Denali Therapeutics (DNLI) Institutional Ownership $15.27 -0.38 (-2.43%) Closing price 08/29/2025 04:00 PM EasternExtended Trading$15.36 +0.09 (+0.59%) As of 08/29/2025 06:02 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Denali Therapeutics (NASDAQ:DNLI)CurrentInstitutional OwnershipPercentage92.92%Number ofInstitutional Buyers(last 12 months)140TotalInstitutional Inflows(last 12 months)$707.33MNumber ofInstitutional Sellers(last 12 months)87TotalInstitutional Outflows(last 12 months)$258.72M Get DNLI Insider Trade Alerts Want to know when executives and insiders are buying or selling Denali Therapeutics stock? Sign up for InsiderTrades.com's daily newsletter to get the latest insider transactions delivered to your inbox daily. 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Skip Chart & View Institutional Buying and Selling Data DNLI Institutional Buying and Selling by Quarter Denali Therapeutics Major Shareholders & Ownership History Export to ExcelReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails8/19/2025 Marex Group plc262,000$3.67M0.0%N/A0.179% 8/19/2025 State of Wyoming2,099$29K0.0%N/A0.001% 8/18/2025 Hudson Bay Capital Management LP290,000$4.06M0.0%+16.0%0.198% 8/18/2025 Caxton Associates LLP14,229$199K0.0%N/A0.010% 8/16/2025 Headlands Technologies LLC1,847$26K0.0%N/A0.001% 8/15/2025 Tower Research Capital LLC TRC 13,669$191K0.0%+325.6%0.009% 8/15/2025 E Fund Management Co. Ltd.13,612$190K0.0%+12.8%0.009% 8/15/2025 Soleus Capital Management L.P.182,110$2.55M0.2%+34.9%0.125% 8/15/2025 Rafferty Asset Management LLC122,262$1.71M0.0%-5.3%0.084% 8/15/2025 Man Group plc70,028$980K0.0%-58.7%0.048% Get the Latest News and Ratings for DNLI and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Denali Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 8/15/2025 Holocene Advisors LP403,172$5.64M0.0%N/A0.276% 8/15/2025 Hudson Bay Capital Management LP290,000$4.06M0.0%+16.0%0.198% 8/15/2025 Engineers Gate Manager LP116,101$1.62M0.0%+575.1%0.079% 8/15/2025 Cubist Systematic Strategies LLC396,586$5.55M0.0%N/A0.271% 8/15/2025 BNP Paribas Financial Markets19,082$267K0.0%+119.0%0.013% 8/15/2025 Bank of America Corp DE650,222$9.10M0.0%+45.2%0.445% 8/15/2025 Ameriprise Financial Inc.102,033$1.43M0.0%N/A0.070% 8/14/2025 California State Teachers Retirement System119,327$1.67M0.0%+1.5%0.082% 8/14/2025 Camber Capital Management LP400,000$5.60M0.5%-68.0%0.274% 8/14/2025 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.134,703$1.89M0.0%+52.2%0.092% 8/14/2025 Alliancebernstein L.P.3,137,140$43.89M0.0%-0.5%2.146% 8/14/2025 The Manufacturers Life Insurance Company 315,102$4.41M0.0%+22.1%0.216% 8/14/2025 Stempoint Capital LP707,915$9.90M3.2%+6.1%0.484% 8/13/2025 Marshall Wace LLP1,405,250$19.66M0.0%-35.8%0.967% 8/13/2025 Guggenheim Capital LLC51,860$726K0.0%-7.4%0.036% 8/13/2025 Invesco Ltd.219,795$3.08M0.0%+16.0%0.151% 8/13/2025 Fisher Asset Management LLC1,515,991$21.21M0.0%+11.1%1.044% 8/13/2025 Edgestream Partners L.P.342,923$4.80M0.1%N/A0.236% 8/13/2025 New York State Common Retirement Fund38,478$538K0.0%-45.2%0.026% 8/13/2025 Schroder Investment Management Group386,539$5.41M0.0%+32.5%0.266% 8/13/2025 Norges Bank3,947,387$55.22M0.0%N/A2.717% 8/13/2025 Capital Fund Management S.A.21,871$306K0.0%N/A0.015% 8/13/2025 Groupama Asset Managment175,531$2.48M0.0%+21.5%0.121% 8/12/2025 Ameritas Investment Partners Inc.13,522$189K0.0%+7.4%0.009% 8/12/2025 Prudential Financial Inc.16,878$236K0.0%-56.3%0.012% 8/12/2025 American Century Companies Inc.318,193$4.45M0.0%-8.9%0.219% 8/12/2025 Segall Bryant & Hamill LLC500,559$7.00M0.1%+78.0%0.345% 8/12/2025 Rhumbline Advisers212,503$2.97M0.0%+11.7%0.146% 8/12/2025 Franklin Resources Inc.64,525$903K0.0%-22.5%0.044% 