Waters Q4 2024 Earnings Report

Waters EPS Results

• Actual EPS: $4.10
• Consensus EPS: $4.02
• Beat/Miss: Beat by +$0.08
• One Year Ago EPS: N/A

Waters Revenue Results

• Actual Revenue: N/A
• Expected Revenue: $856.87 million
• Beat/Miss: N/A
• YoY Revenue Growth: N/A

Waters Announcement Details

• Quarter: Q4 2024
• Date: 2/12/2025
• Time: Before Market Opens
• Conference Call Date: Wednesday, February 12, 2025
• Conference Call Time: 8:00AM ET

Waters (NYSE:WAT) provides analytical workflow solutions in Asia, the Americas, and Europe. It operates through two segments: Waters and TA. The company designs, manufactures, sells, and services high and ultra-performance liquid chromatography, as well as mass spectrometry (MS) technology systems and support products, including chromatography columns, other consumable products, and post-warranty service plans. It also designs, manufactures, sells, and services thermal analysis, rheometry, and calorimetry instruments; and develops and supplies software-based products that interface with its instruments, as well as other manufacturers' instruments. In addition, the company offers MS technology instruments are used in drug discovery and development comprising clinical trial testing, the analysis of proteins in disease processes, nutritional safety analysis, and environmental testing. Further, the company provides thermal analysis, rheometry, and calorimetry instruments for use in predicting the suitability and stability of fine chemicals, pharmaceuticals, water, polymers, metals, and viscous liquids for various industrial, consumer good, and healthcare products, as well as for life science research. Its products are used by clinical, pharmaceutical, biochemical, industrial, nutritional safety, environmental, academic, and governmental customers working in research and development, quality assurance, and other laboratory applications. The company was founded in 1958 and is headquartered in Milford, Massachusetts.

Waters Q4 2024 Earnings Call Transcript

Presentation

[Operator]

Good morning. Welcome to the Waters Corporation Fourth Quarter twenty twenty four Financial Results Conference Call. All participants will be in a listen only mode until the question and answer session begins. This call is being recorded. If you have any objections, please disconnect at this time.

[Operator]

It is now my pleasure to turn the call over to Mr. Casper Tudor, Head of Investor Relations. Please go ahead, sir.

[Caspar Tudor, Head, Investor Relations at Waters]

Thank you, Danny. Good morning, everyone, and welcome to the Waters Corporation fourth quarter earnings call. Today, I'm joined by doctor Uday Batra, Waters' president and chief executive officer, and Amol Chabal, Waters' senior vice president and chief financial officer. Before we begin, I will cover the cautionary language. In this conference call, we'll make forward looking statements regarding future events or future financial performance of the company.

[Caspar Tudor, Head, Investor Relations at Waters]

We will provide guidance regarding possible future results as well as commentary on potential market and business conditions that may impact Waters Corporation over the first quarter of twenty twenty five and full year 2025. These statements are only our present expectations, and actual events or results may differ materially. Please see the risk factors included within our Form 10 ks, our Form 10 qs, and the cautionary language included in this morning's earnings release. During today's call, we will refer to certain non GAAP financial measures. Reconciliations to the most directly comparable GAAP measures are attached to our earnings release and in the appendix of the slide presentation accompanying today's call.

[Caspar Tudor, Head, Investor Relations at Waters]

Both are available on the Investor Relations section of our website. Unless stated otherwise, references to quarterly results increasing or decreasing are in comparison to the fourth quarter of fiscal year twenty twenty three. In addition, unless stated otherwise, all year over year revenue growth rates and ranges given on today's call are on a comparable organic constant currency basis. Finally, we do not intend to update our guidance, predictions or projections except as part of a regularly scheduled earnings release or as otherwise required by law. Now I'd like to hand the call over to Udit to deliver our key remarks.

[Caspar Tudor, Head, Investor Relations at Waters]

Amor will then present a more detailed overview of our results and guidance. And then after, we'll open the phone lines for questions. Over to you, Udit.

[Udit Batra, President & Chief Executive Officer at Waters]

Thank you, Kasper, and good morning, everyone. We delivered an excellent finish to 2024 in the fourth quarter, achieving high single digit constant currency revenue growth and low teens adjusted EPS growth. In pharma, which is our largest end market, sales grew low double digits. Before diving into the details, I want to thank my colleagues at Waters for their resilience, innovative spirit and collaboration. This fuels our strong sales performance and operational achievements as we accelerate the benefits of pioneering science.

[Udit Batra, President & Chief Executive Officer at Waters]

Throughout the year, our message has remained clear and consistent. We're executing well in an analytical instruments and systems market that is beginning its recovery. The innovation in our revitalized portfolio is well aligned with customer unmet needs at a time when instruments are ripe for replacement. Our focus and leadership position in downstream, high volume life science applications has earned us a unique exposure to an exciting mix of fast growing high volume testing opportunities. This includes GLP-one testing, PFAS testing and the genetics market in India.

[Udit Batra, President & Chief Executive Officer at Waters]

Today, I'm pleased to share the latest proof points that demonstrate our favorable position right at a time when a recovery in customer CapEx spending and instrument replacement is beginning to kick into gear. I expect the strength and momentum to continue into 2025 and we will cover this later in the call. Turning now to our results. In the fourth quarter, sales grew 6.4% as reported and 8% in constant currency. Sales exceeded the high end of our guidance range as growth accelerated across all our three reported regions.

[Udit Batra, President & Chief Executive Officer at Waters]

Instruments grew 8% outpacing our expectations as LC mass pack light scattering and TA system sales each grew high single digits or better. Recurring revenues grew 9% also marking an improvement from the previous quarter with chemistry and service both up high single digits. We continue to build momentum delivering a high teens quarter over quarter revenue ramp while funnel activity remains strong. We also achieved outstanding results within our P and L. With our sustained focus on operational excellence, our non GAAP earnings per share was $4.1 reflecting 13% EPS growth.

[Udit Batra, President & Chief Executive Officer at Waters]

Excluding the impact of FX, our adjusted EPS grew 22%. On a GAAP basis, EPS was $3.88 Turning now to the full year, sales were flat as reported and in organic constant currency as our quarterly growth performance improved every quarter. Recurring revenue grew 6% once again underscoring the unique resilience of our recurring portfolio across various market conditions. With a strong EPS result in Q4, our full year non GAAP earnings per fully diluted share was $11.86 This reflects 1% growth and includes a 5% decline due to foreign exchange headwinds. On a GAAP basis, EPS was $10.71 per share.

[Udit Batra, President & Chief Executive Officer at Waters]

Breaking out our results in more detail, we saw strong broad based growth in the fourth quarter. Strength was led by our pharma and academic end markets, both of which grew double digits. In pharma, sales grew 10% led by low double digit growth in Europe and Asia and high single digit growth in The Americas. In particular, spending amongst large pharma, contract manufacturing organizations and generics customers continued to recover where our revenue is tied to high volume regulated QAQC applications. In our non pharma segments, sales grew 6% led by low double digit growth in Europe, mid single digit growth in Asia and low single digit growth in The Americas.

