NYSE:AVTR Avantor Q1 2024 Earnings Report C$41.80 +0.23 (+0.55%) As of 04:00 PM Eastern Earnings HistoryForecast Keyera EPS ResultsActual EPSC$0.22Consensus EPS C$0.20Beat/MissBeat by +C$0.02One Year Ago EPSC$0.29Keyera Revenue ResultsActual Revenue$1.68 billionExpected Revenue$1.68 billionBeat/MissMissed by -$2.71 millionYoY Revenue Growth-5.60%Keyera Announcement DetailsQuarterQ1 2024Date4/26/2024TimeBefore Market OpensConference Call DateFriday, April 26, 2024Conference Call Time8:00AM ETConference Call ResourcesConference Call AudioConference Call TranscriptSlide DeckPress Release (8-K)Quarterly Report (10-Q)SEC FilingEarnings HistoryCompany ProfileSlide DeckFull Screen Slide DeckPowered by Keyera Q1 2024 Earnings Call TranscriptProvided by QuartrApril 26, 2024 ShareLink copied to clipboard.There are 14 speakers on the call. Operator00:00:00Good morning. My name is Emily, and I'll be your conference operator today. At this time, I would like to welcome everyone to Avantor's First Quarter 20 24 Earnings Results Conference Call. After the presentation, there will be the opportunity for you to ask any I will now turn the call over to Christina Jones, Vice President of Investor Relations. Ms. Operator00:00:24Jones, you may begin the conference. Speaker 100:00:26Good morning. Thank you for joining us. Our speakers today are Michael Stubblefield, President and Chief Executive Officer and Bren Jones, Executive Vice President and Chief Financial Officer. The press release and a presentation accompanying this call are available on our Investor Relations website at ir.avantorsciences.com. A replay of this webcast will also be made available on our website after the call. Speaker 100:00:58Following our prepared remarks, we will open the line for questions. During this call, we will be making forward looking statements within the meaning of the U. S. Federal securities laws, including statements regarding events or developments that we believe or anticipate may occur in the future. These forward looking statements are subject to a number of risks and uncertainties, including those set forth in our SEC filings. Speaker 100:01:26Actual results might differ materially from any forward looking statements we make today. These forward looking statements speak only as of the date that they are made. We do not assume any obligation to update these forward looking statements as a result of new information, future events or other developments. This call will include a discussion of non GAAP measures. A reconciliation of these non GAAP measures can be found in the press release and in the supplemental disclosure package on our Investor Relations website. Speaker 100:02:00As a reminder, on January 1, 2024, we transitioned from our former regional segment structure to 2 global operating segments, Laboratory Solutions and Bioscience Production. Our Q1 2024 results are presented on this basis. With that, I will now turn the call over to Michael. Speaker 200:02:24Thank you, CJ, and good morning, everyone. I appreciate you joining us today. I'm starting on Slide 3. The year is off to a good start as we delivered 1st quarter revenue in line with our guidance with reported revenue of $1,680,000,000 and organic growth of minus 6.3 percent. As anticipated, market conditions remain similar to the 4th quarter. Speaker 200:02:49Our team continues to execute well as evidenced by our margin and profitability outperformance with adjusted EBITDA margin of 16.8% and adjusted EPS of $0.22 As Brent will outline in his section, our margins were driven by pricing, favorable product mix, disciplined cost management and accelerated realization of savings from our multi year cost transformation initiative. We also generated $107,000,000 of free cash flow in the quarter. Consistent with our current capital allocation priorities, we paid down approximately $170,000,000 of debt and continue to target an adjusted net leverage ratio below 3 times. As CJ noted, our new operating model became effective in January. Our new business segments enhance our focus on customers' needs in the lab and production environments, position us for accelerated long term growth and unlock significant operating efficiencies. Speaker 200:03:46We are early in our journey, but are out of the gate strong and are already realizing benefits from the new model. During the Q1, we aligned our organization with the new business segments and initiated several work streams to optimize the Avantor customer experience. Our commercial intensity and the relevance of our workflow solutions resulted in multiple competitive wins and contract renewals with biopharma, healthcare and education and government customers. As part of our innovation strategy, we enhanced our offerings for cell engineering, gene therapy and synthetic biology applications through supplier partnerships and proprietary innovation. We are seeing strong customer response to recent proprietary new product introductions, including our viral inactivation solutions launched earlier this year and our integrated mixing systems and fluid handling assemblies, which are delivering critical efficiency and quality improvements to our bioprocessing customers. Speaker 200:04:45We also advanced our multi year cost transformation initiative, including footprint optimization, organizational efficiency, go to market and procurement savings. Our disciplined execution enabled us to accelerate the realization of some savings into the Q1, contributing to our margin and profitability outperformance. We continue to be encouraged by the positive trends we are seeing in our end markets. In laboratory solutions, biotech funding is improving and our large pharma customers are engaging with us on new projects that are driving an increase in our commercial opportunity funnel. Core diagnostic testing has returned to growth and QA QC workflows in the applied markets have been relatively stable. Speaker 200:05:31Additionally, internal and external surveys suggest that inventory health continues to improve. Collectively, these factors resulted in a sequential increase in sales of our consumables and chemicals offerings, both key drivers of our long term growth. In bioscience production, the bioprocessing end market remains healthy with a robust pipeline of new therapies, a favorable regulatory landscape including 3 new cell and gene therapy approvals in the quarter and strong patient demand. Importantly, we saw another quarter of sequential improvement in our bioprocessing order rate. Within healthcare, medical implant procedure rates continue to be positive and overall demand within the semiconductor end market has rebounded from the lows we experienced in 2023. Speaker 200:06:19Consistent with our in line revenue performance in the quarter, these encouraging market signals have not yet translated into an inflection in aggregate sales levels as pockets of inventory destocking and cautious customer spending, notably in equipment and instrumentation continue to impact demand. We believe our current approach to guidance, which assumes a continuation of current market conditions is appropriate and we are reaffirming our full year outlook. Should a meaningful market recovery take place within the year, that would present upside to our guidance. Before I turn it over to Brent, I'd like to share a few takeaways from the quarter, which show that our model is working. 1st, momentum in our consumables portfolio, representing the vast majority of our revenue, largely offset industry wide weakness in capital driven equipment and instrumentation sales and translated to outperformance in margins and EPS. Speaker 200:07:142nd, our BAW processing offerings are strategically positioned to benefit from attractive end market fundamentals and we outperformed our bioprocessing guidance and realized another sequential step up in bioprocessing orders. Finally, we are taking action to strengthen performance and drive productivity. We made meaningful progress in transforming our operating model and we are ahead of plan on our cost transformation initiative. With that, I'll now turn it over to Brent to walk you through our Q1 results in more detail. Speaker 300:07:46Thank you, Michael, and good morning, everyone. I'm starting with the numbers on Slide 4. Reported revenue was $1,680,000,000 for the quarter, declining 6.3% on an organic basis. In our Laboratory Solutions segment, sales trends were generally similar to the 4th quarter levels. We are seeing nice momentum in consumables and chemicals offset by softer than expected demand for equipment and instrumentation. Speaker 300:08:12Our Bioscience Production segment performed modestly ahead of expectations driven by upside in bioprocessing and biomaterials. Adjusted gross profit for the quarter was $572,000,000 and adjusted gross margin was 34%. Year over year, our adjusted gross profit was impacted by lower sales volume and unfavorable product mix, partially offset by productivity. Adjusted gross margin improved nicely on a sequential basis. This was largely due to pricing and the positive mix impact from strength in higher margin consumables and weakness in lower margin equipment and instrumentation. Speaker 300:08:53Adjusted EBITDA was $283,000,000 and adjusted EBITDA margin was 16.8%. Adjusted operating income was $258,000,000 at a 15.4 percent margin. Year over year, our adjusted EBITDA and adjusted operating income performance were impacted by lower sales volumes and unfavorable mix. While adjusted EBITDA and adjusted operating income were down sequentially, primarily from the reset of incentive compensation, our margins were well above our expectations. This outperformance was driven by better than expected mix and the accelerated impact of certain cost transformation initiatives up and down the P and L. Speaker 300:09:38Net interest expense and adjusted tax expense were in line with our expectations, resulting in adjusted earnings per share above expectations at $0.22 for the quarter. Moving to free cash flow, we generated $107,000,000 in the quarter. Our free cash flow performance was impacted by costs associated with our cost transformation initiative. Our adjusted net leverage ended the quarter at 4 times adjusted EBITDA. The slight uptick in leverage was driven by a reduction in our trailing 12 months adjusted EBITDA. Speaker 300:10:13As Michael noted, we remain focused on deleveraging and pay down approximately $170,000,000 of debt in the quarter. In April, we favorably repriced about $770,000,000 of term loans, reflecting a supportive financing market and strong demand for our debt. Slide 5 outlines our segment performance. Launching our 2 new segments has been a critical strategic move to sharpen our focus on accelerating growth and streamlining organizational accountability. It also has the benefit of unlocking significant savings. Speaker 300:10:51In laboratory solutions, which represents roughly 2 thirds of our revenue, we provide an industry leading platform of products, services and digital solutions to support our customers' research, diagnostic and QC workflows. Laboratory Solutions revenue was $1,160,000,000 for the quarter, declining approximately 4.5% versus prior year on an organic basis. Our consumables and chemicals, both proprietary and third party, showed sequential growth performing better than our expectations. However, momentum in these categories was offset by lower equipment and instrumentation sales in each of our end markets. Adjusted operating income for laboratory solutions was 100 and $48,000,000 for the quarter, representing a 12.8 percent margin. Speaker 300:11:45Year over year adjusted operating income decline was driven by negative sales volume. Sequentially, we saw favorable mix due to strength in higher margin consumables and chemicals and weakness in lower margin equipment and instrumentation. However, despite the mix impacts on gross profit, adjusted operating income declined due to the impact of our annual incentive compensation reset. This expense increase was partially offset by savings from our cost transformation initiative. Our Bioscience Production segment represents about 1 third of our revenue and over 45% of our enterprise profitability. Speaker 300:12:25This business supports customers' production platforms by providing high purity process ingredients and single use solutions for bioprocessing, ultra high purity silicone formulations for medical implants and custom solutions for semiconductor and advanced technology applications. Bioscience production revenue was $523,000,000 representing an organic decline of approximately 10%, slightly ahead of our expectations for the quarter. Bioprocessing was down low teens on an organic basis versus our expectations of down mid teens. Adjusted operating income for bioscience production was $127,000,000 for the quarter, representing a 24.3 percent margin. Year over year adjusted operating income declined as a result of lower sales volume. Speaker 300:13:19On a sequential basis, despite revenue performance exceeding our expectations and solid mix, adjusted operating income declined modestly driven by the expense side. Like laboratory solutions, this was largely due to our incentive compensation reset. However, these expense accruals were partially offset by savings from our cost transformation initiative. Altogether, a solid quarter in both segments. Moving to the next slide. Speaker 300:13:50Slide 6 shows our full year 2024 guidance. As referenced throughout the call today, we see encouraging signs in our end markets. However, it is still early in the year and the operating environment