NYSE:AORT Artivion Q2 2024 Earnings Report $22.92 -0.16 (-0.67%) Closing price 04/17/2025 03:59 PM EasternExtended Trading$22.94 +0.01 (+0.04%) As of 04/17/2025 04:07 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Earnings HistoryForecast Artivion EPS ResultsActual EPS$0.07Consensus EPS $0.03Beat/MissBeat by +$0.04One Year Ago EPSN/AArtivion Revenue ResultsActual Revenue$98.02 millionExpected Revenue$97.70 millionBeat/MissBeat by +$320.00 thousandYoY Revenue GrowthN/AArtivion Announcement DetailsQuarterQ2 2024Date8/8/2024TimeN/AConference Call DateThursday, August 8, 2024Conference Call Time4:30PM ETUpcoming EarningsArtivion's Q1 2025 earnings is scheduled for Monday, May 5, 2025, with a conference call scheduled at 4:30 PM ET. Check back for transcripts, audio, and key financial metrics as they become available.Q1 2025 Earnings ReportConference Call ResourcesConference Call AudioConference Call TranscriptSlide DeckPress Release (8-K)Quarterly Report (10-Q)Earnings HistoryCompany ProfileSlide DeckFull Screen Slide DeckPowered by Artivion Q2 2024 Earnings Call TranscriptProvided by QuartrAugust 8, 2024 ShareLink copied to clipboard.There are 8 speakers on the call. Operator00:00:00Greetings, and welcome to Artivion's Second Quarter 2024 Financial Conference Call. At this time, all participants are in a listen only mode. A question and answer session will follow the formal presentation. As a reminder, this conference is being recorded. I would now like to turn the conference over to your host, Lane Morgan. Operator00:00:27Thank you. You may begin. Speaker 100:00:29Good afternoon, and thank you for joining the call today. Joining me today from Atuvion's management team are Pat Matkin, CEO and Lance Berry, CFO. Before we begin, I'd like to make the following statements to comply with the Safe Harbor requirements of the Private Securities Litigation Reform Act of 1995. Comments made on this call that look forward in time involve risks and uncertainties and are forward looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. The forward looking statements include statements made as to the company's or management's intentions, hopes, beliefs, expectations or predictions of the future. Speaker 100:01:06These forward looking statements are subject to a number of risks, uncertainties, estimates and assumptions that may cause actual results to differ materially from these forward looking statements. Additional information concerning certain risks and uncertainties that may impact these forward looking statements is contained from time to time in the company's SEC filings and in the press release that was issued earlier today. You can also find a brief presentation with details highlighted on today's call on the Investor Relations section of the Artibian website. Now I'll turn it over to Artibian's CEO, Pat Mackin. Speaker 200:01:36Thanks, Lane, and good afternoon, everybody. We're very pleased with our Q2 performance, which capped a strong first half of twenty twenty four for Artivion, with which we made significant progress on our commercial, operational and financial goals. In the Q2 of 2024, we delivered constant currency revenue growth of 10% year over year, representing $98,000,000 in revenue and adjusted EBITDA growth of 35% year over year compared to the Q2 of 2023. More recently, we amended our credit facility and option purchase agreements with EndoSpan. The amended credit facility provides EndoSpan with additional funding subject to progress towards completion of the NexSys PMA, while the amended option purchase agreement significantly improves our acquisition terms for EndoSpan should we elect to exercise our option. Speaker 200:02:29From a financial perspective, our Q2 performance was led by Onex, which grew 15%, followed by Stentgrass, which grew 13% and BioGlue that grew 12%, followed by tissue processing at 7%, each when compared to the Q2 of 2023, all on a constant currency basis. In the second quarter, we also continue to benefit from our regulatory approvals in commercial footprint expansion in key international markets, especially in Latin America and Asia Pacific. As a whole, our results and regulatory achievements further validate our growth strategy and we remain laser focused on expanding access to our differentiated product portfolio in existing and new markets. From a product category perspective, as I just mentioned, On X revenues increased 15% year over year on a constant currency basis as we continue to take market share globally with the only mechanical aortic valve that can be maintained at an INR of 1.5 to 2.0. Based on feedback from the field, our recent market share gains and the proven clinical benefits of the On X aortic valve, we maintain our strong conviction that On X is the best aortic valve on the market and will continue to take market share worldwide. Speaker 200:03:47Meanwhile, as I indicated earlier, our stent graft revenues grew 13 percent on a constant currency basis in the Q2 compared to the same period last year. Our stent graft portfolio remains a key component of our growth strategy and we are encouraged by our strong results, which are driven by our differentiated product portfolio focused on the more complex segments of the stent graft market. Today, the products in our stent graft portfolio are primarily sold in Europe, where we leverage our existing direct infrastructure sales infrastructure and create a significant cross selling opportunities across our unique aortic products offering. Our pipeline consists largely of bringing these proven products to the U. S. Speaker 200:04:29And Japan markets, which represents a significant growth opportunity. We also saw strength in BioGlue during the 2nd quarter, which grew 12% on a constant currency basis. As we have discussed previously, we expect to see some variability in the growth rates of BioGlue from quarter to quarter, driven by the significant amount of stocking distributor business in this product line. On an annual basis, we expect BioGlue to grow in the mid single digit range. Lastly, on tissue processing, our revenues grew 7% year over year on a constant currency basis in Q2 as we annualize the benefits from the last year's pricing initiatives. Speaker 200:05:09We continue to expect the tissue business to grow double digits for the full year of 2024 as we further leverage increased supply of our proprietary Synagraft pulmonary valve and continue to benefit from our higher Ross procedure volumes. For those unfamiliar with the Ross procedure, it's a double valve procedure in which the patient's native pulmonary valve is replaced by the patient's defective aortic valve and then the patient's pulmonary valve is then replaced by a donated pulmonary valve. The Ross procedure is considered the best option for young to middle aged patients with a diseased aortic valve as it provides the best option for these patients to have a normal life expectancy. The use of the Ross procedure has increased rapidly over the last couple of months years due to significant long term data demonstrating these significant clinical benefits. Our Synagraft pulmonary valve has no competitive alternative and is the market leader in allografts used in these procedures. Speaker 200:06:08Further, revenues in the 2nd quarter were also driven by our continued progress in growth in Latin America and Asia Pacific, primarily through new regulatory approvals and commercial footprint expansion. Latin America and Asia Pacific delivered constant currency revenue growth of 25% and 15%, respectively, compared to the Q2 of last year. We continue to anticipate strong revenue growth for both regions for the full year and over the coming years as we continue to leverage our industry leading product portfolio in these regions. We are also excited about the progress of our partner EndoSpan is continuing to make on the U. S. Speaker 200:06:47IDE TRIONF trial for the Nexus aortic arch stent graft system. As of today, there have been 50 of the 60 primary endpoint patients enrolled in the chronic dissection arm. Given this current enrollment, patients are scheduled for procedures, we expect to complete this trial by the end of 2024. Assuming the trial endpoints are met, Nexus remains on track for approval in the second half of twenty twenty six. As a reminder, aortic arch disease patients with aneurysms and dissections who receive treatment have previously had little choice before Nexus, but to undergo open chest surgery, which is an invasive and risky operation associated with lengthy hospitalizations and prolonged recuperation. Speaker 200:07:34Nexus is a highly differentiated technology that transforms a complex surgical aortic arch repair