[Udit Batra, President & Chief Executive Officer at Waters]

We saw strong growth in the A and G segment across Asia, including China, Japan and India as well as in Europe. By geography, Europe grew 11%, Asia nine %, America six %. In China, overall sales returned to positive growth in China and was up low single digits. Altogether, these results reflect excellent momentum into the year end. I would now like to share more in-depth commentary on what drove our strong performance.

[Udit Batra, President & Chief Executive Officer at Waters]

With our commercial focus and disciplined execution, we continue to deliver impressive outcomes driving like for like pricing gains. We also capitalized on the success of our new product launches, achieved strong placement of our new flagship products that command a price premium due to their unmatched benefits in solving customer unmet needs. Within LC, Alliance IS has paved the way for smarter, more capable liquid chromatography separation that minimizes user errors. In the fourth quarter, sales more than doubled quarter over quarter. Alliance IS constituted 20% of our HPLC revenue in the fourth quarter after adoption continued to scale throughout the year.

[Udit Batra, President & Chief Executive Officer at Waters]

Within mass spec, the Zevo TQ Absolute System remained our best selling mass spectrometer with its market leading sensitivity and sustainable design. In the fourth quarter, unit sales grew 40% year over year and constituted 50% of our Tandem Quad revenue. As a reminder, Tandem Quads are the most suitable mass specs for high volume quantitative measurements in compliant settings. The Xevo TQ Absolute has been a key driver of the strong results we've achieved in PFAS testing and in clinical applications. Our PFAS revenue grew over 40% in the fourth quarter and for the year.

[Udit Batra, President & Chief Executive Officer at Waters]

PFAS testing is a 400,000,000 global market growing at 20% annually. So this represents growth at approximately twice the market for the second consecutive year. For clinical, total clinical revenue grew low teens in the quarter, driven in part by strong sales of the IVD version of the Xevo TQ Absolute. Within our chemistry consumables business, our newer column launches aimed at separating larger, more complex molecules like biologics and novel modalities continue to perform ahead of expectations. Max Premier Columns sales grew over 30% in the quarter and over 40% for the year.

[Udit Batra, President & Chief Executive Officer at Waters]

With success of our new column launches, our exposure to higher growth, large molecule applications has risen. Large molecule applications are now approximately 40% of our pharmacochemistry revenue and growing. Our service team has continued to make strides in increasing plant attachment. For the first time, over 50% of our active installed base has a service plan in place. SDI recently recognized our service team for delivering the highest service satisfaction scores among all instrument vendors.

[Udit Batra, President & Chief Executive Officer at Waters]

At the same time, our net promoter scores lead the industry according to technology and services industry associations. During the quarter, our unique exposure to new high volume testing drivers also contributed to our growth. This includes novel therapeutic areas such as GLP-one testing, PFAS testing applications in food and environmental testing and the expanding generic drug market generics drug market in India. All three represent a compelling growth opportunity for Waters based on our leadership position in downstream high volume life science applications. In 2024, we performed very well against our growth expectations in each of these areas.

[Udit Batra, President & Chief Executive Officer at Waters]

In the near to mid term, we continue to expect 30 basis points annual average growth accretion from both GLP-one testing and PFAS testing while India is expected to add 70 to 100 basis points to the growth. Now I will talk more about our operational performance. Our team faced numerous margin challenges throughout the year, including FX, inflation and the normalization of annual incentive compensation. Despite a rapid strengthening of the U. S.

[Udit Batra, President & Chief Executive Officer at Waters]

Dollar during the fourth quarter, our unwavering focus on operational excellence allowed us to counteract the currency headwinds. We achieved a 60 basis point increase in adjusted operating margin to 35.5% after absorbing two twenty basis points of FX impact. Offsetting currency and macroeconomic headwinds is something our team has gotten very good at. For the full year, we achieved year over year adjusted operating margin expansion closing the year at 31%. This is after absorbing 130 basis points of FX related impact.

[Udit Batra, President & Chief Executive Officer at Waters]

As we look ahead, while no two macroeconomic environments are the same, instrument down cycles have historically been followed by an up cycle as a new instrument replacement cycle emerges. During these uptrends, instrument growth has typically been 2% to 3% higher than the long term average of 5%. Currently, our instrument growth sits at 2% on a five year CAGR basis versus 2019. This comes after weak macroeconomic conditions put temporary constraints on customer CapEx spending for downstream instrumentation in recent years. The growth catch up opportunity from this deferred instrument replacement is beginning to kick into gear.

[Udit Batra, President & Chief Executive Officer at Waters]

Meanwhile, in the longer term, we expect the average growth rate of instruments to actually trend higher than the historical five percent, driven by higher volume trends, new application areas like large molecules and better pricing dynamics. Together with the progress we've made in our high growth adjacencies, Waters is well positioned for an exciting new era of growth as the analytical instrument market continues to recover. This also coincides with the launch of a new wave of commercial and value creation initiatives that we look forward to discussing in detail at our upcoming Investor Day. I will now cover the twenty twenty five full year guidance. Customer spending has shown steady signs of recovery in analytical instruments, particularly in the downstream high volume settings that we serve.

[Udit Batra, President & Chief Executive Officer at Waters]

We expect these positive trends to continue into 2025. Our team continues to execute well with our revitalized portfolio at a time when instrument replacement is beginning to pick up. Together, our resilient recurring revenue growth and the ongoing impact of our idiosyncratic growth drivers we anticipate continuing our strong momentum into 2025. These dynamics support full year 2025 constant currency sales growth guidance of 4.5% to 7%. Within the P and L, the recent strengthening of the U.

[Udit Batra, President & Chief Executive Officer at Waters]

S. Dollar introduced additional foreign exchange headwinds. Nevertheless, we plan to counterbalance these impacts with robust operational performance, sustaining our margin expansion trends into 2025. This translates to a full year 2025 earnings per fully diluted share guidance of $12.7 to $13 on a non GAAP basis. This is a 7% to 10% growth versus our 2024 and includes an estimated headwind of approximately 4% due to unfavorable foreign exchange.

[Udit Batra, President & Chief Executive Officer at Waters]

Now I will pass the call over to Amol to cover our financial results in more detail and provide further details on our guidance. Amol?

[Amol Chaubal, Senior VP & CFO at Waters]

Thank you, Udit, and good morning, everyone. In the fourth quarter, we delivered a strong finish to the year. Sales of $873,000,000 grew 6% as reported and 8% in constant currency as both instruments and recurring revenues grew high single digits. With our strong commercial execution and new product portfolio, we benefited from budget flush as overall sales ramped up $132,000,000 or 18% quarter over quarter. This was meaningfully higher than the mid teens ramp assumption in our guidance.