remains dynamic. As Michael indicated, we believe it is prudent to base our guidance on a continuation of current market conditions and we are reaffirming our full year guidance as outlined last quarter. This includes organic revenue growth of negative 2% to +1%, adjusted EBITDA margin of 17.4% to 17.9% and adjusted EPS of $0.96 to $1.04 We also expect free cash flow performance of $600,000,000 to $650,000,000 excluding any cash costs associated with our cost transformation initiative. Speaker 300:14:46On a segment basis, we expect low single digit growth in laboratory solutions and a mid single digit decline in bioscience production. A couple of comments on phasing. As laid out at the beginning of the year, we expect to generate 49% of our full year revenue in the first half and 51% in the second half. This leads to Q2 organic revenue growth of approximately negative 3.5% to negative 1.5%. The modest sequential increase in reported revenue dollars as we progress through the year is driven by pricing phasing, lot of seasonality, timing of known orders and nominal billing day adjustments. Speaker 300:15:31In terms of profitability, we expect our Q2 gross margin per seige to be similar to Q1. Adjusted EBITDA margin should improve by about 25 to 50 basis points sequentially, driven by the impact of our cost transformation initiative. Our ability to accelerate our transformation savings into the Q1 flattens the margin ramp needed to achieve our full year plan. We are executing well against the transformation plan evidenced by the nice pull forward of savings into Q1. We are solidly on track to achieve at least $75,000,000 of in year savings in 2024. Speaker 300:16:10With that, I will turn the call back to Michael. Thank you, Brent. Speaker 200:16:15With our new operating model in place, we're well positioned to realize accelerated long term growth and unlock significant operating efficiencies. We are seeing the benefits of our new business segments in driving commercial momentum with our research and production customers as well as enhancing our operational rigor and forecasting. I am pleased with the progress we have made on our multi year cost transformation initiative. We are ahead of plan and are already seeing the impact in our cost structure and margins. As the market recovers, we will be well positioned to enhance the conversion of top line growth to improve bottom line profitability. Speaker 200:16:53I'd like to close by thanking our Avantor associates for their steadfast dedication to serving our customers and to creating a better healthier world. Their contributions enabled us to make meaningful progress on our business transformation and deliver on our operating plan. I will now turn it over to the operator to begin the question and answer portion of our call. Operator00:17:36Our first question today comes from the line of Michael Ryskin with Bank of America. Please go ahead. Speaker 400:17:44Great. Thanks for taking the question guys. Michael, I want to start with one for you if I could. You talked throughout the call about consistent market conditions, no real change there. But you also did call out some encouraging market signals that just haven't translated to sales yet. Speaker 400:17:58When we think about Avantor, we typically think of it as being a relatively fast order cycle. So could you just help us understand if the market signals do start to flow through, if the market conditions do improve, sort of like what's the lag between when you start seeing that and when it shows up in the revenues? And obviously, there could be differences in different end markets, maybe touch on semis, bioprocessing, anything else? Thanks. Speaker 500:18:21Yes. Good morning, Michael. Thanks for the question. Yes, you're right. We are, as we said in the script, recently encouraged by what we're seeing in the marketplace. Speaker 500:18:31A lot of the leading indicators, whether it's funding, improvements in order books particularly in bioprocessing, customer activity, building up pipelines, approvals of new drugs. I think there was even another approval this morning coming out of the pipeline. So a lot to like about the setup for our end markets. We do have a relatively short order cycle business model as we've talked about previously within our lab solutions segment. That's more of a book and ship type of business. Speaker 500:19:06So we kind of take orders real time and would anticipate shipping those typically within a 24 to 48 hour period. So as these signals translate into increase in orders and ultimately into revenue, we'll see that pretty much real time. Bioscience Production segment tends to be driven by a little bit longer lead times that have normalized post the pandemic. We're on average probably 2 to 3 months out in terms of being able to satisfy a customer order there. And so we'll see that inside of a quarter if at most maybe with a 1 quarter lag. Speaker 400:19:51I was on mute. Thanks. That's really helpful. And then quick follow-up. You did call out in Lab Solutions a little bit of pressure in equipment instrumentation, realize it's a very small part of your overall mix, but anything specific you can touch on there, whether it's big pharma or biotech that's still a little bit lagging? Speaker 400:20:09And just there, you would have a little bit better visibility. So do you think that's just a timing thing to start the year? Or is that budget still being constrained? Thanks. Speaker 500:20:22So I'd probably highlight a couple of things here, Michael. Firstly, as you suggest, E and I for us is a relatively modest part of the business, about 15% of our overall revenue, a little bit more pronounced in our lab solutions segment. We are seeing kind of industry wide pressures for purchase of equipment and instrument driven by project delays and extended times to get projects approved and a little bit more cautious approach to just getting capital related purchasing items approved real time here. It was a slow start to the year and that which isn't unusual coming out of year end where folks will typically try to buy ahead for some of their demand. But unlike a normal year where you'd see that kind of pick up as you move through the quarter, we didn't really see that acceleration. Speaker 500:21:16And so unlike the momentum that we saw in our consumables portfolio where both in consumables and chemicals both in both of our segments where we saw a nice acceleration coming from Q4 to Q1, we didn't really see that in the E and I piece. I'd probably say it's probably most notably in biopharma is where we see it, but we probably look at it across all of our end markets at some level. Speaker 400:21:47Great. Thanks so much. Operator00:21:53The next question comes from Dan Leonard with UBS. Please go ahead. Speaker 600:21:59Thank you. I have a follow-up on that last question. Michael, possible you could frame the magnitude of the decline in E and I in the quarter? And I ask because it's not a big part of your business, but it seems to have fully offset the outperformance in recurring within your lab business specifically? Speaker 700:22:22Yes. I guess I'd say probably a couple Speaker 500:22:23of things, to maybe lay some tracks for you on that. If I look at our Bioscience Production segment as an example, you saw the modest outperformance that we drove there reflecting a bit of momentum in bioprocessing in certain our biomaterials business, our electronics business has recovered from the lows that we experienced in 2023. But again, was somewhat modest, but encouraging nonetheless, but nothing that we would consider to be an inflection point. And we have relatively modest equipments and instrumentation exposure in that segment. Now if I look at the Lab Solutions segment by comparison, we have a bit more exposure there. Speaker 500:23:07It's probably on the order of 20% of the revenues or thereabouts would be in the equipment and instrument space. So reasonably meaningful. We did see similar upside to our consumables and chemicals growth is what we saw in our production segment that was basically fully offset by the sequential weakness in E and I. So although we are a consumables driven business, roughly 15% of our overall sales are linked to equipment and instrumentation. So weakness certainly does get reflected. Speaker 500:23:44Fortunately, with the consumables portfolio and the higher margins that are associated with that part of the portfolio, you see the impact on mix. And as I highlighted in my script, we really focus here on the consumables business and I'm quite encouraged by, A, not only the momentum on the top line, but the flow through of that to margins on the bottom line and you see that helping with some of the outperformance on the margin line. Speaker 600:24:14Appreciate that. And then as a follow-up, you mentioned that bioprocessing is doing a bit better, but not yet in inflection. I was hoping you could elaborate on the performance of any of the leading indicator product categories within bioprocessing and what they're telling you? Thank you. Speaker 500:24:33We are quite encouraged to see a second straight quarter here of sequential improvement in bioprocessing order book trends. And maybe adding to our encouragement here is we saw the pace of step up here accelerate in Q1 even a bit more than what we saw in Q4 and it's widespread. We're seeing it both in the Process Ingredients, excipients part of our business as well as encouraging in our single use platform. We've talked over recent quarters a fair bit about the pickup in engineering activity, which is certainly a story will play a nice leading indicator for our single use business, hadn't yet translated into an order book. It feels like we're starting to see that start to translate quite nicely. Speaker 500:25:25And it's with large pharma, it's with CDMOs and so we like how broad the pickup appears to be at the moment. But to your point, and consistent with what we've said and how we've guided, we've not yet realized that pickup in the order book in a meaningful change in our sales trends. And so our guidance reflects a continuation of current conditions. But certainly, a couple of straight quarters here where we're pretty encouraged. Speaker 800:26:00Thanks, Michael. Operator00:26:06The next question comes from Dan Brennan with TD Cowen. Please go ahead. Speaker 700:26:14Great. Thank you. Thanks for the questions. Michael, maybe just on the lab solutions business since that came in a bit weaker here. Just can you discuss kind of how the quarter played out? Speaker 700:26:24Any versus expectations kind of what trended a little bit lighter than what you expected and what gives you confidence in kind of the full year there? Speaker 500:26:34Yes. So I think we called for roughly low single digit decline in the quarter. It came out maybe a point or so weaker than that, really all on the back of the E and I trends that we've discussed here on the call and in the early questions. The 80% of that segment that's consumables, chemical services actually performed better than our expectations. And we're starting to see some nice acceleration there, which I think is reflective of the destocking trends that we're seeing and the improvement of inventory health as well as just a good indicator of funding and activity levels, engagement with our customers across the board. Speaker 500:27:22So the 2 largely offset one another. But yes, the weakness there was really driven by continued cautious approach to capital purchase spending there in the equipment and instrument category. Speaker 700:27:42And then maybe a follow-up for Brent, just in terms of the nice progress on the cost saves and the nice margins in the quarter, you guys are maintaining the full year guide. Just walk through a little bit of like what drove the upside in the quarter there? And did that give you potential upside bias to how you think the full year plays out? Speaker 300:28:02Yes, absolutely. Thanks for the question. Obviously, the cost transformation has been a huge focus for us. And Michael noted our 4 pillars organizational efficiency, footprint optimization, go to market and procurement. Unsurprisingly given that they're sort of shorter cycle and actions, we outperformed on the organizational efficiency and the procurement side there. Speaker 300:28:26A lot of this is frankly unlocked by the new segment structure, which really allows us to get the efficiencies of the new model and frankly that also drove to the procurement piece of it. In terms of look on the full year there, let's say, we are gratified with the strong start. We worked really hard at that and we're going to continue, But it's early in the year and there are a lot of moving pieces. So I think let's hold it $75,000,000 is a good assumption for the year. But if we get acceleration, certainly the next time we talk to you, we'll let you know. Operator00:29:08The next question comes from Luke Sergott with Barclays. Please go ahead. Speaker 900:29:14Great. Thanks, guys. Just wanted to follow-up on that last question. And so when we're thinking about the pacing of the cost out structure across the margins for the rest of the year, can you help give us a little help on the modeling side and then by segment? And then the blend there between the gross margin and operating and SG and A? Speaker 300:29:39Look, I think that's 7 questions, but I'll do my best. So, yes, so on the progression there, again, nice outperformance and transformation in Q1. We'll see a meaningful uptick in transformation saves in Q2 and then that will increase somewhat ratably in Q3 and Q4 