into a minimally invasive endovascular procedure. In 2019, we secured exclusive distribution rights for Nexus in Europe and began leveraging our existing European direct sales organization to expand access to the technology and drive revenue growth. Based on our experience in Europe, we continue to see a significant global opportunity for Nexus, which has been estimated on an annual global basis to be around 6 $100,000,000 Also in 2019, we provided a credit facility to EndoSpan to support the Nexus US ID trial and commercial operations. We also had entered into an option agreement to acquire EndoSpan until 90 days following the receipt of an FDA approval for Nexus. Recently in July, we amended these two agreements, which has resulted in 3 major changes that Lance will cover shortly. Speaker 200:08:33We view our revised agreements with EndoSpan as an investment in the next frontier of aortic arch surgery. We also view it as a potential opportunity to meaningfully expand our total addressable market on significantly more favorable terms than we had before. We also continue to anticipate PMA approval for AMDS in 2025, which as we have discussed, would open up an addressable market here in the U. S. For about $150,000,000 with no competitive alternatives. Speaker 200:09:03In summary, we are very excited about our Q2 performance and look forward to sustaining our momentum throughout 2024 and beyond by driving continued growth in On X, stent grafts and our SyneGraft Pulmonary Valve business by further expanding our global footprint in Asia Pacific and Latin America. With that, I'll now turn the call over to Lance. Speaker 300:09:22Thanks, Pat, and good afternoon, everyone. Before I begin, I'd like to remind you to please refer to our press release published earlier today for information regarding our non GAAP results, including a reconciliation of these results to our GAAP results. Additionally, all percentage changes discussed will be on a year over year basis and revenue growth rates will be in constant currency unless otherwise noted. Total revenues were $98,000,000 for the Q2 of 2024, up 10% compared to Q2 of 2023. Adjusted EBITDA increased approximately 35% from $13,800,000 to $18,600,000 in the Q2 of 2024. Speaker 300:10:02Adjusted EBITDA margin was 19% in the 2nd quarter, a 3 50 basis point improvement over the prior year driven by a 3 20 basis point reduction in general and administrative and marketing expense as a percentage of sales. We continue to believe our sales and G and A infrastructure is very scalable and the significant leverage we have produced in the first half of the year supports our belief. From a product line perspective, On X revenues increased 15%, scent craft revenues grew 13%, BioGlue revenues grew 12% and tissue processing revenues grew 7% in the Q2 of 2024. I would like to proactively note that other revenue declined approximately $1,300,000 42% in the Q2 of 2024. We did not break this segment out by product as it is relatively nominal to the business overall. Speaker 300:10:56However, I do want to provide some additional color on these results. The decline in Q2 was driven by the timing of PerClot orders from Baxter as they work to manage down inventory levels. The order decline also had a modest negative impact to adjusted EBITDA in Q2. Though the underlying end user sales of PerClot are continuing to ramp up, we expect these inventory dynamics to continue through the balance of 2024. Excluding this impact, our underlying business grew 11% in the Q2 of 2024 compared to Q2 of 2023. Speaker 300:11:30On a regional basis, revenues in Latin America increased 25%, Asia Pacific increased 15%, EMEA increased 13% and North America increased 5%, all compared to the Q2 of 2023. As anticipated, gross margins were 64.6% in Q2, a slight decrease from 65 point 1% compared to the Q2 of 2023. The decrease was due to normal fluctuations in geographic and product mix. Q2 margins were in line with the gross margins we saw in Q1 and in line with our full year expectation. General, administrative and marketing expenses in the Q2 were $49,300,000 compared to $57,200,000 in the Q2 of 2023. Speaker 300:12:16Non GAAP general, administrative and marketing expenses were $47,300,000 in the 2nd quarter compared to $45,900,000 in the Q2 of 2023, representing 3 20 basis points of leverage. R and D expenses for the 2nd quarter were $7,500,000 compared to $7,400,000 in the Q2 of 2023. We still anticipate full year R and D spend as a percentage of sales to be relatively flat to prior year. Interest expense net of interest income was $8,000,000 as compared to $6,100,000 in the prior year. Other income expense included foreign currency translation gains of approximately $900,000 this quarter. Speaker 300:13:01Free cash flow was $3,600,000 in the Q2 of 2024. Importantly, we continue to expect free cash flow to be positive for the full year 2024. As of June 30, we had approximately $55,000,000 in cash $313,600,000 in debt, net of $6,800,000 of unamortized loan origination costs. It is important to note that this does not contemplate the impact of our recently closed amendment agreement with EndoSpan, which I will speak to shortly. Further, we do not anticipate the need to raise additional capital to fund our debt obligations, our investments in our channels or our pipeline in the foreseeable future. Speaker 300:13:41Our net leverage at the end of Q2 was 4.1, down from 4.7 in prior year. At the midpoint of our EBITDA guidance range, we expect net debt leverage to be closer to 3.5 by the end of the year and to continue to decrease in 2025. In regard to the recently amended credit facility and option purchase agreements with EndoSpan, we are pleased with the combined results of these three major changes. First, Artivion will now provide additional loans to EndoSpan of up to $25,000,000 in 3 tranches, which we expect to fund with free cash flow. 2nd, the upfront payment associated with the purchase option is reduced by $75,000,000 and is now $135,000,000 after offsetting the loans. Speaker 300:14:28And third, the $100,000,000 minimum payout for the earn out is eliminated. To reiterate Pat's comments, we view the amended agreements as an investment in the future of aortic repair, while simultaneously providing Artivion with greater financial flexibility should we exercise our option to acquire EndoSpan. And now for our outlook for the remainder of 2024. Given our momentum in the first half of the year, we are raising fiscal year 2024 revenue guidance and now expect constant currency revenue growth of between 10% 12% compared to the previous range of 9% to 12%. We expect reported revenues to be in the range of $388,000,000 to $396,000,000 compared to our previous range of $386,000,000 to $396,000,000 At current rates, we expect FX to have a negligible impact on full year revenue growth rates. Speaker 300:15:26With our continued top line revenue growth and general expense management through Q2, we are raising our fiscal year 2020 4 adjusted EBITDA guidance and now expect to be in the range of $69,000,000 to $72,000,000 for the full year 2024, representing a 28% to 34% growth over 2023 and 280 basis points of adjusted EBITDA margin expansion at the midpoint of our ranges. This compares to the previous guidance range of $68,000,000 to $72,000,000 representing 26% to 34% growth over 2023. As a reminder, we expect gross margins to remain at levels similar to 2023 and continue to expect to drive significant leverage from our global sales force and G and A infrastructure. Additionally, R and D expense is expected to remain relatively flat as a percentage of sales. With that, I will turn the call back to Pat for his closing comments. Speaker 200:16:21Thanks Lance. So as you've heard, we're very pleased with our 2nd quarter results, which reflect the continued strength of our highly differentiated and highly dependable product portfolio. We are more excited than ever for our near term and medium term growth potential as we further expand our presence across markets with little existing competition and no anticipated new entrants. By leveraging our existing global infrastructure and our ability to cross sell into well established account base. We are committed to delivering strong revenue growth and EBITDA growth through the balance of 2024 that expect to be driven by the following: 1st, strong growth in our stent graft business driven by our innovative portfolio second, market share increases for On X third, continued expansion in Asia Pacific and Latin America from our channel investment as well as new regulatory approvals 4th, expense leverage driven by our global sales force and G and A infrastructure and 5th, continued