion standpoint outside of just the natural volume leverage you would get. I think there is a high degree of confidence and in terms of your question in terms of the amount of conservative or whether it's a floor, I think we thought it was fair number that we can consistently deliver on with that expected growth algorithm. Speaker 800:39:55Okay. That's helpful. Prahlad, maybe just on China, it sounds like you guys talked a little about the immune ODX on an earlier question. But just in terms of this year, What you're seeing there, confidence both from the diagnostics and then the Life Science side, which is obviously a little more variable. Again, it sounds like you guys are making some changes in terms of going after a little more profitable business, but just the outlook in China, confidence in that region and what you're seeing here near term? Speaker 800:40:20Thank you. Speaker 200:40:24Yes, Patrick. I think nothing's Speaker 900:40:27changed in Speaker 200:40:27our view regarding China And that level of confidence is because of the portfolio differentiation. I mean, this is where I think it really comes down to a good understanding of the markets and the segments where we In that market, if you just look at the portfolio that we have built out over there, in terms of Life Sciences side, I think on the instrumentation side, we will continue to see some pressure, which is not very different from the other global markets. I think on the reagents side, we will continue to see it coming back. On the immunodiagnostics side, I think excluding the impact of what Max talked about for a small legacy business that helps us improve profitability, it is going to be on a growth trajectory. Newborn screening is going to get impacted, but we've got quite A few of our reagents that are awaiting an MPA approval and hopefully they will compensate for the pressure that we will see from the birth rate decline. Speaker 200:41:29So overall, I think it again comes back to the differentiation of our portfolio in China and outside of China. The lower it sort of risk mitigates our portfolio, both the exposure to the diagnostics, Life Sciences and the software market, which sort of in the longer run is going to be the competitive advantage that we will have. Operator00:42:00The next question today comes from the line of Andrew Cooper from Raymond James. Please go ahead. Your line is now open. Speaker 1000:42:09Hey, everyone. Thanks for the questions. Maybe first, I want to talk about margins a little bit more just for this year. You have modest top line organic growth. You've got 100 bps coming from price, some cost action. Speaker 1000:42:20So I guess, What are some of the counterpoints to prevent seeing maybe a little bit of expansion year over year in 2023? Or maybe asking it a different way, what's the threshold of revenue growth you need to see to actually see that margin expansion? Speaker 300:42:40Yes. Hey, Andrew. I think as we previously mentioned, the one dynamic you didn't mention for 2024 that we have already previously discussed is the fact that we will have variable costs that are returning in 2024 and I do not believe we are alone. And that dynamic as you've heard some of the others in the industry mention it. So I think from that perspective, that's really what's offsetting to your point the price and the structural cost actions that we have been taking. Speaker 300:43:03As you look out more cost actions that we have been taking. As you look out more longer term, I would say in a normal environment where you don't have that snap back of the variable cost, Even with, I would say, a lower growth than the LRP model assumes, I would anticipate us still being able to drive Margin expansion given some of my earlier points, but again, volume is a heavy driver when you think about it from a margin expansion standpoint. Speaker 1000:43:32Okay, helpful. And then maybe just one on the e commerce rollout. Any early feedback there or metrics you can share in terms of what the rollout has really looked like and whether it's more on the cost side, how we think about customer retention, sort of what the benefits are as we think about that moving beyond just the U. S. Rollout and globally longer term? Speaker 200:43:57Yes, Andrew. I mean, as we mentioned, we just rolled it out in mid December. So it's early days of the MVP and we are seeing good traction on it, from a customer flow perspective, the OUS launch is expected to be out in the early part of the second quarter. So while I would say it's 4 to 5 months ahead of schedule, it is still early days, looks promising. I think over the longer term, the benefit that we get out of it is not just synergies of being able to offer our comprehensive portfolio to our customers on a common platform, but obviously the synergistic opportunities that you get from a cost perspective or an OpEx perspective. Speaker 200:44:43So we are very excited about what we are hearing and seeing, but early days is the best way I would frame it for now. Speaker 1000:44:53Great. Appreciate it. I'll stop there. Thanks. Operator00:44:59The next question today comes from the line of Catherine Schulte from Baird. Please go ahead. Your line is now open. Speaker 1100:45:07Hey guys, thanks for the questions. Maybe first, your software and genomics lab businesses have faced headwinds over the last year due to some contract renewal and renewal and project timing dynamics. You mentioned those normalizing in 2024, but can you just walk us through the timing there and what kind of performance you expect from those businesses both for the Q1 and the full year? Speaker 300:45:33Yes, sure. Hey, Catherine. So as we look at maybe if we take a step back and just think about our guidance more holistically, I think the way to think about it is, we're assuming sort of a market down low single digits here in 2024. Reveny grows couple of 100 basis points above the market, so call that flat overall. And then the way we get to 2% is sort of that normalization of The software and omics business. Speaker 300:45:58So it's about a 200 basis points specific revenue tailwind for this year. In terms of the individual assumptions for those businesses, For the software business, it declined high single digits in 2023. We expect it to return to high single digits growth in 2024. And for the Omics business, that was down a little bit more than 30% in 2023 and we are expecting that to be flat in 2024, so essentially assuming none of those new contracts get signed, we continue to remain encouraged by the pipeline we have for that business. If we're able to close on some of those deals, that would be upside to what's assumed in the guidance case here. Speaker 1100:46:37Okay, great. And then how should we think about free cash flow in 2024, just particularly with those AES outflows coming back to you? Speaker 300:46:49Yes. So from a cash flow perspective, again, we are encouraged by the results that we had here in the Q4. For the overall year, that would have meant about roughly more than $400,000,000 once you normalize for those AES outflows. As we look to 2024, Our anticipation of free cash flow generation is about $450,000,000 The AES outflows will actually come back to us as inflows in investing Cash flow, if you add that to the $450,000,000 we are targeting to have about $600,000,000 of overall cash generation in 2024. Operator00:47:30Thank you. The next question today comes from the line of Vijay Kumar from Evercore ISI. Please go ahead. Your line is now open. Speaker 1200:47:40Hi guys. Thanks for taking my question. Good morning to you Prahlad. Maybe my first one for you on This Q1 organic guidance assumption of down mid singles, you did call it comps. You look at Q4 down low singles. Speaker 1200:47:56Most of your peers are assuming first have to be similar to Q4 jump offs. So maybe just talk sequentially Why perhaps what's driving that change from down low singles to down mid singles? Speaker 200:48:13Yes, I think as we talked about, we are from a Q4 to a Q1 perspective, a lot of it is obviously the comps that we had from last year. So it is more an impact of that than anything else. And I think as Max laid out the cadence of the calendar for the year, There is nothing outside of that, that I would say. We do have some pressure from reproductive health, especially in China. And on the instrument side, we will see some impact of that. Speaker 200:48:43But more than anything else, it is just timing is where I would allocated to the impact that we see on 1Q versus anything else. Yes. Speaker 300:48:53I mean, the only point I'd add to that, Vijay, you mentioned it yourself, right? Most are saying that the first half will be similar to what they had in Q4 and that's what I just mentioned previously, right, that our first half assumption is down low single digits, which is in line with what we just printed for the Q4. Speaker 1200:49:10Understood. And Max, maybe One for you, if your gross margins in Q4 down sequentially, so what happened in Q4? And When you think about fiscal 2024 guide, is the guide assuming gross margins to be flattish up or down versus fiscal 'twenty three. Speaker 300:49:31Yes, sorry, Vijay, I might have missed the first part of your question. I think you were