8/12/2025 Legal & General Group Plc131,755$1.84M0.0%-13.3%0.091% When the levee breaks (Ad)The U.S. Treasury just confirmed it plans to borrow $1.01 trillion this quarter—nearly double what was projected. According to Porter Stansberry, this is panic-level borrowing… and a clear sign we’re nearing America’s financial breaking point. In his latest emergency briefing, Porter outlines why the cracks in our system are widening fast—and how Trump’s policies may be accelerating the collapse. More importantly, he reveals three moves you can make now to protect and potentially grow your wealth before the levee breaks.Click here to watch the urgent broadcast and get ahead of what’s coming.8/12/2025 JPMorgan Chase & Co.191,613$2.68M0.0%+1.7%0.132% 8/12/2025 Ensign Peak Advisors Inc473,695$6.63M0.0%-19.4%0.326% 8/11/2025 Universal Beteiligungs und Servicegesellschaft mbH21,484$301K0.0%+14.9%0.015% 8/8/2025 Intech Investment Management LLC71,866$1.01M0.0%-7.4%0.049% 8/8/2025 Creative Planning57,678$807K0.0%+88.7%0.040% 8/8/2025 Candriam S.C.A.844,249$11.81M0.1%-1.6%0.581% 8/8/2025 Police & Firemen s Retirement System of New Jersey30,394$425K0.0%+14.8%0.021% 8/8/2025 Geode Capital Management LLC3,172,305$44.39M0.0%+4.4%2.184% 8/8/2025 PNC Financial Services Group Inc.8,236$115K0.0%+120.1%0.006% 8/8/2025 KBC Group NV4,495$63K0.0%-30.3%0.003% 8/7/2025 ProShare Advisors LLC32,582$456K0.0%-2.6%0.022% 8/7/2025 Profund Advisors LLC26,723$374K0.0%-4.1%0.018% 8/7/2025 Pier 88 Investment Partners LLC57,150$800K0.1%+27.3%0.039% 8/7/2025 Campbell & CO Investment Adviser LLC142,708$2.00M0.1%+109.3%0.098% 8/5/2025 Bank of New York Mellon Corp790,756$11.06M0.0%-28.4%0.544% 8/5/2025 Pier Capital LLC314,796$4.40M0.7%-6.2%0.217% 8/4/2025 Savvy Advisors Inc.97,793$1.37M0.1%N/A0.067% 8/1/2025 Envestnet Asset Management Inc.33,538$469K0.0%+6.7%0.023% 7/31/2025 State of New Jersey Common Pension Fund D137,880$1.93M0.0%+47.3%0.095% 7/31/2025 AlphaQuest LLC22,964$321K0.0%-8.4%0.016% 7/30/2025 DekaBank Deutsche Girozentrale59,800$841K0.0%-6.9%0.041% 7/28/2025 TD Asset Management Inc496,290$6.94M0.0%+60.8%0.342% 7/25/2025 Vanguard Personalized Indexing Management LLC15,329$214K0.0%N/A0.011% 7/24/2025 Aberdeen Group plc902,751$12.63M0.0%+18.8%0.621% 7/22/2025 Knights of Columbus Asset Advisors LLC38,479$538K0.0%-4.5%0.026% 7/21/2025 Mirae Asset Global Investments Co. Ltd.5,612$79K0.0%+15.5%0.004% 7/10/2025 TT International Asset Management LTD65,000$909K0.2%N/A0.045% 7/9/2025 Breakwater Capital Group17,096$239K0.0%+13.9%0.012% 6/18/2025 Voya Investment Management LLC51,011$693K0.0%-6.9%0.035% 5/28/2025 Strs Ohio23,800$324K0.0%N/A0.016% 5/23/2025 Siren L.L.C.821,513$11.17M0.6%-1.5%0.565% 5/19/2025 Jane Street Group LLC213,673$2.91M0.0%-6.8%0.147% 5/19/2025 SCS Capital Management LLC197,998$2.69M0.0%N/A0.136% 5/19/2025 UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC6,766,916$92.00M0.0%+88.9%4.658% 5/16/2025 Woodline Partners LP113,517$1.54M0.0%+13.5%0.078% 5/16/2025 Empowered Funds LLC20,639$281K0.0%+11.0%0.014% 5/16/2025 Goldman Sachs Group Inc.1,672,078$22.73M0.0%+58.1%1.151% 5/16/2025 Yiheng Capital Management L.P.469,981$6.39M0.6%-32.9%0.324% 5/16/2025 Polar Asset Management Partners Inc.20,952$285K0.0%-96.2%0.014% 5/16/2025 Millennium Management LLC1,493,068$20.30M0.0%+269.4%1.028% 5/16/2025 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.88,507$1.21M0.0%+4.0%0.061% 5/16/2025 Crestline Management LP4,160,732$56.57M89.5%-3.5%2.864% 5/16/2025 Alliancebernstein L.P.3,154,387$42.88M0.0%-4.9%2.171% 5/16/2025 ADAR1 Capital Management LLC13,873$189K0.0%-69.1%0.010% 5/15/2025 Graham Capital Management L.P.43,005$585K0.0%+107.7%0.030% 5/15/2025 DAFNA Capital Management LLC127,900$1.74M0.5%N/A0.088% 