adjusted EBITDA margin expansion and positive free cash flow. Speaker 200:17:22Finally, I want to thank all the employees around the world for their continued dedication to our mission of being a leading partner to surgeons focused on aortic diseases. With that, operator, please open the line for questions. Operator00:17:34Thank you. At this time, we'll be conducting a question and answer Our first question comes from Frank Tackanan with Lake Street Capital. Please proceed with your question. Speaker 400:18:11Great. Thanks for taking the questions. Congrats on all the progress. I wanted to start with one on EBITDA. Obviously, the leverage profile continues to be impressive. Speaker 400:18:20Saw the updated guidance for the back half of the year. Help us understand, in weighing investments into the business and EBITDA growth through the end of the year. I know in previous years typically you've had a little more EBITDA in the back half as a percentage of the full year versus the front half and it's about equal is what the guidance is implying for the back half. So is there maybe some additional investment going on there or is that just in the interest of maybe a little bit of conservatism? Speaker 300:18:47Yes. There's a little bit of spend timing between 2nd and third quarter. Obviously, we had a really strong second quarter for EBITDA and we do expect a very strong second half. I do think we'll see Q3 growth probably be a little bit lighter than we saw in Q2 just due to timing. So it's really not anything more than that. Speaker 300:19:12And as a reminder, we don't have a ton of seasonality, but Q3 is typically our lowest revenue quarter, which does have a little bit impact Q2 to Q3. Speaker 400:19:26Got it. That's helpful. And then maybe just for my second one, I'll ask a follow-up on Onex. Maybe can you break out unit growth versus ASP and then talk about pricing in that line item? Obviously, you continue to take shares. Speaker 400:19:38There are still additional opportunity to raise price in the On X portfolio? Speaker 200:19:43Yes. We don't really break out the price volume. It's not something we typically do. What I can tell you is 15% growth of our Mechanical Valves segment is we continue I think in the last 6 or 7 years, we've grown this business on average of around 15% over the last I think since we acquired the company. We still have a lot of opportunity internationally, and we're still taking share in the U. Speaker 200:20:11S. Even from our high share position. We're also increasing price. I mean, our recent post approval data that came out shows an 85% reduction in major bleeding, which moves it a lot closer to a bioprosthetic valve. We're also seeing recent data that's come out on mechanical versus bioprosthetic data that's very compelling for people moving to the On X valve in patients under 70. Speaker 200:20:39So we're very bullish on what we have and we feel like we've got the best valve and we're going to keep taking share. Speaker 400:20:48Got it. Thanks for taking the questions. Congrats again. Speaker 500:20:51Thanks Frank. Operator00:20:54Our next question comes from Suraj Kalia with Oppenheimer. Please proceed with your question. Speaker 500:21:00Hey, Pat, Lance, can you hear me all right? Speaker 200:21:03Yes, we can hear you fine, Suraj. Speaker 500:21:05Congrats on all the progress. So Pat, just keying off from the last comment you made to the previous question. Can you I believe last quarter, On X was about 30% OUS share, 50% plus U. S. Yes. Speaker 500:21:24Can you give us some color as to where we are exiting Q2? Speaker 200:21:30Yes. So what I will tell you without getting into the granularity is, we're growing both markets double digits. As I just said, we've got your share comments are pretty accurate, right? We've got about a 30% global. And when you break that down, it's like over 50% in the U. Speaker 200:21:48S. And 20%, 25% internationally. So we clearly have more opportunity internationally. But I think the big story on On X is really all the dynamics that are going on. On. Speaker 200:22:04Frankly, it's our aortic valve portfolio in patients under 65. Our ROS, our pulmonary valve for the ROS, we have the only Synagraft valve for that. It's growing double digits consistently On X is growing consistently double digits with our new post approval data. As you well know, you're very well read on the data. It's a dynamic market, but there's kind of more and more negative data coming out on TAVR in patients under 65, on bioprosthetic in patients under 65. Speaker 200:22:34The difference in reoperation and mortality out to 15 years benefits mechanical valves. And they've seen lots of reoperations in patients getting TAVR under 65. And I think that's a real problem, right? I mean, there's a difference in reauthor mortality at 15 years. These are 65 year olds. Speaker 200:22:53That's a big deal. So again, I think we've got a great story with the On X valve. We're just going to keep telling our story. Speaker 500:23:01Got it. Pat, I'm drawing the blank here, so please forgive me. On neXus, remind me, when you talk about chronic aortic dissection, right, in the need and the 600,000,000 TAM, I get that. The enrollment in the trial, again, if memory serves me correctly, it's like 5, 6 patients per quarter. Is that by design? Speaker 500:23:27Is that due to patient selection? Just kind of help us understand, take a leap from here from the trial enrollment to if you'll acquire and understand how Nexus layout and whatnot in commercial adoption, how should we think about the speed of adoption? Speaker 200:23:49Yes. So I would say there's a lot in that. I think both in both of our messages Lance and I commented on, we're making an investment in the future of aortic technology. Patients today who have to have a chronic dissection repaired and we have technology for that, you're looking at a 7 to 10 day ICU stay. We have patients in Europe that are getting the Nexus device that are standing out in front of the hospital the next day, right? Speaker 200:24:16So it's a big deal. But like any new technology, there's going to be an evolution, right? So what we're talking about right now is a single branch into the annominate. That's the U. S. Speaker 200:24:26ID trial called TRIONF. We've enrolled 50 out of 60. We should enroll that by the end of the year. I think that will have modest uptake when we launch it, but we'll be looking to start a 2 branch trial probably right after that. And we think that that technology can capture half the chronic dissections in the world. Speaker 200:24:45So it's a big deal and we're very interested in the space and which is why we recut the deal. The data has been excellent and the trial is almost done. So yes, we're very excited and look forward to having it report out. Speaker 500:24:59Got it. Pat, final question, I'll hop back in queue. In terms of your sales reps, walk us through how does the bell curve look for sales rep productivity? At this stage in Artifion's evolution, are we at that point in terms of higher elasticity to sales rep commission structure? Just kind of put this thing together, how you're seeing the direct force, the sales force, U. Speaker 500:25:29S. Versus OUS? Gentlemen, thank you for taking my questions. Speaker 200:25:32Yes. Thanks, Raj. So to me, I think this is one of the real benefits you're seeing and how we can grow top line 10% and bottom line 35%. We've got an excellent sales force. You talked about here in the U. Speaker 200:25:44S. As well as in Europe and some of the international markets. Most of our reps in the U. S. Have 10 years with the company. Speaker 200:25:52They know their customers. They call on them for ROS procedures with Synagraft. They call on them with On X for aortic procedure. They call them with BioGlue. When we get ANDS approved, they will call on them for that. Speaker 200:26:03And when we get our frozen elephant trunk approved, they'll call on them for that. So the cardiac surgery segment is a much different segment than many of the other kind of medtech spaces. You don't have to scale your sales force kind of 1 to 1 with your revenue. And you see that in our leverage. So we're very excited about bringing our AMDS when it gets approved in late 2025. Speaker 200:26:27But we can just drop it in our existing reps' bags and see a lot of that incremental profitability go right to the bottom line, which has been part of our story all along. Operator00:26:47Our next question comes from Rick Wise with Stifel. Please proceed with your question. Speaker 600:26:52Hi, Pat. Hi, Lance. This is John on for Rick today. Another strong quarter in this 2Q. Just wanted to sort of look ahead, think