mentioned on Just asking the question on gross margin for this year. So in the Q4, the gross margin was about 60%. It was down quarter over quarter as we had some mix dynamics play out in the Q4. As we look to full year 2024, we expect gross margin to be roughly flat year over year And we expect it to build as the year goes on as we get increased volume leverage throughout the year. Speaker 1200:50:01And so it's essentially the mix improves, Max, is that the assumption like what's driving the step up from Q4? Speaker 300:50:10Yes, I think from Q4 to Q1, it's relatively similar. We're expecting kind of a similar mix dynamic from Q4 to Q1. As the rest of the year It is mostly a volume leverage story as opposed to a massive change in mix dynamics. Speaker 1200:50:25Fantastic. Thanks guys. Operator00:50:31The next question today comes from the line of Dan Brennan from TD Cowen. Please go ahead. Your line is now open. Speaker 600:50:40Great. Thanks for the questions, guys. So ImmunoDx, another solid quarter in year. Speaker 200:50:46Can you just give us a Speaker 600:50:46sense of kind of What's driving the strong growth and like what's the range of outcomes we can expect for 2024? Speaker 200:50:56And then I think again, as I've talked about earlier, it is the differentiated portfolio of the high end euro immune tests that we have in China That allows us to be in the face of limited competition that we see in that marketplace and that has innovation pipeline has worked for us and then we expect that to continue as we look forward. Speaker 600:51:26Got it. Okay. Maybe on pharma, I know you kind of talked about it throughout a little bit, but it key drag at Q3. You guys talked about instruments still under pressure here, maybe from a post COVID high. Just can you speak to some of your discussions with pharma? Speaker 600:51:41What do we expect this year? Just kind of any more color on kind of what you're hearing there? Thank you. Speaker 200:51:49Yes, Dan. I think on the instrument side or on the capital side, I think we will continue to see some pressure or at least the current trend we expected to continue in the first half of the year. The benefit again that allows us is that the reagent side of the portfolio, once that starts stabilizing and coming up in the second half of the year, That's what the assumption that we have in our current forecast allows us the confidence that we would look. Overall, as we see pharma, I continue to believe that this is a temporary growth in the marketplace and I think it will continue it will come back to what we have seen is normal pattern of mid single digit growth in the market over the past several years. Speaker 300:52:43Got it. Thank you. Operator00:52:47The next question today comes from the line of Yves Bernstein from Bernstein Research. Please go ahead. Your line is now open. Speaker 900:52:57Good morning. Thanks a lot for the questions. First one, you said that you've already taken structural cost measures so far this year and you'll be taking additional cost actions in cost actions in 2024. Can you just give us some more color on what those actions are and what's giving you confidence and maybe the ability to achieve those benefits in this Speaker 300:53:23So from a structural cost action perspective, the easiest way to think about it is really just rightsizing the company given all of the transformation, Whether that's the integration of the acquisitions, which I mentioned, we're still what we would consider in the early to mid innings from a process standpoint. And then it's working our way through the stranded costs from the divestiture. So that's really what's driving the structural cost actions. In terms of the confidence, those actions have already been taken place and communicated. There's a little bit of timing in terms of When the actual cost comes out throughout the course of the year, but those actions have more or less already been executed and it's just a matter of timing at this So we have, I would say, a high degree of confidence in those for this year. Speaker 900:54:11Great. Thank you. And then you just talked about integration of your acquisitions. You said Still early to mid innings. But you also shared an example of how you brought Biolegend together with other parts of your business to do something really cool. Speaker 900:54:34Where are you really against your synergy target of $100,000,000 in year 5, you're 2 5ths of the year 2 5ths of the way through. Where would you put yourself on that scale? Speaker 200:54:49Yes, I'm not good morning, I don't think I'm going to quantify as to what The dollar amount of how much synergies we are seeing, the intent of what we provided as an example is How we are starting to see not just commercial synergies from the full portfolio, but operational and technological synergies. I think as Max said, I would say we are still in the early to mid innings Of the opportunities that we see from integration of the acquisitions, keep in mind, 2 of our acquisitions, Biolegend and EUROIMMUN are 2 of our strongest and fastest growing businesses. And I think the opportunities that they provide are crown jewels in our portfolio and we expect them to continue to perform well. Our intent is how do we support those businesses And how do we leverage the opportunities that we see across the portfolio with them? Speaker 900:55:51Great. Thank you. Operator00:55:55Our final question today comes from the line of Luke Sergos from Barclays. Speaker 1300:56:05So real quick on the 1Q Margin target, you said like a few 100 basis points lower than your full year. So I assume that's around like 25%. Can you talk about Even though it's the growth and everything looks a little bit like 4Q, can you just talk about what's really driving that decel and then kind of where you're going to get the margin uplift throughout the year on that steep ramp? Speaker 300:56:36Yes. Hey, Luke. So I think maybe just let's tackle the margin question first to kind of lead with that. So look, I don't think your math is that far off from Q1. I think we've given you the pieces below the line in Q1 that you're going to get to roughly that number. Speaker 300:56:51As you look at comparing that to Q4, I would say the 2 main really the main driver of that is just a volume stepped down from a top line perspective. If you look at the actual overall gross margin percentage, it's roughly flat quarter over quarter. OpEx costs are similarly in line quarter over quarter. And so from that standpoint, I don't think really much has changed. Again, as you then look at the volume ramp over the remainder of the year, as we mentioned, 1, you're going to have the timing of the structural cost actions coming into play. Speaker 300:57:23And the second piece is you're going to have volume leverage as the year builds. So that's how I would think about it from a margin perspective. In terms of the slowdown from an organic growth perspective between Q4 to Q1, I think we've mentioned part of that is definitely comp driven and the biggest piece of that is going to be on the immunodiagnostics business outside of China. Outside of China in the first half last year, immunodiagnostics grew in the high teens. We've always said it should be sort of a low double digit. Speaker 300:57:52And so there is just some normalization there on a 2 year stack for immunodiagnostics business outside of China. Speaker 1300:57:59Yes, great. Thanks. I was just referring to the 4Q to 1Q kind of just the similar you have a pretty steep decline there in the margin. I got The core commentary. And then I guess on the software piece, you guys have talked about converting a lot of these customers more to SaaS space and that's kind of aiming to reduce the lumpiness in the orders and talk about the progress that you're seeing there. Speaker 1300:58:25And On the non SaaS piece, can you talk about what the orders look like and if they're inflecting because as you talked gave that 2% framework prior, you were talking about just if software is not a headwind next year or the way that the contracts come in, that will just be at least 100 basis points of lift? Speaker 300:58:47Yes. So, Menel, maybe start with your second question first, Luke, so as I mentioned, software business was down high single digits in 2023. It should be moving to up high single digits. That's what's assumed in our guidance here for 24. That is roughly 125 basis points to the overall company from an organic growth perspective. Speaker 300:59:09And so as you look at that dynamic, it's really driven by this contract renewals. Again, that's a business that has upper 90s percent renewal rate. And so most of the contracts we know are coming due and I would say have a high degree of confidence in our ability to deliver on our 2024 expectations. And then to your first question on sort of the SaaS transition, I think we continue to make really good progress. We view the transition to SaaS as actually a differentiator For us versus our peers, we believe we are ahead of them in terms of that transition. Speaker 300:59:41And so although that might create a little bit of noise from a revenue recognition standpoint, It is the right thing to do for the business and we think our SaaS products are going to help us