[Amol Chaubal, Senior VP & CFO at Waters]

In constant currency terms, by end market, pharma grew 10%, industrial grew 2% and academic and government grew 16%. In pharma, sales grew 12% in Asia, 10 Percent in Europe and 9% in Americas. Instrument sales grew high single digits led by liquid chromatography as deferred customer spending continued its early stages of recovery. In industrial growth was led by our TA division, which also grew high single digits amid strength in batteries, advanced materials and chemical testing. Within our Waters division, we continued to see strong growth in PFAS related applications, which grew over 40% in the quarter.

[Amol Chaubal, Senior VP & CFO at Waters]

In academic and government, the strong performance was driven by 35% growth in Asia and 20% growth in Europe. Within Asia growth was broad based. By geography, each of our three reported regions saw significant growth acceleration versus the prior quarter. Europe grew 11%, Asia grew 9% and Americas grew 6%, each with broad strength across our end markets. In China, sales returned to growth, up low single digits.

[Amol Chaubal, Senior VP & CFO at Waters]

By products and services, instruments grew 8%, reflecting broad strength across our instrument portfolio, including LC, mass spec, light scattering and TA. In recurring revenue, chemistry grew 7% and service grew 9% as customer activity remained strong with high utilization of our installed base. Our robust growth has been supported by our commercial initiatives in areas such as service plan attachment, e commerce adoption and launch of our new bio separation columns. Turning now to full year results, sales of $2,960,000,000 were flat as reported and flat in organic constant currency terms. By end market, pharma grew 1%, industrial was flat and academic and government declined 7%.

[Amol Chaubal, Senior VP & CFO at Waters]

By geography, Europe grew 2%, while Americas and Asia both declined 1%. Asia ex China grew high single digits, while China declined low double digits as expected. By products and services, instrument growth rates recovered throughout the year and declined 7% overall. Recurring revenues grew 6% reflecting the resilience of our chemistry consumables and service businesses. Now I will comment on our fourth quarter and full year non GAAP financial performance versus last year.

[Amol Chaubal, Senior VP & CFO at Waters]

During the fourth quarter, the U. S. Dollar strengthened significantly With our focus on operational excellence, including pricing, productivity and cost management, we were able to offset the impact. Gross margin was 60.1% for the quarter and 59.4% for the full year. Excluding FX, gross margin expanded 60 basis points and 80 basis points respectively.

[Amol Chaubal, Senior VP & CFO at Waters]

For the quarter, adjusted operating margin expanded 60 basis points to 35.5%. For the full year, adjusted operating margin expanded to 31% after absorbing 130 basis points of adverse FX impact as well as the normalization of annual incentive compensation. As we look ahead, we are well positioned to continue our margin expansion journey through our productivity initiatives and take our profitability to new heights. Together with better than expected sales volume, our strong operational performance drove 13% growth in non GAAP earnings per fully diluted share to $4.1 This landed at the high end of our guidance range even with an FX headwind that was $0.23 greater than anticipated. On GAAP basis, EPS was $3.88 For the full year, non GAAP EPS grew 1% to $11.86 This includes a decline of approximately 5% due to foreign exchange headwinds.

[Amol Chaubal, Senior VP & CFO at Waters]

On a GAAP basis, EPS was $10.71 Our effective adjusted operating tax rate was 16.9% for the quarter and 16.4% for the full year. Our average share count was 59,600,000.0 for the quarter and for the full year. Turning now to free cash flow capital deployment on our balance sheet. We define free cash flow as cash from operations, less capital expenditures and exclude special items. In the fourth quarter of twenty twenty four, free cash flow was $188,000,000 after funding $52,000,000 of capital expenditures, including the purchase of $13,000,000 manufacturing facility in Colorado.

[Amol Chaubal, Senior VP & CFO at Waters]

For the full year, free cash flow was $744,000,000 or 25% of sales, resulting in a free cash flow to adjusted net income conversion ratio of 105%. With the strong free cash flow generation in our business model, we've made solid progress delivering our balance sheet and our net debt position is now approaching pre wired acquisition levels. In the fourth quarter, we reduced debt by approximately $200,000,000 resulting in approximately $900,000,000 of debt repayments made in 2024. At the end of the quarter, our net debt position was approximately $1,300,000,000 dollars which is net debt to EBITDA ratio of about 1.3 times. We maintain a strong balance sheet, access to liquidity and a well structured debt maturity profile.

[Amol Chaubal, Senior VP & CFO at Waters]

This trend allows us to prioritize investing in growth. We continue to evaluate M and A opportunities that will enhance value creation for our shareholders. We'll also evaluate the resumption of our share repurchase program during the course of 2025. Now I would like to share further commentary on our 2025 outlook. Customer spending has shown steady signs of recovery in analytical instruments, particularly in downstream high volume settings that we serve.

[Amol Chaubal, Senior VP & CFO at Waters]

We expect these positive trends to continue into 2025. Our team is executing very well with our revitalized portfolio. Together with our resilient recurring revenue growth and supported by our ongoing impact of our idiosyncratic growth drivers, we anticipate achieving strong results again in 2025. These dynamics support full year 2025 constant currency sales growth guidance of 4.5% to 7%. At current exchange rates, currency translation is expected to result in a negative impact of 2% on full year sales.

[Amol Chaubal, Senior VP & CFO at Waters]

Therefore, our total reported sales growth guidance is approximately 2.5% to 5%. Within the P and L, we plan to counterbalance the impact of foreign exchange headwinds through continued robust operational performance, sustaining our strong margin performance into 2025. We expect to deliver a gross margin of 59.6% and an adjusted operating margin of 31.2% for the full year. In both cases, this represents 20 basis points of net year over year expansion, net of 40 basis points of FX headwind. We expect our full year net interest expense to be approximately $46,000,000 Our full year tax rate is expected to be largely consistent with 2024 levels at 16.5% as we anticipate mitigating the incremental effects of Pillar two, including those relating to Singapore.

[Amol Chaubal, Senior VP & CFO at Waters]

Our average diluted share count is expected to be approximately 59,300,000.0. Rolling all this together, on a non GAAP basis, our full year 2025 earnings per fully diluted share guidance is projected in the range of $12.7 to $13 which is approximately 7% to 10% growth and includes an estimated headwind of approximately 4% due to unfavorable foreign exchange. Looking to the first quarter of twenty twenty five, our constant currency sales growth guidance is projected in the range of 4% to 7%. At current rates, currency translation is expected to subtract approximately 3%. Therefore, our total first quarter reported sales growth guidance is 1% to 71% to 4%.

[Amol Chaubal, Senior VP & CFO at Waters]

The first quarter of twenty twenty five has two fewer days than the first quarter of twenty twenty four. At the same time, the fourth quarter of twenty twenty four had two additional days than the fourth quarter of twenty twenty three. Based on these dynamics, together with our 4% to 7% constant currency sales growth guidance and an expected seven percentage points of currency headwind on earnings, first quarter non GAAP earnings per fully diluted share is estimated to be in the range of $2.17 to $2.25 Now, I would like to turn the call back to Udit for our closing comments. Udit?

[Udit Batra, President & Chief Executive Officer at Waters]

Thank you, Amol.

