Caribou Biosciences (CRBU) Competitors $1.36 -0.01 (-0.73%) Closing price 07/3/2025 03:22 PM EasternExtended Trading$1.36 0.00 (0.00%) As of 07/3/2025 04:27 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock CRBU vs. SEPN, ORGO, SIGA, CGEM, ATYR, KMDA, ATAI, TRML, MREO, and RGNXShould you be buying Caribou Biosciences stock or one of its competitors? The main competitors of Caribou Biosciences include Septerna (SEPN), Organogenesis (ORGO), Siga Technologies (SIGA), Cullinan Therapeutics (CGEM), aTyr Pharma (ATYR), Kamada (KMDA), atai Life Sciences (ATAI), Tourmaline Bio (TRML), Mereo BioPharma Group (MREO), and REGENXBIO (RGNX). These companies are all part of the "pharmaceutical products" industry. Caribou Biosciences vs. Its Competitors Septerna Organogenesis Siga Technologies Cullinan Therapeutics aTyr Pharma Kamada atai Life Sciences Tourmaline Bio Mereo BioPharma Group REGENXBIO Caribou Biosciences (NASDAQ:CRBU) and Septerna (NASDAQ:SEPN) are both small-cap medical companies, but which is the better investment? We will compare the two businesses based on the strength of their risk, valuation, institutional ownership, media sentiment, analyst recommendations, dividends, earnings and profitability. Do analysts rate CRBU or SEPN? Caribou Biosciences currently has a consensus target price of $8.50, indicating a potential upside of 525.00%. Septerna has a consensus target price of $26.75, indicating a potential upside of 136.73%. Given Caribou Biosciences' stronger consensus rating and higher probable upside, equities research analysts plainly believe Caribou Biosciences is more favorable than Septerna.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Caribou Biosciences 0 Sell rating(s) 0 Hold rating(s) 4 Buy rating(s) 0 Strong Buy rating(s) 3.00Septerna 0 Sell rating(s) 1 Hold rating(s) 4 Buy rating(s) 0 Strong Buy rating(s) 2.80 Which has stronger earnings & valuation, CRBU or SEPN? Septerna has lower revenue, but higher earnings than Caribou Biosciences. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioCaribou Biosciences$9.99M12.66-$149.10M-$1.62-0.84Septerna$1.08M466.23-$71.80MN/AN/A Does the media prefer CRBU or SEPN? In the previous week, Caribou Biosciences had 3 more articles in the media than Septerna. MarketBeat recorded 3 mentions for Caribou Biosciences and 0 mentions for Septerna. Caribou Biosciences' average media sentiment score of 0.83 beat Septerna's score of 0.79 indicating that Caribou Biosciences is being referred to more favorably in the media. Company Overall Sentiment Caribou Biosciences Positive Septerna Positive Do insiders & institutionals believe in CRBU or SEPN? 77.5% of Caribou Biosciences shares are held by institutional investors. 8.3% of Caribou Biosciences shares are held by company insiders. Comparatively, 4.3% of Septerna shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term. Is CRBU or SEPN more profitable? Septerna has a net margin of 0.00% compared to Caribou Biosciences' net margin of -1,490.84%. Septerna's return on equity of 0.00% beat Caribou Biosciences' return on equity.Company Net Margins Return on Equity Return on Assets Caribou Biosciences-1,490.84% -55.70% -45.35% Septerna N/A N/A N/A SummaryCaribou Biosciences beats Septerna on 7 of the 12 factors compared between the two stocks. Get Caribou Biosciences News Delivered to You Automatically Sign up to receive the latest news and ratings for CRBU and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding CRBU and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart CRBU vs. The Competition Export to ExcelMetricCaribou BiosciencesMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$127.42M$2.91B$5.54B$9.05BDividend YieldN/A2.44%5.24%4.03%P/E Ratio-0.8421.5627.4320.23Price / Sales12.66281.76420.79118.64Price / CashN/A42.7336.8958.07Price / Book0.497.518.045.67Net Income-$149.10M-$55.05M$3.18B$249.13M7 Day Performance7.94%4.61%2.88%3.28%1 Month Performance24.77%4.72%3.69%5.56%1 Year Performance-15.00%5.92%36.15%21.12% Caribou Biosciences Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)CRBUCaribou Biosciences2.3028 of 5 stars$1.36-0.7%$8.50+525.0%-15.0%$127.42M$9.99M-0.84100News CoverageAnalyst UpgradeSEPNSepterna1.691 of 5 stars$10.57+0.6%$26.75+153.1%N/A$468.31M$1.08M0.00N/AORGOOrganogenesis4.0835 of 5 stars$3.66-0.3%$6.00+63.9%+55.9%$465.55M$482.04M-21.53950News CoverageSIGASiga Technologies0.9193 of 5 stars$6.52+0.9%N/A-13.0%$461.51M$138.72M9.7340CGEMCullinan Therapeutics1.5334 of 5 stars$7.53-3.0%$30.00+298.4%-53.5%$457.95MN/A-2.5930Positive NewsGap UpATYRaTyr Pharma2.9814 of 5 stars$5.07+0.8%$20.20+298.4%N/A$447.69M$230K-6.2653Gap UpHigh Trading VolumeKMDAKamada4.052 of 5 stars$7.75+0.5%$14.67+89.2%+50.6%$443.36M$160.95M26.72360News CoveragePositive NewsATAIatai Life Sciences2.9983 of 5 stars$2.19-0.5%$8.67+295.7%+116.8%$440.74M$310K-2.4180Analyst ForecastOptions VolumeTRMLTourmaline Bio2.1424 of 5 stars$15.99-3.3%$49.33+208.5%+30.7%$424.84MN/A-4.9844MREOMereo BioPharma Group1.9697 of 5 stars$2.71+1.9%$7.60+180.4%-19.9%$422.94M$10M-38.7140Positive NewsRGNXREGENXBIO4.5283 of 5 stars$8.21-2.1%$31.63+285.2%-19.3%$420.85M$83.33M-2.64370Positive News Related Companies and Tools Related Companies Septerna Competitors Organogenesis Competitors Siga Technologies Competitors Cullinan Therapeutics Competitors aTyr Pharma Competitors Kamada Competitors atai Life Sciences Competitors Tourmaline Bio Competitors Mereo BioPharma Group Competitors REGENXBIO Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:CRBU) was last updated on 7/5/2025 by MarketBeat.com Staff From Our PartnersTrump’s New Order Could Boost Social Security Benefits by 400%If you collect—or plan to collect—Social Security, you need to see this. 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