| 2/27/2025 | Jefferies Financial Group Inc. | 40,700 | $101K | 0.0% | +253.9% | 0.057% | |
| 2/18/2025 | Alpine Global Management LLC | 15,340 | $38K | 0.0% | N/A | 0.021% | |
| 2/17/2025 | Velan Capital Investment Management LP | 27,000 | $67K | 0.1% | N/A | 0.038% | |
| 2/17/2025 | Squarepoint Ops LLC | 292,892 | $726K | 0.0% | +108.3% | 0.410% | |
| 2/17/2025 | Two Sigma Advisers LP | 977,400 | $2.42M | 0.0% | -24.9% | 1.368% | |
| 2/17/2025 | Two Sigma Investments LP | 839,270 | $2.08M | 0.0% | -7.6% | 1.175% | |
| 2/17/2025 | Stonepine Capital Management LLC | 663,405 | $1.65M | 1.3% | -73.0% | 0.929% | |
| 2/17/2025 | Man Group plc | 53,534 | $133K | 0.0% | N/A | 0.075% | |
| 2/17/2025 | OMERS ADMINISTRATION Corp | 54,400 | $135K | 0.0% | N/A | 0.076% | |
| 2/17/2025 | Millennium Management LLC | 1,959,047 | $4.86M | 0.0% | -34.8% | 2.743% | |
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| 2/17/2025 | Jacobs Levy Equity Management Inc. | 576,042 | $1.43M | 0.0% | -37.1% | 0.806% | |
| 2/17/2025 | Janus Henderson Group PLC | 2,799,759 | $6.99M | 0.0% | N/A | 3.920% | |
| 2/17/2025 | Jefferies Financial Group Inc. | 40,700 | $101K | 0.0% | +253.9% | 0.057% | |
| 2/17/2025 | Graham Capital Management L.P. | 14,172 | $35K | 0.0% | N/A | 0.020% | |
| 2/17/2025 | D. E. Shaw & Co. Inc. | 3,293,625 | $8.17M | 0.0% | -2.3% | 4.611% | |
| 2/17/2025 | Cubist Systematic Strategies LLC | 256,092 | $635K | 0.0% | +3,573.7% | 0.359% | |
| 2/17/2025 | Bridgeway Capital Management LLC | 281,119 | $697K | 0.0% | +41.2% | 0.394% | |
| 2/17/2025 | Cantor Fitzgerald L. P. | 100,000 | $248K | 0.0% | N/A | 0.140% | |
| 2/17/2025 | Bank of America Corp DE | 205,465 | $510K | 0.0% | +2,246.3% | 0.288% | |
| 2/17/2025 | 683 Capital Management LLC | 217,265 | $539K | 0.0% | N/A | 0.304% | |
| 2/14/2025 | RA Capital Management L.P. | 4,666,667 | $11.57M | 0.2% | N/A | 6.533% | |
| 2/14/2025 | Monashee Investment Management LLC | 888,888 | $2.20M | 0.3% | N/A | 1.244% | |
| 2/14/2025 | Samsara BioCapital LLC | 2,385,060 | $5.92M | 0.8% | +242.6% | 3.339% | |
| 2/14/2025 | Schonfeld Strategic Advisors LLC | 131,895 | $327K | 0.0% | N/A | 0.185% | |
| 2/14/2025 | Northern Trust Corp | 175,175 | $434K | 0.0% | +37.7% | 0.245% | |
| 2/14/2025 | Decheng Capital LLC | 2,266,667 | $5.62M | 1.2% | N/A | 3.173% | |
| 2/14/2025 | Boothbay Fund Management LLC | 112,484 | $279K | 0.0% | N/A | 0.157% | |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 9,627,304 | $23.88M | 0.0% | N/A | 13.478% | |
| 2/14/2025 | Price T Rowe Associates Inc. MD | 123,100 | $306K | 0.0% | -11.7% | 0.172% | |
| 2/14/2025 | Alpine Global Management LLC | 15,340 | $38K | 0.0% | N/A | 0.021% | |
| 2/14/2025 | Rock Springs Capital Management LP | 6,204,309 | $15.39M | 0.6% | +125.3% | 8.686% | |
| 2/14/2025 | Vivo Capital LLC | 8,888,888 | $22.04M | 2.5% | N/A | 12.444% | |
| 2/14/2025 | Dimensional Fund Advisors LP | 239,595 | $594K | 0.0% | +211.9% | 0.335% | |