[Udit Batra, President & Chief Executive Officer at Waters]

Twenty twenty four was a defining year for Waters. We delivered excellent sales and operational performance, capitalized on the momentum of our new product launches and saw strong contribution from our idiosyncratic growth drivers. We also made continued progress in our high growth adjacencies. As we look to 2025, there is a lot to be excited about. We're coming out of the gate stronger than ever in market conditions that are beginning to recover.

[Udit Batra, President & Chief Executive Officer at Waters]

We are confident in our ability to deliver enhanced value for our shareholders. With that, I will turn the call back over to Casper.

[Caspar Tudor, Head, Investor Relations at Waters]

Thanks, Sudha. That concludes our formal comments. Danny, we are now ready to open the phone lines for questions.

[Operator]

We will now begin the Q and A. Our first question comes from Syco Peterson at Jefferies. You may now unmute your line and ask your question.

[Tycho Peterson, Managing Director at Jefferies Financial Group]

Alright. Sycho Peterson. Hey. So, Uday, I'm wondering if you could talk a little more just on, you know, a couple of things. One, budget flush dynamics, you know, to what degree you thought, you know, you had pulled forward here with the new administration and quantify any budget flush impact.

[Tycho Peterson, Managing Director at Jefferies Financial Group]

And then on replacement cycle, just talk a little bit about where we are in the process. You know, you've talked in the past about customers bringing IT and procurement to the table. You know, how widespread is it among your pharma customer base? And and where do you think you go in terms of, you know, IS mix, by the end of the year? I know you talked to it was 2020% in the fourth quarter.

[Tycho Peterson, Managing Director at Jefferies Financial Group]

And then the follow-up is just capital allocation. You know, you you're down to 1.3 turns leverage. What's the appetite to resume, you know, share repurchases versus look at m and a? And, you know, what's the appetite if it's the latter for larger deals? You know, what can you say about max leverage thresholds and appetite to issue stock?

[Tycho Peterson, Managing Director at Jefferies Financial Group]

Thanks.

[Udit Batra, President & Chief Executive Officer at Waters]

Sweet. Thank you, Tycho, and good morning. Good morning again. Look, firstly, on the budget flush, 2024 was really almost a typical year. We saw a high teens ramp from Q3 to Q4, and that was helped by the sales momentum that we saw at the end of the year.

[Udit Batra, President & Chief Executive Officer at Waters]

So rather a typical budget flush, if you want to call it that. Now to your question on the replacement cycle. Look, we finished the year extremely strong, right, so high single digit of instrument growth. And LC, as you mentioned, Alliance IS is now 20% of our HPLC sales. Really, really solid performance.

[Udit Batra, President & Chief Executive Officer at Waters]

Pharma grew double digits to finish the year and driven by large pharma where the replacement cycle has begun and the conversations, as I mentioned in the last quarter, are now quite widespread. So, the double digit growth in pharma, in the pharma segment driven by large pharma, initiating replacement, CDMOs, which are also starting to see good momentum, and of course, continued good performance in India in the generics market. And all of it, as I mentioned earlier, is, of course, driven by our late stage focus in QAQC, in manufacturing, where instruments are tied to, instrument replacement is tied to sort of the usage. And that scales with the volume. And it's really helped in no small part due to our strong new portfolio, especially driven by Alliance IS in the HPLC space.

[Udit Batra, President & Chief Executive Officer at Waters]

So feel very good about where we stand on the instrument replacement cycle. And the funnels going into the year are very strong, so expect really no change in what we're seeing from our customers. So I'll hand over now to Amol to talk a bit about the capital allocation.

[Amol Chaubal, Senior VP & CFO at Waters]

Yeah. Look, I mean, we continue to look at assets that sort of align with our value acceleration goals. Clearly, we've said we don't mind going up to 2.5 times because we can deliver pretty quickly as you've seen with Wyeth. And we most critically, we want to be financially disciplined when we look at these targets and make sure sort of these assets are EPS accretive and create good high single digit ROIC at least by year five.

[Udit Batra, President & Chief Executive Officer at Waters]

Thank you, Amol.

[Operator]

Our next question comes from Vijay Kumar at Evercore ISI. Please unmute yourself to ask your question.

[Vijay Kumar, Senior Managing Director at Evercore ISI]

Hi, Udit. Good morning and, thank you for taking my question. Congrats on a really nice print here. But maybe before I get to my questions, I just want to have, maybe a small clarification. I would characterize Tycho as a our friendly, crazy sinus.

[Vijay Kumar, Senior Managing Director at Evercore ISI]

I think it has a better ring to it. So, there you go, Tycho. I I guess, a few, Udet on on the guidance here. This this four and a half to seven, it's it's it's best in class so far, right, relative to tools, some of your peers. How are you incorporating some of the macro related risks, you know, when they think about tariffs, perhaps NIH, you know, spending cuts, perhaps potential cuts to agencies like EPA.

[Vijay Kumar, Senior Managing Director at Evercore ISI]

I'm just curious on how, that was baked into the guidance and I had one follow-up.

[Udit Batra, President & Chief Executive Officer at Waters]

Sure. So, thanks. Thanks Vijay. I think as you start talking about sort of Tycho, I should also say and I forgot to say it in the prepared remarks, go Eagles. We're big Eagles fans here, so just wanted to insert that before answering your question.

[Udit Batra, President & Chief Executive Officer at Waters]

On the guidance itself, look, we finished the year with high single digit growth, right? And we saw strength in pharma, double digit growth in pharma. We saw strength in A and G. New products with the Alliance IS now almost 20% of the total revenue in Q4 for HPLC Zivo TQ Absolute now almost 50% of the total revenue in quantitative mass spec. New products are doing extremely well, and they're serving these idiosyncratic growth drivers, GLP-1s, PFAS testing, the India generics market.

[Udit Batra, President & Chief Executive Officer at Waters]

So it's a very good setup as we go into 2025. We expect the same sort of trends to continue. Now, if you just look at the guidance, it's 4.5% to 7%. Recurring revenues have grown six percent to 7% through all sorts of macro cycles, right? So there's not much more evidence required there on what's going to happen there.

[Udit Batra, President & Chief Executive Officer at Waters]

So let's assume that that's the higher end of the guidance. Then instruments need to grow roughly 4.5% for us to get to the midpoint of the guidance. Finishing the year of instruments at high single digits with the replacement cycle really beginning in earnest across large pharma, where we see really good strength, funnels are very strong. I spent some time with our sales team across the globe as sales meetings are ongoing. And there's a lot of excitement with our new portfolio.

[Udit Batra, President & Chief Executive Officer at Waters]

There's a lot of excitement in the discussions that are taking place, especially with large pharma and the CDMOs. So feel very good about what we see in the funnels. New products are gaining traction. So same sort of trends are moving into 2024. And there is no reason why we should not be able to meet and exceed the lower end of the guide with all the positive trends that we're seeing.

