Bicycle Therapeutics (BCYC) Competitors $7.10 +0.01 (+0.14%) Closing price 08/22/2025 04:00 PM EasternExtended Trading$7.16 +0.06 (+0.77%) As of 08/22/2025 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock BCYC vs. ARQT, ADPT, CGON, ANIP, VCEL, BEAM, DYN, APGE, TWST, and TVTXShould you be buying Bicycle Therapeutics stock or one of its competitors? The main competitors of Bicycle Therapeutics include Arcutis Biotherapeutics (ARQT), Adaptive Biotechnologies (ADPT), CG Oncology (CGON), ANI Pharmaceuticals (ANIP), Vericel (VCEL), Beam Therapeutics (BEAM), Dyne Therapeutics (DYN), Apogee Therapeutics (APGE), Twist Bioscience (TWST), and Travere Therapeutics (TVTX). These companies are all part of the "pharmaceutical products" industry. Bicycle Therapeutics vs. Its Competitors Arcutis Biotherapeutics Adaptive Biotechnologies CG Oncology ANI Pharmaceuticals Vericel Beam Therapeutics Dyne Therapeutics Apogee Therapeutics Twist Bioscience Travere Therapeutics Arcutis Biotherapeutics (NASDAQ:ARQT) and Bicycle Therapeutics (NASDAQ:BCYC) are both small-cap medical companies, but which is the superior business? We will compare the two businesses based on the strength of their institutional ownership, risk, dividends, valuation, media sentiment, earnings, analyst recommendations and profitability. Do analysts prefer ARQT or BCYC? Arcutis Biotherapeutics presently has a consensus target price of $19.80, suggesting a potential upside of 23.90%. Bicycle Therapeutics has a consensus target price of $22.22, suggesting a potential upside of 212.99%. Given Bicycle Therapeutics' higher possible upside, analysts clearly believe Bicycle Therapeutics is more favorable than Arcutis Biotherapeutics.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Arcutis Biotherapeutics 0 Sell rating(s) 1 Hold rating(s) 6 Buy rating(s) 0 Strong Buy rating(s) 2.86Bicycle Therapeutics 0 Sell rating(s) 3 Hold rating(s) 7 Buy rating(s) 0 Strong Buy rating(s) 2.70 Does the media prefer ARQT or BCYC? In the previous week, Arcutis Biotherapeutics had 8 more articles in the media than Bicycle Therapeutics. MarketBeat recorded 10 mentions for Arcutis Biotherapeutics and 2 mentions for Bicycle Therapeutics. Bicycle Therapeutics' average media sentiment score of 1.69 beat Arcutis Biotherapeutics' score of 1.13 indicating that Bicycle Therapeutics is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Arcutis Biotherapeutics 6 Very Positive mention(s) 0 Positive mention(s) 2 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Bicycle Therapeutics 2 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Very Positive Do institutionals and insiders have more ownership in ARQT or BCYC? 86.2% of Bicycle Therapeutics shares are held by institutional investors. 9.4% of Arcutis Biotherapeutics shares are held by company insiders. Comparatively, 22.9% of Bicycle Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth. Which has higher valuation and earnings, ARQT or BCYC? Arcutis Biotherapeutics has higher revenue and earnings than Bicycle Therapeutics. Arcutis Biotherapeutics is trading at a lower price-to-earnings ratio than Bicycle Therapeutics, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioArcutis Biotherapeutics$196.54M9.75-$140.04M-$0.75-21.31Bicycle Therapeutics$35.28M13.94-$169.03M-$3.51-2.02 Which has more risk & volatility, ARQT or BCYC? Arcutis Biotherapeutics has a