about the bigger picture. Speaker 600:27:02You've provided guidance or a rough structure at your 2022 Analyst Day and 2025 plus but just thinking about the new approvals potentially coming through, the new potential products you're adding to the portfolio and the areas where you're innovating, just wanted to get your sense on the longer term bigger picture looking hedge. Should we expect more of the same sort of double digit growth 2025 plus? Speaker 300:27:30Yes. So we've stayed away from kind of re upping long term guidance. We're just now finishing we gave some formal targets back in 2022 through 2024. So hadn't quite finished those out yet. So we're not sending out some new ones. Speaker 300:27:47But I think we feel good about saying like, look, if you think about us looking further out with the portfolio we have now and then the things in our pipeline, we should be able to be a consistent double digit grower for an extended period of time. And then really we ought to be able to drive a lot of leverage off that. So we ought to be able to grow the bottom line really at least 2x the top line. I mean if you look this year our guidance is 3x the top line at the midpoint and we're not committing to that forever going forward. But there's a lot of leverage opportunity in the business. Speaker 300:28:25And our core business is very defendable. You've got PMA based products in markets with not a lot of competition that are really unlikely to see new entrants. And then we have this amazing pipeline. So at a high level, we feel comfortable about double digit growth and growing the bottom line at least 2x that. Speaker 600:28:47Got it. Now I appreciate the color. And just as I look to the rest of the year, I realized last year, maybe in the second quarter, you guys put through a price increase. Just wanted to think about that in 2024, 2025. Is there another opportunity for Artivion to potentially take price? Speaker 600:29:08Or are you all done for a bit? Speaker 200:29:12Yes. I've talked about this on previous calls. I mean, we look at the portfolio. We look at how differentiated our product line is. And in some cases, we have significant clinical outcomes where we spent 1,000,000 of dollars generating the data that nobody else has. Speaker 200:29:29And Synagraft Pulmonary Valve is the perfect poster for that. We spent $1,000,000 developing the technology, patenting it and getting the clinical data that now has 25 year results, which is the best valve operation for, I would say, a patient under 55 years old. For something like that, we're going to charge a premium price for it because it's it warrants. I talked about Onyx. We just invested 1,000,000 of dollars in the post approval trial. Speaker 200:29:57And we came out with data that nobody else can match. And I think that that clinical data warrants a higher price. So we're not going to go through kind of every line item on the portfolio, but you can get a sense of the things that are highly differentiated backed by patents, backed by compelling clinical data, we will charge what we think is a fair price for those. Speaker 600:30:22I appreciate the color. Thanks for taking the questions. Operator00:30:38Our next question comes from Jeffrey Cohen with Ladenburg Thalmann. Please proceed with your question. Speaker 700:30:45Hey, Pat and Lance. How are you? Speaker 200:30:47Hey, Jeff. Speaker 700:30:48Thanks for taking our questions in advance. Just a few from our end. I heard Lance, a call out on Baxter and the other revenue line. Are there any puts and takes there on Pericloud? Or do you have any clarity or see through in how things are going on their side? Speaker 300:31:06Yes. I mean, I guess, first of all, at a high level, I mean, it's not really very meaningful to us. So I mean, it's tiny to Baxter. Just to put it in context, the only reason we brought it up is it just sticks out because the decline was so significant. And I mean our visibility is not great to underlying sales, but our understanding is they're continuing to ramp up. Speaker 300:31:33And this is just some basic managing the balance sheet on their side and doing being good about inventory management is creating some fluctuation in what's a very small line item, so it just jumps off the page. So in general, we're not going to talk about Baxter's business. That's their business. But again, I would just say it's not meaningful to us, so it's really not meaningful to them. Speaker 700:31:57Got it. Okay. And then secondly, could you talk about Baguio a little bit? It looked extremely strong for the Q2 coming into $18.55 So any commentary there or any outlook as far as the back half of the year or general commentary on the strength or specific geographies? Speaker 200:32:17Yes. I think that we mentioned Lance mentioned it in his comments, right? I mean, BioGlue grew like 1% in the Q1 and it grew 12% in the Q2. Don't plug 12% in your model because it's a very kind of lumpy business. We have a lot of indirect. Speaker 200:32:33We sell in 110 countries around the world. So you can the phasing of every 90 days, you get some bigger in some quarters, less in other quarters. But on average, we think that that product line is going to grow kind of in the mid single digit. So obviously, we had a very good quarter this quarter and it's obviously extremely Speaker 700:32:53profitable. Got it. And then lastly for us, could you talk a little bit about the aortextent graft portfolio for the quarter, areas of weakness or strength or any specific SKUs or items which are doing well or not as Speaker 200:33:09well? Yes. We don't break. I mean, we made a move, I think a couple of years ago to kind of put these large buckets in place. I can tell you the area that we focus on, which is the highly differentiated, faster growing, higher margin stent graft segment, we're growing double digits in every category. Speaker 200:33:28I'm not going to break out line items and give competitors roadmaps. So we're doing extremely well. Frankly, even in the non differentiated, the more competitive stuff, we're growing double digits. So the whole portfolio is doing really well. Speaker 700:33:44Perfect. That does it for us. Thanks for taking our questions. Nice quarter. Speaker 200:33:47Thanks, Jeff. Operator00:33:50Mr. Mackin, there are no further questions at this time. I'd like to turn the floor back over to management for closing comments. Speaker 200:33:57Yeah. Well, thanks for joining. Again, we are excited about the quarter and thanks for joining the call. We've obviously got a lot of great opportunity in front of us. As you heard both Lance and I talk, we're executing well. Speaker 200:34:08We're growing 10% top line and 35% on the bottom line. Again, this year, we did it last year. We just talked about our kind of we're not giving guidance, but we think we can grow double digits top line and twice that on the bottom line. We've got an exciting pipeline, a great channel, a great portfolio, highly differentiated and we're very excited about building this aorta company and treating and taking care of more patients so our surgeons have what they need from a technology standpoint. So thanks for joining. Operator00:34:40This concludes today's conference. You may disconnect your lines at this time and we thank you for your participation.Read morePowered by Conference Call Audio Live Call not available Earnings Conference CallArtivion Q2 202400:00 / 00:00Speed:1x1.25x1.5x2x Earnings DocumentsSlide DeckPress Release(8-K)Quarterly report(10-Q) Artivion Earnings HeadlinesUnpacking Q4 Earnings: Artivion (NYSE:AORT) In The Context Of Other Medical Devices & Supplies - Cardiology, Neurology, Vascular StocksApril 15, 2025 | finance.yahoo.comInvestors in Artivion (NYSE:AORT) have seen returns of 15% over the past yearApril 14, 2025 | finance.yahoo.comThe Trump Dump is starting; Get out of stocks now?The first 365 days of the Trump presidency… Will be the best time to get rich in American history.April 19, 2025 | Paradigm Press (Ad)Artivion (AORT): Buy, Sell, or Hold Post Q4 Earnings?March 28, 2025 | msn.comDo Options Traders Know Something About Artivion (AORT) Stock We Don't?March 24, 2025 | finance.yahoo.comArtivion to Participate in the Oppenheimer 35th Annual Healthcare MedTech & Services ConferenceMarch 4, 2025 | prnewswire.comSee More Artivion Headlines Get Earnings Announcements in your inboxWant to stay updated on the latest earnings announcements and upcoming reports for companies like Artivion? Sign up for Earnings360's daily newsletter to receive timely earnings updates on Artivion and other key companies, straight to your email. Email Address About ArtivionArtivion (NYSE:AORT) manufactures, processes, and distributes