actually take share from our competition. Yes. And Luke, in the longer Speaker 200:59:52term, it Tom, it definitely help us increase revenue and reduce our volatility for that business, which I think is another one of the opportunities that the Software business provides us from a differentiation perspective. Speaker 1301:00:09Great. Thank you. Operator01:00:13This concludes today's question and answer session. I'd like to pass the call back over to Steve Willoughby for any closing remarks. Speaker 101:00:22Thank you. Thanks for your interest and questions today, and we look forward to further discussions over the coming weeks. Have a good day. Bye bye.Read moreRemove AdsPowered by Conference Call Audio Live Call not available Earnings Conference CallRevvity Q4 202300:00 / 00:00Speed:1x1.25x1.5x2xRemove Ads Earnings DocumentsSlide DeckPress Release(8-K)Annual report(10-K) Atlantica Sustainable Infrastructure Earnings HeadlinesGREENING AND ATLANTICA PARTNER TO DEVELOP RENEWABLE PROJECTS IN THE USApril 11, 2025 | morningstar.comAtlantica Closes the Acquisition of a Transmission Line in UruguayApril 10, 2025 | markets.businessinsider.comTrump to unlock 15-figure fortune for America (May 3rd) ?We were shown this map by former Presidential Advisor, Jim Rickards, one of the most politically connected men in America. Rickards has spent his fifty-year career in the innermost circles of the U.S. government and banking. And he believes Trump could soon release this frozen asset to the public. 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Email Address About Atlantica Sustainable InfrastructureAtlantica Sustainable Infrastructure (NASDAQ:AY) owns, manages, and invests in renewable energy, storage, natural gas and heat, electric transmission lines, and water assets in North America, South America, Europe, the Middle East, and Africa. The company was formerly known as Atlantica Yield plc and changed its name to Atlantica Sustainable Infrastructure plc in May 2020. 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There are 14 speakers on the call. Operator00:00:00Hello, and welcome to today's MeVity, Inc. Q4 2023 Earnings Conference Call. My name is Bailey, and I will be the moderator for today's call. I'd now like to pass the conference over to our host today, Steve Willoughby, Senior Vice President of Investor Relations. Please go ahead. Speaker 100:00:28Thank you, operator. Good morning, everyone, and welcome to Remedy's Q4 2023 Earnings conference call. On the call with me today are Prahlad Singh, our President and Chief Executive Officer and Max Grecowiak, our Senior Vice President and Chief Financial Officer. Before we begin, I'd like to remind everyone of the Safe Harbor statement we have outlined in our press release issued earlier this morning and also those in our SEC filings. Statements or comments made on this call may be forward looking statements, which may include, but are not necessarily limited to, financial projections or other statements of the company's plans, objectives, expectations or intentions. Speaker 100:01:07These matters involve certain risks and uncertainties. The company's actual results may differ significantly from those projected or suggested due to a variety of factors, which are discussed in detail in our SEC filings. Any forward looking statements made today represent our views as of today. We disclaim any obligation to update these forward looking statements in the future, even if our estimates change. So you should not rely on any of today's statements as representing views as of any date after today. Speaker 100:01:36During this call, we will be referring to certain non GAAP financial measures. A reconciliation of the non GAAP financial measures we plan to use during this call to the most directly comparable GAAP measures is available as an attachment to our earnings press release. I'll now turn it over to our President and Chief Executive Officer, Prahlad Singh. Prahlad? Speaker 200:01:56Thank you, Steve, and good morning, everyone. As we highlighted in our pre announcement a few weeks ago, while industry headwinds continued throughout the end of the year, We were able to perform slightly better than we had anticipated and finished the 4th quarter with a 3% decline in non COVID organic revenue. While Max will provide more details on the quarter in a bit, I would say that our Stronger than anticipated results were broad based as both our Life Sciences and Diagnostics segments performed better than expected. I would also highlight that our performance was well balanced geographically as each major region performed in line to slightly above what we had assumed. We also did a good job continuing to tightly control our expenses in light of the challenging environment that persisted through year end. Speaker 200:02:57And along with some favorable one time tax benefits helped deliver additional EPS upside in the 4th quarter. We also had a very strong cash flow in the quarter with nearly $200,000,000 of free cash flow while continuing to execute on our capital deployment initiatives. For the full year 2023, we generated 2% non COVID organic growth. While not what we hoped for at the start of the year, I think you will see that our performance was differentiated versus the broader industry and likely will be near the high end of the peer set for the year once the dust fully settles. We expect this differentiated financial performance to continue going forward. Speaker 200:03:52As demonstrated in the new financial framework, We recently provided for our expected performance over the coming years. As part of this new long range outlook, We now expect Reviti's organic revenue growth to be 200 basis points above the broader industry regardless of the macro environment. In a normal year, we would expect this to result in 6% to 8% organic growth and seventy basis points of operating margin expansion annually. In the post COVID world we all now operate in, We anticipate this level of growth will result in performance that continues to be at the high end of our industry overall. As we highlighted during a recent investor conference, we expect approximately 60% of our business that is comprised of immunodiagnostics, life sciences reagents and our signal software business to grow in the 9% to 11% range over the coming years, generating mid single digit growth on their own for the total company. Speaker 200:05:05Given the stronger profitability of these segments, as they continue to grow faster than the remainder of the business, We expect it to result in natural margin expansion as they become an increasingly larger piece of the overall company over time. Reviti is extremely well positioned to capitalize on some of the most exciting areas of pharmaceutical research and development such as cell and gene therapy, multiomics and precision medicine. We are also involved in some of the most durable higher growth areas within clinical diagnostics such as autoimmunity, tuberculosis and other emerging infectious diseases. With what our company has become over the last several years and where we are planning on going in the future, I think you will see that Reviti will continue to stand out as a very unique company. We have a differentiated approach with our customers, our competitive and novel product portfolio with continuous innovation and a unique position within the attractive life sciences and diagnostic categories in which we compete. Speaker 200:06:26A good example of this in the Q4 was the launch of our Ionis Q system in our newborn screening business. The Ionis Q system is a first of its kind workflow which streamlines molecular testing for both spinal muscular atrophy and SKIT in newborns. It is a new and complete CEIVD solution This consists of a new PEAP CR equipment with dedicated software and a specialized diagnostics kit. With no watch steps being needed in the new workflow, it results in a significantly faster turnaround time and less hands on involvement from sample to answer than existing methods. This allows for lower operating costs greater sustainability as fewer consumables and plasticware are required. Speaker 200:07:22The introduction of this Innovative solution is also perfectly timed from a commercial perspective. As the European Alliance for Newborn Screening and Spinal muscular atrophy mandates that by 2025, all newborns in Europe should be screened for SMA going forward. Our new Ionis Q system is just one example of how we are continuing to bring Cutting edge and innovative solutions to market from across the company benefiting both our customers and ultimately the patients they serve. We have also been making good progress on our operational initiatives. A good example of this is the launch of our new e commerce platform which went live in the U. Speaker 200:08:14S. In mid December approximately 5 to 6 months earlier than we anticipated. The platform's integrated design was built Specifically for the needs of what our business has become. It is expected to be extremely consumer friendly while also over time delivering both revenue and operating synergies. We expect this new system to go live outside the U. Speaker 200:08:42S. In early 2Q. Another thing I'm extremely proud See is the strong collaboration that