[Udit Batra, President & Chief Executive Officer at Waters]

So we've built a bit of prudence on the lower end of the guide at 4.5%. And we will start to get more constructive, as the year progresses. So I hope that gives you some flavor of what we're thinking about, in the full year. So 4.5% in the lower end sort of measures has some measure of prudence. And as we see any sort of headwinds, we should be able to more than combat it and meet the guidance.

[Vijay Kumar, Senior Managing Director at Evercore ISI]

That's helpful, Odette. And maybe one follow-up on on, you know, when you think about the components of guidance, PFAS, GLP one, are we still assuming, you know, 30 basis points of contribution? How are you thinking about China, India within that guidance framework and pricing contribution?

[Udit Batra, President & Chief Executive Officer at Waters]

Yeah. A big a big question. Let me let me try to let me try to address the idiosyncratic pieces, the GLP one and PFAS. First, GLP-one's, I mean, we're going from strength to strength. As you know, we have 100% of our column, 100% share in the columns, usage.

[Udit Batra, President & Chief Executive Officer at Waters]

We have a significant share in instrument usage. And we are the number one player in online testing for, GLP-one. So we do expect the 30 basis points to continue. We have good line of sight on it. PFAS testing, we finished the year with 60 basis points of contribution to the overall growth.

[Udit Batra, President & Chief Executive Officer at Waters]

But we're assuming for, in the 2025 guidance, a 30 basis points accretion. So both of them are 30 plus 30. And India, has contributed over 100 basis points in 2024, finishing the year, finishing Q4 at over 30% growth. Right? For the full year, India on a constant currency basis was over 25 growth.

[Udit Batra, President & Chief Executive Officer at Waters]

Right? So we've assumed India will be at least 70 to 100 basis points accretive to the growth going forward. China, we've sort of maintained our low single digit posture there, right? So China, Q4, came in as expected. Low single digit growth, modest contribution from stimulus.

[Udit Batra, President & Chief Executive Officer at Waters]

We expect the same, in 2025. So China could, as the stimulus comes in, could give us a bit of an upside.

[Amol Chaubal, Senior VP & CFO at Waters]

And the last one on pricing, closer to 200 basis points.

[Operator]

Our next question comes from Puneet Souda at Leerink. Please unmute your line and ask your question.

[Puneet Souda, Senior MD at Leerink Partners]

Yeah. Hi, Luna. Thanks for the questions here. So, first one, just wanted to touch on the first quarter guide, 4% to 7%, a little bit wider than historical pattern. Just want to clarify, I know you talked about the full year guide, but just, you know, given the recent NIH cuts and potential for academic freezing there and instrumentation in the near term, sort of just help us understand how are you baking that in for The US academic side And how should we think about the 4% versus the 7%?

[Puneet Souda, Senior MD at Leerink Partners]

I mean, the dynamics that need to play out in the quarter already we are in Q1. So I'm sure you've thought about, you know, before setting the guide as to on the lower end versus the higher end, if you could elaborate a bit.

[Amol Chaubal, Senior VP & CFO at Waters]

Yeah. So look, I mean, in Q4, we grew 8% constant currency. Keep in mind, Q4 benefited by two extra days, which is roughly 1% extra growth. And then Q1 this year has two less days. So you know sort of has the reverse dynamics.

[Amol Chaubal, Senior VP & CFO at Waters]

So net net where we are guiding at the midpoint roughly is in line with how we performed in Q4 due to the day's impact, right? Now the guidance range is slightly larger than usual, which as you can appreciate given all the uncertainties sort of that overhang the situation. And with Q1 being our smallest quarter, we've given ourselves some prudence and cushion in situation where some of these uncertainties were to materialize. And if they do materialize, we end up at the lower end of the guidance. If they don't, we end up at the higher end of our guidance.

[Amol Chaubal, Senior VP & CFO at Waters]

And that's on the sales side. And then keep in mind, I mean, dollars trended so significantly, through the course of Q4, it now creates a 7% earnings headwind in Q1. And so when you grow 4% to 7% and have a 7% FX headwind on earnings, you're sort of at EPS that's flat or slightly better than flat and that's where the EPS guide is.

[Udit Batra, President & Chief Executive Officer at Waters]

And maybe just to embellish a little bit on EPS in Q1, Puneet. I mean, as I mentioned earlier, I mean, this is the time for growth for Waters. We're seeing incredible growth across our key customer segments. Our sales meetings are back, and we want to invest, invest in training our folks. People are very excited about the traction the new products are gaining.

[Udit Batra, President & Chief Executive Officer at Waters]

They're very excited about the chemistry piece, and we're investing in ensuring that our folks are trained, our sales teams are trained. So we're continuing to invest, even in Q1. And Q1 is, again, as I mentioned, is the smallest quarter. So the sales meetings are back. And we're basically investing for growth, starting already in Q1.

[Puneet Souda, Senior MD at Leerink Partners]

Got it. That's helpful. And then if I could double click on both Europe and India. Europe, if you could just elaborate some of the dynamics there, budget flush, pharma versus non pharma. And then also, specifically on India, Udit, I would love to get your thoughts on 70 to 100 bps contribution against strong throughout 2024.

[Puneet Souda, Senior MD at Leerink Partners]

How do you, how are you, India team and yourself, how are you thinking about the paddle cliff opportunity here? And how should we think about that opportunity getting layered into the growth algorithm over the next few years?

[Udit Batra, President & Chief Executive Officer at Waters]

Yeah. Let me let me start with India and then we'll we'll do Europe Second. Very pleased with both of those end markets. But looking at India, like I said, India of Q4 was 34% constant currency growth, and for the year, 27%. India is now a meaningful contributor to waters, at over 8% of our total sales.

[Udit Batra, President & Chief Executive Officer at Waters]

So really feel good about what the team's been doing on the ground. We are the market share leader in the key generics companies in India and our columns, our instruments are used there. Alliance IS is also doing well. We have the highest service attachment rate there. So really feel good about what we're doing on the ground from an execution standpoint.

[Udit Batra, President & Chief Executive Officer at Waters]

Looking ahead, the genericization opportunity is very significant, right? So $240,000,000,000 of revenues will go off patent over the next five to seven years. India continues to supply roughly 50% of the global genetics market. And over half of that $2.42 50,000,000,000 is a small molecule. So that fits right into the current business model that exists.

[Udit Batra, President & Chief Executive Officer at Waters]

And half of it is biosimilars, which is now developing in many of these markets. So feel good about the opportunity going forward. And just to give you a case in point, semaglutide genericization is expected to hit sometime in 2026. And the top generics players are already working with us to adapt and adopt the processes that the key innovators have been using. Amol, you want to start with Europe?

[Amol Chaubal, Senior VP & CFO at Waters]

Yeah. I mean, look, Europe is executing super well, right? 11% growth. It's across the board. Double digit growth in pharma, high single digit growth in industrial, double digit plus growth in A and G, instruments growing high single digit plus.

[Amol Chaubal, Senior VP & CFO at Waters]

So between how our teams are executing together with the refreshed portfolio together with some of the idiosyncratic growth opportunities like PFAS and GLP 1s, the team is capitalizing really well in what's out there.

