Avalo Therapeutics (AVTX) Competitors $4.85 +0.10 (+2.11%) Closing price 07/8/2025 04:00 PM EasternExtended Trading$4.84 -0.01 (-0.31%) As of 07/8/2025 07:50 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock AVTX vs. SOPH, MNPR, SCPH, DSGN, VOR, ACIU, ESPR, PROK, KOD, and SLSShould you be buying Avalo Therapeutics stock or one of its competitors? The main competitors of Avalo Therapeutics include SOPHiA GENETICS (SOPH), Monopar Therapeutics (MNPR), scPharmaceuticals (SCPH), Design Therapeutics (DSGN), Vor Biopharma (VOR), AC Immune (ACIU), Esperion Therapeutics (ESPR), ProKidney (PROK), Kodiak Sciences (KOD), and SELLAS Life Sciences Group (SLS). These companies are all part of the "pharmaceutical products" industry. Avalo Therapeutics vs. Its Competitors SOPHiA GENETICS Monopar Therapeutics scPharmaceuticals Design Therapeutics Vor Biopharma AC Immune Esperion Therapeutics ProKidney Kodiak Sciences SELLAS Life Sciences Group SOPHiA GENETICS (NASDAQ:SOPH) and Avalo Therapeutics (NASDAQ:AVTX) are both small-cap medical companies, but which is the better stock? We will compare the two businesses based on the strength of their media sentiment, analyst recommendations, profitability, earnings, risk, institutional ownership, dividends and valuation. Do analysts rate SOPH or AVTX? SOPHiA GENETICS currently has a consensus price target of $7.00, indicating a potential upside of 96.63%. Avalo Therapeutics has a consensus price target of $30.00, indicating a potential upside of 518.56%. Given Avalo Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Avalo Therapeutics is more favorable than SOPHiA GENETICS.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score SOPHiA GENETICS 0 Sell rating(s) 1 Hold rating(s) 2 Buy rating(s) 0 Strong Buy rating(s) 2.67Avalo Therapeutics 0 Sell rating(s) 0 Hold rating(s) 6 Buy rating(s) 0 Strong Buy rating(s) 3.00 Which has more risk and volatility, SOPH or AVTX? SOPHiA GENETICS has a beta of 1, suggesting that its share price has a similar volatility profile to the S&P 500.Comparatively, Avalo Therapeutics has a beta of 0.77, suggesting that its share price is 23% less volatile than the S&P 500. Does the media prefer SOPH or AVTX? In the previous week, Avalo Therapeutics had 2 more articles in the media than SOPHiA GENETICS. MarketBeat recorded 3 mentions for Avalo Therapeutics and 1 mentions for SOPHiA GENETICS. Avalo Therapeutics' average media sentiment score of 0.34 beat SOPHiA GENETICS's score of 0.00 indicating that Avalo Therapeutics is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment SOPHiA GENETICS 0 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Avalo Therapeutics 1 Very Positive mention(s) 0 Positive mention(s) 2 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Is SOPH or AVTX more profitable? Avalo Therapeutics has a net margin of 0.00% compared to SOPHiA GENETICS's net margin of -98.51%. Avalo Therapeutics' return on equity of 111.00% beat SOPHiA GENETICS's return on equity.Company Net Margins Return on Equity Return on Assets SOPHiA GENETICS-98.51% -63.47% -40.06% Avalo Therapeutics N/A 111.00%58.88% Do insiders & institutionals believe in SOPH or AVTX? 31.6% of SOPHiA GENETICS shares are held by institutional investors. Comparatively, 87.1% of Avalo Therapeutics shares are held by institutional investors. 4.9% of SOPHiA GENETICS shares are held by insiders. Comparatively, 0.3% of Avalo Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term. Which has better valuation and earnings, SOPH or AVTX? Avalo Therapeutics has lower revenue, but higher earnings than SOPHiA GENETICS. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioSOPHiA GENETICS$65.17M3.64-$62.49M-$1.00-3.56Avalo Therapeutics$440K119.38-$35.13MN/AN/A SummaryAvalo Therapeutics beats SOPHiA GENETICS on 11 of the 14 factors compared between the two stocks. Get Avalo Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for AVTX and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding AVTX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart AVTX vs. The Competition Export to ExcelMetricAvalo TherapeuticsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$51.43M$2.39B$5.47B$8.95BDividend YieldN/A1.80%5.25%4.04%P/E RatioN/A8.9826.9620.11Price / Sales119.38729.50430.20119.79Price / CashN/A159.8036.8257.86Price / Book0.384.517.985.56Net Income-$35.13M$31.26M$3.16B$248.40M7 Day Performance-1.82%3.57%2.39%4.67%1 Month Performance6.36%1.28%2.18%6.64%1 Year Performance-62.29%1.08%33.82%21.31% Avalo Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)AVTXAvalo Therapeutics2.9916 of 5 stars$4.85+2.1%$30.00+518.6%-63.1%$51.43M$440K0.0040SOPHSOPHiA GENETICS2.3499 of 5 stars$3.10+0.3%$7.00+125.8%-21.2%$206.06M$65.17M-3.10520News CoveragePositive NewsMNPRMonopar Therapeutics2.8955 of 5 stars$35.78+6.5%$56.50+57.9%+940.0%$205.47MN/A-10.2810News CoverageAnalyst ForecastGap UpSCPHscPharmaceuticals4.1317 of 5 stars$3.81-1.6%$14.00+267.5%-9.4%$204.30M$36.33M-1.9930DSGNDesign Therapeutics0.3745 of 5 stars$3.37-5.6%$4.00+18.7%+4.0%$202.66MN/A-3.4040Positive NewsVORVor Biopharma3.9433 of 5 stars$1.62+52.8%$5.63+247.4%+164.9%$202.44MN/A-0.98140Options VolumeGap UpHigh Trading VolumeACIUAC Immune2.7562 of 5 stars$2.03+1.0%$12.00+491.1%-40.5%$201.82M$31.02M-3.50140ESPREsperion Therapeutics4.2262 of 5 stars$0.98-0.9%$7.00+611.1%-51.3%$196.93M$332.31M-1.23200Positive NewsPROKProKidney0.7394 of 5 stars$0.59-11.5%$3.50+491.1%+68.8%$195.73M$80K-0.993Trending NewsGap UpHigh Trading VolumeKODKodiak Sciences4.1283 of 5 stars$3.73+0.8%$9.00+141.3%+58.5%$195.23MN/A-1.0390News CoverageSLSSELLAS Life Sciences Group0.1221 of 5 stars$2.19+12.3%N/A+77.9%$194.57M$1M-5.7610High Trading Volume Related Companies and Tools Related Companies SOPHiA GENETICS Competitors Monopar Therapeutics Competitors scPharmaceuticals Competitors Design Therapeutics Competitors Vor Biopharma Competitors AC Immune Competitors Esperion Therapeutics Competitors ProKidney Competitors Kodiak Sciences Competitors SELLAS Life Sciences Group Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:AVTX) was last updated on 7/9/2025 by MarketBeat.com Staff From Our PartnersA grave, grave error.I thought what happened 25 years ago was a once- in-a-lifetime event… but how wrong I was. 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