is occurring amongst our teams across the company. A great example of this was how last year we had a sole source antibody supplier for one of our diagnostics assays begin to have quality inconsistencies in their batches. Through the rapid collaboration amongst scientists from Euroimmune, Biolegend and Horizon, Within 9 weeks, we had developed our own replacement antibody, validated it and were able to manufacture it in sufficient scale for commercial use. Speaker 200:09:28The ability and agility would never have been possible in the company of the past And I'm not sure it would be possible at most companies today other than Reviti. As we look ahead to this year, we expect the ongoing headwinds from our pharma and biotech customers to continue, particularly in the first half of the year as they still are working through the impact from their elevated spending levels during the COVID years. We are assuming this pressure will begin to stabilize in the back half of the year when we anticipating returning to growth for the company overall. In light of the dynamic end market challenges continuing into 2020 4, as well as the return of some of the variable costs that we reduced in 2023, We have recently implemented additional structural cost actions to protect our strong profitability through this temporary period. We anticipate these actions will allow for our operating margins to remain approximately flat year over year at 28% this year. Speaker 200:10:42Despite the low single digit organic growth, we expect to repeat into 2024. We expect This to result in our 2024 adjusted EPS to be in the range of $4.55 to $4.75 With our significant number of acquisitions over the past several years, Coupled with the large divestiture we completed in early 2023, we still have many areas to further in order to reach our full potential as a company. The significant actions we took in 2023 Combined with the additional measures being implemented as we begin 2024 have put us on a good trajectory to further streamline and adjust our operations for the business we have now become. It also strongly positions us to capitalize on the leverage potential that exists in our company once industry growth normalizes. Overall, when looking back on 2023, I'd say it certainly ended up playing out quite differently than we had anticipated when sitting here a year ago. Speaker 200:12:01However, I'm so proud of the transformation that we have undergone over the past few years, which we ultimately completed last year. While we are continuing to face external challenges, I'm extremely grateful for what Reviti has become and the significant efforts of so many who have made it come to fruition. Without everyone's efforts and the rebirth of the company, our differentiated performance in 2023 would not have been possible. We remain confident that we will emerge from this temporary period of industry headwinds as a unique and stronger company that remains well positioned to help expand the boundaries of human potential through science. With that, I'll now turn the call over to Max. Speaker 300:13:00Thanks, Prahlad, and good morning, everyone. The company demonstrated its perseverance in the Q4 during a period in which underlying industry demand continued to remain dynamic. I am proud of our team's performance despite these challenges continuing through year end, allowing our results to exceed our expectations for the quarter. As I'll comment on more in a bit, we are now assuming the current market environment remains largely in place through at least the first half of this year, which will continue to put pressure on our results and cause our full year expectations to look fairly similar to what we achieved in 2023. However, we would expect our performance to be somewhat of the inverse of what we saw last year with the first half of twenty twenty four remaining challenged and facing organic revenue declines before returning to growth in the second half. Speaker 300:13:55While we work through this dynamic period, We have continued to remain extremely focused on those items and actions that are more fully within our control. We progressively tightened our expense management efforts throughout last year. And as previously mentioned, we have already implemented significant additional structural cost measures So far this year, which we anticipate will allow our operating margins to remain flat at 28% this year, despite our low single digit growth outlook paving the way for greater operating leverage in the future when growth normalizes. We also made good progress with our balance sheet and cash flow in 2023. In the Q4, we generated $196,000,000 of free cash flow as we made meaningful progress on collections and inventory management. Speaker 300:14:43Excluding the divestiture related outflows we incurred during the year, much of which will be coming back to us in 2024, we generated over $400,000,000 of free cash flow in 2023 overall. Given the amount of change that has occurred at the company over the past year, I view this as very strong performance and we are well to continue executing on our capital deployment initiatives this year. Now moving to our specific Q4 and full year results. Overall, the company generated total adjusted revenues of $696,000,000 in the quarter, resulting in a 3% decline in non COVID organic revenue, which was above the high end of our guidance. The outperformance was fairly broad based as both our Life Sciences and our Diagnostics segments performed slightly above our expectations for the quarter. Speaker 300:15:35FX was a 1% tailwind and we again had no incremental contribution from acquisitions. For the full year, we generated $2,750,000,000 of total adjusted revenue, which was comprised of 2% non COVID organic growth, No impact from FX or M and A and a modest $3,000,000 contribution early in the year from COVID. As it relates to our P and L, we generated 27.5 percent adjusted operating margins in the quarter, which were in line with our expectations. For the full year, our op margins were 28%, which represented approximately 100 basis points of expansion excluding the removal of related revenues. We incurred a favorable pricing impact of approximately 130 basis points in the quarter, which brought the full year impact from pricing to approximately 150 basis points. Speaker 300:16:30We continue to expect at least 100 basis points of favorable pricing annually going forward. Looking below the line, we had adjusted net interest and other expense of $16,000,000 which was largely in line with our expectations. For the full year, our adjusted net interest and other expense was 58,000,000 Our adjusted tax rate was 12% in the quarter, which was favorable by a few 100 basis points to our expectations due to a couple of onetime tax items. These favorable discrete tax items contributed approximately $0.05 to our EPS in the quarter. For the full year, our adjusted tax rate was 18.6%, but would have been approximately 20% and in line with our expectations, Excluding the favorability we incurred here in the 4th quarter, which we do not expect to repeat in the future. Speaker 300:17:22We averaged 123,400,000 shares outstanding in the quarter and 124,800,000 for the full year. This all led to adjusted EPS in the Q4 of $1.25 which was $0.09 above the midpoint and $0.07 above the high end of our expectations. Our full year 2023 adjusted EPS was $4.65 Moving beyond the P and L, As I mentioned, we generated free cash flow of $196,000,000 in the quarter, while on a full year basis, our free cash flow was $198,000,000 which includes a headwind of slightly over $200,000,000 from one time divestiture and rebranding related activities. Also, as I previously mentioned, we expect a large portion of these outflows to reverse in 2024 and positively impact our investing cash flows when they come back to us. As for capital deployment, we continue to remain active in the 4th quarter. Speaker 300:18:22We purchased an additional $400,000,000 of U. S. Treasuries with maturities aligned to the remainder of the $800,000,000 bond we have coming due in September. We now have over $700,000,000 of treasuries on our balance sheet, which will mature shortly before our bond comes due this September that we will use to extinguish this debt. We finished the quarter with a net debt to adjusted EBITDA leverage ratio of 2.8 times. Speaker 300:18:48I will now provide some commentary on our 4th quarter and full year business trends, which is also included in the quarterly slide presentation on our Investor Relations website. The 3% decline in non COVID organic revenue in the quarter was comprised of a 9% decline in our Life Sciences segment and 3% growth in Diagnostics. Geographically, we declined in high single digits in the Americas declined in the low single digits in Europe and grew low single digits in Asia with China flat overall. For the full year, we achieved 2% non COVID organic growth with 5% growth in diagnostics and flat performance in life sciences. The Americas declined low single digits, Europe grew mid single digits and both Asia and China grew mid single digits for the full year. Speaker 300:19:43Within China in the quarter, we experienced mid single digit growth in diagnostics with high single digit