[Udit Batra, President & Chief Executive Officer at Waters]

Yes. And I mean, just to sort of build on that, Europe is I mean, Europe's been doing extremely well for the full year and finished the year extremely strong. The academic segment, at the end of the year usually sees a significant budget flush, and we did. And as I mentioned earlier to Tycho's question, look, I mean, 2024 was a typical year for us, right, with a budget flush sort of going back to what we've seen in historic times. So really good finish to the year in Europe and very, very excited about how the year has started there with good conversations across different customer segments.

[Operator]

Our next question comes from Eve Bernstein at Bernstein. Please unmute your line and ask your question.

[Eve Burstein, US Life Science Tools and Diagnostics Analyst at Bernstein]

Great. Good morning. Thanks so much for taking my question. We talked a lot about the replacement cycle, and, kind of the the pent up opportunity from 2019 to 2024. But at a conference in January, you said that the instrument replacement commercial initiative was progressing well with still 15% of lagged 2015 to 2019 replacement opportunity remaining.

[Eve Burstein, US Life Science Tools and Diagnostics Analyst at Bernstein]

So how does that number compare to average, versus when you're coming out of a down cycle and starting an up cycle? Essentially, you know, is that better better or worse? And how much of that replacement opportunity is in China specifically?

[Udit Batra, President & Chief Executive Officer at Waters]

So it's a good question, Neev, and thanks for paying specific attention to those separate drivers. So just to sort of clarify for everyone, there are two different instrument growth drivers. One is the pent up demand for replacement where there was deferred replacement that took place in the 2023, '20 '20 '4 timeframe and replacements were deferred from that timeframe to a bit later. So that's what we're calling the replacement cycle. That is a standard cycle that occurs in the industry.

[Udit Batra, President & Chief Executive Officer at Waters]

And during that time, we see a 2% to 3% outperformance in instrument growth rate versus the 5% average over the long term, Right? So that's what we're calling the replacement cycle. The signs of that are rather clear when you talk to customers because the meetings that take place are with a larger number of people. They're planning a multi year replacement. Procurement sits in that discussion.

[Udit Batra, President & Chief Executive Officer at Waters]

IT sits in that discussion. The lab managers sit in that discussion, and a whole bunch of folks from our side sit in those discussions. And those are widespread across the industry, right now. And so we're seeing very good traction on that. What you asked about is the 15% that is pending from the transformation that we began in 2020 and 2021.

[Udit Batra, President & Chief Executive Officer at Waters]

And there, you'll recall, we had said, look, there are roughly 13,000 instruments that should have been replaced in the 2018 to 'twenty timeframe that got deferred. And we worked very hard to replace them in 2021 and 2022, but the macro cycle slowed down in 2023 and 2024. And that 15% is still pending, right? So we have a database in our CRM system and we track this diligently, right? So people don't forget that that 15% is still pending.

[Udit Batra, President & Chief Executive Officer at Waters]

So you can superimpose the two. I didn't want us to now go crazy sort of with instrument growth rates. I was trying to bring the two together. But in our CRM system, we have that tracked really diligently. So I hope that clarifies the replacement question.

[Udit Batra, President & Chief Executive Officer at Waters]

On China, we've assumed a low single digit growth. I mean, market conditions have improved over the year, but we've assumed that it's still muted. There is an impact of the stimulus expected in 2025. Again, there we've been modest. We've assumed a sort of a low to sorry, mid to high single digit single mid to high single digit million contribution for the year.

[Udit Batra, President & Chief Executive Officer at Waters]

So we expect China to remain sort of at least in the guide remain the same. And if there's no stimulus and more replacement, we should see more dynamic more dynamic growth.

[Eve Burstein, US Life Science Tools and Diagnostics Analyst at Bernstein]

That's great. Thanks a lot for clarifying. One, clarification just on price. So you said in response to Vijay, pricing was closer to to 200 bps. Just to clarify, was that the contribution for growth in April?

[Eve Burstein, US Life Science Tools and Diagnostics Analyst at Bernstein]

And if so, how much does pricing contribute to the '25 guide? And are you including the effect of a double upgrade in that contribution? And how much is that?

[Amol Chaubal, Senior VP & CFO at Waters]

Yeah. So look, I mean, when we quote pricing, it's always like for like SKU, like for like geography. It does not include the benefits of the upsell. '24 was close to 200 basis points contribution and that's in line with what we have in our '25 guide.

[Operator]

Our next question is from Brandon Couillard at Wells Fargo. Brandon, please unmute your line and ask your question.

[Brandon Couillard, Managing Director at Wells Fargo]

Thank you very much. Udi, I think you talked about instrument growth this year 4%, four point five %, just curious how that compares between LC, mass spec and light scattering and any details you can kind of give us on what you've assumed in terms of growth across the three end markets?

[Udit Batra, President & Chief Executive Officer at Waters]

Yeah. I think you should presume sort of mid single digit ish for all three. So mass spec at 4%, in that 4.5% number, LC at five, TA at five and light scattering somewhere there or thereabouts also. A bit higher than that since it's accretive, probably closer to double digits, but it's such a small portion of the business. It doesn't make a huge difference at this point.

[Udit Batra, President & Chief Executive Officer at Waters]

And Brandon, even as we finish sorry, Brandon, just to clarify, even as we finish the year, all instrument segments grew at minimum high single digits. So LC, mass spec, TA and why it was well into the double digits. Got it. Go ahead.

[Brandon Couillard, Managing Director at Wells Fargo]

Got it. And your PFAS market sizing continues to walk up. Now you're talking about 400,000,000 opportunity. Prior it was kind of 300 to $3.50. What's enabling, you know, you to grow so much faster than the underlying market?

[Brandon Couillard, Managing Director at Wells Fargo]

Where is that developing most rapidly, either by application or region right now?

[Udit Batra, President & Chief Executive Officer at Waters]

Yeah, I think it's, so the market itself has significant unmet needs, right? I mean, we started with the environmental market, then it's expanded into food testing step by step. The academic customer segment also purchases instruments to quantify and assess PFAS. So very dynamic market. And you're right, the market size continues to increase as more and more applications come in.

[Udit Batra, President & Chief Executive Officer at Waters]

We've grown almost double the market growth rate, and it's driven, I mean, first by having the best in class instrument because PFAS testing, remember, is not just one molecule. It's over 40 already classified as PFAS. All of these need to be quantified and the regulators keep increasing the sensitivity requirements. And we have the most sensitive instrument in the market with the lowest environmental footprint. And that's worked extremely well in the hands of our customers, right?

[Udit Batra, President & Chief Executive Officer at Waters]

So the number one driver is the success of the Zevo TQ Absolute, and which now is in Q4 was 50% of the revenue of quantitative mass spec. So highly, highly successful launch driven not just by the differentiated differentiation but also the commercial excellence. And equally, our teams are investing a ton of energy in, in the compliant informatics segment. The Waters Connect, informatics software is doing very well in regulated settings. Remember, our history and legacy is in compliant settings where data integrity is of a premium.

