Avadel Pharmaceuticals (AVDL) Competitors $11.08 +0.57 (+5.42%) Closing price 08/1/2025 04:00 PM EasternExtended Trading$11.02 -0.05 (-0.50%) As of 08/1/2025 07:15 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock AVDL vs. KRYS, MTSR, ABVX, ZLAB, AKRO, ACLX, ACAD, VKTX, SRRK, and PTCTShould you be buying Avadel Pharmaceuticals stock or one of its competitors? The main competitors of Avadel Pharmaceuticals include Krystal Biotech (KRYS), Metsera (MTSR), Abivax (ABVX), Zai Lab (ZLAB), Akero Therapeutics (AKRO), Arcellx (ACLX), ACADIA Pharmaceuticals (ACAD), Viking Therapeutics (VKTX), Scholar Rock (SRRK), and PTC Therapeutics (PTCT). These companies are all part of the "pharmaceutical products" industry. Avadel Pharmaceuticals vs. Its Competitors Krystal Biotech Metsera Abivax Zai Lab Akero Therapeutics Arcellx ACADIA Pharmaceuticals Viking Therapeutics Scholar Rock PTC Therapeutics Krystal Biotech (NASDAQ:KRYS) and Avadel Pharmaceuticals (NASDAQ:AVDL) are both medical companies, but which is the better business? We will compare the two companies based on the strength of their media sentiment, profitability, analyst recommendations, dividends, earnings, risk, valuation and institutional ownership. Do analysts recommend KRYS or AVDL? Krystal Biotech presently has a consensus target price of $211.33, suggesting a potential upside of 34.62%. Avadel Pharmaceuticals has a consensus target price of $18.33, suggesting a potential upside of 65.46%. Given Avadel Pharmaceuticals' higher probable upside, analysts clearly believe Avadel Pharmaceuticals is more favorable than Krystal Biotech.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Krystal Biotech 0 Sell rating(s) 1 Hold rating(s) 8 Buy rating(s) 1 Strong Buy rating(s) 3.00Avadel Pharmaceuticals 0 Sell rating(s) 0 Hold rating(s) 6 Buy rating(s) 0 Strong Buy rating(s) 3.00 Does the media prefer KRYS or AVDL? In the previous week, Krystal Biotech had 13 more articles in the media than Avadel Pharmaceuticals. MarketBeat recorded 16 mentions for Krystal Biotech and 3 mentions for Avadel Pharmaceuticals. Avadel Pharmaceuticals' average media sentiment score of 1.18 beat Krystal Biotech's score of 0.74 indicating that Avadel Pharmaceuticals is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Krystal Biotech 8 Very Positive mention(s) 2 Positive mention(s) 6 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Avadel Pharmaceuticals 2 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Is KRYS or AVDL more profitable? Krystal Biotech has a net margin of 37.17% compared to Avadel Pharmaceuticals' net margin of -13.58%. Krystal Biotech's return on equity of 14.64% beat Avadel Pharmaceuticals' return on equity.Company Net Margins Return on Equity Return on Assets Krystal Biotech37.17% 14.64% 13.28% Avadel Pharmaceuticals -13.58%-36.07%-16.30% Which has more volatility & risk, KRYS or AVDL? Krystal Biotech has a beta of 0.7, indicating that its share price is 30% less volatile than the S&P 500. Comparatively, Avadel Pharmaceuticals has a beta of 1.47, indicating that its share price is 47% more volatile than the S&P 500. Do insiders and institutionals hold more shares of KRYS or AVDL? 86.3% of Krystal Biotech shares are held by institutional investors. Comparatively, 69.2% of Avadel Pharmaceuticals shares are held by institutional investors. 