medical devices and implantable human tissues worldwide. The company provides BioGlue, a polymer consisting of bovine blood protein and an agent for cross-linking proteins for cardiac, vascular, neurologic, and pulmonary procedures; cardiac preservation services; PhotoFix, a bovine pericardial patch; and aortic arch stent grafts including E-vita Open Plus and E-vita Open Neo. It offers E-xtra design engineering systems for the treatment of aortic vascular diseases; E-nside, an off-the-shelf stent graft for the treatment of thoraco-abdominal disease; E-vita THORACIC 3G for the endovascular treatment of thoracic aortic aneurysms; E-ventus BX, a balloon-expandable peripheral stent graft for the endovascular treatment of renal and pelvic arteries; E-liac to treat aneurysmal iliac arteries, and aneurysmal iliac side branches; and E-tegra, a stent graft system for the treatment of infrarenal abdominal aortic aneurysms. In addition, the company offers synthetic vascular grafts for use in open aortic and peripheral vascular surgical procedures; PerClot, an absorbable powdered hemostat for use in surgical procedures; cardiac laser therapy products for angina treatment; CryoVein femoral vein and CryoArtery femoral artery vascular preservation services; On-X prosthetic aortic and mitral heart valves and the On-X ascending aortic prosthesis; CarbonAid CO2 diffusion catheters and Chord-X ePTFE sutures for mitral chordal replacement; and ascyrus medical dissection stents, as well as pyrolytic carbon coating services to medical device manufacturers. It serves physicians, hospitals, and other healthcare facilities, as well as cardiac, vascular, thoracic, and general surgeons. The company was formerly known as CryoLife, Inc. and changed its name to Artivion, Inc. in January 2022. Artivion, Inc. was incorporated in 1984 and is headquartered in Kennesaw, Georgia.View Artivion ProfileRead more More Earnings Resources from MarketBeat Earnings Tools Today's Earnings Tomorrow's Earnings Next Week's Earnings Upcoming Earnings Calls Earnings Newsletter Earnings Call Transcripts Earnings Beats & Misses Corporate Guidance Earnings Screener Earnings By Country U.S. Earnings Reports Canadian Earnings Reports U.K. Earnings Reports Latest Articles Archer Aviation Unveils NYC Network Ahead of Key Earnings Report3 Reasons to Like the Look of Amazon Ahead of EarningsTesla Stock Eyes Breakout With Earnings on DeckJohnson & Johnson Earnings Were More Good Than Bad—Time to Buy? 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There are 8 speakers on the call. Operator00:00:00Greetings, and welcome to Artivion's Second Quarter 2024 Financial Conference Call. At this time, all participants are in a listen only mode. A question and answer session will follow the formal presentation. As a reminder, this conference is being recorded. I would now like to turn the conference over to your host, Lane Morgan. Operator00:00:27Thank you. You may begin. Speaker 100:00:29Good afternoon, and thank you for joining the call today. Joining me today from Atuvion's management team are Pat Matkin, CEO and Lance Berry, CFO. Before we begin, I'd like to make the following statements to comply with the Safe Harbor requirements of the Private Securities Litigation Reform Act of 1995. Comments made on this call that look forward in time involve risks and uncertainties and are forward looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. The forward looking statements include statements made as to the company's or management's intentions, hopes, beliefs, expectations or predictions of the future. Speaker 100:01:06These forward looking statements are subject to a number of risks, uncertainties, estimates and assumptions that may cause actual results to differ materially from these forward looking statements. Additional information concerning certain risks and uncertainties that may impact these forward looking statements is contained from time to time in the company's SEC filings and in the press release that was issued earlier today. You can also find a brief presentation with details highlighted on today's call on the Investor Relations section of the Artibian website. Now I'll turn it over to Artibian's CEO, Pat Mackin. Speaker 200:01:36Thanks, Lane, and good afternoon, everybody. We're very pleased with our Q2 performance, which capped a strong first half of twenty twenty four for Artivion, with which we made significant progress on our commercial, operational and financial goals. In the Q2 of 2024, we delivered constant currency revenue growth of 10% year over year, representing $98,000,000 in revenue and adjusted EBITDA growth of 35% year over year compared to the Q2 of 2023. More recently, we amended our credit facility and option purchase agreements with EndoSpan. The amended credit facility provides EndoSpan with additional funding subject to progress towards completion of the NexSys PMA, while the amended option purchase agreement significantly improves our acquisition terms for EndoSpan should we elect to exercise our option. Speaker 200:02:29From a financial perspective, our Q2 performance was led by Onex, which grew 15%, followed by Stentgrass, which grew 13% and BioGlue that grew 12%, followed by tissue processing at 7%, each when compared to the Q2 of 2023, all on a constant currency basis. In the second quarter, we also continue to benefit from our regulatory approvals in commercial footprint expansion in key international markets, especially in Latin America and Asia Pacific. As a whole, our results and regulatory achievements further validate our growth strategy and we remain laser focused on expanding access to our differentiated product portfolio in existing and new markets. From a product category perspective, as I just mentioned, On X revenues increased 15% year over year on a constant currency basis as we continue to take market share globally with the only mechanical aortic valve that can be maintained at an INR of 1.5 to 2.0. Based on feedback from the field, our recent market share gains and the proven clinical benefits of the On X aortic valve, we maintain our strong conviction that On X is the best aortic valve on the market and will continue to take market share worldwide. Speaker 200:03:47Meanwhile, as I indicated earlier, our stent graft revenues grew 13 percent on a constant currency basis in the Q2 compared to the same period last year. Our stent graft portfolio remains a key component of our growth strategy and we are encouraged by our strong results, which are driven by our differentiated product portfolio focused on the more complex segments of the stent graft market. Today, the products in our stent graft portfolio are primarily sold in Europe, where we leverage our existing direct infrastructure sales infrastructure and create a significant cross selling opportunities across our unique aortic products offering. Our pipeline consists largely of bringing these proven products to the U. S. Speaker 200:04:29And Japan markets, which represents a significant growth opportunity. We also saw strength in BioGlue during the 2nd quarter, which grew 12% on a constant currency basis. As we have discussed previously, we expect to see some variability in the growth rates of BioGlue from quarter to quarter, driven by the significant amount of stocking distributor business in this product line. On an annual basis, we expect BioGlue to grow in the mid single digit range. Lastly, on tissue processing, our revenues grew 7% year over year on a constant currency basis in Q2 as we annualize the benefits from the last year's pricing initiatives. Speaker 200:05:09We continue to expect the tissue business to grow double digits for the full year of 2024 as we further leverage increased supply of our proprietary Synagraft pulmonary valve and continue to benefit from our higher Ross procedure volumes. For those unfamiliar with the Ross procedure, it's a double valve procedure in which the patient's native pulmonary valve is replaced by the patient's defective aortic valve and then the patient's pulmonary valve is then replaced by a donated pulmonary valve. The Ross procedure is considered the best option for young to middle aged patients with a diseased aortic valve as it provides the best option for these patients to have a normal life expectancy. The use of the Ross procedure has increased rapidly over the last couple of months years due to significant long term data demonstrating these significant clinical benefits. Our Synagraft pulmonary valve has no competitive alternative and is the market leader in allografts used in these procedures. Speaker 200:06:08Further, revenues in the 2nd quarter were also driven by our continued progress