[Udit Batra, President & Chief Executive Officer at Waters]

So we've taken what we've learned from Empower, adopted it into Waters Connect, and that's working very well in that, in the PFAS regulated segment. And then finally, chemistry and workflows. We continue to launch new chemistry and new workflows to really keep up with the complexity of different PFAS molecules. So across the board, and the market size is expanding largely because of application sets. So feel very good about where we sit there.

[Operator]

Our next question is from Dan Arias at Stifel.

[Dan Arias, Managing Director at Stifel Financial Corp]

Good morning guys. Thank you. Uda, can you just maybe expand on that PFAS idea a little bit? I mean, to what extent do you still see there being additional capacity needs in the lab base on the water testing side in The U. S?

[Dan Arias, Managing Director at Stifel Financial Corp]

Because I know to your point, application expansion, geographic expansion is important, but I'm just sort of trying to understand what you've done in 2024 when it comes to scaling up these labs in order to test on the water side in The U. S. Specifically.

[Udit Batra, President & Chief Executive Officer at Waters]

Yeah. So that's a good question, Dan. It's early days still, right? I mean, when you look at PFAS testing, and this is something we'll spend some time at our Investor Day as well, breaking down the different segments that have constituted growth, right? The academic segment, the first round, spent a lot of time and energy, and we had very good sales in that segment, helping people understand what the heck pFAS really is, developing methods that could get standardized, and then be disseminated second to public health laboratories, to water testing laboratories.

[Udit Batra, President & Chief Executive Officer at Waters]

And then the last piece is is, the second to last piece is water testing laboratories across, across the country. And the final one is is people who have to do remediation. So when you think of PFAS testing, it's not just contract testing labs. It's also academic labs, which started first, then it's public health labs that set standards, then it's, then it's, contract testing organizations like water testing, and then finally people who have to remediate PFAS out. So we're in the very early innings of the penetration.

[Udit Batra, President & Chief Executive Officer at Waters]

And as I said, we'll talk more about it at the Investor Day, but we're outpacing the market quite significantly.

[Dan Arias, Managing Director at Stifel Financial Corp]

Okay. Thanks for that. Maybe just on the mass spec side, I mean, to what extent do you feel like the uptake there is partly a function of or being helped by the LC replacement cycle? In other words, if you look at LC MS combo purchases now versus prior periods, what do you see and what is sort of embedded in that, that mass spec growth rate that you're talking about for this year mid single digits when it comes to just sort of, that being driven by LC uptake versus performance and new platform introductions, etcetera, if that's something that you can kind of speak to. Thanks.

[Amol Chaubal, Senior VP & CFO at Waters]

Yes. Look, I mean, that mass spec uptake is not meaningfully impacted by LC replacement. A lot of LC replacement is happening in manufacturing QAQC, where LC sort of operates largely standalone. What is helping mass spec meaningfully is various vectors that have come together based on our revitalized portfolio. As Ureth mentioned, PQ Absolute is doing exceedingly well, not just in PFAS, but across the applications in food and pharma space as well, as well as in clinical.

[Amol Chaubal, Senior VP & CFO at Waters]

You have something like BioAccord doing well in bioanalytical characterization. You have some of the newer launches on the high risk space that are catering to very specific needs and that they're doing exceedingly well on those applications. And that's why you see sort of the kind of growth you're seeing on mass spec, not driven by LC replacement.

[Udit Batra, President & Chief Executive Officer at Waters]

Yeah. So, I mean, just to elaborate on that a little bit, it's the two dimensions, right? So it's the different pieces of mass spec that are individually contributing due to innovation. So be it bFAST testing, be it mass spec usage in genotoxin purity testing in pharma, be it mass spec testing. And this is only Xevo TQ Absolute in clinical.

[Udit Batra, President & Chief Executive Officer at Waters]

And then, of course, there's the BioAccord, which is doing extremely well. And then the Xevo MRT, which is a new product, that is on the high risk side. So you see the innovation contributing. And then that has helped on the customer dimension by a strong growing segment like PFAS. It's helped to some extent by late stage development, where mass spec is significantly was used significantly for quantitative assessment of different types of biologics.

[Udit Batra, President & Chief Executive Officer at Waters]

Right? So you see that two dimensions working very well for mass spec, the innovation as well as the different customer segments and not only due to the LC replacement cycle. As Amol mentioned, that's mostly an LCUB link, for small molecules.

[Operator]

Our next question is from Matt Sykes at Goldman Sachs. Matt, please unmute your line and ask your question.

[Analyst]

Hi. This is Evian for Matt. Thanks for taking my questions. So the first one, you've seen impressive growth in services. Can you talk through the benefits of your Empower software?

[Analyst]

And then any particular applications areas where you see higher attachment rates and then any leverage you're using to improve that going forward?

[Amol Chaubal, Senior VP & CFO at Waters]

Yes, I mean, look, no two recurring revenues are equal. And our recurring portfolio proves that, right? Because even in this downturn when most other recurring portfolios have been flat or low single digits, we've been rock solid at 6% to 7% growth. And what's sort of contributing to that is our unique position with Empower coupled with how well we've done with service attachment rates, where our net promoter scores are on service, our launches in bioseparations columns, as well as the progress that we've made on our e commerce with chemistry consumables. And that's sort of what is driving this rock solid 6% to 7% recurring revenue growth.

[Analyst]

Great. And then can you talk through the strength you saw in the academic and government section this quarter? And then what your expectations are going into 2025? Any potential impact from NIH risk?

[Amol Chaubal, Senior VP & CFO at Waters]

Yes. I mean, look, Q4 was very strong from an A and G perspective. It did benefit from the typical budget flush dynamics, particularly in markets like Europe. We also saw some initial orders getting converted on stimulus in China. But again, longer term, this market has traditionally been low single digit, at best mid single digit grower.

[Amol Chaubal, Senior VP & CFO at Waters]

Right? And it's very choppy. So you can't really count on this trend. I think as we get into '25, we will benefit from the stimulus in China. But again, there are so many puts and takes there.

[Amol Chaubal, Senior VP & CFO at Waters]

So we've put a very prudent assumption in our guide. And if it plays out better, that will be an upside. We don't have much direct exposure to NIH funding, very little actually, less than one percent. So we're not exposed to that dynamics because our primary business is pharma and industrial. It's a small portion of our business, less around 10%, and we continue to monitor the dynamics.

[Udit Batra, President & Chief Executive Officer at Waters]

Yeah. And and just to sort of finish up, I mean, for 2025, we've assumed low single digit growth in A and G, right? So not the dynamism that we saw in Q4, especially in pharma. We've not assumed that at all in A and G for the for the 2025 guide. So it's a low single digit growth.

[Operator]

Our next question is from Dan Brennan at TD Cowen. Dan, please unmute your line and ask your question.

[Daniel Brennan, Managing Director at TD Cowen]

Terrific. Thank you. Thanks for the questions, guys. Maybe just the first one on instruments just for the guide. I think you said 4% for 2025.

