David Cordani
Chairman and Chief Executive Officer at The Cigna Group
Thanks, Ralph. Good morning, everyone, and thanks for joining our call today. For the second quarter, again, we delivered a strong performance, fueled by continued growth across our diverse portfolio of businesses. Today, I'll review key strategic drivers contributing to our momentum and while we believe we're well positioned to sustain our growth as we continue to support the health and vitality of those we serve with our differentiated solutions and capabilities.
Brian will cover additional details about our financial performance in the quarter and our 2023 outlook. As part of our ongoing effort for you to hear more from members of our leadership team, Eric Palmer, President and Chief Executive Officer of Evernorth Health Services, will be joining our call and is available to take your questions. With that, let's get started. In the second quarter, we delivered total revenues of $48.6 billion, adjusted earnings per share of $6.13 and cash flow from operations of $2.5 billion.
We're pleased with our performance overall during the quarter and through the first half of the year. With focus on affordability and innovation, we are continuing to strengthen our competitive position and grow our businesses. In Evernorth Health Services, we saw another strong quarter of our market-leading pharmacy, care and benefits portfolio. Express Scripts, our pharmacy benefits business harnesses our deep relationships, extensive clinical expertise and is delivering innovations and innovative solutions for those we serve.
We've long been a leader in supporting access to prescription drugs and to further enhance our efforts, we took a series of actions in the quarter including launching co-pay assurance to support further affordability for patients and ClearCareRx to provide our clients with broader choice. We also introduced independent Rx, which is a first of its kind support program for rural pharmacists that recognizes the critical role they play in improving access for millions of Americans.
We will continue to lead the way to the current environment of elevated legislative and regulatory activity, and we're encouraged by the positive recognition of our work to make safe, effective and affordable access of prescription drugs within reach for millions of people who need them. Our client retention is also strong, and we are continuing to build and expand new relationships. For example, we're making good progress for our implementation with Centene, which begins on January 2024.
Our teams are working collaboratively, and we are on track as we prepare to further improve affordability in serving 20 million Centene customers. In the quarter, we had strong growth in Accredo, our specialty pharmacy business. In a moment, I'll profile the deep clinical expertise and capabilities that make Accredo a differentiated leader in the space. Turning to Cigna Healthcare. We delivered another quarter of organic customer growth, reinforcing how well our consultative approach and capabilities continue to resonate in the market.
Our U.S. commercial business continues to build momentum. We've had sustained success with commercial customer growth outpacing the overall market, and 2023 is shaping up to be another very strong year for this business. With our affordability initiatives and deep consultative sales approach, we're delivering highly competitive total cost of care for employer clients as well as providing programs supporting healthy engaged workforces that they need.
In U.S. government, our Medicare Advantage business is achieving above-market customer growth with high-quality affordable pains and targeted investments that we continue to make to further strengthen our network and offerings. In our individual exchange business, we will continue taking a focused approach by engaging customers to improve health outcomes and managing risks in the expanding population we serve.
In the quarter, while our medical care ratio is generally in line with expectations, we did have an increase to our 2023 risk adjustment payable. Relative to the risk adjuster impact, we expect this to be a 2023 event, and we've already taken actions for 2024. In our international health business, we drove continued innovation and growth in target markets with solutions for the globally mobile population and employees of multinational corporations as well as into governmental organizations.
Overall, our second quarter results show that the Cigna group is performing well with underlying strength in our complementary businesses. We believe we're well positioned to continue growing our company and deliver on our commitments. With the strength of our results, we are increasing our outlook for full year revenue and customer growth as well as cash flow from operations, and we are reaffirming that we are on track to deliver adjusted EPS of at least $24.70 for full year 2023.
Now I'll talk about how we are working to sustain our momentum with our differentiated and diversified capabilities and our durable strategic growth framework. Our framework guides us in continuing to respond to customer, patient and client needs as well as capturing growth opportunities within our foundational businesses and our accelerated growth businesses. Additionally, we harness the power of our talent, client relationships and partnerships as well as an expanding technology portfolio for cross enterprise leverage.