5/15/2025 Yiheng Capital Management L.P.469,981$6.39M0.4%-32.9%0.324% 5/15/2025 Siren L.L.C.821,513$11.17M0.7%-1.5%0.565% 5/15/2025 Tema Etfs LLC15,174$206K0.1%N/A0.010% 5/15/2025 Trexquant Investment LP113,224$1.54M0.0%+86.7%0.078% When the levee breaks (Ad)The U.S. Treasury just confirmed it plans to borrow $1.01 trillion this quarter—nearly double what was projected. According to Porter Stansberry, this is panic-level borrowing… and a clear sign we’re nearing America’s financial breaking point. In his latest emergency briefing, Porter outlines why the cracks in our system are widening fast—and how Trump’s policies may be accelerating the collapse. More importantly, he reveals three moves you can make now to protect and potentially grow your wealth before the levee breaks.Click here to watch the urgent broadcast and get ahead of what’s coming.5/14/2025 Rafferty Asset Management LLC129,135$1.76M0.0%-8.6%0.089% 5/14/2025 Corebridge Financial Inc.60,898$828K0.0%-1.5%0.042% 5/14/2025 MetLife Investment Management LLC74,765$1.02M0.0%-1.7%0.051% 5/14/2025 Walleye Capital LLC44,138$600K0.0%+77.8%0.030% 5/14/2025 AlphaQuest LLC25,060$341K0.0%+260.0%0.017% 5/14/2025 Price T Rowe Associates Inc. MD4,367,234$59.37M0.0%+42.8%3.006% 5/14/2025 Candriam S.C.A.858,162$11.67M0.1%+3.0%0.591% 5/14/2025 Groupama Asset Managment144,488$2.14M0.0%+31.1%0.099% 5/14/2025 BI Asset Management Fondsmaeglerselskab A S2,988$41K0.0%N/A0.002% 5/14/2025 Hsbc Holdings PLC58,003$779K0.0%+73.7%0.040% (Data available from 1/1/2016 forward) DNLI Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of DNLI shares? During the previous two years, 223 institutional investors and hedge funds held shares of Denali Therapeutics. The most heavily invested institutionals were Baillie Gifford & Co. ($164.36M), FMR LLC ($163.44M), Vanguard Group Inc. ($160.42M), Temasek Holdings Private Ltd ($156.02M), Wellington Management Group LLP ($155.11M), State Street Corp ($123.86M), and Capital Research Global Investors ($111.63M).Learn more on Denali Therapeutics' institutional investors. What percentage of Denali Therapeutics' stock is owned by institutional investors? 92.92% of Denali Therapeutics' stock is owned by institutional investors. Learn more on DNLI's institutional investor holdings. Which institutional investors have been buying Denali Therapeutics' stock? Of the 184 institutional investors that purchased Denali Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: FMR LLC ($7.78M), Norges Bank ($6.17M), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($4.64M), Capital Research Global Investors ($3.17M), Wellington Management Group LLP ($2.72M), Millennium Management LLC ($1.66M), and Vanguard Group Inc. ($1.57M). How much institutional buying is happening at Denali Therapeutics? Institutional investors have bought a total of 35,400,909 shares in the last 24 months. This purchase volume represents approximately $707.33M in transactions. Which of Denali Therapeutics' major shareholders have been selling company stock? Of the 87 institutional investors that sold Denali Therapeutics' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Capital Research Global Investors ($2.43M), Baillie Gifford & Co. ($1.67M), Marshall Wace LLP ($961.58K), Wellington Management Group LLP ($879.50K), Camber Capital Management LP ($850K), Point72 Asset Management L.P. ($719.62K), and Bank of New York Mellon Corp ($539.60K). How much institutional selling is happening at Denali Therapeutics? Institutional investors have sold a total of 13,325,450 shares in the last 24 months. This volume of shares sold represents approximately $258.72M in transactions. 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