growth in immunodiagnostics, offset by a high single digit decline in life sciences. For the full year, China grew in the mid single digits organically with high single digit growth in diagnostics overall, low double digit growth in immunodiagnostics and mid single digit growth in life sciences. From a segment perspective, our Life Science business generated total adjusted revenue of $320,000,000 in the quarter. This was down 8% on a reported basis and 9% on an organic basis. For the full year, our Life Sciences business was flat organically. Speaker 300:20:27From a customer perspective, sales into pharma biotech customers declined in the mid teens in the quarter and in the mid single digits for the year, which was offset by high single digit growth from academic and government customers in the quarter and mid teens growth for the year. Our life sciences instrument revenue represented about 30% of total life science revenue in 2023 and was down high teens in the quarter and down in the mid single digits for the year. Our reagent licensing and specialty pharma services revenue represented 57% of Life Sciences revenue in 2023 and grew low single digits in the quarter and in the mid single digits for the year. Finally, our signal software business, which represented the remaining 13% of life science revenue in 2023, declined double digits in the quarter and in the high single digits for the year. The decline in both the quarter and the full year was in line with expectations and was driven by fewer multiyear contracts renewing, which we anticipate to normalize in 2024. Speaker 300:21:34In our Diagnostics segment, we generated $376,000,000 of total adjusted revenue in the quarter, which was down 4% on a reported basis and 6% on an organic basis. On a non COVID basis, the segment grew 3% versus a year ago in the quarter and 5% for the year. Our immunodiagnostics business represented about 50% of our total diagnostics revenue in 2023 and grew in the mid teens organically excluding COVID during both the quarter and the full year. Our immunodiagnostics business was strong globally as it continued to grow in the high teens outside of China, both in the quarter and the full year. Our reproductive health business, which represented about 34% of total diagnostics revenue in 2023, decline in the low single digits organically in the quarter and the full year. Speaker 300:22:27This business was again pressured by a significant mid 20% decline in our revenue omics lab business in the quarter and nearly 35% decline for the full year. As we transition to 2024, we will have now lapped the contract completions which pressured growth last year and do not anticipate such major year over year declines to continue. These pressures were partially offset by strong performance in 23 from our newborn franchise, which grew in the high single digits overall for the year. Finally, our Applied Genomics business, which represented the remaining roughly 16% of total diagnostics revenue in 2023, continued to see pressure from the slowdown in pharma biotech spending and the hangover effect from elevated clinical lab COVID spending. Non COVID organic revenue for our Applied Genomics business was down in the mid teens during the quarter and was down in the high single digits for the full year. Speaker 300:23:25Now as it pertains to our outlook for 2024, We expect current industry headwinds to remain over at least the next couple of quarters before we begin to face easier comparisons as the year progresses. Our initial guidance for organic growth is similar to what we experienced in 2023 in the 1% to 3% range. From a quarterly pacing perspective, we expect revenue in the Q1 to be down mid single digits with sequential improvement in the second quarter, resulting in the first half still being down year over year overall. We expect to return to positive growth starting in the Q3 this year. We also expect FX to contribute approximately 1% to total revenue based on the rates at the end of December. Speaker 300:24:11Moving down the P and L, we expect to hold our operating margins flat at 28% as our recent structural cost actions will help offset both some variable cost returning and the lower than normal organic growth we expect for this year. We expect total revenue in the Q1 to be the lowest of the year, which when combined with the only partial quarter impact from our recent cost actions, We expect it will result in our operating margins being several 100 basis points below our full year guidance here in the Q1. We currently expect our margins to be fairly similar to each other in the second and third quarters at around our overall full year average With the Q4 being the strongest quarter of the year, we expect adjusted net interest and other expense in 20.24 to be approximately $70,000,000 representing a 20% increase versus last year. This increase is attributed to less interest income on lower cash balances as we pay off $1,300,000,000 in debt in 2023 2024. We expect our tax rate to be 20% and our average share count to be 123,500,000 similar to what it was in the 4th quarter. Speaker 300:25:23This all results in our initial 2024 adjusted EPS guidance to be in the range of $4.55 to $4.75 with the midpoint being flat to what we generated in 2023. We expect approximately 20% of our full year earnings to come here in the Q1 As our tax rate will be about 200 basis points above our full year average and net interest expense will be down about $5,000,000 sequentially from the Q4 before increasing over the remainder of the year. As we enter 2024, we closely manage those items that are fully within our control such as delivering on our innovation pipelines, reducing our working capital and remaining active with capital deployment, while continuing to take appropriate actions to further streamline and optimize the company following its transformation. When current industry headwinds subside, revenue will be in an even stronger position to capitalize on this recovery, continue to highlight our differentiation and realize the full potential of what we have become. With that, operator, We would now like to open up the call for questions. Operator00:26:38Thank Our first question today comes from the line of Jack Meehan from Nephron Research. Please go ahead. Your line is now open. Speaker 400:27:10Thank you. Good morning. Prahlad, wanted to just start and get your thoughts how you're feeling about Visibility into the business now, the macro is still pretty volatile. Just would be great to hear what you're hearing from customers and the things that Build your confidence this 2024 outlook is in the right spot? Speaker 200:27:32Good morning, Jack. 23 certainly did not play out as we or others had envisioned it. Well, I think it was good to see that in the Q4, while the environment remained challenging, For the first time in 2023, it did not deteriorate more than what we had anticipated. I mean, I would say as we look forward into 2024, including here in the Q1, we are not anticipating any sort of meaningful or significant improvement. But I would say rather more of a continuation of current trends. Speaker 200:28:08So things do start to pick up. I would say that I would expect that to provide more upside to the current outlook. So, somewhat where we are is more of a temporary holding pattern before demands comes But I'm optimistic that we are perhaps what we are experiencing currently is more of a trove. As far as we go, I think One of the things that do help us is the portfolio transformation journey that we have gone through. If you look at our portfolio now, we have more diagnostics than our peers. Speaker 200:28:42We've got less of a capital intensive business now than our peers. We've got a meaningful software business and this differentiation allows us to have the confidence that We are in a pretty decent spot. Speaker 400:29:00Great. And then follow-up for Max, Just as you I appreciate the color on the pacing you provided. If you look at sales, so core down, mid singles in the Q1, Just to get to the ramp you're talking about, just wanted to confirm, are you kind of assuming this is just comp dynamics? Is there anything else like noteworthy you're assuming in terms of the assumptions behind that? Thanks. Speaker 300:29:28Yes. Hey, Jack. So comps is definitely driving the majority of it. So we mentioned a little bit in the prepared remarks, as you pointed out, that we'd be down mid single digits for Q1, a slight improvement in Q2, but still negative with the return to growth in the Q3. I wouldn't say that we are expecting material change in the market environment in the second half. Speaker 300:29:47Is always a little bit of quarterly nose, but it's mostly comp driven. And another way to think about it is, if you look at our 2 year stack Between the first half and second half, both are at a low single digit with those sort of annual cadence that I had previously mentioned. Speaker 400:30:12Thank you. Operator? Operator00:30:15The next question today comes from the line of Matt Sykes from Goldman Sachs. Please go ahead. Your line is now Speaker 500:30:22open. Thanks for taking my questions. Good morning. Maybe Prahlad, one to start for you. As you Look at the Life Sciences segment and the number