Clearside Biomedical (CLSD) Competitors $0.86 -0.01 (-1.13%) Closing price 04/17/2025 04:00 PM EasternExtended Trading$0.87 +0.01 (+0.93%) As of 04/17/2025 06:09 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock CLSD vs. TSVT, AQST, TSHA, ATXS, ATYR, ATAI, CMPS, GLUE, ARCT, and TKNOShould you be buying Clearside Biomedical stock or one of its competitors? The main competitors of Clearside Biomedical include 2seventy bio (TSVT), Aquestive Therapeutics (AQST), Taysha Gene Therapies (TSHA), Astria Therapeutics (ATXS), Atyr PHARMA (ATYR), Atai Life Sciences (ATAI), COMPASS Pathways (CMPS), Monte Rosa Therapeutics (GLUE), Arcturus Therapeutics (ARCT), and Alpha Teknova (TKNO). These companies are all part of the "pharmaceutical products" industry. Clearside Biomedical vs. 2seventy bio Aquestive Therapeutics Taysha Gene Therapies Astria Therapeutics Atyr PHARMA Atai Life Sciences COMPASS Pathways Monte Rosa Therapeutics Arcturus Therapeutics Alpha Teknova Clearside Biomedical (NASDAQ:CLSD) and 2seventy bio (NASDAQ:TSVT) are both small-cap medical companies, but which is the better stock? We will compare the two companies based on the strength of their risk, institutional ownership, analyst recommendations, media sentiment, earnings, dividends, valuation, community ranking and profitability. Does the media prefer CLSD or TSVT? In the previous week, Clearside Biomedical and Clearside Biomedical both had 2 articles in the media. Clearside Biomedical's average media sentiment score of 0.88 beat 2seventy bio's score of 0.53 indicating that Clearside Biomedical is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Clearside Biomedical 1 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive 2seventy bio 0 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Which has higher valuation and earnings, CLSD or TSVT? Clearside Biomedical has higher earnings, but lower revenue than 2seventy bio. 2seventy bio is trading at a lower price-to-earnings ratio than Clearside Biomedical, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioClearside Biomedical$1.66M39.94-$32.49M-$0.47-1.832seventy bio$37.86M6.88-$217.57M-$1.12-4.45 Is CLSD or TSVT more profitable? 2seventy bio has a net margin of -207.25% compared to Clearside Biomedical's net margin of -413.83%. Clearside Biomedical's return on equity of 0.00% beat 2seventy bio's return on equity.Company Net Margins Return on Equity Return on Assets Clearside Biomedical-413.83% N/A -92.90% 2seventy bio -207.25%-53.65%-23.67% Do analysts rate CLSD or TSVT? Clearside Biomedical presently has a consensus target price of $5.25, indicating a potential upside of 510.47%. 2seventy bio has a consensus target price of $5.60, indicating a potential upside of 12.45%. Given Clearside Biomedical's stronger consensus rating and higher probable upside, equities research analysts clearly believe Clearside Biomedical is more favorable than 2seventy bio.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Clearside Biomedical 0 Sell rating(s) 0 Hold rating(s) 4 Buy rating(s) 0 Strong Buy rating(s) 3.002seventy bio 1 Sell rating(s) 4 Hold rating(s) 1 Buy rating(s) 1 Strong Buy rating(s) 2.29 Which has more volatility & risk, CLSD or TSVT? Clearside Biomedical has a beta of 2.04, meaning that its stock price is 104% more volatile than the S&P 500. Comparatively, 2seventy bio has a beta of 1.04, meaning that its stock price is 4% more volatile than the S&P 500. Does the MarketBeat Community believe in CLSD or TSVT? Clearside Biomedical received 349 more outperform votes than 2seventy bio when rated by MarketBeat users. Likewise, 67.51% of users gave Clearside Biomedical an outperform vote while only 46.30% of users gave 2seventy bio an outperform vote. CompanyUnderperformOutperformClearside BiomedicalOutperform Votes37467.51% Underperform Votes18032.49% 2seventy bioOutperform Votes2546.30% Underperform Votes2953.70% Do insiders and institutionals have more ownership in CLSD or TSVT? 18.8% of Clearside Biomedical shares are held by institutional investors. Comparatively, 93.9% of 2seventy bio shares are held by institutional investors. 