unsurprisingly just due to the timing of actions particularly on org efficiency but as well as procurement and the others. And then we do starting in Q2 have merit coming in so that's not a material headwind against it. So you won't see a dramatic change in the SG and A line in Q2. Speaker 300:30:20You will see some goodness with additional actions then in the back half of the year. We're not breaking the transformation down really by segment here. It's unlocked by that, but we're not going to make external comments there. But then it just that will lead to kind of as you get that ratable improvement there as well as as you get that ratable improvement there that will just nicely lift EBITDA margin there When you do the math on keeping the full year guide and we really expect gross margins to be pretty consistent based on what we're seeing. So you manage those together, I would think of that in a pretty linear basis honestly for how the year lays out. Speaker 900:31:01All right. That's helpful. And then so on the BioSecure Act, what are you guys hearing from your customer CDMO customers on that side? And then any exposure to WuXi and that complex that might provide some near term disruption? Or how are you guys thinking about that? Speaker 500:31:22Yes. Look, we obviously are monitoring the developments with that legislation pretty closely. Obviously, the final details are still be determined and we're not in any better position than anybody else probably to try to anticipate where that's going to land and how it ultimately gets implemented. But what I would say is we benefit from a global presence and certainly are well positioned to support our customers through our collaboration model to ensure that we can help them through whatever implications of that act might mean for them. We don't anticipate any particular meaningful at an aggregate level for us. Speaker 500:32:02We don't have a lot of exposure into China specifically. And then on the maybe on the U. S. Side, we're obviously well positioned with both CDMOs as well as the OEMs. And so I think from our perspective, there end up you could end up see some puts and takes between specific accounts. Speaker 500:32:22But as deeply as embedded we are across this space, I think we view us as a solution provider here that you'll be able to help our customers with any implications here. Speaker 900:32:36Great. Thanks. Operator00:32:42The next question comes from the line of Vijay Kumar with Evercore ISI. Please go ahead. Speaker 800:32:50Hi, Michael. Good morning and thanks for taking my question. I guess my first question, Michael, on consumables, I think you said improved sequentially. Can you split that out between bioprocessing and lab solutions? Were consumables up in both segments sequentially? Speaker 800:33:10Was it flattish? I think on the order side for bioprocessing, you did mention sequential growth. Could you quantify that was book to bill perhaps north of 1? Speaker 500:33:24Yes, let me take the two questions there. So consumables are pervasive across both segments as you noted and encouraging that we saw sequential improvement in both segments. We probably have less than, I don't know, 5% of our revenues in our production segment are equipment and instruments. And so that's largely a consumables play for us in that segment. And you saw the modest beat to expectations there and that's all linked to the consumables trends that we did see. Speaker 500:33:56And similarly, although a bit more equipment and instrument exposure on the lab segment, we saw a similar upside from the consumables part of that businesses as well. So again, I think that speaks to just the power of our model. I indicated in my remarks that I think this quarter is actually a really good illustration of how our model is working, where you see the activity levels, inventory health improving, leading to stronger pull through of our core portfolio here, which are bringing the higher margins with it, which led better mix in the quarter and the higher margins as you see. So really like how the model worked in the quarter. Relative to your second question there around the impact of some of the insights there on our bioprocessing order book. Speaker 500:34:53I don't think we've historically discussed a book to bill. We don't find that to be particularly meaningful in our business. But what I can say is, we're now a couple of straight quarters here of sequential improvement. The The acceleration or the improvement that we saw in Q1 was actually even a bit more than what we saw in Q4. So the rate does seem to be picking up some momentum here. Speaker 500:35:19It's broad based, it's across not only our chemicals, process ingredients, excipients categories, but also across our single use platform, which as I said before, we think is maybe the first sign that how the engineering drawing activity we discussed last year is now starting to work its way through the pipeline. We've talked a lot in these forums, Vijay, about our best in class bioprocessing performance, both in terms of absolute revenue performance. And we think with the performance in this quarter, we were as good or better than anybody out there. I think you could probably say the same about the order book trends that we saw. I mean, obviously, we're looking at a lot of the same things that you are. Speaker 500:36:09And I would say we're very pleased with the development of our order book. And I think you could be safe in assuming that it was as good if not better than anything that you've seen reported so far. Speaker 800:36:23That's very helpful, Michael. Maybe one more on instrumentation. Anything on phasing, Michael, in the quarter on instrumentation? Were there any days impact or holiday impact Easter, etcetera? I'm just trying to think instrument was down consistently throughout or anything happened late in the quarter? Speaker 500:36:46The only thing meaningful intra quarter dynamic that I would point out was we got off to a slow start in the year for equipment and instruments, which wasn't such a huge surprise. That's not unusual coming into a new year, folks are had satisfied probably a lot of their near term needs at year end using whatever budget they had, getting budget set for the coming year. What you normally then see though is a pickup and acceleration as you move through the quarter. We didn't see it. It was weak all quarter as it turned out. Speaker 500:37:20So that's probably the only intra quarter dynamic that I would highlight for you. Speaker 1000:37:26Thank you, guys. Operator00:37:31The next question comes from Jack Meehan with Nephron Research. Please go ahead. Speaker 1000:37:39Thank you. Good morning. Michael, could you talk a little bit about the academic end market? It looks like it took a little bit of a step back with the low single digit decline. Heard some it's probably similar to what we're seeing at others. Speaker 1000:37:54But can you just talk about what you're seeing in terms of marketing conditions there? Speaker 500:37:59I'd say a couple of things, Jack. Firstly, you're right. We were down, I think, low single digits in aggregate for that education and government end market. Probably the more important part for us and consistent with what we've been seeing actually over the last several quarters in 2023 was our ongoing share wins and momentum in large academic institutions. And despite that end market overall for education and government being down, our large academic customers were up again in the quarter. Speaker 500:38:42So continued momentum and nice activity levels and that's I highlighted in my prepared remarks, some of the customer wins, renewals and share gains. Certainly, this academic setting, particularly in the U. S. Is a large focus for us and pleased to see yet another quarter of growth. Speaker 1000:39:05Great. And then for Brent, can you just lay out for us on the segment level what the expectations are for organic growth in 2Q? I'm trying to tease out like what's comps versus kind of recovery as we phase through the year? Speaker 300:39:25Yes. As we think about Q2 there, as we noted, we expect lab solutions to be down low single digits and BPS to be down sort of low single digit, mid single digit, which and within that bioprocessing down sort of mid single digit, high single digit. Speaker 1000:39:47Okay. Thank you. Speaker 700:39:50Yes. Operator00:39:54The next question comes from Doug Schenkel with Wolfe Research. Please go ahead. Speaker 1100:40:01Hey, good morning guys and thank you for taking my questions. First, just on geographic trends, anything you can share across the business, capital versus recurring, segment by segment or even specifically for bioprocessing? I think that would be really helpful as we're thinking about how we update our models for the balance of the year. Speaker 500:40:25Yes. I don't think we saw anything meaningful to point out between the regions that are probably too helpful. I think the trends in each region were pretty similar. With maybe the one caveat in Asia, continued weakness, maybe some early signs of stability in China, but less meaningful for us, but continued strength in some of the other sub markets within Asia for us in bio processing, particularly Korea and Southeast Asia. So that might be the only other trend that I might point out. Speaker 500:41:07But I think similar trends between Europe and the Americas. Speaker 1100:41:15And I want to go back to the topic of activity. Again, you've talked about some improvement in activity levels. It totally makes sense how you're managing street expectations. It's really prudent coming off of a tough period from the group over the last several quarters. But in terms of how you're managing the business and keeping in mind internal metrics like corporate goals, are you managing the business with an assumption that the improvement in activity that you've described translates into an increase in the need for product support and ultimately revenue generation in the back half of the year? Speaker 700:41:56Yes. I'd say a couple Speaker 500:41:57of things about that Doug is we're laser focused on executing our long term growth strategy, which means we're investing in innovation, new product introductions, strategic marketing, a lot of investments in our digital platform to position our business for sustained long term growth and to build on our leading position in both of our segments. When I think about the cost transformation initiative that we're driving, it's a multi year effort, quite strategic in nature, linked to the rollout of our new operating segments, which in a very unique way do unlock significant efficiencies. So these come with investments in capability that strengthen the footprint, investments in technology that allow us to do things a bit more efficiently. So we'll benefit from the savings associated with that in the near term, which is helpful in an environment of maybe a little bit muted volumes. But there's nothing that we're doing here that prevents us from growing the business as it returns. Speaker 500:43:21And when I think about our incentive systems, certainly there's a bias for delivering side in both our in year as well as our equity plans. Speaker 1100:43:34Super helpful. Thank you again. Operator00:43:41Our next question comes from Rachel Van Stahl with JPMorgan. Please go ahead. Speaker 1200:43:48Great. Good morning and thanks for taking the questions. So I want to follow-up on Vijay's question around bioprocessing. Great to hear that sequential growth on orders. Can you actually give us what was the number in terms of sequential growth for this quarter and for last quarter since you said it accelerated in terms of the velocity? Speaker 1200:44:04And can you break out how orders trended by customer type across pharma, biotechs and CDMOs? And then specifically on the full year guide, we heard you reiterate the mid single digit declines on bioscience production, but can you just confirm, are you still expecting mid single digit declines for the full year on bioprocessing as well? Speaker 500:44:22Yes, a lot to unpack there. You may have to redirect me here if I don't respond to each of your questions there, Rachel. But to your first one about the bioprocessing order book, we haven't quantified a book to bill or gotten too specific about this. I'm not sure we're going to be granular enough to satisfy your needs here. But we'll just reiterate, again, 2 straight quarters of sequential improvement. Speaker 500:44:49The rate of that improvement is increasing. In terms of comparative to other numbers that you've seen out there as well as order book. And I'd characterize our order book as best in class based on the data points that we've seen that are out there. As I think about the full year, the bioprocessing did perform a bit better in the quarter as Brent indicated. But on the second quarter, we would see bioprocessing moving from kind of a low teens decline in Q1 to something in that mid to high single digit declines for the Q2. Speaker 500:45:44And as you suggest on a full year basis, I think the right way to model it at this stage would still be a mid single digit decline overall, which implies another sequential improvement in Q3 and ultimately a final improvement there in Q4, primarily driven by just the weaker comparables. As we've said before, our guidance assumes relatively similar absolute levels of revenue in each period. And so the step up in growth rate there is really just driven off of the prior year comparables. Speaker 1200:46:24Great. Thanks. And then appreciate we're only a few weeks into the quarter