in growth in Latin America and Asia Pacific, primarily through new regulatory approvals and commercial footprint expansion. Latin America and Asia Pacific delivered constant currency revenue growth of 25% and 15%, respectively, compared to the Q2 of last year. We continue to anticipate strong revenue growth for both regions for the full year and over the coming years as we continue to leverage our industry leading product portfolio in these regions. We are also excited about the progress of our partner EndoSpan is continuing to make on the U. S. Speaker 200:06:47IDE TRIONF trial for the Nexus aortic arch stent graft system. As of today, there have been 50 of the 60 primary endpoint patients enrolled in the chronic dissection arm. Given this current enrollment, patients are scheduled for procedures, we expect to complete this trial by the end of 2024. Assuming the trial endpoints are met, Nexus remains on track for approval in the second half of twenty twenty six. As a reminder, aortic arch disease patients with aneurysms and dissections who receive treatment have previously had little choice before Nexus, but to undergo open chest surgery, which is an invasive and risky operation associated with lengthy hospitalizations and prolonged recuperation. Speaker 200:07:34Nexus is a highly differentiated technology that transforms a complex surgical aortic arch repair into a minimally invasive endovascular procedure. In 2019, we secured exclusive distribution rights for Nexus in Europe and began leveraging our existing European direct sales organization to expand access to the technology and drive revenue growth. Based on our experience in Europe, we continue to see a significant global opportunity for Nexus, which has been estimated on an annual global basis to be around 6 $100,000,000 Also in 2019, we provided a credit facility to EndoSpan to support the Nexus US ID trial and commercial operations. We also had entered into an option agreement to acquire EndoSpan until 90 days following the receipt of an FDA approval for Nexus. Recently in July, we amended these two agreements, which has resulted in 3 major changes that Lance will cover shortly. Speaker 200:08:33We view our revised agreements with EndoSpan as an investment in the next frontier of aortic arch surgery. We also view it as a potential opportunity to meaningfully expand our total addressable market on significantly more favorable terms than we had before. We also continue to anticipate PMA approval for AMDS in 2025, which as we have discussed, would open up an addressable market here in the U. S. For about $150,000,000 with no competitive alternatives. Speaker 200:09:03In summary, we are very excited about our Q2 performance and look forward to sustaining our momentum throughout 2024 and beyond by driving continued growth in On X, stent grafts and our SyneGraft Pulmonary Valve business by further expanding our global footprint in Asia Pacific and Latin America. With that, I'll now turn the call over to Lance. Speaker 300:09:22Thanks, Pat, and good afternoon, everyone. Before I begin, I'd like to remind you to please refer to our press release published earlier today for information regarding our non GAAP results, including a reconciliation of these results to our GAAP results. Additionally, all percentage changes discussed will be on a year over year basis and revenue growth rates will be in constant currency unless otherwise noted. Total revenues were $98,000,000 for the Q2 of 2024, up 10% compared to Q2 of 2023. Adjusted EBITDA increased approximately 35% from $13,800,000 to $18,600,000 in the Q2 of 2024. Speaker 300:10:02Adjusted EBITDA margin was 19% in the 2nd quarter, a 3 50 basis point improvement over the prior year driven by a 3 20 basis point reduction in general and administrative and marketing expense as a percentage of sales. We continue to believe our sales and G and A infrastructure is very scalable and the significant leverage we have produced in the first half of the year supports our belief. From a product line perspective, On X revenues increased 15%, scent craft revenues grew 13%, BioGlue revenues grew 12% and tissue processing revenues grew 7% in the Q2 of 2024. I would like to proactively note that other revenue declined approximately $1,300,000 42% in the Q2 of 2024. We did not break this segment out by product as it is relatively nominal to the business overall. Speaker 300:10:56However, I do want to provide some additional color on these results. The decline in Q2 was driven by the timing of PerClot orders from Baxter as they work to manage down inventory levels. The order decline also had a modest negative impact to adjusted EBITDA in Q2. Though the underlying end user sales of PerClot are continuing to ramp up, we expect these inventory dynamics to continue through the balance of 2024. Excluding this impact, our underlying business grew 11% in the Q2 of 2024 compared to Q2 of 2023. Speaker 300:11:30On a regional basis, revenues in Latin America increased 25%, Asia Pacific increased 15%, EMEA increased 13% and North America increased 5%, all compared to the Q2 of 2023. As anticipated, gross margins were 64.6% in Q2, a slight decrease from 65 point 1% compared to the Q2 of 2023. The decrease was due to normal fluctuations in geographic and product mix. Q2 margins were in line with the gross margins we saw in Q1 and in line with our full year expectation. General, administrative and marketing expenses in the Q2 were $49,300,000 compared to $57,200,000 in the Q2 of 2023. Speaker 300:12:16Non GAAP general, administrative and marketing expenses were $47,300,000 in the 2nd quarter compared to $45,900,000 in the Q2 of 2023, representing 3 20 basis points of leverage. R and D expenses for the 2nd quarter were $7,500,000 compared to $7,400,000 in the Q2 of 2023. We still anticipate full year R and D spend as a percentage of sales to be relatively flat to prior year. Interest expense net of interest income was $8,000,000 as compared to $6,100,000 in the prior year. Other income expense included foreign currency translation gains of approximately $900,000 this quarter. Speaker 300:13:01Free cash flow was $3,600,000 in the Q2 of 2024. Importantly, we continue to expect free cash flow to be positive for the full year 2024. As of June 30, we had approximately $55,000,000 in cash $313,600,000 in debt, net of $6,800,000 of unamortized loan origination costs. It is important to note that this does not contemplate the impact of our recently closed amendment agreement with EndoSpan, which I will speak to shortly. Further, we do not anticipate the need to raise additional capital to fund our debt obligations, our investments in our channels or our pipeline in the foreseeable future. Speaker 300:13:41Our net leverage at the end of Q2 was 4.1, down from 4.7 in prior year. At the midpoint of our EBITDA guidance range, we expect net debt leverage to be closer to 3.5 by the end of the year and to continue to decrease in 2025. In regard to the recently amended credit facility and option purchase agreements with EndoSpan, we are pleased with the combined results of these three major changes. First, Artivion will now provide additional loans to EndoSpan of up to $25,000,000 in 3 tranches, which we expect to fund with free cash flow. 2nd, the upfront payment associated with the purchase option is reduced by $75,000,000 and is now $135,000,000 after offsetting the loans. Speaker 300:14:28And third, the $100,000,000 minimum payout for the earn out is eliminated. To reiterate Pat's comments, we view the amended agreements as an investment in the future of aortic repair, while simultaneously providing Artivion with greater financial flexibility should we exercise our option to acquire EndoSpan. And now for our outlook for the remainder of 2024. Given our momentum in the first half of the year, we are raising fiscal year 2024 revenue guidance and now expect constant currency revenue growth of between 10% 12% compared to the previous range of 9% to 12%. We expect reported revenues to be in the range of $388,000,000 to $396,000,000 compared to our previous range of $386,000,000 to $396,000,000 At current rates, we expect FX to have a negligible impact on full year revenue growth rates. Speaker 300:15:26With our continued top line revenue growth and general expense management through Q2, we are raising our fiscal year 2020 4 adjusted EBITDA guidance and now expect to be in the range of $69,000,000 to $72,000,000 for the full year 2024, representing a 28% to 34% growth over 2023 and 280 basis points of adjusted EBITDA margin expansion at the midpoint of our ranges. This compares to the previous guidance range of $68,000,000 to $72,000,000 