9.2% of Clearside Biomedical shares are held by insiders. Comparatively, 7.2% of 2seventy bio shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth. SummaryClearside Biomedical beats 2seventy bio on 13 of the 18 factors compared between the two stocks. Get Clearside Biomedical News Delivered to You Automatically Sign up to receive the latest news and ratings for CLSD and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart CLSD vs. The Competition Export to ExcelMetricClearside BiomedicalPharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$66.46M$6.45B$5.30B$7.35BDividend YieldN/A3.23%5.12%4.30%P/E Ratio-1.916.8921.8017.80Price / Sales39.94231.03379.9697.74Price / CashN/A65.6738.2634.64Price / Book-3.445.936.443.98Net Income-$32.49M$142.99M$3.21B$247.73M7 Day Performance12.43%4.42%2.87%1.81%1 Month Performance-11.34%-12.73%-8.63%-6.98%1 Year Performance-34.85%-9.48%11.46%1.37% Clearside Biomedical Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)CLSDClearside Biomedical2.9137 of 5 stars$0.86-1.1%$5.25+510.5%-31.7%$66.46M$1.66M-1.9130Short Interest ↓TSVT2seventy bio1.9611 of 5 stars$4.95flat$6.67+34.7%-1.6%$259.07M$37.86M-2.66440Short Interest ↓Positive NewsHigh Trading VolumeAQSTAquestive Therapeutics1.8405 of 5 stars$2.62-3.3%$10.57+303.5%-36.0%$259.04M$57.56M-5.82160Gap DownTSHATaysha Gene Therapies2.8196 of 5 stars$1.24+1.6%$6.63+434.3%-49.4%$254.20M$8.33M1.97180ATXSAstria Therapeutics1.7909 of 5 stars$4.50-3.4%$26.60+491.1%-61.7%$253.95MN/A-2.1530Gap DownATYRAtyr PHARMA2.5913 of 5 stars$2.85+8.8%$18.60+552.6%N/A$253.25M$235,000.00-3.0353Positive NewsATAIAtai Life Sciences1.9077 of 5 stars$1.27-3.1%$10.50+726.8%-25.8%$251.85M$308,000.00-1.5780Positive NewsGap UpCMPSCOMPASS Pathways2.5424 of 5 stars$2.70-0.4%$20.20+648.1%-63.3%$250.22MN/A-1.23120News CoverageGap UpGLUEMonte Rosa Therapeutics3.1307 of 5 stars$4.05+2.5%$15.50+282.7%-21.6%$249.12M$75.62M-2.2190Short Interest ↓Positive NewsARCTArcturus Therapeutics2.776 of 5 stars$9.09-0.2%$59.20+551.3%-61.9%$246.52M$138.39M-4.09180Analyst RevisionNews CoverageTKNOAlpha Teknova1.1833 of 5 stars$4.51-3.6%$8.50+88.5%+173.0%$241.00M$37.75M-6.09240Positive NewsGap Up Related Companies and Tools Related Companies 2seventy bio Competitors Aquestive Therapeutics Competitors Taysha Gene Therapies Competitors Astria Therapeutics Competitors Atyr PHARMA Competitors Atai Life Sciences Competitors COMPASS Pathways Competitors Monte Rosa Therapeutics Competitors Arcturus Therapeutics Competitors Alpha Teknova Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:CLSD) was last updated on 4/18/2025 by MarketBeat.com Staff From Our PartnersElon Reveals Why There Soon Won’t Be Any Money For Social SecurityElon Musk's Near-Death Experience Sparks Dire Warning for Americans After cheating death twice—once in a te...Colonial Metals | SponsoredClaim Your FREE Protection GuideIn the final days of his first term, Trump quietly left open an "off the books" wealth-protection loophole hid...American Alternative | SponsoredThe first casualty of the 2025 trade warThe headlines scream tariffs and export bans — but the real damage is happening in retirement portfolios. 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