here, but can you talk to us about the trends that you've been seeing in April so far across lab solutions and then bioscience production and bioprocessing specifically as well? So has there been anything specifically to call out that shifted relative to exit rates from 1Q in March as well? Speaker 500:46:46Yes. I'd say we're obviously early in the quarter here, not quite through April yet, but certainly do follow the business real time. And the trends that we're seeing in April, I think are consistent with our commentary today and certainly reflected in our perspective on how we see Q2 trending, which again when I look at the first half based on what we did in Q1 with what we said we anticipate doing in Q2, we're right in line with where we started the year, which is expectation of roughly 49% of our revenues in the first half, 51% our revenues in the second half. And so I think what we're seeing here in April certainly is consistent with the guidance that we've provided you here today. Operator00:47:39Thank you. The next question comes from Tejas Sawant with Morgan Stanley. Please go ahead. Speaker 1300:47:51Hey, guys. Good morning. Maybe I'll start on the CDMO side, Michael. I think you sort of alluded to what you see in that end market in China and the fallout from the Bio Secure Act and so on. But with the prospect of the degree of consolidation here or M and A rather in the U. Speaker 1300:48:12S, does that impact your near term visibility at all in terms of your relationship there with Catalent specifically? Is there a possibility that after change of ownership there, the terms of that contract might need to be renegotiated? Speaker 500:48:28Yes. So if you're speaking momentum we have there. And not maybe unsurprising to you just given how pervasive we are in serving this market across the board. Clearly, we'd have a relationship with their potential acquirer here. And so to the extent that gets done, we look forward to continuing the collaboration with Novo. Speaker 500:49:02When we think about our bioprocessing business, one of the things I really like about it, of course, is that our materials, our ingredients, our buffers, our chromatography resins, our single use solutions are specked into the process and are part of the regulatory filing. So it's one of the things that makes it rather resilient and quite sticky. And there's certainly nothing from a contractual perspective that has us concerned there. To expand a little bit and take it beyond just Catalent though, we don't have much customer concentration in this business. And in fact, it's quite a diversified platform. Speaker 500:49:44So we're going to be well exposed across, of course, the OEMs, but also the playing field there for all the CMOs around the world. And so we're well positioned to support the strategies of our the OEMs and the innovation cycles that are in play here. And as it relates to BioSecure and China, it's a little bit of a balloon, any impact that some of those partners may see negatively presumably will show up somewhere else in the network that will be able to help our customers through. So I really like our positioning and setup here. Speaker 1300:50:22Got it. That's great to hear. And then a quick follow-up on the geopolitical side of things outside of China. And it's more of a medium term question really. What are you hearing in terms of governments in Europe starting to push for a greater degree of self reliance when it comes to their own defense expenditures? Speaker 1300:50:42They want to have a layer of insulation in place relative to the U. S. Election outcomes, etcetera. Is there a risk here in your mind that research budgets there could get crowded out, not so much in 2024, like I said, but more in 2025 and beyond? Speaker 500:50:58Undoubtedly, there's a higher degree of geopolitical tensions around the world and we follow that closely to see how it impacts the business. But I think specific to your question, at the end of the day, it's our strong conviction that good science gets funded and we're quite encouraged by the pipelines and the new modalities and the research that's underway. These pipelines are as full as they've ever been. Things are accelerating through particularly on cell and gene therapy. Again, I mentioned I think there's been 3 approvals year to date. Speaker 500:51:37I think there was a 4th one that came through even this morning. And so you see the rate of those things starting to pick up. So I think history has shown and I don't think we've seen anything here in the near term environment that would cause us to waiver on that, that this promising good science that's in flight here is going to get the funding it needs to progress. Speaker 1300:52:01Thanks, Michael. Appreciate the time. Operator00:52:08The next question comes from Josh Boardman with Cleveland Research. Please go ahead. Speaker 300:52:14Good morning. Thanks for taking my questions. A couple for you. First, Brent or Michael, wondering if you could comment on how you think visibility in the 90 days. Are you seeing any improvement in regards to the team's ability to forecast sales here in the near or medium term? Speaker 300:52:32And then along those lines, can you talk about how or if you're seeing bulk orders come back into the business and how that impacts your ability to forecast? Speaker 500:52:46Yes. Thanks, Josh. Good to hear from you. A couple of things I would say about visibility. I think one of the remarks I may have made in my prepared remarks was just some of the early returns we're getting from our new structure to the business. Speaker 500:53:03It's easier to think about these businesses from a more simplified and then a more logical, in my opinion, structure to the business. It's easier to think about these businesses from a customer needs, research or production environment and it certainly aligns better with how our customers think about it as opposed to our historical approach from a geographic standpoint. So our operating reviews have become a lot more streamlined and a lot more straightforward, which from our perspective is certainly a helpful improvement. It's a relatively short order cycle business as I commented earlier. And so I wouldn't say we've seen really any meaningful change in that regard over the last 90 days or so. Speaker 500:53:44Our supply chains have largely normalized in both segments. So we're back to pretty healthy levels of service in our lab segment, which means we can satisfy most orders in a day or 2. On the production side, we're 2 to 3 months out, which is kind of pre COVID levels of performance there. So I'd say the visibility is similar. Now, of course, with an accelerating order book and improved building order book here that gives us a little bit more forward visibility on the production side of the business and certainly more confidence in underwriting the outlooks that we have here, which I think is encouraging. Speaker 500:54:28Your second question there around how we've seen a return for bulk orders. In our business model, if I think about the ingredients or buffers, excipients, our customers don't typically have the ability to store just elevated levels of product. And so they tend to sync their orders with their production campaigns. And consistent with kind of the destocking trends that we've seen that was more prevalent on single use than it was on the process ingredients for those reasons. And so I would say the size of the orders has been pretty consistent on the process ingredient side. Speaker 500:55:12And then on the single use side, I don't know, I'd say that we've seen a change in order size. We're certainly starting to see with the orders return, the positive indications of destocking presumably coming to an end here in the near term and good underlying levels of activity. Speaker 300:55:36Got it. Thanks, Michael. And then, wondering if you could talk a bit more about the pricing and share environment. You commented on contract wins. Any more context you could provide there? Speaker 300:55:46And then do you think you're seeing more account churn than normal this year? So does that pose any risk to pricing as the year plays out? Or would you see it more as a potential opportunity for share and maybe top line outperformance? Speaker 500:56:03Maybe take those in reverse order, maybe talking first about your questions on pricing, then I'll talk about share. On the pricing side, I would say the team has delivered another solid year of execution on this and executing on that playbook. We expect kind of 1 to 2 points of contribution coming from price that's primarily offsetting the COGS inflation that we are seeing. So pretty close to historical levels of contribution, I would say, coming from price. And I think the teams did a nice job putting that through and not a lot of noise around that at this stage. Speaker 500:56:47We'll see a little bit of step up in revenue in the Q2 as those price increases. We get the full phasing of those in the quarter. So pretty pleased about where we're at from a pricing standpoint and certainly one of the favorable drivers of margin that we do see. Share is a great story for us and certainly excited to talk about that. On the production side, I think we've got a long standing track record particularly in our bio materials and bioprocessing business of share growth. Speaker 500:57:16You typically see us outperforming the broader market on bioprocessing 300 basis points to 400 basis points. And again, even with the declines we saw in the quarter, I think that performance is as good as you're going to see and certainly again best in class. And even if you were to adjust for maybe our more modest exposure to China, I think that's still a true statement. On the lab side, we've talked a lot about our strong focus in the academia world. We continue to see nice growth there and nice penetration and a lot of new customer wins there, a lot of important contract renewals. Speaker 500:57:57That's an end market or a customer segment that historically has been a little bit more open to churn. I'm not sure we're seeing it any differently now. Maybe we're playing it a bit more aggressively now. But just with their more fixed budget environment and less sensitivity to maybe some of the high regulatory environment that a biopharma customer might have, that is an area that we think that we can continue to be successful with. So again, another great quarter here of we think share expansion in both of our segments. Speaker 300:58:39Got it. Thank you, Michael. Appreciate all the color. Operator00:58:46We have time for one final question today. And so our next question comes from the line of Patrick Donnelly with Citi. Please go ahead. Speaker 1000:58:56Hey, guys. Thanks for getting me in here. Michael, I know in the last call you talked a little bit about some of the margin pacing and even the exit rate potential this year. I guess with the bioprocessing order improvement, obviously, nice margin flow through on that, the cost savings plan. Obviously, Brent talked a lot about just the visibility there. Speaker 1000:59:15Can you talk about just the confidence on that margin exit rate and how you are viewing things on that front given the current trends? Speaker 500:59:23Yes, it's a really good question, Patrick. We've reaffirmed our full year guidance today, which I think does a couple of things for us. 1, it shows our confidence in the plan that we have in place. But with the margin outperformance that we drove in Q1, of course, that has the effect then of derisking the margin ramp that was necessary to hit the full year margin numbers. So I like that. Speaker 500:59:54Certainly, it's early in the year. Brent talked a bit today about our cost transformation initiative that seems to be ahead of plan. Still a lot of things to get done on that front this year, but we're focused on executing those and perhaps there'll be some upside as we get further into the year. But I think it's at this stage of where we're at in the calendar, prudent to kind of bank the outperformance in Q1, continue to drive hard on all the initiatives that we have in flight here and we'll keep you updated as we move through the quarter. But I think the read for me on this is just a bit of derisking here on being able to deliver that margin target for the full year. Speaker 1001:00:42That's helpful. And just a very quick one. I know some time is tight. But Brent, just on the debt pay down visibility, leverage exit rate, when you guys start to think about capital deployment getting back in the mix there? Thank you, guys. Speaker 301:00:56Yes, sure. Thanks, Patrick. Look, we continue to generate cash very well. We're holding our pre transformation cost cash flow guidance for the year. Just you do the math on that, it would certainly absent a meaningful increase in EBITDA will certainly be within 2025. Speaker 301:01:15I mean, we're absolutely committed to getting to adjusted net leverage of below 3 times. We're certainly doing what we can to accelerate that, but say we'll keep posting you every quarter and we're going to keep diligently grinding down the debt balance. Operator01:01:35Those are all the questions we have time for today. And so this concludes our question and answer session. I would now like to turn the call back over to Michael for any concluding remarks. Speaker 501:01:46Yes. Thank you. Comments today, we're encouraged by the at least You can tell from our comments today, we're encouraged by the leading indicators that we're seeing, particularly in the improving order book in bioprocessing. We're out of the gate strong with our cost transformation initiative. We're able to accelerate some savings into the Q1 here and I'm pleased with our progress here. Speaker 501:02:18So thank you all for joining us today. Certainly look forward to updating you when we meet next. Until then, be well everyone. Operator01:02:28Thank you everyone for joining us today. 