representing 26% to 34% growth over 2023. As a reminder, we expect gross margins to remain at levels similar to 2023 and continue to expect to drive significant leverage from our global sales force and G and A infrastructure. Additionally, R and D expense is expected to remain relatively flat as a percentage of sales. With that, I will turn the call back to Pat for his closing comments. Speaker 200:16:21Thanks Lance. So as you've heard, we're very pleased with our 2nd quarter results, which reflect the continued strength of our highly differentiated and highly dependable product portfolio. We are more excited than ever for our near term and medium term growth potential as we further expand our presence across markets with little existing competition and no anticipated new entrants. By leveraging our existing global infrastructure and our ability to cross sell into well established account base. We are committed to delivering strong revenue growth and EBITDA growth through the balance of 2024 that expect to be driven by the following: 1st, strong growth in our stent graft business driven by our innovative portfolio second, market share increases for On X third, continued expansion in Asia Pacific and Latin America from our channel investment as well as new regulatory approvals 4th, expense leverage driven by our global sales force and G and A infrastructure and 5th, continued adjusted EBITDA margin expansion and positive free cash flow. Speaker 200:17:22Finally, I want to thank all the employees around the world for their continued dedication to our mission of being a leading partner to surgeons focused on aortic diseases. With that, operator, please open the line for questions. Operator00:17:34Thank you. At this time, we'll be conducting a question and answer Our first question comes from Frank Tackanan with Lake Street Capital. Please proceed with your question. Speaker 400:18:11Great. Thanks for taking the questions. Congrats on all the progress. I wanted to start with one on EBITDA. Obviously, the leverage profile continues to be impressive. Speaker 400:18:20Saw the updated guidance for the back half of the year. Help us understand, in weighing investments into the business and EBITDA growth through the end of the year. I know in previous years typically you've had a little more EBITDA in the back half as a percentage of the full year versus the front half and it's about equal is what the guidance is implying for the back half. So is there maybe some additional investment going on there or is that just in the interest of maybe a little bit of conservatism? Speaker 300:18:47Yes. There's a little bit of spend timing between 2nd and third quarter. Obviously, we had a really strong second quarter for EBITDA and we do expect a very strong second half. I do think we'll see Q3 growth probably be a little bit lighter than we saw in Q2 just due to timing. So it's really not anything more than that. Speaker 300:19:12And as a reminder, we don't have a ton of seasonality, but Q3 is typically our lowest revenue quarter, which does have a little bit impact Q2 to Q3. Speaker 400:19:26Got it. That's helpful. And then maybe just for my second one, I'll ask a follow-up on Onex. Maybe can you break out unit growth versus ASP and then talk about pricing in that line item? Obviously, you continue to take shares. Speaker 400:19:38There are still additional opportunity to raise price in the On X portfolio? Speaker 200:19:43Yes. We don't really break out the price volume. It's not something we typically do. What I can tell you is 15% growth of our Mechanical Valves segment is we continue I think in the last 6 or 7 years, we've grown this business on average of around 15% over the last I think since we acquired the company. We still have a lot of opportunity internationally, and we're still taking share in the U. Speaker 200:20:11S. Even from our high share position. We're also increasing price. I mean, our recent post approval data that came out shows an 85% reduction in major bleeding, which moves it a lot closer to a bioprosthetic valve. We're also seeing recent data that's come out on mechanical versus bioprosthetic data that's very compelling for people moving to the On X valve in patients under 70. Speaker 200:20:39So we're very bullish on what we have and we feel like we've got the best valve and we're going to keep taking share. Speaker 400:20:48Got it. Thanks for taking the questions. Congrats again. Speaker 500:20:51Thanks Frank. Operator00:20:54Our next question comes from Suraj Kalia with Oppenheimer. Please proceed with your question. Speaker 500:21:00Hey, Pat, Lance, can you hear me all right? Speaker 200:21:03Yes, we can hear you fine, Suraj. Speaker 500:21:05Congrats on all the progress. So Pat, just keying off from the last comment you made to the previous question. Can you I believe last quarter, On X was about 30% OUS share, 50% plus U. S. Yes. Speaker 500:21:24Can you give us some color as to where we are exiting Q2? Speaker 200:21:30Yes. So what I will tell you without getting into the granularity is, we're growing both markets double digits. As I just said, we've got your share comments are pretty accurate, right? We've got about a 30% global. And when you break that down, it's like over 50% in the U. Speaker 200:21:48S. And 20%, 25% internationally. So we clearly have more opportunity internationally. But I think the big story on On X is really all the dynamics that are going on. On. Speaker 200:22:04Frankly, it's our aortic valve portfolio in patients under 65. Our ROS, our pulmonary valve for the ROS, we have the only Synagraft valve for that. It's growing double digits consistently On X is growing consistently double digits with our new post approval data. As you well know, you're very well read on the data. It's a dynamic market, but there's kind of more and more negative data coming out on TAVR in patients under 65, on bioprosthetic in patients under 65. Speaker 200:22:34The difference in reoperation and mortality out to 15 years benefits mechanical valves. And they've seen lots of reoperations in patients getting TAVR under 65. And I think that's a real problem, right? I mean, there's a difference in reauthor mortality at 15 years. These are 65 year olds. Speaker 200:22:53That's a big deal. So again, I think we've got a great story with the On X valve. We're just going to keep telling our story. Speaker 500:23:01Got it. Pat, I'm drawing the blank here, so please forgive me. On neXus, remind me, when you talk about chronic aortic dissection, right, in the need and the 600,000,000 TAM, I get that. The enrollment in the trial, again, if memory serves me correctly, it's like 5, 6 patients per quarter. Is that by design? Speaker 500:23:27Is that due to patient selection? Just kind of help us understand, take a leap from here from the trial enrollment to if you'll acquire and understand how Nexus layout and whatnot in commercial adoption, how should we think about the speed of adoption? Speaker 200:23:49Yes. So I would say there's a lot in that. I think both in both of our messages Lance and I commented on, we're making an investment in the future of aortic technology. Patients today who have to have a chronic dissection repaired and we have technology for that, you're looking at a 7 to 10 day ICU stay. We have patients in Europe that are getting the Nexus device that are standing out in front of the hospital the next day, right? Speaker 200:24:16So it's a big deal. But like any new technology, there's going to be an evolution, right? So what we're talking about right now is a single branch into the annominate. That's the U. S. Speaker 200:24:26ID trial called TRIONF. We've enrolled 50 out of 60. We should enroll that by the end of the year. I think that will have modest uptake when we launch it, but we'll be looking to start a 2 branch trial probably right after that. And we think that that technology can capture half the chronic dissections in the world. Speaker 200:24:45So it's a big deal and we're very interested in the space and which is why we recut the deal. The data has been excellent and the trial is almost done. So yes, we're very excited and look forward to having it report out. Speaker 500:24:59Got it. Pat, final question, I'll hop back in queue. In terms of your sales reps, walk us through how does the bell curve look for sales rep productivity? At this stage in Artifion's evolution, are we at that point in terms of higher elasticity to sales rep commission structure? Just kind of put this thing together, how you're seeing the direct force, the sales force, U. Speaker 500:25:29S. Versus OUS? Gentlemen, thank you for taking my questions. Speaker 200:25:32Yes. Thanks, Raj. So to me, I