NASDAQ:UPB Upstream Bio (UPB) Stock Price, News & Analysis $8.78 +0.36 (+4.28%) Closing price 04/17/2025 04:00 PM EasternExtended Trading$8.76 -0.01 (-0.17%) As of 04/17/2025 04:07 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock About Upstream Bio Stock (NASDAQ:UPB) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get Upstream Bio alerts:Sign Up Key Stats Today's Range$8.13▼$8.9250-Day Range$6.07▼$9.8752-Week Range$5.14▼$29.46Volume315,158 shsAverage Volume325,012 shsMarket Capitalization$470.97 millionP/E RatioN/ADividend YieldN/APrice Target$56.50Consensus RatingBuy Company OverviewUpstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.Read More… Receive UPB Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Upstream Bio and its competitors with MarketBeat's FREE daily newsletter. Email Address UPB Stock News HeadlinesUpstream Bio: Verekitug, A Longer-Acting Dupixent? - Key Data Is ImminentApril 17 at 6:02 PM | seekingalpha.comUpstream Bio Stock Price, Quotes and Forecasts | NASDAQ:UPB | BenzingaApril 11, 2025 | benzinga.comTrump’s Secret WeaponHave you looked at the stock market recently? Millions of investors are scrambling trying to figure out what's coming next. But here's the truth… This is just the beginning. Trump has made it clear his tariffs are coming, and that the market will get worse before it gets better. Luckily, our FREE Presidential Transition Guide details exactly what will happen in the next 100 days, and how to protect your hard-earned savings during these times. Don't wait for the next crash to wipe you out. Act now.April 20, 2025 | American Alternative (Ad)Upstream Bio (NASDAQ:UPB) Is In A Good Position To Deliver On Growth PlansApril 11, 2025 | finance.yahoo.comUpstream Bio’s Financial Results and Strategic ProgressMarch 13, 2025 | tipranks.comUpstream Bio, Inc. Completes Enrollment in Phase 2 Trial of Verekitug for Chronic Rhinosinusitis and Raises $293 Million in IPOMarch 12, 2025 | quiverquant.comUpstream Bio Reports Fourth Quarter and Full Year 2024 Financial Results and Recent Business HighlightsMarch 12, 2025 | globenewswire.comUPB Upstream Bio, Inc.March 8, 2025 | seekingalpha.comSee More Headlines UPB Stock Analysis - Frequently Asked Questions How have UPB shares performed this year? Upstream Bio's stock was trading at $16.44 on January 1st, 2025. Since then, UPB stock has decreased by 46.6% and is now trading at $8.78. View the best growth stocks for 2025 here. When did Upstream Bio IPO? Upstream Bio (UPB) raised $200 million in an IPO on Friday, October 11th 2024. The company issued 12,500,000 shares at a price of $15.00-$17.00 per share. JPMorgan, TD Cowen, Piper Sandler and William Blair acted as the underwriters for the IPO. When did the company's lock-up period expire? Upstream Bio's lock-up period expired on Wednesday, April 9th. Upstream Bio had issued 15,000,000 shares in its IPO on October 11th. The total size of the offering was $255,000,000 based on an initial share price of $17.00. Shares of the company owned by major shareholders and company insiders are now eligible to be traded as a result of the expiration of the lock-up period. Who are Upstream Bio's major shareholders? Top institutional shareholders of Upstream Bio include Rhumbline Advisers (0.02%). Insiders that own company stock include Erez Chimovits and Ai Upstream Llc. View institutional ownership trends. How do I buy shares of Upstream Bio? Shares of UPB stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. Company Calendar Today4/20/2025Next Earnings (Estimated)6/11/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry Pharmaceutical preparations Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:UPB Previous SymbolNASDAQ:UPB CIK2022626 Webupstreambio.com Phone(781) 208-2466FaxN/AEmployees38Year FoundedN/APrice Target and Rating Average Stock Price Target$56.50 High Stock Price Target$75.00 Low Stock Price Target$38.00 Potential Upside/Downside+543.5%Consensus RatingBuy Rating Score (0-4)3.00 Research Coverage4 Analysts Profitability EPS (Most Recent Fiscal Year)N/A Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet IncomeN/A Net MarginsN/A Pretax MarginN/A Return on EquityN/A Return on AssetsN/A Debt Debt-to-Equity RatioN/A Current RatioN/A Quick RatioN/A Sales & Book Value Annual Sales$2.37 million Price / Sales198.72 Cash FlowN/A Price / Cash FlowN/A Book ValueN/A Price / BookN/AMiscellaneous Outstanding Shares53,641,000Free FloatN/AMarket Cap$470.97 million OptionableN/A BetaN/A 7 Energy Stocks to Buy and Hold ForeverWith the proliferation of data centers and electric vehicles, the electric grid will only get more strained. 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