of acquisitions you've made in that business, how do you feel the synergies are playing out in terms of covering the needs of researchers in both academic and biopharma? Speaker 500:30:37Are there portions of their workflow and spend where you see gaps in your offering? And do you think you might lose the customer touch points along the way Because of those gaps, do you think you're capturing the customers through the majority of their early R and D workflow? And if there are gaps, is that an organic solution, inorganic solution? Speaker 200:31:03I think the whole journey that we have gone through on our portfolio transformation was indeed to fill the gaps that we had in our portfolio. And if you recall 2 years ago, It was primarily a small molecule portfolio in preclinical research and differentiation preclinical research and development. I mean the whole concept of what we went through our acquisition journey was to fill the gaps in around large molecules, biomolecules, cell and gene therapy. And I think the synergies that we have started seeing from the Horizon, Cydian, Biolegend and Nexelome acquisition is on the biomolecule side of the table. So I think we feel very good where we are. Speaker 200:31:50And if you add the software component that allows us More differentiation, we feel very good with the portfolio that we have. Will the other additions that we will continue to make? But I think we feel very good with the portfolio that we have built. Speaker 500:32:11Great. Thanks for that. And then Max, Just on phasing for diagnostics specifically, how are you thinking about as we progress through the year terms of Diagnostics growth and RECOVER, there's some different types of comps that business has relative to maybe Life Sciences. And then specifically on China ImmunoDx, How are you thinking about that phasing of growth within your 2024 guidance framework? Thanks. Speaker 300:32:42Yes. Hey, Matt. So I would say from the diagnostics ramps perspective, the first half will be, I think roughly flat from a diagnostics standpoint. So if you remember, we have the big, the continued headwinds we'll have in Applied Genomics Throughout the year as we still are going through the additional COVID purchases and the life sciences weakness. And so it will be about flattish for the first half and then second half we're anticipating a return to mid single digit growth for the diagnostics business. Speaker 300:33:12In terms of your question on immunodiagnostics China, our assumption there for the full year is mid single digits growth. However, if you exclude the impact of a change in go to market strategy we had for one of our legacy infectious disease businesses in China, the growth there is still similar to what it was in 2023 in terms of the high single to low double digit range. And the reason why we made that change in the legacy business was actually to improve the profitability of us overall, though it will come with a little bit of a hit from a revenue perspective. Speaker 600:33:49Great. Thank you. Operator00:33:53The next question today comes from the line of Josh Waldman from Cleveland Research. Please go ahead. Your line is now open. Speaker 700:34:03Hey, thanks for taking my questions. 2 for you. First, either Speaker 100:34:07for a lot of back. Wondered if Speaker 700:34:08you could provide more context on what you're seeing in the life science Instrument business. I guess the Instrument business broadly both Life Science and Applied Genomics. I mean it looks like Both of those came in a bit better than you were thinking when you guided Q4. I'm curious if maybe you didn't see quite the pullback from pharma you were expecting or maybe Did you see some budget flushing in November December come through? And then, what's assumed for those businesses in 2024? Speaker 300:34:43Yes. Hey, Josh. So I would say if you look at the 4th quarter results, To your point, instrumentation on both the life sciences and applied genomics standpoint fared a bit better than our expectations. I think coming into the quarter, we had mentioned that we were wanting to be a little bit more conservative on our instrumentation assumptions. And so those did prove out To be conservative and they were slightly better, although we wouldn't really call it there was a budget flush activity in the 4th quarter. Speaker 300:35:10So as we look out to 2024, we do still believe our instruments will be pressured, for this year. And I think if you look at the overall assumptions, both the life sciences instruments and applied genomics will be down in the high single digit range for 2024 and that will put them closer in line to what their LRP is when you look over that at that over a 4 or 5 year period. Speaker 700:35:36Got it. Okay. And then Prahlad, can you talk about any momentum you're seeing in key accounts as it relates to Revenues ability to cross sell or realize commercial synergies following the divestiture and rebranding. I guess, are there any specific examples you can point to of how Remedy is making progress towards being a more effective strategic partner, specifically within Pharma? Speaker 200:36:04Yeah, Josh. I think, and I mentioned that during one of the healthcare conferences earlier in January, Our example with one of our most important customers that we talked about in the pharma side is how we are able to leverage our relationship both on the diagnostic and the life sciences side of the portfolio to not only license technology to them, but also provide the tools and capabilities and our service offering from the DX side that allows for being part of the journey of drug development for Our important customers all the way from preclinical research and licensing them the technology, Providing them the tools and capabilities that allows them to use and leverage that technology towards drug development And then being part of the journey with them through their development process as they take it through the regulatory approval processes and then further on Leveraging our global lab infrastructure from the omics side of the business to be able to follow-up those patients both for efficacy of the drug and for follow ups. So that sort of allows us initially when we were on the small molecule side in life science, Since our focus was on providing them with reagents and tools and instruments and pre in vivo imaging components, They just do their research. Speaker 200:37:30Now with the full expansion of our portfolio, it allows us to be with them from the start to when it gets to commercialization. Speaker 700:37:44Makes sense. Thanks, guys. Operator00:37:48The next question today comes from the line of Patrick Donnelly from Citi. Please go ahead. Your line is now open. Speaker 800:37:56Hey, good morning guys. Thanks for taking the questions. Probably one for Max on the margin side. Understand this year more flattish given the revenue outlook, it sounds like you guys are continuing to implement some cost plans there. Can you just talk about the confidence in that 75 bps expansion algorithm that you guys talked about at JPM and just this becoming that 30 plus percent margin business in the relative near term, what are the key levers you see And maybe just the process that went into revisiting that algorithm, did you guys want to set it more as a floor where you saw a clear path to on it, even the China piece sounds like you're chasing more profitability there. Speaker 800:38:32So maybe just kind of pull the curve back a little on the margins and again that algorithm you guys set? Speaker 300:38:40Yes, sure. Hey, Patrick. So as we step back and look at it from a margin perspective, I think that 75 basis points, it was taken down from the previous MRP of 75 to 100 basis points and that was mostly just attributed I think to the change in the top line assumptions. If you look at the assumption of the market on average is growing 4 to 6, we're a couple of 100 basis points better than that. That's going to drive natural operating leverage, just from a pure growth perspective. Speaker 300:39:09And so even in addition to that, I think where we have Confidence in sort of the margin expansion is really still the fact that we're still in the early innings of what the actual overall structure of this company should be given all the transformation, right, In terms of the number of acquisitions and integrating them into our core business and processes, as well as sort of working our way through all the stranded costs related to the divestiture. I think we have a lot of Stokes irons in the fire from an op margin expansion standpoint outside of just the natural volume leverage you would get. I think there is a high degree of confidence and in terms of your question in terms of the amount of conservative or whether it's a floor, I think we thought it was fair number that we can consistently deliver on with that expected growth algorithm. Speaker 800:39:55Okay. That's helpful. Prahlad, maybe just on China, it sounds like you guys talked a little about the immune ODX on an earlier question. But just in terms of this year, What you're seeing there, confidence both from the diagnostics and then the Life Science side, which is obviously a little more variable. Again, it sounds like you guys are making