C4 Therapeutics (CCCC) Stock Price, News & Analysis

Company Overview

C4 Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel therapeutic candidates to degrade disease-causing proteins for the treatment of cancer, neurodegenerative conditions, and other diseases. Its lead product candidate is CFT7455, an orally bioavailable MonoDAC degrader of protein that is in Phase 1/2 trial targeting IKZF1 and IKZF3 for multiple myeloma and non-Hodgkin lymphomas, including peripheral T-cell lymphoma and mantle cell lymphoma, currently under Phase 1/2 clinical trials. The company is also developing CFT1946, an orally bioavailable BiDAC degrader targeting V600X mutant BRAF to treat melanoma, non-small cell lung cancer (NSCLC), colorectal cancer, and other solid malignancies, currently under Phase 1/2 clinical trials; and CFT8919, an orally bioavailable, allosteric, and mutant-selective BiDAC degrader of epidermal growth factor receptor, or EGFR, with an L858R mutation in NSCLC. It has strategic collaborations with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc.; Biogen MA, Inc.; Betta Pharmaceuticals, Co., Ltd.; and Merck Sharp & Dohme, LLC, as well as Calico Life Sciences LLC. The company was incorporated in 2015 and is headquartered in Watertown, Massachusetts.

Key Stats

• Today's Range: $2.29 to $2.43
• 50-Day Range: $1.40 to $2.58
• 52-Week Range: $1.09 to $7.22
• Volume: 998,197 shs
• Average Volume: 1.71 million shs
• Market Capitalization: $167.25 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $8.00
• Consensus Rating: Hold

C4 Therapeutics Stock Analysis - MarketRank™

C4 Therapeutics scored higher than 43% of companies evaluated by MarketBeat, and ranked 676th out of 935 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.2 / 5
• Analyst Rating: Hold

Consensus Rating

C4 Therapeutics has received a consensus rating of Hold. The company's average rating score is 2.33, and is based on 1 buy rating, 2 hold ratings, and no sell ratings.

Amount of Analyst Coverage

C4 Therapeutics has received no research coverage in the past 90 days.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Decreasing

Earnings Growth

Earnings for C4 Therapeutics are expected to decrease in the coming year, from ($1.52) to ($1.70) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of C4 Therapeutics is -1.49, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of C4 Therapeutics is -1.49, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

C4 Therapeutics has a P/B Ratio of 0.96. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.

Short Interest

• Score: 2.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

7.17% of the float of C4 Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

C4 Therapeutics has a short interest ratio ("days to cover") of 3.2, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in C4 Therapeutics has recently increased by 14.50%, indicating that investor sentiment is decreasing significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

C4 Therapeutics does not currently pay a dividend.

Dividend Growth

C4 Therapeutics does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

7.17% of the float of C4 Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

C4 Therapeutics has a short interest ratio ("days to cover") of 3.2, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in C4 Therapeutics has recently increased by 14.50%, indicating that investor sentiment is decreasing significantly.

News and Social Media

• Score: 2.3 / 5
• News Sentiment: 0.18

News Sentiment

C4 Therapeutics has a news sentiment score of 0.18. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.61 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 7 news articles for C4 Therapeutics this week, compared to 2 articles on an average week.

Search Interest

3 people have searched for CCCC on MarketBeat in the last 30 days. This is an increase of 200% compared to the previous 30 days.

Company Ownership

• Score: 1.7 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, C4 Therapeutics insiders have not sold or bought any company stock.

Percentage Held by Insiders

Only 8.73% of the stock of C4 Therapeutics is held by insiders.

Percentage Held by Institutions

78.81% of the stock of C4 Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

CCCC Stock Analysis - Frequently Asked Questions

How have CCCC shares performed this year?

C4 Therapeutics' stock was trading at $3.60 on January 1st, 2025. Since then, CCCC shares have decreased by 34.7% and is now trading at $2.35.

How were C4 Therapeutics' earnings last quarter?

C4 Therapeutics, Inc. (NASDAQ:CCCC) released its quarterly earnings data on Thursday, August, 7th. The company reported ($0.37) earnings per share (EPS) for the quarter, topping the consensus estimate of ($0.38) by $0.01. The firm earned $6.46 million during the quarter, compared to analyst estimates of $5.24 million. C4 Therapeutics had a negative trailing twelve-month return on equity of 53.91% and a negative net margin of 325.88%.

When did C4 Therapeutics IPO?

C4 Therapeutics (CCCC) raised $150 million in an initial public offering on Friday, October 2nd 2020. The company issued 8,800,000 shares at $16.00-$18.00 per share. Jefferies, Evercore ISI, BMO Capital Markets and UBS Investment Bank served as the underwriters for the IPO.

Who are C4 Therapeutics' major shareholders?

C4 Therapeutics' top institutional shareholders include Geode Capital Management LLC (1.05%), Jane Street Group LLC (0.69%), Invesco Ltd. (0.22%) and XTX Topco Ltd (0.15%).
View institutional ownership trends.

How do I buy shares of C4 Therapeutics?

Shares of CCCC stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of C4 Therapeutics own?

Based on aggregate information from My MarketBeat watchlists, some other companies that C4 Therapeutics investors own include Sangamo Therapeutics (SGMO), Meta Platforms (META), Tesla (TSLA), Netflix (NFLX), Advanced Micro Devices (AMD), NVIDIA (NVDA) and JPMorgan Chase & Co. (JPM).

Company Calendar

• Last Earnings: 8/07/2025
• Today: 8/14/2025
• Next Earnings (Estimated): 10/30/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:CCCC
• CIK: 1662579
• Web: www.c4therapeutics.com
• Phone: 617-231-0700
• Fax: N/A
• Employees: 150
• Year Founded: N/A

Price Target and Rating

• Average Price Target for C4 Therapeutics: $8.00
• High Price Target: $12.00
• Low Price Target: $4.00
• Potential Upside/Downside: +240.4%
• Consensus Rating: Hold
• Rating Score (0-4): 2.33
• Research Coverage: 3 Analysts

Profitability

• EPS (Trailing Twelve Months): ($1.58)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$105.32 million
• Net Margins: -325.88%
• Pretax Margin: -325.50%
• Return on Equity: -53.91%
• Return on Assets: -33.26%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 5.06
• Quick Ratio: 5.06

Sales & Book Value

• Annual Sales: $35.58 million
• Price / Sales: 4.70
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $2.45 per share
• Price / Book: 0.96

Miscellaneous

• Outstanding Shares: 71,170,000
• Free Float: 64,958,000
• Market Cap: $167.25 million
• Optionable: Optionable
• Beta: 2.97