James E. Davis
Chairman, Chief Executive Officer and President at Quest Diagnostics
Thanks Shawn and good morning, everyone. We delivered another strong quarter, with base business revenue growth of nearly 4% and total revenue growth of 2.5%, as well as continued improvement in productivity and profitability in the base business. This performance is due to growth of new physician and hospital customers, more favorable test mix that includes greater adoption of advanced diagnostics and continued strength in healthcare utilization. We also made progress improving our operational quality and efficiency through greater use of automation and AI.
In addition, we're excited to announce four acquisitions that meet our criteria for growth, profitability and returns and that will enable us to expand in strategic growth areas. Our planned acquisition of Lifelabs, a trusted name in laboratory services for millions of Canadians, will enable us to grow in Canada, which has a population that is growing and aging faster than in the US. Lifelabs is especially strong in two of Canada's largest and fastest growing provinces, British Columbia and Ontario, which collectively account for about half of the country's population. We are familiar with the Canadian market, having delivered reference testing to many providers there for over 20 years. Lifelabs has been one of those reference partners for about a decade, so we know first-hand that their business, team, and reputation is strong and provides a solid foundation for growth. We expect to complete the transaction by the end of this year.
Our recently announced acquisition of select lab assets of Allina Health, a leading non-profit health system will enable us to extend our reach in Minneapolis and throughout Minnesota and Wisconsin. We also announced our plans to acquire the outreach lab assets of OhioHealth, a nationally recognized charitable health system in Ohio. Both transactions will broaden our presence in geographic areas of the United States, where we've had limited access to providers due to the predominance of health system. These acquisitions show our ability to attract and partner with top growing health systems that share our commitment to expanding patient access to innovative and more affordable testing. We expect to complete both transactions in the third quarter.
We also completed our acquisition of PathAI Diagnostics, which provides a readymade platform on which to scale digital pathology and AI to help health systems and other providers improve quality, speed and efficiency in cancer diagnosis. These acquisitions take time and involve teams of dedicated individuals. I want to personally thank my Quest colleagues for delivering on our M&A strategy, and we will now turn our attention to the hard work of integrating these deals.
Now I'll recap our strategy and discuss highlights from the second quarter. Then Sam will provide detail on our financial results and talk about our updated financial guidance for 2024.
Our strategy to drive growth is focused on delivering solutions that meet the evolving needs of our core customers, physicians, hospitals, and consumers. We enable growth across our customer channels through advanced diagnostics with an intense focus on faster growing clinical areas including within brain health and molecular genomics and oncology. In addition, acquisitions are a key growth driver. With an emphasis on accretive outreach purchases as well as other independent labs.
Our strategy also includes driving operational improvements across the business, with the strategic deployment of automation and AI to improve quality, service, efficiency, and the workforce experience. Here are some updates on progress we have made in each of these areas. While we grew total volumes from diagnostic information services 1.1%, with base business volume growth of 1.7%, volumes from our base clinical business grew 3.2% in the second quarter due to the strength among physicians and hospitals.
In physician lab services, we delivered another quarter of high single-digit base business revenue growth. This growth was driven by continued strength in healthcare utilization as well as overall market growth and share gains due to new customer wins. We drove favorable test mix as well as growth in test per requisition, which we attribute to greater utilization of our expanding portfolio of advanced diagnostics. Finally, we also saw strong volume and revenue growth within Medicare advantage plans, where narrow network strategies direct testing to high quality, cost efficient options like Quest. Our broad health plan access, which extends to approximately 90% of covered lives in the US, enabled us to take advantage of high demand for lab services consistent with recent quarters. Health plans value our ability to improve access, scale innovation and drive costs out of healthcare. We are also working to develop opportunities to serve new geographies with our health plan partners.
In hospital lab services, we grew base business revenues by nearly 4%. Growth of reference testing remains higher than historical levels as hospitals struggle to fill open positions, especially in technical fields such as histotechnology, microbiology, and cytotechnology. Our advanced diagnostics portfolio provides a compelling alternative for hospitals to send us more reference work. Hospitals face several challenges, including high supply costs, high wages, and decisions about how and where to deploy their capital. Patients want better value from lab services as well as easier access plus, diagnostic innovation is evolving at a fast pace. These dynamics are contributing to an accelerating trend of outreach acquisitions, and professional lab service arrangements with the national labs. Our specialization and scale empower us to deliver a breadth of quality, innovative and accessible services that are often far more affordable for the patient. That's why top hospitals are choosing Quest for reference testing, professional lab services, and outreach asset sales that deliver quality and efficiency.
In consumer initiated testing, our consumer facing platform, questhealth.com grew total revenues nearly 40%, while base business revenues grew more than 50% versus the prior year. As we learn more about our customers as our portfolio expands, we are improving growth and marketing productivity. Today about 25% of our revenues are from existing customers and 20% of our revenues are from tests we introduced in the past year.
In advanced diagnostics, several key clinical areas drove double-digit revenue growth continuing the trend in recent quarters. This growth was particularly strong in brain health, women's health, particularly prenatal and hereditary genetics, and advanced cardiometabolic health. Our Alzheimer's disease portfolio was the primary driver of growth for our brain health offering. Demand was strong for our AD-Detect blood test, which assessed risk based on amyloid, p-tau, ApoE biomarkers. Demand was also strong for our CSF test options for aiding treatment decisions. Yesterday, we introduced our neurofilament light chain test, which helps assess neuronal damage that may signify Alzheimer's disease, as well as multiple sclerosis and other neurodegenerative conditions.
In molecular genomics and oncology, we are encouraged by early results of our Haystack MRD early experience program prior to the broad national launch later this year. Physicians from leading cancer institutions are using the Haystack MRD blood test to assess cancer recurrence and treatment response for a range of cancers, including colorectal, lung and breast. We also grew the body of evidence on clinical and economic value of ctDNA blood testing and cancer care. A study published in JAMA Health Forum in June, found that MRD testing could reduce costs for health plans, particularly commercial payers, by identifying patients that would benefit from chemotherapy after stage two colon cancer surgery. In addition, research presented at the June ASCO Conference showed that the Haystack MRD testing identified complete clinical response to immunotherapy for patients with colorectal cancer earlier than standard assessments such as PET, MRI and endoscopy scan. Finally, we recently expanded our Haystack research collaborations to include Lisata Therapeutics, which will use Haystack MRD to study an investigational treatment for advanced pancreatic cancer.
Turning to advanced cardiometabolic testing, we are seeing interest in several biomarkers that improve early detection of cardiovascular and metabolic diseases like diabetes and kidney disease. These include insulin resistance, which can identify prediabetes risk before A1c tests and ApoB, a more precise marker of heart attack risk than traditional lipid panels. They also include Lp(a), which is an inherited marker of heart disease risk found in up to 20% of the population and for which several therapies are now in development.
Turning to operational excellence. Our Invigorate program aims to deliver a targeted 3% annual cost savings and productivity improvements. During the quarter, we expanded our use of automation and AI in order to improve productivity as well as service levels and quality. For instance, we advanced our use of automation and front end specimen processing to now include five of our labs, bringing more of our processors to focus on value added work. We also expanded our AI capabilities in microbiology to include the ability to segregate out specimens with no evidence of microbial growth, so our medical sciences can concentrate on reviewing those with the greatest likelihood of disease. In addition, we broadened our use of AI in customer service to help our representatives access answers more quickly, improving their efficiency and service quality.
Now I'll turn it over to Sam to provide more details on our performance and our 2024 guidance. Sam?