some changes in terms of going after a little more profitable business, but just the outlook in China, confidence in that region and what you're seeing here near term? Speaker 800:40:20Thank you. Speaker 200:40:24Yes, Patrick. I think nothing's Speaker 900:40:27changed in Speaker 200:40:27our view regarding China And that level of confidence is because of the portfolio differentiation. I mean, this is where I think it really comes down to a good understanding of the markets and the segments where we In that market, if you just look at the portfolio that we have built out over there, in terms of Life Sciences side, I think on the instrumentation side, we will continue to see some pressure, which is not very different from the other global markets. I think on the reagents side, we will continue to see it coming back. On the immunodiagnostics side, I think excluding the impact of what Max talked about for a small legacy business that helps us improve profitability, it is going to be on a growth trajectory. Newborn screening is going to get impacted, but we've got quite A few of our reagents that are awaiting an MPA approval and hopefully they will compensate for the pressure that we will see from the birth rate decline. Speaker 200:41:29So overall, I think it again comes back to the differentiation of our portfolio in China and outside of China. The lower it sort of risk mitigates our portfolio, both the exposure to the diagnostics, Life Sciences and the software market, which sort of in the longer run is going to be the competitive advantage that we will have. Operator00:42:00The next question today comes from the line of Andrew Cooper from Raymond James. Please go ahead. Your line is now open. Speaker 1000:42:09Hey, everyone. Thanks for the questions. Maybe first, I want to talk about margins a little bit more just for this year. You have modest top line organic growth. You've got 100 bps coming from price, some cost action. Speaker 1000:42:20So I guess, What are some of the counterpoints to prevent seeing maybe a little bit of expansion year over year in 2023? Or maybe asking it a different way, what's the threshold of revenue growth you need to see to actually see that margin expansion? Speaker 300:42:40Yes. Hey, Andrew. I think as we previously mentioned, the one dynamic you didn't mention for 2024 that we have already previously discussed is the fact that we will have variable costs that are returning in 2024 and I do not believe we are alone. And that dynamic as you've heard some of the others in the industry mention it. So I think from that perspective, that's really what's offsetting to your point the price and the structural cost actions that we have been taking. Speaker 300:43:03As you look out more cost actions that we have been taking. As you look out more longer term, I would say in a normal environment where you don't have that snap back of the variable cost, Even with, I would say, a lower growth than the LRP model assumes, I would anticipate us still being able to drive Margin expansion given some of my earlier points, but again, volume is a heavy driver when you think about it from a margin expansion standpoint. Speaker 1000:43:32Okay, helpful. And then maybe just one on the e commerce rollout. Any early feedback there or metrics you can share in terms of what the rollout has really looked like and whether it's more on the cost side, how we think about customer retention, sort of what the benefits are as we think about that moving beyond just the U. S. Rollout and globally longer term? Speaker 200:43:57Yes, Andrew. I mean, as we mentioned, we just rolled it out in mid December. So it's early days of the MVP and we are seeing good traction on it, from a customer flow perspective, the OUS launch is expected to be out in the early part of the second quarter. So while I would say it's 4 to 5 months ahead of schedule, it is still early days, looks promising. I think over the longer term, the benefit that we get out of it is not just synergies of being able to offer our comprehensive portfolio to our customers on a common platform, but obviously the synergistic opportunities that you get from a cost perspective or an OpEx perspective. Speaker 200:44:43So we are very excited about what we are hearing and seeing, but early days is the best way I would frame it for now. Speaker 1000:44:53Great. Appreciate it. I'll stop there. Thanks. Operator00:44:59The next question today comes from the line of Catherine Schulte from Baird. Please go ahead. Your line is now open. Speaker 1100:45:07Hey guys, thanks for the questions. Maybe first, your software and genomics lab businesses have faced headwinds over the last year due to some contract renewal and renewal and project timing dynamics. You mentioned those normalizing in 2024, but can you just walk us through the timing there and what kind of performance you expect from those businesses both for the Q1 and the full year? Speaker 300:45:33Yes, sure. Hey, Catherine. So as we look at maybe if we take a step back and just think about our guidance more holistically, I think the way to think about it is, we're assuming sort of a market down low single digits here in 2024. Reveny grows couple of 100 basis points above the market, so call that flat overall. And then the way we get to 2% is sort of that normalization of The software and omics business. Speaker 300:45:58So it's about a 200 basis points specific revenue tailwind for this year. In terms of the individual assumptions for those businesses, For the software business, it declined high single digits in 2023. We expect it to return to high single digits growth in 2024. And for the Omics business, that was down a little bit more than 30% in 2023 and we are expecting that to be flat in 2024, so essentially assuming none of those new contracts get signed, we continue to remain encouraged by the pipeline we have for that business. If we're able to close on some of those deals, that would be upside to what's assumed in the guidance case here. Speaker 1100:46:37Okay, great. And then how should we think about free cash flow in 2024, just particularly with those AES outflows coming back to you? Speaker 300:46:49Yes. So from a cash flow perspective, again, we are encouraged by the results that we had here in the Q4. For the overall year, that would have meant about roughly more than $400,000,000 once you normalize for those AES outflows. As we look to 2024, Our anticipation of free cash flow generation is about $450,000,000 The AES outflows will actually come back to us as inflows in investing Cash flow, if you add that to the $450,000,000 we are targeting to have about $600,000,000 of overall cash generation in 2024. Operator00:47:30Thank you. The next question today comes from the line of Vijay Kumar from Evercore ISI. Please go ahead. Your line is now open. Speaker 1200:47:40Hi guys. Thanks for taking my question. Good morning to you Prahlad. Maybe my first one for you on This Q1 organic guidance assumption of down mid singles, you did call it comps. You look at Q4 down low singles. Speaker 1200:47:56Most of your peers are assuming first have to be similar to Q4 jump offs. So maybe just talk sequentially Why perhaps what's driving that change from down low singles to down mid singles? Speaker 200:48:13Yes, I think as we talked about, we are from a Q4 to a Q1 perspective, a lot of it is obviously the comps that we had from last year. So it is more an impact of that than anything else. And I think as Max laid out the cadence of the calendar for the year, There is nothing outside of that, that I would say. We do have some pressure from reproductive health, especially in China. And on the instrument side, we will see some impact of that. Speaker 200:48:43But more than anything else, it is just timing is where I would allocated to the impact that we see on 1Q versus anything else. Yes. Speaker 300:48:53I mean, the only point I'd add to that, Vijay, you mentioned it yourself, right? Most are saying that the first half will be similar to what they had in Q4 and that's what I just mentioned previously, right, that our first half assumption is down low single digits, which is in line with what we just printed for the Q4. Speaker 1200:49:10Understood. And Max, maybe One for you, if your gross margins in Q4 down sequentially, so what happened in Q4? And When you think about fiscal 2024 guide, is the guide assuming gross margins to be flattish up or down versus fiscal 'twenty three. Speaker 300:49:31Yes, sorry, Vijay, I might have missed the first part of your question. I think you were mentioned on Just asking the question on gross margin for this year. So in the Q4, the gross margin was about 60%. It was down quarter over quarter as we had some mix dynamics play out in the Q4. As we look to full year 2024, we expect gross margin to be roughly flat year over year And we expect it to build as the year goes on as we get increased volume leverage throughout the year. Speaker 1200:50:01And so it's essentially the mix improves, Max, is that the assumption like what's driving the step up from Q4? Speaker 300:50:10Yes, I think from Q4 to Q1, it's relatively similar. We're expecting kind of a similar mix dynamic from Q4 to Q1. As the rest of the year It is mostly a volume