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There are 14 speakers on the call. Operator00:00:00Good morning. My name is Emily, and I'll be your conference operator today. At this time, I would like to welcome everyone to Avantor's First Quarter 20 24 Earnings Results Conference Call. After the presentation, there will be the opportunity for you to ask any I will now turn the call over to Christina Jones, Vice President of Investor Relations. Ms. Operator00:00:24Jones, you may begin the conference. Speaker 100:00:26Good morning. Thank you for joining us. Our speakers today are Michael Stubblefield, President and Chief Executive Officer and Bren Jones, Executive Vice President and Chief Financial Officer. The press release and a presentation accompanying this call are available on our Investor Relations website at ir.avantorsciences.com. A replay of this webcast will also be made available on our website after the call. Speaker 100:00:58Following our prepared remarks, we will open the line for questions. During this call, we will be making forward looking statements within the meaning of the U. S. Federal securities laws, including statements regarding events or developments that we believe or anticipate may occur in the future. These forward looking statements are subject to a number of risks and uncertainties, including those set forth in our SEC filings. Speaker 100:01:26Actual results might differ materially from any forward looking statements we make today. These forward looking statements speak only as of the date that they are made. We do not assume any obligation to update these forward looking statements as a result of new information, future events or other developments. This call will include a discussion of non GAAP measures. A reconciliation of these non GAAP measures can be found in the press release and in the supplemental disclosure package on our Investor Relations website. Speaker 100:02:00As a reminder, on January 1, 2024, we transitioned from our former regional segment structure to 2 global operating segments, Laboratory Solutions and Bioscience Production. Our Q1 2024 results are presented on this basis. With that, I will now turn the call over to Michael. Speaker 200:02:24Thank you, CJ, and good morning, everyone. I appreciate you joining us today. I'm starting on Slide 3. The year is off to a good start as we delivered 1st quarter revenue in line with our guidance with reported revenue of $1,680,000,000 and organic growth of minus 6.3 percent. As anticipated, market conditions remain similar to the 4th quarter. Speaker 200:02:49Our team continues to execute well as evidenced by our margin and profitability outperformance with adjusted EBITDA margin of 16.8% and adjusted EPS of $0.22 As Brent will outline in his section, our margins were driven by pricing, favorable product mix, disciplined cost management and accelerated realization of savings from our multi year cost transformation initiative. We also generated $107,000,000 of free cash flow in the quarter. Consistent with our current capital allocation priorities, we paid down approximately $170,000,000 of debt and continue to target an adjusted net leverage ratio below 3 times. As CJ noted, our new operating model became effective in January. Our new business segments enhance our focus on customers' needs in the lab and production environments, position us for accelerated long term growth and unlock significant operating efficiencies. Speaker 200:03:46We are early in our journey, but are out of the gate strong and are already realizing benefits from the new model. During the Q1, we aligned our organization with the new business segments and initiated several work streams to optimize the Avantor customer experience. Our commercial intensity and the relevance of our workflow solutions resulted in multiple competitive wins and contract renewals with biopharma, healthcare and education and government customers. As part of our innovation strategy, we enhanced our offerings for cell engineering, gene therapy and synthetic biology applications through supplier partnerships and proprietary innovation. We are seeing strong customer response to recent proprietary new product introductions, including our viral inactivation solutions launched earlier this year and our integrated mixing systems and fluid handling assemblies, which are delivering critical efficiency and quality improvements to our bioprocessing customers. Speaker 200:04:45We also advanced our multi year cost transformation initiative, including footprint optimization, organizational efficiency, go to market and procurement savings. Our disciplined execution enabled us to accelerate the realization of some savings into the Q1, contributing to our margin and profitability outperformance. We continue to be encouraged by the positive trends we are seeing in our end markets. In laboratory solutions, biotech funding is improving and our large pharma customers are engaging with us on new projects that are driving an increase in our commercial opportunity funnel. Core diagnostic testing has returned to growth and QA QC workflows in the applied markets have been relatively stable. Speaker 200:05:31Additionally, internal and external surveys suggest that inventory health continues to improve. Collectively, these factors resulted in a sequential increase in sales of our consumables and chemicals offerings, both key drivers of our long term growth. In bioscience production, the bioprocessing end market remains healthy with a robust pipeline of new therapies, a favorable regulatory landscape including 3 new cell and gene therapy approvals in the quarter and strong patient demand. Importantly, we saw another quarter of sequential improvement in our bioprocessing order rate. Within healthcare, medical implant procedure rates continue to be positive and overall demand within the semiconductor end market has rebounded from the lows we experienced in 2023. Speaker 200:06:19Consistent with our in line revenue performance in the quarter, these encouraging market signals have not yet translated into an inflection in aggregate sales levels as pockets of inventory destocking and cautious customer spending, notably in equipment and instrumentation continue to impact demand. We believe our current approach to guidance, which assumes a continuation of current market conditions is appropriate and we are reaffirming our full year outlook. Should a meaningful market recovery take place within the year, that would present upside to our guidance. Before I turn it over to Brent, I'd like to share a few takeaways from the quarter, which show that our model is working. 1st, momentum in our consumables portfolio, representing the vast majority of our revenue, largely offset industry wide weakness in capital driven equipment and instrumentation sales and translated to outperformance in margins and EPS. Speaker 200:07:142nd, our BAW processing offerings are strategically positioned to benefit from attractive end market fundamentals and we outperformed our bioprocessing guidance and realized another sequential step up in bioprocessing orders. Finally, we are taking action to strengthen performance and drive productivity. We made meaningful progress in transforming our operating model and we are ahead of plan on our cost transformation initiative. With that, I'll now turn it over to Brent to walk you through our Q1 results in more detail. Speaker 300:07:46Thank you, Michael, and good morning, everyone. I'm starting with the numbers on Slide 4. Reported revenue was $1,680,000,000 for the quarter, declining 6.3% on an organic basis. In our Laboratory Solutions segment, sales trends were generally similar to the 4th quarter levels. We are seeing nice momentum in consumables and chemicals offset by softer than expected demand for equipment and instrumentation. Speaker 300:08:12Our Bioscience Production segment performed modestly ahead of expectations driven by upside in bioprocessing and biomaterials. Adjusted gross profit for the quarter was $572,000,000 and adjusted gross margin was 34%. Year over year, our adjusted gross profit was impacted by lower sales volume and unfavorable product mix, partially offset by productivity. Adjusted gross margin improved nicely on a sequential basis. This was largely due to pricing and the positive mix impact from strength in higher margin consumables and weakness in lower margin equipment and instrumentation. Speaker 300:08:53Adjusted EBITDA was $283,000,000 and adjusted EBITDA margin was 16.8%. Adjusted operating income was $258,000,000 at a 15.4 percent margin. Year over year, our adjusted EBITDA and adjusted operating income performance were impacted by lower sales volumes and unfavorable mix. While adjusted EBITDA and adjusted operating income were down sequentially, primarily from the reset of incentive compensation, our margins were well above our expectations. This outperformance was driven by better than expected mix and the accelerated impact of certain cost transformation initiatives up and down the P and L. Speaker 300:09:38Net interest expense and adjusted tax expense were in line with our expectations, resulting in adjusted earnings per share above expectations at $0.22 for the quarter. Moving to free cash flow, we generated $107,000,000 in the quarter. Our free cash flow performance was impacted by costs associated with our cost transformation initiative. Our adjusted net leverage ended the quarter at 4 times adjusted EBITDA. The slight uptick in leverage was driven by a reduction in our trailing 12 months adjusted EBITDA. Speaker 300:10:13As Michael noted, we remain focused on deleveraging and pay down approximately $170,000,000 of debt in the quarter. In April, we favorably repriced about $770,000,000 of term loans, reflecting a supportive financing market and strong demand for our debt. Slide 5 outlines our segment performance. Launching our 2 new segments has been a critical strategic move to sharpen our focus on accelerating growth and streamlining organizational accountability. It also has the benefit of unlocking significant savings. Speaker 300:10:51In laboratory solutions, which represents roughly 2 thirds of our revenue, we provide an industry leading platform of products, services and digital solutions to support our customers' research, diagnostic and QC workflows. Laboratory Solutions revenue was $1,160,000,000 for the quarter, declining approximately 4.5% versus prior year on an organic basis. Our consumables and chemicals, both proprietary and third party, showed sequential growth performing better than our expectations. However, momentum in these categories was offset by lower equipment and instrumentation sales in each of our end markets. Adjusted operating income for laboratory solutions was 100 and $48,000,000 for the quarter, representing a 12.8 percent margin. Speaker 300:11:45Year over year adjusted operating income decline was driven by negative sales volume. Sequentially, we saw favorable mix due to strength in higher margin consumables and chemicals and weakness in lower margin equipment and instrumentation. However, despite the mix impacts on gross profit, adjusted operating income declined due to the impact of our annual incentive compensation reset. This expense increase was partially offset by savings from our cost transformation initiative. Our Bioscience Production segment represents about 1 third of our revenue and over 45% of our enterprise profitability. Speaker 300:12:25This business supports customers' production platforms by providing high purity process ingredients and single use solutions for bioprocessing, ultra high purity silicone formulations for medical implants and custom solutions for semiconductor and advanced technology applications. Bioscience production revenue was $523,000,000 representing an organic decline of approximately 10%, slightly ahead of our expectations for the quarter. Bioprocessing was down low teens on an organic basis versus our expectations of down mid teens. Adjusted operating income for bioscience production was $127,000,000 for the quarter, representing a 24.3 percent margin. Year over year adjusted operating income declined as a result of lower sales volume. Speaker 300:13:19On a sequential basis, despite revenue performance exceeding our expectations and solid mix, adjusted operating income declined modestly driven by the expense side. Like laboratory solutions, this was largely due to our incentive compensation reset. However, these expense accruals were partially offset by savings from our cost transformation initiative. Altogether, a solid quarter in both segments. Moving to the next slide. Speaker 300:13:50Slide 6 shows our full year 2024 guidance. As referenced throughout the call today, we see encouraging signs in our end markets. However, it is still early in the year and the operating environment remains dynamic. As Michael indicated, we believe it is prudent to base our guidance on a continuation of current market conditions and we are reaffirming our full year guidance as outlined last quarter. This includes organic revenue growth of negative 2% to +1%, adjusted EBITDA margin of 17.4% to 17.9% and adjusted EPS of $0.96 to $1.04 We also expect free cash flow performance of $600,000,000 to $650,000,000 