think this is one of the real benefits you're seeing and how we can grow top line 10% and bottom line 35%. We've got an excellent sales force. You talked about here in the U. Speaker 200:25:44S. As well as in Europe and some of the international markets. Most of our reps in the U. S. Have 10 years with the company. Speaker 200:25:52They know their customers. They call on them for ROS procedures with Synagraft. They call on them with On X for aortic procedure. They call them with BioGlue. When we get ANDS approved, they will call on them for that. Speaker 200:26:03And when we get our frozen elephant trunk approved, they'll call on them for that. So the cardiac surgery segment is a much different segment than many of the other kind of medtech spaces. You don't have to scale your sales force kind of 1 to 1 with your revenue. And you see that in our leverage. So we're very excited about bringing our AMDS when it gets approved in late 2025. Speaker 200:26:27But we can just drop it in our existing reps' bags and see a lot of that incremental profitability go right to the bottom line, which has been part of our story all along. Operator00:26:47Our next question comes from Rick Wise with Stifel. Please proceed with your question. Speaker 600:26:52Hi, Pat. Hi, Lance. This is John on for Rick today. Another strong quarter in this 2Q. Just wanted to sort of look ahead, think about the bigger picture. Speaker 600:27:02You've provided guidance or a rough structure at your 2022 Analyst Day and 2025 plus but just thinking about the new approvals potentially coming through, the new potential products you're adding to the portfolio and the areas where you're innovating, just wanted to get your sense on the longer term bigger picture looking hedge. Should we expect more of the same sort of double digit growth 2025 plus? Speaker 300:27:30Yes. So we've stayed away from kind of re upping long term guidance. We're just now finishing we gave some formal targets back in 2022 through 2024. So hadn't quite finished those out yet. So we're not sending out some new ones. Speaker 300:27:47But I think we feel good about saying like, look, if you think about us looking further out with the portfolio we have now and then the things in our pipeline, we should be able to be a consistent double digit grower for an extended period of time. And then really we ought to be able to drive a lot of leverage off that. So we ought to be able to grow the bottom line really at least 2x the top line. I mean if you look this year our guidance is 3x the top line at the midpoint and we're not committing to that forever going forward. But there's a lot of leverage opportunity in the business. Speaker 300:28:25And our core business is very defendable. You've got PMA based products in markets with not a lot of competition that are really unlikely to see new entrants. And then we have this amazing pipeline. So at a high level, we feel comfortable about double digit growth and growing the bottom line at least 2x that. Speaker 600:28:47Got it. Now I appreciate the color. And just as I look to the rest of the year, I realized last year, maybe in the second quarter, you guys put through a price increase. Just wanted to think about that in 2024, 2025. Is there another opportunity for Artivion to potentially take price? Speaker 600:29:08Or are you all done for a bit? Speaker 200:29:12Yes. I've talked about this on previous calls. I mean, we look at the portfolio. We look at how differentiated our product line is. And in some cases, we have significant clinical outcomes where we spent 1,000,000 of dollars generating the data that nobody else has. Speaker 200:29:29And Synagraft Pulmonary Valve is the perfect poster for that. We spent $1,000,000 developing the technology, patenting it and getting the clinical data that now has 25 year results, which is the best valve operation for, I would say, a patient under 55 years old. For something like that, we're going to charge a premium price for it because it's it warrants. I talked about Onyx. We just invested 1,000,000 of dollars in the post approval trial. Speaker 200:29:57And we came out with data that nobody else can match. And I think that that clinical data warrants a higher price. So we're not going to go through kind of every line item on the portfolio, but you can get a sense of the things that are highly differentiated backed by patents, backed by compelling clinical data, we will charge what we think is a fair price for those. Speaker 600:30:22I appreciate the color. Thanks for taking the questions. Operator00:30:38Our next question comes from Jeffrey Cohen with Ladenburg Thalmann. Please proceed with your question. Speaker 700:30:45Hey, Pat and Lance. How are you? Speaker 200:30:47Hey, Jeff. Speaker 700:30:48Thanks for taking our questions in advance. Just a few from our end. I heard Lance, a call out on Baxter and the other revenue line. Are there any puts and takes there on Pericloud? Or do you have any clarity or see through in how things are going on their side? Speaker 300:31:06Yes. I mean, I guess, first of all, at a high level, I mean, it's not really very meaningful to us. So I mean, it's tiny to Baxter. Just to put it in context, the only reason we brought it up is it just sticks out because the decline was so significant. And I mean our visibility is not great to underlying sales, but our understanding is they're continuing to ramp up. Speaker 300:31:33And this is just some basic managing the balance sheet on their side and doing being good about inventory management is creating some fluctuation in what's a very small line item, so it just jumps off the page. So in general, we're not going to talk about Baxter's business. That's their business. But again, I would just say it's not meaningful to us, so it's really not meaningful to them. Speaker 700:31:57Got it. Okay. And then secondly, could you talk about Baguio a little bit? It looked extremely strong for the Q2 coming into $18.55 So any commentary there or any outlook as far as the back half of the year or general commentary on the strength or specific geographies? Speaker 200:32:17Yes. I think that we mentioned Lance mentioned it in his comments, right? I mean, BioGlue grew like 1% in the Q1 and it grew 12% in the Q2. Don't plug 12% in your model because it's a very kind of lumpy business. We have a lot of indirect. Speaker 200:32:33We sell in 110 countries around the world. So you can the phasing of every 90 days, you get some bigger in some quarters, less in other quarters. But on average, we think that that product line is going to grow kind of in the mid single digit. So obviously, we had a very good quarter this quarter and it's obviously extremely Speaker 700:32:53profitable. Got it. And then lastly for us, could you talk a little bit about the aortextent graft portfolio for the quarter, areas of weakness or strength or any specific SKUs or items which are doing well or not as Speaker 200:33:09well? Yes. We don't break. I mean, we made a move, I think a couple of years ago to kind of put these large buckets in place. I can tell you the area that we focus on, which is the highly differentiated, faster growing, higher margin stent graft segment, we're growing double digits in every category. Speaker 200:33:28I'm not going to break out line items and give competitors roadmaps. So we're doing extremely well. Frankly, even in the non differentiated, the more competitive stuff, we're growing double digits. So the whole portfolio is doing really well. Speaker 700:33:44Perfect. That does it for us. Thanks for taking our questions. Nice quarter. Speaker 200:33:47Thanks, Jeff. Operator00:33:50Mr. Mackin, there are no further questions at this time. I'd like to turn the floor back over to management for closing comments. Speaker 200:33:57Yeah. Well, thanks for joining. Again, we are excited about the quarter and thanks for joining the call. We've obviously got a lot of great opportunity in front of us. As you heard both Lance and I talk, we're executing well. Speaker 200:34:08We're growing 10% top line and 35% on the bottom line. Again, this year, we did it last year. We just talked about our kind of we're not giving guidance, but we think we can grow double digits top line and twice that on the bottom line. We've got an exciting pipeline, a great channel, a great portfolio, highly differentiated and we're very excited about building this aorta company and treating and taking care of more patients so our surgeons have what they need from a technology standpoint. So thanks for joining. Operator00:34:40This concludes today's conference. You may disconnect your lines at this time and we thank you for your participation.Read morePowered by