leverage story as opposed to a massive change in mix dynamics. Speaker 1200:50:25Fantastic. Thanks guys. Operator00:50:31The next question today comes from the line of Dan Brennan from TD Cowen. Please go ahead. Your line is now open. Speaker 600:50:40Great. Thanks for the questions, guys. So ImmunoDx, another solid quarter in year. Speaker 200:50:46Can you just give us a Speaker 600:50:46sense of kind of What's driving the strong growth and like what's the range of outcomes we can expect for 2024? Speaker 200:50:56And then I think again, as I've talked about earlier, it is the differentiated portfolio of the high end euro immune tests that we have in China That allows us to be in the face of limited competition that we see in that marketplace and that has innovation pipeline has worked for us and then we expect that to continue as we look forward. Speaker 600:51:26Got it. Okay. Maybe on pharma, I know you kind of talked about it throughout a little bit, but it key drag at Q3. You guys talked about instruments still under pressure here, maybe from a post COVID high. Just can you speak to some of your discussions with pharma? Speaker 600:51:41What do we expect this year? Just kind of any more color on kind of what you're hearing there? Thank you. Speaker 200:51:49Yes, Dan. I think on the instrument side or on the capital side, I think we will continue to see some pressure or at least the current trend we expected to continue in the first half of the year. The benefit again that allows us is that the reagent side of the portfolio, once that starts stabilizing and coming up in the second half of the year, That's what the assumption that we have in our current forecast allows us the confidence that we would look. Overall, as we see pharma, I continue to believe that this is a temporary growth in the marketplace and I think it will continue it will come back to what we have seen is normal pattern of mid single digit growth in the market over the past several years. Speaker 300:52:43Got it. Thank you. Operator00:52:47The next question today comes from the line of Yves Bernstein from Bernstein Research. Please go ahead. Your line is now open. Speaker 900:52:57Good morning. Thanks a lot for the questions. First one, you said that you've already taken structural cost measures so far this year and you'll be taking additional cost actions in cost actions in 2024. Can you just give us some more color on what those actions are and what's giving you confidence and maybe the ability to achieve those benefits in this Speaker 300:53:23So from a structural cost action perspective, the easiest way to think about it is really just rightsizing the company given all of the transformation, Whether that's the integration of the acquisitions, which I mentioned, we're still what we would consider in the early to mid innings from a process standpoint. And then it's working our way through the stranded costs from the divestiture. So that's really what's driving the structural cost actions. In terms of the confidence, those actions have already been taken place and communicated. There's a little bit of timing in terms of When the actual cost comes out throughout the course of the year, but those actions have more or less already been executed and it's just a matter of timing at this So we have, I would say, a high degree of confidence in those for this year. Speaker 900:54:11Great. Thank you. And then you just talked about integration of your acquisitions. You said Still early to mid innings. But you also shared an example of how you brought Biolegend together with other parts of your business to do something really cool. Speaker 900:54:34Where are you really against your synergy target of $100,000,000 in year 5, you're 2 5ths of the year 2 5ths of the way through. Where would you put yourself on that scale? Speaker 200:54:49Yes, I'm not good morning, I don't think I'm going to quantify as to what The dollar amount of how much synergies we are seeing, the intent of what we provided as an example is How we are starting to see not just commercial synergies from the full portfolio, but operational and technological synergies. I think as Max said, I would say we are still in the early to mid innings Of the opportunities that we see from integration of the acquisitions, keep in mind, 2 of our acquisitions, Biolegend and EUROIMMUN are 2 of our strongest and fastest growing businesses. And I think the opportunities that they provide are crown jewels in our portfolio and we expect them to continue to perform well. Our intent is how do we support those businesses And how do we leverage the opportunities that we see across the portfolio with them? Speaker 900:55:51Great. Thank you. Operator00:55:55Our final question today comes from the line of Luke Sergos from Barclays. Speaker 1300:56:05So real quick on the 1Q Margin target, you said like a few 100 basis points lower than your full year. So I assume that's around like 25%. Can you talk about Even though it's the growth and everything looks a little bit like 4Q, can you just talk about what's really driving that decel and then kind of where you're going to get the margin uplift throughout the year on that steep ramp? Speaker 300:56:36Yes. Hey, Luke. So I think maybe just let's tackle the margin question first to kind of lead with that. So look, I don't think your math is that far off from Q1. I think we've given you the pieces below the line in Q1 that you're going to get to roughly that number. Speaker 300:56:51As you look at comparing that to Q4, I would say the 2 main really the main driver of that is just a volume stepped down from a top line perspective. If you look at the actual overall gross margin percentage, it's roughly flat quarter over quarter. OpEx costs are similarly in line quarter over quarter. And so from that standpoint, I don't think really much has changed. Again, as you then look at the volume ramp over the remainder of the year, as we mentioned, 1, you're going to have the timing of the structural cost actions coming into play. Speaker 300:57:23And the second piece is you're going to have volume leverage as the year builds. So that's how I would think about it from a margin perspective. In terms of the slowdown from an organic growth perspective between Q4 to Q1, I think we've mentioned part of that is definitely comp driven and the biggest piece of that is going to be on the immunodiagnostics business outside of China. Outside of China in the first half last year, immunodiagnostics grew in the high teens. We've always said it should be sort of a low double digit. Speaker 300:57:52And so there is just some normalization there on a 2 year stack for immunodiagnostics business outside of China. Speaker 1300:57:59Yes, great. Thanks. I was just referring to the 4Q to 1Q kind of just the similar you have a pretty steep decline there in the margin. I got The core commentary. And then I guess on the software piece, you guys have talked about converting a lot of these customers more to SaaS space and that's kind of aiming to reduce the lumpiness in the orders and talk about the progress that you're seeing there. Speaker 1300:58:25And On the non SaaS piece, can you talk about what the orders look like and if they're inflecting because as you talked gave that 2% framework prior, you were talking about just if software is not a headwind next year or the way that the contracts come in, that will just be at least 100 basis points of lift? Speaker 300:58:47Yes. So, Menel, maybe start with your second question first, Luke, so as I mentioned, software business was down high single digits in 2023. It should be moving to up high single digits. That's what's assumed in our guidance here for 24. That is roughly 125 basis points to the overall company from an organic growth perspective. Speaker 300:59:09And so as you look at that dynamic, it's really driven by this contract renewals. Again, that's a business that has upper 90s percent renewal rate. And so most of the contracts we know are coming due and I would say have a high degree of confidence in our ability to deliver on our 2024 expectations. And then to your first question on sort of the SaaS transition, I think we continue to make really good progress. We view the transition to SaaS as actually a differentiator For us versus our peers, we believe we are ahead of them in terms of that transition. Speaker 300:59:41And so although that might create a little bit of noise from a revenue recognition standpoint, It is the right thing to do for the business and we think our SaaS products are going to help us actually take share from our competition. Yes. And Luke, in the longer Speaker 200:59:52term, it Tom, it definitely help us increase revenue and reduce our volatility for that business, which I think is another one of the opportunities that the Software business provides us from a differentiation perspective. Speaker 1301:00:09Great. Thank you. Operator01:00:13This concludes today's question and answer session. I'd like to pass the call back over to Steve Willoughby for any closing remarks. Speaker 101:00:22Thank you. Thanks for your interest and questions today, and we look forward to further discussions over the coming weeks. Have a good day. Bye bye.Read moreRemove AdsPowered by