excluding any cash costs associated with our cost transformation initiative. Speaker 300:14:46On a segment basis, we expect low single digit growth in laboratory solutions and a mid single digit decline in bioscience production. A couple of comments on phasing. As laid out at the beginning of the year, we expect to generate 49% of our full year revenue in the first half and 51% in the second half. This leads to Q2 organic revenue growth of approximately negative 3.5% to negative 1.5%. The modest sequential increase in reported revenue dollars as we progress through the year is driven by pricing phasing, lot of seasonality, timing of known orders and nominal billing day adjustments. Speaker 300:15:31In terms of profitability, we expect our Q2 gross margin per seige to be similar to Q1. Adjusted EBITDA margin should improve by about 25 to 50 basis points sequentially, driven by the impact of our cost transformation initiative. Our ability to accelerate our transformation savings into the Q1 flattens the margin ramp needed to achieve our full year plan. We are executing well against the transformation plan evidenced by the nice pull forward of savings into Q1. We are solidly on track to achieve at least $75,000,000 of in year savings in 2024. Speaker 300:16:10With that, I will turn the call back to Michael. Thank you, Brent. Speaker 200:16:15With our new operating model in place, we're well positioned to realize accelerated long term growth and unlock significant operating efficiencies. We are seeing the benefits of our new business segments in driving commercial momentum with our research and production customers as well as enhancing our operational rigor and forecasting. I am pleased with the progress we have made on our multi year cost transformation initiative. We are ahead of plan and are already seeing the impact in our cost structure and margins. As the market recovers, we will be well positioned to enhance the conversion of top line growth to improve bottom line profitability. Speaker 200:16:53I'd like to close by thanking our Avantor associates for their steadfast dedication to serving our customers and to creating a better healthier world. Their contributions enabled us to make meaningful progress on our business transformation and deliver on our operating plan. I will now turn it over to the operator to begin the question and answer portion of our call. Operator00:17:36Our first question today comes from the line of Michael Ryskin with Bank of America. Please go ahead. Speaker 400:17:44Great. Thanks for taking the question guys. Michael, I want to start with one for you if I could. You talked throughout the call about consistent market conditions, no real change there. But you also did call out some encouraging market signals that just haven't translated to sales yet. Speaker 400:17:58When we think about Avantor, we typically think of it as being a relatively fast order cycle. So could you just help us understand if the market signals do start to flow through, if the market conditions do improve, sort of like what's the lag between when you start seeing that and when it shows up in the revenues? And obviously, there could be differences in different end markets, maybe touch on semis, bioprocessing, anything else? Thanks. Speaker 500:18:21Yes. Good morning, Michael. Thanks for the question. Yes, you're right. We are, as we said in the script, recently encouraged by what we're seeing in the marketplace. Speaker 500:18:31A lot of the leading indicators, whether it's funding, improvements in order books particularly in bioprocessing, customer activity, building up pipelines, approvals of new drugs. I think there was even another approval this morning coming out of the pipeline. So a lot to like about the setup for our end markets. We do have a relatively short order cycle business model as we've talked about previously within our lab solutions segment. That's more of a book and ship type of business. Speaker 500:19:06So we kind of take orders real time and would anticipate shipping those typically within a 24 to 48 hour period. So as these signals translate into increase in orders and ultimately into revenue, we'll see that pretty much real time. Bioscience Production segment tends to be driven by a little bit longer lead times that have normalized post the pandemic. We're on average probably 2 to 3 months out in terms of being able to satisfy a customer order there. And so we'll see that inside of a quarter if at most maybe with a 1 quarter lag. Speaker 400:19:51I was on mute. Thanks. That's really helpful. And then quick follow-up. You did call out in Lab Solutions a little bit of pressure in equipment instrumentation, realize it's a very small part of your overall mix, but anything specific you can touch on there, whether it's big pharma or biotech that's still a little bit lagging? Speaker 400:20:09And just there, you would have a little bit better visibility. So do you think that's just a timing thing to start the year? Or is that budget still being constrained? Thanks. Speaker 500:20:22So I'd probably highlight a couple of things here, Michael. Firstly, as you suggest, E and I for us is a relatively modest part of the business, about 15% of our overall revenue, a little bit more pronounced in our lab solutions segment. We are seeing kind of industry wide pressures for purchase of equipment and instrument driven by project delays and extended times to get projects approved and a little bit more cautious approach to just getting capital related purchasing items approved real time here. It was a slow start to the year and that which isn't unusual coming out of year end where folks will typically try to buy ahead for some of their demand. But unlike a normal year where you'd see that kind of pick up as you move through the quarter, we didn't really see that acceleration. Speaker 500:21:16And so unlike the momentum that we saw in our consumables portfolio where both in consumables and chemicals both in both of our segments where we saw a nice acceleration coming from Q4 to Q1, we didn't really see that in the E and I piece. I'd probably say it's probably most notably in biopharma is where we see it, but we probably look at it across all of our end markets at some level. Speaker 400:21:47Great. Thanks so much. Operator00:21:53The next question comes from Dan Leonard with UBS. Please go ahead. Speaker 600:21:59Thank you. I have a follow-up on that last question. Michael, possible you could frame the magnitude of the decline in E and I in the quarter? And I ask because it's not a big part of your business, but it seems to have fully offset the outperformance in recurring within your lab business specifically? Speaker 700:22:22Yes. I guess I'd say probably a couple Speaker 500:22:23of things, to maybe lay some tracks for you on that. If I look at our Bioscience Production segment as an example, you saw the modest outperformance that we drove there reflecting a bit of momentum in bioprocessing in certain our biomaterials business, our electronics business has recovered from the lows that we experienced in 2023. But again, was somewhat modest, but encouraging nonetheless, but nothing that we would consider to be an inflection point. And we have relatively modest equipments and instrumentation exposure in that segment. Now if I look at the Lab Solutions segment by comparison, we have a bit more exposure there. Speaker 500:23:07It's probably on the order of 20% of the revenues or thereabouts would be in the equipment and instrument space. So reasonably meaningful. We did see similar upside to our consumables and chemicals growth is what we saw in our production segment that was basically fully offset by the sequential weakness in E and I. So although we are a consumables driven business, roughly 15% of our overall sales are linked to equipment and instrumentation. So weakness certainly does get reflected. Speaker 500:23:44Fortunately, with the consumables portfolio and the higher margins that are associated with that part of the portfolio, you see the impact on mix. And as I highlighted in my script, we really focus here on the consumables business and I'm quite encouraged by, A, not only the momentum on the top line, but the flow through of that to margins on the bottom line and you see that helping with some of the outperformance on the margin line. Speaker 600:24:14Appreciate that. And then as a follow-up, you mentioned that bioprocessing is doing a bit better, but not yet in inflection. I was hoping you could elaborate on the performance of any of the leading indicator product categories within bioprocessing and what they're telling you? Thank you. Speaker 500:24:33We are quite encouraged to see a second straight quarter here of sequential improvement in bioprocessing order book trends. And maybe adding to our encouragement here is we saw the pace of step up here accelerate in Q1 even a bit more than what we saw in Q4 and it's widespread. We're seeing it both in the Process Ingredients, excipients part of our business as well as encouraging in our single use platform. We've talked over recent quarters a fair bit about the pickup in engineering activity, which is certainly a story will play a nice leading indicator for our single use business, hadn't yet translated into an order book. It feels like we're starting to see that start to translate quite nicely. Speaker 500:25:25And it's with large pharma, it's with CDMOs and so we like how broad the pickup appears to be at the moment. But to your point, and consistent with what we've said and how we've guided, we've not yet realized that pickup in the order book in a meaningful change in our sales trends. And so our guidance reflects a continuation of current conditions. But certainly, a couple of straight quarters here where we're pretty encouraged. Speaker 800:26:00Thanks, Michael. Operator00:26:06The next question comes from Dan Brennan with TD Cowen. Please go ahead. Speaker 700:26:14Great. Thank you. Thanks for the questions. Michael, maybe just on the lab solutions business since that came in a bit weaker here. Just can you discuss kind of how the quarter played out? Speaker 700:26:24Any versus expectations kind of what trended a little bit lighter than what you expected and what gives you confidence in kind of the full year there? Speaker 500:26:34Yes. So I think we called for roughly low single digit decline in the quarter. It came out maybe a point or so weaker than that, really all on the back of the E and I trends that we've discussed here on the call and in the early questions. The 80% of that segment that's consumables, chemical services actually performed better than our expectations. And we're starting to see some nice acceleration there, which I think is reflective of the destocking trends that we're seeing and the improvement of inventory health as well as just a good indicator of funding and activity levels, engagement with our customers across the board. Speaker 500:27:22So the 2 largely offset one another. But yes, the weakness there was really driven by continued cautious approach to capital purchase spending there in the equipment and instrument category. Speaker 700:27:42And then maybe a follow-up for Brent, just in terms of the nice progress on the cost saves and the nice margins in the quarter, you guys are maintaining the full year guide. Just walk through a little bit of like what drove the upside in the quarter there? And did that give you potential upside bias to how you think the full year plays out? Speaker 300:28:02Yes, absolutely. Thanks for the question. Obviously, the cost transformation has been a huge focus for us. And Michael noted our 4 pillars organizational efficiency, footprint optimization, go to market and procurement. Unsurprisingly given that they're sort of shorter cycle and actions, we outperformed on the organizational efficiency and the procurement side there. Speaker 300:28:26A lot of this is frankly unlocked by the new segment structure, which really allows us to get the efficiencies of the new model and frankly that also drove to the procurement piece of it. In terms of look on the full year there, let's say, we are gratified with the strong start. We worked really hard at that and we're going to continue, But it's early in the year and there are a lot of moving pieces. So I think let's hold it $75,000,000 is a good assumption for the year. But if we get acceleration, certainly the next time we talk to you, we'll let you know. Operator00:29:08The next question comes from Luke Sergott with Barclays. Please go ahead. Speaker 900:29:14Great. Thanks, guys. Just wanted to follow-up on that last question. And so when we're thinking about the pacing of the cost out structure across the margins for the rest of the year, can you help give us a little help on the modeling side and then by segment? And then the blend there between the gross margin and operating and SG and A? Speaker 300:29:39Look, I think that's 7 questions, but I'll do my best. So, yes, so on the progression there, again, nice outperformance and transformation in Q1. We'll see a meaningful uptick in transformation saves in Q2 and then that will increase somewhat ratably in Q3 and Q4 unsurprisingly just due to the timing of actions particularly on org efficiency but as well as procurement and the others. And then we do starting in Q2 have merit coming in so that's not a material headwind against it. So you won't see a dramatic change in the SG and A line in Q2. Speaker 300:30:20You will see some goodness with additional actions then in the back half of the year. We're not breaking the transformation down