Technology increasingly provides us with opportunities to accelerate innovation and growth. Artificial intelligence and machine learning, for example, capabilities further enhancing ways for us to support patients in their clinical care teams as well as drive additional efficiency initiatives. Today, I'll talk more about one of our accelerated growth businesses, Accredo, our flagship specialty pharmacy, where we have a competitive advantage in an area of growing need and opportunity.
Earlier this summer, we welcomed a group of investors to Warrendale, Pennsylvania at one of our Accredo clinical care sites. The visit provided an opportunity to see the breadth of our specialty capabilities and the depth of our clinical expertise, a critical driver for the positive outcomes and impact we achieved for patients requiring complex and high-cost treatments for chronic conditions. Here are a few headlines from the day at Warrendale.
First, Accredo has a proven track record of growth. Only five years ago, when Express Scripts combined with Cigna, Here are a few headlines from the day Warrendale. First, Accredo has a proven track record of growth. Only five years ago, when Express Scripts combined with Cigna, Accredo was approximately a $30 billion business. Today, Accredo has grown to approximately $60 billion.
In 2023, serves approximately 900,000 patients with some of the most complex conditions and needs. Accredo now represents about 40% of Evernorth's total revenue and because of its unique strengths, Accredo has grown faster than the overall marketplace. Second is secular tailwinds in the market creates significant growth opportunities as we look to the future.
Those who need specialty drugs make up about 5% of the population and they drive more than 40% of total health care costs across medical, behavioral and pharmacy services. This is fueling expected mid- to high single-digit annual growth in what is already a specialty pharmaceutical market of approximately $380 billion. Biosimilars represent a force of change and a substantial opportunity for further growth and impact, and we will leverage them for greater affordability for clients and patients.
We've long been a leader in supporting greater adoption of biosimilars as we did with the wave of generic medications when they became available decades ago. And like generics, we believe biosimilars will drive much needed affordability improvements for those we serve and thereby, create more financial capacity to pay for new pharmaceutical innovations today and as we look to the future. Third is the breadth of our clinical capabilities and use of data that further fuels precision and impact.
We've built and strengthened our clinical capabilities and far-reaching operating model over decades. Within Accredo, we have therapeutic resource centers with clinical teams of pharmacists, nurse, dietitians and social workers, specializing in different disease states such as blood and neurological disorders and multiple types of cancers. Unlike many of our competitors, we directly employ hundreds of field-based infusion nurses. Today, they are located within 75 miles of approximately 90% of the U.S. population.
And as they care for patients inside their homes, they provide better, more coordinated and personalized experiences, including addressing social determinants of health. With the clinical care models focused on each individual patient, we're able to provide a level of personalized clinical support that is vital in specialty pharmacy. Many new high-cost drugs for oncology, gene therapies and reconditions are coming to market, further pressuring affordability for clients and requiring greater support for patients that take these complex medications safely and effectively.
I would note drug manufacturers also recognize our expertise and capabilities as well as our superior outcomes that we produce with our unique coordinated clinical model. Putting all this together, we're excited about the accelerated growth opportunities we have with Accredo's differentiated specialty pharmacy and view it as a powerful growth engine for our company today and into the future. Now stepping back to the enterprise level, I'll briefly recap.
We drove strong earnings that built on our momentum from the first quarter and last year. We delivered adjusted EPS of $6.13, strong customer, revenue and cash flow growth. Our progress gives us confidence to reaffirm our guidance of adjusted EPS of at least $24.70 for full year 2023, and we also remain on track for adjusted EPS of at least $28 in 2024. This reinforces how we are creating value for our customers and clients and leveraging differentiated capabilities to give us flexibility to continue performing well in a dynamic environment.
Now Brian will share additional perspective about our performance in the quarter and our outlook for the rest of the year. Brian?