13.7% of Krystal Biotech shares are held by insiders. Comparatively, 5.2% of Avadel Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth. Which has better valuation & earnings, KRYS or AVDL? Krystal Biotech has higher revenue and earnings than Avadel Pharmaceuticals. Avadel Pharmaceuticals is trading at a lower price-to-earnings ratio than Krystal Biotech, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioKrystal Biotech$290.52M15.62$89.16M$4.1637.74Avadel Pharmaceuticals$169.12M6.34-$48.83M-$0.27-41.04 SummaryKrystal Biotech beats Avadel Pharmaceuticals on 13 of the 16 factors compared between the two stocks. Get Avadel Pharmaceuticals News Delivered to You Automatically Sign up to receive the latest news and ratings for AVDL and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding AVDL and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart AVDL vs. The Competition Export to ExcelMetricAvadel PharmaceuticalsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$1.02B$2.47B$5.47B$9.53BDividend YieldN/A1.81%4.74%4.08%P/E Ratio-41.048.9728.6723.80Price / Sales6.34639.64422.2688.08Price / CashN/A157.7635.4557.96Price / Book14.394.838.275.55Net Income-$48.83M$31.62M$3.24B$259.03M7 Day Performance0.45%-5.28%-3.63%-4.56%1 Month Performance25.77%4.38%4.40%4.49%1 Year Performance-32.15%-2.49%25.97%18.05% Avadel Pharmaceuticals Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)AVDLAvadel Pharmaceuticals2.6701 of 5 stars$11.08+5.4%$18.33+65.5%-32.9%$1.02B$169.12M-41.0470News CoveragePositive NewsUpcoming EarningsKRYSKrystal Biotech4.8858 of 5 stars$152.91+3.6%$211.33+38.2%-21.0%$4.27B$290.52M32.88210Upcoming EarningsMTSRMetseraN/A$39.43-2.6%$55.00+39.5%N/A$4.25BN/A0.0081Earnings ReportLockup ExpirationAnalyst RevisionGap DownABVXAbivax3.5887 of 5 stars$66.57+0.1%$80.00+20.2%+511.7%$4.22BN/A0.0061Analyst ForecastGap DownZLABZai Lab2.1983 of 5 stars$38.69+4.1%$54.28+40.3%+99.7%$4.13B$398.99M0.001,869News CoveragePositive NewsUpcoming EarningsShort Interest ↑Gap UpAKROAkero Therapeutics3.9446 of 5 stars$49.24-2.6%$82.50+67.5%+83.6%$4.03BN/A0.0030Positive NewsUpcoming EarningsACLXArcellx2.5739 of 5 stars$70.59-1.0%$111.23+57.6%+21.3%$3.93B$107.94M0.0080News CoveragePositive NewsAnalyst ForecastACADACADIA Pharmaceuticals3.988 of 5 stars$22.62-2.7%$28.13+24.3%+23.9%$3.89B$957.80M34.19510News CoverageUpcoming EarningsAnalyst RevisionVKTXViking Therapeutics3.7591 of 5 stars$33.20-3.5%$86.92+161.8%-40.2%$3.87BN/A0.0020Short Interest ↑SRRKScholar Rock3.7908 of 5 stars$37.09-4.8%$42.67+15.0%+301.3%$3.70B$33.19M0.00140News CoveragePositive NewsUpcoming EarningsAnalyst ForecastPTCTPTC Therapeutics4.482 of 5 stars$44.36-0.9%$65.77+48.3%+59.5%$3.55B$806.78M6.171,410Trending NewsUpcoming EarningsAnalyst ForecastAnalyst Revision Related Companies and Tools Related Companies KRYS Competitors MTSR Competitors ABVX Competitors ZLAB Competitors AKRO Competitors ACLX Competitors ACAD Competitors VKTX Competitors SRRK Competitors PTCT Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:AVDL) was last updated on 8/2/2025 by MarketBeat.com Staff From Our PartnersBuffett to put 90% of his money in this one stock?CPA and CFA says you have WAY too many stocks - just buy these 3 After years working at the biggest accoun...Altimetry | SponsoredHe Called Nvidia at $1.10. 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