really by segment here. It's unlocked by that, but we're not going to make external comments there. But then it just that will lead to kind of as you get that ratable improvement there as well as as you get that ratable improvement there that will just nicely lift EBITDA margin there When you do the math on keeping the full year guide and we really expect gross margins to be pretty consistent based on what we're seeing. So you manage those together, I would think of that in a pretty linear basis honestly for how the year lays out. Speaker 900:31:01All right. That's helpful. And then so on the BioSecure Act, what are you guys hearing from your customer CDMO customers on that side? And then any exposure to WuXi and that complex that might provide some near term disruption? Or how are you guys thinking about that? Speaker 500:31:22Yes. Look, we obviously are monitoring the developments with that legislation pretty closely. Obviously, the final details are still be determined and we're not in any better position than anybody else probably to try to anticipate where that's going to land and how it ultimately gets implemented. But what I would say is we benefit from a global presence and certainly are well positioned to support our customers through our collaboration model to ensure that we can help them through whatever implications of that act might mean for them. We don't anticipate any particular meaningful at an aggregate level for us. Speaker 500:32:02We don't have a lot of exposure into China specifically. And then on the maybe on the U. S. Side, we're obviously well positioned with both CDMOs as well as the OEMs. And so I think from our perspective, there end up you could end up see some puts and takes between specific accounts. Speaker 500:32:22But as deeply as embedded we are across this space, I think we view us as a solution provider here that you'll be able to help our customers with any implications here. Speaker 900:32:36Great. Thanks. Operator00:32:42The next question comes from the line of Vijay Kumar with Evercore ISI. Please go ahead. Speaker 800:32:50Hi, Michael. Good morning and thanks for taking my question. I guess my first question, Michael, on consumables, I think you said improved sequentially. Can you split that out between bioprocessing and lab solutions? Were consumables up in both segments sequentially? Speaker 800:33:10Was it flattish? I think on the order side for bioprocessing, you did mention sequential growth. Could you quantify that was book to bill perhaps north of 1? Speaker 500:33:24Yes, let me take the two questions there. So consumables are pervasive across both segments as you noted and encouraging that we saw sequential improvement in both segments. We probably have less than, I don't know, 5% of our revenues in our production segment are equipment and instruments. And so that's largely a consumables play for us in that segment. And you saw the modest beat to expectations there and that's all linked to the consumables trends that we did see. Speaker 500:33:56And similarly, although a bit more equipment and instrument exposure on the lab segment, we saw a similar upside from the consumables part of that businesses as well. So again, I think that speaks to just the power of our model. I indicated in my remarks that I think this quarter is actually a really good illustration of how our model is working, where you see the activity levels, inventory health improving, leading to stronger pull through of our core portfolio here, which are bringing the higher margins with it, which led better mix in the quarter and the higher margins as you see. So really like how the model worked in the quarter. Relative to your second question there around the impact of some of the insights there on our bioprocessing order book. Speaker 500:34:53I don't think we've historically discussed a book to bill. We don't find that to be particularly meaningful in our business. But what I can say is, we're now a couple of straight quarters here of sequential improvement. The The acceleration or the improvement that we saw in Q1 was actually even a bit more than what we saw in Q4. So the rate does seem to be picking up some momentum here. Speaker 500:35:19It's broad based, it's across not only our chemicals, process ingredients, excipients categories, but also across our single use platform, which as I said before, we think is maybe the first sign that how the engineering drawing activity we discussed last year is now starting to work its way through the pipeline. We've talked a lot in these forums, Vijay, about our best in class bioprocessing performance, both in terms of absolute revenue performance. And we think with the performance in this quarter, we were as good or better than anybody out there. I think you could probably say the same about the order book trends that we saw. I mean, obviously, we're looking at a lot of the same things that you are. Speaker 500:36:09And I would say we're very pleased with the development of our order book. And I think you could be safe in assuming that it was as good if not better than anything that you've seen reported so far. Speaker 800:36:23That's very helpful, Michael. Maybe one more on instrumentation. Anything on phasing, Michael, in the quarter on instrumentation? Were there any days impact or holiday impact Easter, etcetera? I'm just trying to think instrument was down consistently throughout or anything happened late in the quarter? Speaker 500:36:46The only thing meaningful intra quarter dynamic that I would point out was we got off to a slow start in the year for equipment and instruments, which wasn't such a huge surprise. That's not unusual coming into a new year, folks are had satisfied probably a lot of their near term needs at year end using whatever budget they had, getting budget set for the coming year. What you normally then see though is a pickup and acceleration as you move through the quarter. We didn't see it. It was weak all quarter as it turned out. Speaker 500:37:20So that's probably the only intra quarter dynamic that I would highlight for you. Speaker 1000:37:26Thank you, guys. Operator00:37:31The next question comes from Jack Meehan with Nephron Research. Please go ahead. Speaker 1000:37:39Thank you. Good morning. Michael, could you talk a little bit about the academic end market? It looks like it took a little bit of a step back with the low single digit decline. Heard some it's probably similar to what we're seeing at others. Speaker 1000:37:54But can you just talk about what you're seeing in terms of marketing conditions there? Speaker 500:37:59I'd say a couple of things, Jack. Firstly, you're right. We were down, I think, low single digits in aggregate for that education and government end market. Probably the more important part for us and consistent with what we've been seeing actually over the last several quarters in 2023 was our ongoing share wins and momentum in large academic institutions. And despite that end market overall for education and government being down, our large academic customers were up again in the quarter. Speaker 500:38:42So continued momentum and nice activity levels and that's I highlighted in my prepared remarks, some of the customer wins, renewals and share gains. Certainly, this academic setting, particularly in the U. S. Is a large focus for us and pleased to see yet another quarter of growth. Speaker 1000:39:05Great. And then for Brent, can you just lay out for us on the segment level what the expectations are for organic growth in 2Q? I'm trying to tease out like what's comps versus kind of recovery as we phase through the year? Speaker 300:39:25Yes. As we think about Q2 there, as we noted, we expect lab solutions to be down low single digits and BPS to be down sort of low single digit, mid single digit, which and within that bioprocessing down sort of mid single digit, high single digit. Speaker 1000:39:47Okay. Thank you. Speaker 700:39:50Yes. Operator00:39:54The next question comes from Doug Schenkel with Wolfe Research. Please go ahead. Speaker 1100:40:01Hey, good morning guys and thank you for taking my questions. First, just on geographic trends, anything you can share across the business, capital versus recurring, segment by segment or even specifically for bioprocessing? I think that would be really helpful as we're thinking about how we update our models for the balance of the year. Speaker 500:40:25Yes. I don't think we saw anything meaningful to point out between the regions that are probably too helpful. I think the trends in each region were pretty similar. With maybe the one caveat in Asia, continued weakness, maybe some early signs of stability in China, but less meaningful for us, but continued strength in some of the other sub markets within Asia for us in bio processing, particularly Korea and Southeast Asia. So that might be the only other trend that I might point out. Speaker 500:41:07But I think similar trends between Europe and the Americas. Speaker 1100:41:15And I want to go back to the topic of activity. Again, you've talked about some improvement in activity levels. It totally makes sense how you're managing street expectations. It's really prudent coming off of a tough period from the group over the last several quarters. But in terms of how you're managing the business and keeping in mind internal metrics like corporate goals, are you managing the business with an assumption that the improvement in activity that you've described translates into an increase in the need for product support and ultimately revenue generation in the back half of the year? Speaker 700:41:56Yes. I'd say a couple Speaker 500:41:57of things about that Doug is we're laser focused on executing our long term growth strategy, which means we're investing in innovation, new product introductions, strategic marketing, a lot of investments in our digital platform to position our business for sustained long term growth and to build on our leading position in both of our segments. When I think about the cost transformation initiative that we're driving, it's a multi year effort, quite strategic in nature, linked to the rollout of our new operating segments, which in a very unique way do unlock significant efficiencies. So these come with investments in capability that strengthen the footprint, investments in technology that allow us to do things a bit more efficiently. So we'll benefit from the savings associated with that in the near term, which is helpful in an environment of maybe a little bit muted volumes. But there's nothing that we're doing here that prevents us from growing the business as it returns. Speaker 500:43:21And when I think about our incentive systems, certainly there's a bias for delivering side in both our in year as well as our equity plans. Speaker 1100:43:34Super helpful. Thank you again. Operator00:43:41Our next question comes from Rachel Van Stahl with JPMorgan. Please go ahead. Speaker 1200:43:48Great. Good morning and thanks for taking the questions. So I want to follow-up on Vijay's question around bioprocessing. Great to hear that sequential growth on orders. Can you actually give us what was the number in terms of sequential growth for this quarter and for last quarter since you said it accelerated in terms of the velocity? Speaker 1200:44:04And can you break out how orders trended by customer type across pharma, biotechs and CDMOs? And then specifically on the full year guide, we heard you reiterate the mid single digit declines on bioscience production, but can you just confirm, are you still expecting mid single digit declines for the full year on bioprocessing as well? Speaker 500:44:22Yes, a lot to unpack there. You may have to redirect me here if I don't respond to each of your questions there, Rachel. But to your first one about the bioprocessing order book, we haven't quantified a book to bill or gotten too specific about this. I'm not sure we're going to be granular enough to satisfy your needs here. But we'll just reiterate, again, 2 straight quarters of sequential improvement. Speaker 500:44:49The rate of that improvement is increasing. In terms of comparative to other numbers that you've seen out there as well as order book. And I'd characterize our order book as best in class based on the data points that we've seen that are out there. As I think about the full year, the bioprocessing did perform a bit better in the quarter as Brent indicated. But on the second quarter, we would see bioprocessing moving from kind of a low teens decline in Q1 to something in that mid to high single digit declines for the Q2. Speaker 500:45:44And as you suggest on a full year basis, I think the right way to model it at this stage would still be a mid single digit decline overall, which implies another sequential improvement in Q3 and ultimately a final improvement there in Q4, primarily driven by just the weaker comparables. As we've said before, our guidance assumes relatively similar absolute levels of revenue in each period. And so the step up in growth rate there is really just driven off of the prior year comparables. Speaker 1200:46:24Great. Thanks. And then appreciate we're only a few weeks into the quarter here, but can you talk to us about the trends that you've been seeing in April so far across lab solutions and then bioscience production and bioprocessing specifically as well? So has there been anything specifically to call out that shifted relative to exit rates from 1Q in March as well? Speaker 500:46:46Yes. I'd say we're obviously early in the quarter here, not quite through April yet, but certainly do follow the