[Daniel Brennan, Managing Director at TD Cowen]

Just confirm that. Maybe it feels a little conservative. And if you could speak to, you know, you've highlighted this five year CAGR and this 5% normalization. So where did we end up 24% and kind of what's implied on 25% and kind of any reason why the recruitment you're expecting in 25%, is that on the normal trend line or is it above or below?

[Udit Batra, President & Chief Executive Officer at Waters]

So thanks, Dan. Look, we've assumed, the 4.5 that the range is 4.5% to 7% for the full year. And just to repeat what I started with, the seven ish, 6% to 7% you should assume is what we think is the recurring revenue. And you can you can see why that is a pretty stable and rock solid assumption. Instruments need to grow 4%, four point five % for us to get to the midpoint of the guide.

[Udit Batra, President & Chief Executive Officer at Waters]

Now your question is a good one. I mean, we finished the year with high single digit growth in instruments. The funnel is extremely strong and the conversion looks extremely strong, especially led by pharma, where we're seeing very good traction of our Alliance IS instrument to sort of support the replacement cycle. We're seeing the idiosyncratic drivers contributing nicely. I think as you look at 2025, the way I would look at it is we will start to get more constructive as the year goes on.

[Udit Batra, President & Chief Executive Officer at Waters]

We will start to reveal more information because at this point we feel very optimistic. We see good funnels. Q1 is the smallest quarter. We just want to get more information before we start sort of saying, Hey, you know, it's going to be another eight percent, nine percent a year for instruments. Typically, and you're right again to point out, typically when we come out of a trough in instrument replacement, we usually see a 2% to 3% outperformance versus the long term average, which is 5%.

[Udit Batra, President & Chief Executive Officer at Waters]

Right? So going back to the CAGRs, the long term average is 5%. Usually, when you come out into the replacement cycle, you start seeing a 2% to 3% outperformance. All signs are pointing in that direction. We just want to start the year with a bit of, prudence and derisk it as the year goes on.

[Udit Batra, President & Chief Executive Officer at Waters]

Amol, anything to add?

[Amol Chaubal, Senior VP & CFO at Waters]

Yeah. Look, whichever way you look at it, area under the curve, CAGRs, average fleet life, and even if you exclude China for US and European markets, there is a meaningful catch up opportunity from each of these analytical viewpoints. Right? And we see that in the dialogue with large pharma. The dialogue with CDMOs is starting to improve.

[Amol Chaubal, Senior VP & CFO at Waters]

The one thing one has to keep in mind is not every part of our customer base is recovering to its healthy state. Right? We still have biotechs. We still have biotech research. These things haven't recovered or China Pharma hasn't recovered to a level it needs to.

[Amol Chaubal, Senior VP & CFO at Waters]

So the ramp of this replacement cycle will not be as steep as historical, but the length or the duration of this replacement cycle is likely going to be longer just because eventually all these lagging segments of the market have to come back and replace their aging instrument fleet.

[Daniel Brennan, Managing Director at TD Cowen]

Great. And then I know there was one question on India, but maybe just one follow-up since it is so strong for you right now. I think I heard you say over 25% growth in '24 over 100 basis points contribution.

[Amol Chaubal, Senior VP & CFO at Waters]

Did we lose Dan? Dan, we lost you.

[Caspar Tudor, Head, Investor Relations at Waters]

Let's proceed to our next question asker please.

[Operator]

Sure thing. Our next and final question is from Catherine Schulte at Baird. Please unmute your line and ask your question Catherine, thank you.

[Catherine Schulte, Senior Research Analyst at Baird]

Hey guys thanks for the questions, maybe just first on pharma great to see that return to double digit growth this quarter, Maybe just to go back to Tycho's questions, is there a way to quantify the stronger budget flush dynamic in the quarter and what are you assuming for pharma growth both for the first quarter and the full year?

[Udit Batra, President & Chief Executive Officer at Waters]

Yeah. So, Catherine, for the for Q4, I mean, it was, as I said, it's very strong growth. We're very happy with it. It's it really supports our late stage focus. But as you look at Q4, the ramp was typical to the pre pandemic years, right?

[Udit Batra, President & Chief Executive Officer at Waters]

So high teens, almost 20% from Q3 to Q4. So normal budget flush dynamic, not more, not less, right? So it's stronger than what we saw last year and the year before, but, starting to trend towards a normal and, to a normal, which, to a normal level, which is consistent with how pharma, late stage pharma is behaving, QA, QC spending. So we start to see a normalization of behavior there.

[Catherine Schulte, Senior Research Analyst at Baird]

And then maybe just on the services side, you mentioned over 50% of your active installed base now has a service contract in place. I believe your target is to get that to 55. So can you just talk to where you think that can go throughout the year?

[Amol Chaubal, Senior VP & CFO at Waters]

Yeah. Look, I mean, we're very happy with the progress that we've made and every year we start with a goal and we end up achieving double that goal in the year. And keep in mind, this is just based on instrument install base out there. It doesn't include the first year instruments that are in warranty. So when you add that almost 60% of our installed base is either under warranty or under a service plan, 55 is a good goal to go with and, you know, we are starting to make progress in the last remaining areas like China.

[Amol Chaubal, Senior VP & CFO at Waters]

And then again, you know, a lot of the focus and pivot our service organization into the next big thing, which is sort of how do we get service lead gen. And we've made tremendous progress in markets like US and India where the attachment rate is very high and these organizations have already pivoted to their next biggest goal, which is lead gen and revenue conversion. And thanks, Catherine, for that question.

[Udit Batra, President & Chief Executive Officer at Waters]

I think we're coming to the end of the call. I want to make sure everybody remembers that March 5 is the Investor Day in New York City, and we look forward to elaborating on the service question, use of AI in service, use of AI internally and externally, and many other areas. But let me conclude by saying we are very excited about how we finished 2024. We're entering this new phase of growth with a lot of momentum, especially on our instrument portfolio. The recurring revenues are growing like a Swiss clock.

[Udit Batra, President & Chief Executive Officer at Waters]

We've said that before. The instrument revenues the instrument growth is is now really kicking into gear with the replacement cycle beginning, with the new product portfolio gaining a ton of traction, with the idiosyncratic growth drivers contributing. And we feel very good about with the way we are starting 2025. Look forward to seeing you at the Investor Day and thank you all for joining us today.

Participants

Executives

• Caspar Tudor, Head, Investor Relations
• Udit Batra, President & Chief Executive Officer
• Amol Chaubal, Senior VP & CFO

Analysts

• Tycho Peterson, Managing Director at Jefferies Financial Group
• Vijay Kumar, Senior Managing Director at Evercore ISI
• Puneet Souda, Senior MD at Leerink Partners
• Eve Burstein, US Life Science Tools and Diagnostics Analyst at Bernstein
• Brandon Couillard, Managing Director at Wells Fargo
• Dan Arias, Managing Director at Stifel Financial Corp
• Analyst
• Daniel Brennan, Managing Director at TD Cowen
• Catherine Schulte, Senior Research Analyst at Baird