beta of 1.84, suggesting that its stock price is 84% more volatile than the S&P 500. Comparatively, Bicycle Therapeutics has a beta of 1.44, suggesting that its stock price is 44% more volatile than the S&P 500. Is ARQT or BCYC more profitable? Arcutis Biotherapeutics has a net margin of -35.40% compared to Bicycle Therapeutics' net margin of -1,257.00%. Bicycle Therapeutics' return on equity of -32.43% beat Arcutis Biotherapeutics' return on equity.Company Net Margins Return on Equity Return on Assets Arcutis Biotherapeutics-35.40% -62.62% -25.16% Bicycle Therapeutics -1,257.00%-32.43%-26.80% SummaryArcutis Biotherapeutics and Bicycle Therapeutics tied by winning 8 of the 16 factors compared between the two stocks. Get Bicycle Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for BCYC and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding BCYC and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart BCYC vs. The Competition Export to ExcelMetricBicycle TherapeuticsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$491.70M$3.11B$5.81B$9.76BDividend YieldN/A2.23%4.39%4.06%P/E Ratio-2.0221.0031.3626.05Price / Sales13.94209.44387.8788.42Price / CashN/A44.5038.0259.36Price / Book0.738.129.536.60Net Income-$169.03M-$54.72M$3.26B$265.65M7 Day Performance-4.57%2.62%2.14%2.00%1 Month Performance-17.44%3.25%3.22%0.46%1 Year Performance-68.28%10.82%30.18%18.88% Bicycle Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)BCYCBicycle Therapeutics3.6921 of 5 stars$7.10+0.1%$22.22+213.0%-68.3%$491.70M$35.28M-2.02240News CoveragePositive NewsShort Interest ↓ARQTArcutis Biotherapeutics1.7925 of 5 stars$16.74-0.9%$19.80+18.3%+62.6%$2.03B$196.54M-22.32150News CoveragePositive NewsADPTAdaptive Biotechnologies2.4049 of 5 stars$12.41-4.8%$12.38-0.3%+167.5%$1.99B$178.96M-15.13790News CoverageAnalyst RevisionCGONCG Oncology1.3761 of 5 stars$26.13+1.7%$55.30+111.6%-27.3%$1.96B$1.14M-14.7661ANIPANI Pharmaceuticals3.2796 of 5 stars$89.71+2.6%$84.75-5.5%+47.6%$1.90B$614.38M-116.50600News CoverageAnalyst UpgradeInsider TradeVCELVericel2.4884 of 5 stars$36.32+0.1%$60.33+66.1%-24.9%$1.83B$237.22M302.69300Positive NewsBEAMBeam Therapeutics2.406 of 5 stars$17.10-4.0%$48.45+183.4%-37.9%$1.80B$63.52M-3.80510DYNDyne Therapeutics3.4201 of 5 stars$12.33-0.4%$33.80+174.1%-73.0%$1.76BN/A-3.19100APGEApogee Therapeutics3.5567 of 5 stars$36.90-1.0%$99.00+168.3%-20.9%$1.72BN/A-8.9391TWSTTwist Bioscience4.1567 of 5 stars$28.02-0.4%$49.40+76.3%-34.5%$1.70B$312.97M-19.32990Positive NewsTVTXTravere Therapeutics2.4131 of 5 stars$18.77-0.3%$32.21+71.6%+99.6%$1.68B$233.18M-9.20460News CoveragePositive NewsAnalyst Downgrade Related Companies and Tools Related Companies Arcutis Biotherapeutics Competitors Adaptive Biotechnologies Competitors CG Oncology Competitors ANI Pharmaceuticals Competitors Vericel Competitors Beam Therapeutics Competitors Dyne Therapeutics Competitors Apogee Therapeutics Competitors Twist Bioscience Competitors Travere Therapeutics Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:BCYC) was last updated on 8/24/2025 by MarketBeat.com Staff From Our PartnersTrump’s betrayal exposedTrump’s Final Reset Inside the shocking plot to re-engineer America’s financial system…and why you need to ...Porter & Company | SponsoredTrump’s “new dollar” could shock Americans"I Made Millions in the Tech Boom. 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