| 2/13/2025 | Marshall Wace LLP | 2,634,065 | $6.53M | 0.0% | N/A | 3.688% | |
| 2/13/2025 | Walleye Capital LLC | 718,897 | $1.78M | 0.0% | N/A | 1.006% | |
| 2/13/2025 | XTX Topco Ltd | 44,685 | $111K | 0.0% | N/A | 0.063% | |
| 2/13/2025 | Mariner LLC | 37,774 | $94K | 0.0% | -21.5% | 0.053% | |
| 2/13/2025 | Barclays PLC | 15,201 | $38K | 0.0% | -25.5% | 0.021% | |
| 2/13/2025 | Raymond James Financial Inc. | 154,351 | $383K | 0.0% | N/A | 0.216% | |
| 2/13/2025 | Renaissance Technologies LLC | 850,519 | $2.11M | 0.0% | -38.0% | 1.191% | |
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| 2/13/2025 | Invesco Ltd. | 11,215 | $28K | 0.0% | N/A | 0.016% | |
| 2/12/2025 | Aldebaran Capital LLC | 1,016,958 | $2.52M | 2.4% | -2.5% | 1.424% | |
| 2/12/2025 | ExodusPoint Capital Management LP | 10,637 | $26K | 0.0% | N/A | 0.015% | |
| 2/12/2025 | Geode Capital Management LLC | 789,597 | $1.96M | 0.0% | -6.7% | 1.105% | |
| 2/12/2025 | JPMorgan Chase & Co. | 88,320 | $219K | 0.0% | +942.0% | 0.124% | |
| 2/10/2025 | Commonwealth Equity Services LLC | 14,694 | $36K | 0.0% | N/A | 0.021% | |
| 2/10/2025 | Connor Clark & Lunn Investment Management Ltd. | 908,819 | $2.25M | 0.0% | +173.4% | 1.272% | |
| 2/7/2025 | HighTower Advisors LLC | 262,948 | $652K | 0.0% | -14.0% | 0.368% | |
| 2/6/2025 | Raymond James Financial Inc. | 154,351 | $383K | 0.0% | N/A | 0.216% | |
| 2/6/2025 | Charles Schwab Investment Management Inc. | 33,079 | $82K | 0.0% | N/A | 0.046% | |
| 1/29/2025 | Peapod Lane Capital LLC | 404,452 | $1.00M | 1.0% | N/A | 0.566% | |
| 1/14/2025 | Marquette Asset Management LLC | 57,911 | $144K | 0.0% | -31.0% | 0.081% | |
| 1/14/2025 | Assenagon Asset Management S.A. | 397,362 | $985K | 0.0% | +113.9% | 0.556% | |
| 11/16/2024 | Geode Capital Management LLC | 846,446 | $974K | 0.0% | +9.3% | 1.185% | |
| 11/15/2024 | Jane Street Group LLC | 82,727 | $95K | 0.0% | -75.3% | 0.116% | |
| 11/15/2024 | State Street Corp | 188,721 | $217K | 0.0% | -4.0% | 0.264% | |
| 11/15/2024 | Jacobs Levy Equity Management Inc. | 915,509 | $1.05M | 0.0% | N/A | 1.282% | |
| 11/15/2024 | HighTower Advisors LLC | 305,814 | $352K | 0.0% | -2.2% | 0.428% | |
| 11/15/2024 | Point72 Asia Singapore Pte. Ltd. | 52,052 | $60K | 0.0% | -51.8% | 0.073% | |
| 11/14/2024 | Stonepine Capital Management LLC | 2,458,873 | $2.83M | 1.8% | +27.6% | 3.442% | |
| 11/13/2024 | FMR LLC | 545,972 | $628K | 0.0% | -20.8% | 0.764% | |
| 11/8/2024 | Connor Clark & Lunn Investment Management Ltd. | 332,406 | $382K | 0.0% | +187.6% | 0.466% | |
| 11/5/2024 | BML Capital Management LLC | 14,250,000 | $16.39M | 9.6% | +9.7% | 19.973% | |
| 11/5/2024 | GSA Capital Partners LLP | 255,032 | $293K | 0.0% | -24.3% | 0.357% | |
| 10/23/2024 | Assenagon Asset Management S.A. | 185,777 | $214K | 0.0% | N/A | 0.261% | |
| 10/8/2024 | Trium Capital LLP | 1,912,990 | $2.20M | 0.6% | +1.1% | 2.684% | |
| 9/16/2024 | Point72 Asia Singapore Pte. Ltd. | 107,929 | $119K | 0.0% | N/A | 0.151% | |