business real time. And the trends that we're seeing in April, I think are consistent with our commentary today and certainly reflected in our perspective on how we see Q2 trending, which again when I look at the first half based on what we did in Q1 with what we said we anticipate doing in Q2, we're right in line with where we started the year, which is expectation of roughly 49% of our revenues in the first half, 51% our revenues in the second half. And so I think what we're seeing here in April certainly is consistent with the guidance that we've provided you here today. Operator00:47:39Thank you. The next question comes from Tejas Sawant with Morgan Stanley. Please go ahead. Speaker 1300:47:51Hey, guys. Good morning. Maybe I'll start on the CDMO side, Michael. I think you sort of alluded to what you see in that end market in China and the fallout from the Bio Secure Act and so on. But with the prospect of the degree of consolidation here or M and A rather in the U. Speaker 1300:48:12S, does that impact your near term visibility at all in terms of your relationship there with Catalent specifically? Is there a possibility that after change of ownership there, the terms of that contract might need to be renegotiated? Speaker 500:48:28Yes. So if you're speaking momentum we have there. And not maybe unsurprising to you just given how pervasive we are in serving this market across the board. Clearly, we'd have a relationship with their potential acquirer here. And so to the extent that gets done, we look forward to continuing the collaboration with Novo. Speaker 500:49:02When we think about our bioprocessing business, one of the things I really like about it, of course, is that our materials, our ingredients, our buffers, our chromatography resins, our single use solutions are specked into the process and are part of the regulatory filing. So it's one of the things that makes it rather resilient and quite sticky. And there's certainly nothing from a contractual perspective that has us concerned there. To expand a little bit and take it beyond just Catalent though, we don't have much customer concentration in this business. And in fact, it's quite a diversified platform. Speaker 500:49:44So we're going to be well exposed across, of course, the OEMs, but also the playing field there for all the CMOs around the world. And so we're well positioned to support the strategies of our the OEMs and the innovation cycles that are in play here. And as it relates to BioSecure and China, it's a little bit of a balloon, any impact that some of those partners may see negatively presumably will show up somewhere else in the network that will be able to help our customers through. So I really like our positioning and setup here. Speaker 1300:50:22Got it. That's great to hear. And then a quick follow-up on the geopolitical side of things outside of China. And it's more of a medium term question really. What are you hearing in terms of governments in Europe starting to push for a greater degree of self reliance when it comes to their own defense expenditures? Speaker 1300:50:42They want to have a layer of insulation in place relative to the U. S. Election outcomes, etcetera. Is there a risk here in your mind that research budgets there could get crowded out, not so much in 2024, like I said, but more in 2025 and beyond? Speaker 500:50:58Undoubtedly, there's a higher degree of geopolitical tensions around the world and we follow that closely to see how it impacts the business. But I think specific to your question, at the end of the day, it's our strong conviction that good science gets funded and we're quite encouraged by the pipelines and the new modalities and the research that's underway. These pipelines are as full as they've ever been. Things are accelerating through particularly on cell and gene therapy. Again, I mentioned I think there's been 3 approvals year to date. Speaker 500:51:37I think there was a 4th one that came through even this morning. And so you see the rate of those things starting to pick up. So I think history has shown and I don't think we've seen anything here in the near term environment that would cause us to waiver on that, that this promising good science that's in flight here is going to get the funding it needs to progress. Speaker 1300:52:01Thanks, Michael. Appreciate the time. Operator00:52:08The next question comes from Josh Boardman with Cleveland Research. Please go ahead. Speaker 300:52:14Good morning. Thanks for taking my questions. A couple for you. First, Brent or Michael, wondering if you could comment on how you think visibility in the 90 days. Are you seeing any improvement in regards to the team's ability to forecast sales here in the near or medium term? Speaker 300:52:32And then along those lines, can you talk about how or if you're seeing bulk orders come back into the business and how that impacts your ability to forecast? Speaker 500:52:46Yes. Thanks, Josh. Good to hear from you. A couple of things I would say about visibility. I think one of the remarks I may have made in my prepared remarks was just some of the early returns we're getting from our new structure to the business. Speaker 500:53:03It's easier to think about these businesses from a more simplified and then a more logical, in my opinion, structure to the business. It's easier to think about these businesses from a customer needs, research or production environment and it certainly aligns better with how our customers think about it as opposed to our historical approach from a geographic standpoint. So our operating reviews have become a lot more streamlined and a lot more straightforward, which from our perspective is certainly a helpful improvement. It's a relatively short order cycle business as I commented earlier. And so I wouldn't say we've seen really any meaningful change in that regard over the last 90 days or so. Speaker 500:53:44Our supply chains have largely normalized in both segments. So we're back to pretty healthy levels of service in our lab segment, which means we can satisfy most orders in a day or 2. On the production side, we're 2 to 3 months out, which is kind of pre COVID levels of performance there. So I'd say the visibility is similar. Now, of course, with an accelerating order book and improved building order book here that gives us a little bit more forward visibility on the production side of the business and certainly more confidence in underwriting the outlooks that we have here, which I think is encouraging. Speaker 500:54:28Your second question there around how we've seen a return for bulk orders. In our business model, if I think about the ingredients or buffers, excipients, our customers don't typically have the ability to store just elevated levels of product. And so they tend to sync their orders with their production campaigns. And consistent with kind of the destocking trends that we've seen that was more prevalent on single use than it was on the process ingredients for those reasons. And so I would say the size of the orders has been pretty consistent on the process ingredient side. Speaker 500:55:12And then on the single use side, I don't know, I'd say that we've seen a change in order size. We're certainly starting to see with the orders return, the positive indications of destocking presumably coming to an end here in the near term and good underlying levels of activity. Speaker 300:55:36Got it. Thanks, Michael. And then, wondering if you could talk a bit more about the pricing and share environment. You commented on contract wins. Any more context you could provide there? Speaker 300:55:46And then do you think you're seeing more account churn than normal this year? So does that pose any risk to pricing as the year plays out? Or would you see it more as a potential opportunity for share and maybe top line outperformance? Speaker 500:56:03Maybe take those in reverse order, maybe talking first about your questions on pricing, then I'll talk about share. On the pricing side, I would say the team has delivered another solid year of execution on this and executing on that playbook. We expect kind of 1 to 2 points of contribution coming from price that's primarily offsetting the COGS inflation that we are seeing. So pretty close to historical levels of contribution, I would say, coming from price. And I think the teams did a nice job putting that through and not a lot of noise around that at this stage. Speaker 500:56:47We'll see a little bit of step up in revenue in the Q2 as those price increases. We get the full phasing of those in the quarter. So pretty pleased about where we're at from a pricing standpoint and certainly one of the favorable drivers of margin that we do see. Share is a great story for us and certainly excited to talk about that. On the production side, I think we've got a long standing track record particularly in our bio materials and bioprocessing business of share growth. Speaker 500:57:16You typically see us outperforming the broader market on bioprocessing 300 basis points to 400 basis points. And again, even with the declines we saw in the quarter, I think that performance is as good as you're going to see and certainly again best in class. And even if you were to adjust for maybe our more modest exposure to China, I think that's still a true statement. On the lab side, we've talked a lot about our strong focus in the academia world. We continue to see nice growth there and nice penetration and a lot of new customer wins there, a lot of important contract renewals. Speaker 500:57:57That's an end market or a customer segment that historically has been a little bit more open to churn. I'm not sure we're seeing it any differently now. Maybe we're playing it a bit more aggressively now. But just with their more fixed budget environment and less sensitivity to maybe some of the high regulatory environment that a biopharma customer might have, that is an area that we think that we can continue to be successful with. So again, another great quarter here of we think share expansion in both of our segments. Speaker 300:58:39Got it. Thank you, Michael. Appreciate all the color. Operator00:58:46We have time for one final question today. And so our next question comes from the line of Patrick Donnelly with Citi. Please go ahead. Speaker 1000:58:56Hey, guys. Thanks for getting me in here. Michael, I know in the last call you talked a little bit about some of the margin pacing and even the exit rate potential this year. I guess with the bioprocessing order improvement, obviously, nice margin flow through on that, the cost savings plan. Obviously, Brent talked a lot about just the visibility there. Speaker 1000:59:15Can you talk about just the confidence on that margin exit rate and how you are viewing things on that front given the current trends? Speaker 500:59:23Yes, it's a really good question, Patrick. We've reaffirmed our full year guidance today, which I think does a couple of things for us. 1, it shows our confidence in the plan that we have in place. But with the margin outperformance that we drove in Q1, of course, that has the effect then of derisking the margin ramp that was necessary to hit the full year margin numbers. So I like that. Speaker 500:59:54Certainly, it's early in the year. Brent talked a bit today about our cost transformation initiative that seems to be ahead of plan. Still a lot of things to get done on that front this year, but we're focused on executing those and perhaps there'll be some upside as we get further into the year. But I think it's at this stage of where we're at in the calendar, prudent to kind of bank the outperformance in Q1, continue to drive hard on all the initiatives that we have in flight here and we'll keep you updated as we move through the quarter. But I think the read for me on this is just a bit of derisking here on being able to deliver that margin target for the full year. Speaker 1001:00:42That's helpful. And just a very quick one. I know some time is tight. But Brent, just on the debt pay down visibility, leverage exit rate, when you guys start to think about capital deployment getting back in the mix there? Thank you, guys. Speaker 301:00:56Yes, sure. Thanks, Patrick. Look, we continue to generate cash very well. We're holding our pre transformation cost cash flow guidance for the year. Just you do the math on that, it would certainly absent a meaningful increase in EBITDA will certainly be within 2025. Speaker 301:01:15I mean, we're absolutely committed to getting to adjusted net leverage of below 3 times. We're certainly doing what we can to accelerate that, but say we'll keep posting you every quarter and we're going to keep diligently grinding down the debt balance. Operator01:01:35Those are all the questions we have time for today. And so this concludes our question and answer session. I would now like to turn the call back over to Michael for any concluding remarks. Speaker 501:01:46Yes. Thank you. Comments today, we're encouraged by the at least You can tell from our comments today, we're encouraged by the leading indicators that we're seeing, particularly in the improving order book in bioprocessing. We're out of the gate strong with our cost transformation initiative. We're able to accelerate some savings into the Q1 here and I'm pleased with our progress here. Speaker 501:02:18So thank you all for joining us today. Certainly look forward to updating you when we meet next. Until then, be well everyone. Operator01:02:28Thank you everyone for joining us today. This concludes our call and you may now disconnect your lines.Read moreRemove AdsPowered by