Repligen (NASDAQ:RGEN) is a life sciences company that specializes in the development and manufacture of bioprocessing technologies for the production of biologic drugs. Its core offerings include chromatography products, filtration devices and single‐use systems designed to streamline key steps such as antibody capture, virus clearance and ultrafiltration/diafiltration. These solutions are aimed at improving process efficiency, product yield and overall manufacturing consistency for biopharmaceutical customers.
The company’s flagship chromatography portfolio centers on Protein A affinity resins, which are used extensively for monoclonal antibody purification. In addition, Repligen provides tangential flow filtration (TFF) products under the TangenX brand, featuring hollow‐fiber and cassette formats for concentration and buffer exchange. Its OPUS single‐use hollow fiber devices enable scalable cell culture and perfusion processes. Complementing these hardware platforms are pre‐packed columns, analytical tools and service offerings that support process optimization from research through commercial scale.
Founded in 1981 and headquartered in Waltham, Massachusetts, Repligen has evolved from an early‐stage biotechnology developer into a specialized supplier of critical upstream and downstream bioprocessing components. Over the years, the company has expanded its global footprint with manufacturing operations and sales offices in North America, Europe and Asia. Key strategic acquisitions—such as its protein A chromatography business from a major life sciences provider and its tangential flow filtration assets—have bolstered both product breadth and geographic reach.
Serving a diverse base of biopharmaceutical developers and contract manufacturing organizations, Repligen continues to invest in research and development to address emerging needs in cell and gene therapy, antibody‐drug conjugates and other advanced modalities. Its management team combines technical expertise and industry experience, guiding the company’s mission to deliver innovative, reliable tools that help customers accelerate the development and commercialization of life-saving therapies.