| 8/21/2024 | Stonepine Capital Management LLC | 1,927,446 | $2.12M | 1.9% | N/A | 2.705% | |
| 8/15/2024 | Millennium Management LLC | 3,336,850 | $3.67M | 0.0% | +1.9% | 4.682% | |
| 8/15/2024 | AQR Capital Management LLC | 386,177 | $425K | 0.0% | -36.9% | 0.542% | |
| 8/15/2024 | Point72 Asia Singapore Pte. Ltd. | 107,929 | $119K | 0.0% | N/A | 0.151% | |
| 8/12/2024 | XTX Topco Ltd | 24,452 | $27K | 0.0% | -80.1% | 0.034% | |
| 8/9/2024 | Renaissance Technologies LLC | 922,200 | $1.01M | 0.0% | -44.9% | 1.294% | |
| 8/9/2024 | Dimensional Fund Advisors LP | 76,759 | $84K | 0.0% | -13.8% | 0.108% | |
| 8/6/2024 | Trium Capital LLP | 1,892,050 | $2.08M | 0.3% | N/A | 2.655% | |
| 8/6/2024 | Acadian Asset Management LLC | 1,913,449 | $2.10M | 0.0% | -10.4% | 2.685% | |
| 8/1/2024 | Rhumbline Advisers | 42,005 | $46K | 0.0% | -56.8% | 0.059% | |
| 7/30/2024 | Deuterium Capital Management LLC | 72,091 | $79K | 0.1% | -9.9% | 0.101% | |
| 5/16/2024 | Bain Capital Life Sciences Investors LLC | 3,000,000 | $3.72M | 0.3% | -14.3% | 4.210% | |
| 5/10/2024 | Acadian Asset Management LLC | 2,135,367 | $2.65M | 0.0% | -9.2% | 2.996% | |
| 5/10/2024 | Vanguard Group Inc. | 4,929,775 | $6.11M | 0.0% | +4.4% | 6.918% | |
| 5/8/2024 | Russell Investments Group Ltd. | 62,772 | $78K | 0.0% | +5,265.1% | 0.088% | |
| 5/7/2024 | SG Americas Securities LLC | 32,843 | $41K | 0.0% | +69.5% | 0.046% | |
| 5/7/2024 | Marquette Asset Management LLC | 83,979 | $104K | 0.0% | N/A | 0.118% | |
| 5/7/2024 | Deuterium Capital Management LLC | 79,993 | $99K | 0.2% | N/A | 0.112% | |
| 5/3/2024 | GSA Capital Partners LLP | 679,137 | $842K | 0.1% | -57.2% | 0.953% | |
| 5/1/2024 | BNP Paribas Financial Markets | 241,101 | $299K | 0.0% | +10.9% | 0.338% | |
| 5/1/2024 | Mirae Asset Global Investments Co. Ltd. | 31,552 | $39K | 0.0% | N/A | 0.044% | |
| 4/23/2024 | BML Capital Management LLC | 9,395,934 | $11.65M | 7.7% | +1,338.7% | 13.248% | |
| 2/15/2024 | Octagon Capital Advisors LP | 100,000 | $105K | 0.0% | N/A | 0.141% | |
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| 2/13/2024 | Bain Capital Life Sciences Investors LLC | 3,500,000 | $3.68M | 0.4% | +2.9% | 4.944% | |
| 2/7/2024 | Monaco Asset Management SAM | 979,399 | $1.03M | 0.3% | N/A | 1.384% | |
| 1/30/2024 | Zurcher Kantonalbank Zurich Cantonalbank | 43,784 | $46K | 0.0% | +115.5% | 0.062% | |
| 1/30/2024 | BML Capital Management LLC | 653,107 | $686K | 0.5% | N/A | 0.923% | |
| 1/30/2024 | Strs Ohio | 193,000 | $202K | 0.0% | +256.7% | 0.273% | |
| 1/30/2024 | Vontobel Holding Ltd. | 30,268 | $32K | 0.0% | +128.8% | 0.043% | |
| 12/18/2023 | Vanguard Group Inc. | 3,363,046 | $23.04M | 0.0% | +1.0% | 4.751% | |
| 12/6/2023 | Citigroup Inc. | 11,864 | $81K | 0.0% | -60.6% | 0.017% | |
| 12/1/2023 | Wellington Management Group LLP | 6,979,844 | $47.81M | 0.0% | -8.6% | 9.860% | |
| 11/14/2023 | Blackstone Inc. | 1,261,425 | $8.64M | 0.0% | +9,578.7% | 1.782% | |
