| 11/19/2024 | Barclays PLC | 214,768 | $1.59M | 0.0% | +228.9% | 0.202% | |
| 11/16/2024 | Geode Capital Management LLC | 2,074,970 | $15.36M | 0.0% | +8.4% | 1.955% | |
| 11/15/2024 | Barclays PLC | 214,768 | $1.59M | 0.0% | +228.9% | 0.202% | |
| 11/15/2024 | Jane Street Group LLC | 138,728 | $1.03M | 0.0% | -61.2% | 0.131% | |
| 11/15/2024 | Wellington Management Group LLP | 319,045 | $2.36M | 0.0% | -10.8% | 0.301% | |
| 11/15/2024 | Sphera Funds Management LTD. | 536,547 | $3.97M | 0.6% | +1.9% | 0.506% | |
|
| 11/15/2024 | State Street Corp | 3,251,687 | $24.06M | 0.0% | +0.2% | 3.064% | |
| 11/15/2024 | Redmile Group LLC | 1,569,850 | $11.62M | 0.7% | -10.1% | 1.479% | |
| 11/15/2024 | Jacobs Levy Equity Management Inc. | 130,894 | $969K | 0.0% | +186.6% | 0.123% | |
| 11/15/2024 | Janus Henderson Group PLC | 15,158,218 | $112.14M | 0.1% | +14.2% | 14.283% | |
| 11/15/2024 | HighVista Strategies LLC | 66,787 | $494K | 0.2% | N/A | 0.063% | |
| 11/15/2024 | Erste Asset Management GmbH | 763,000 | $5.63M | 0.1% | N/A | 0.719% | |
| 11/14/2024 | PDT Partners LLC | 169,245 | $1.25M | 0.1% | N/A | 0.159% | |
| 11/14/2024 | Walleye Capital LLC | 435,298 | $3.22M | 0.0% | +1,232.2% | 0.410% | |
| 11/14/2024 | Suvretta Capital Management LLC | 7,991,644 | $59.14M | 1.9% | -0.5% | 7.530% | |
| 11/14/2024 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 140,998 | $1.04M | 0.0% | +1.2% | 0.133% | |
| 11/13/2024 | FMR LLC | 73,386 | $543K | 0.0% | +2,153.2% | 0.069% | |
| 11/13/2024 | Dynamic Technology Lab Private Ltd | 21,096 | $156K | 0.0% | -65.2% | 0.020% | |
| 11/12/2024 | Westfield Capital Management Co. LP | 3,006,038 | $22.25M | 0.1% | +29.6% | 3.056% | |
| 11/12/2024 | Algert Global LLC | 62,217 | $460K | 0.0% | +103.4% | 0.063% | |
| 11/12/2024 | Charles Schwab Investment Management Inc. | 721,050 | $5.34M | 0.0% | +8.1% | 0.733% | |
| 11/9/2024 | Intech Investment Management LLC | 21,566 | $160K | 0.0% | N/A | 0.022% | |
| 11/7/2024 | Quest Partners LLC | 22,074 | $163K | 0.0% | +172.1% | 0.022% | |
| 10/29/2024 | Harbor Capital Advisors Inc. | 227,930 | $1.69M | 0.1% | +165.3% | 0.232% | |
| 10/25/2024 | China Universal Asset Management Co. Ltd. | 20,370 | $151K | 0.0% | +76.2% | 0.021% | |
| 10/21/2024 | Gilliland Jeter Wealth Management LLC | 46,159 | $342K | 0.1% | +42.6% | 0.047% | |
| 10/10/2024 | Inspire Investing LLC | 56,112 | $415K | 0.0% | N/A | 0.057% | |
| 10/3/2024 | SG Americas Securities LLC | 30,713 | $227K | 0.0% | +21.4% | 0.031% | |
| 8/16/2024 | Northwestern Mutual Wealth Management Co. | 8,200 | $66K | 0.0% | N/A | 0.008% | |
| 8/16/2024 | Algert Global LLC | 30,587 | $245K | 0.0% | +30.8% | 0.031% | |
| 8/15/2024 | The Manufacturers Life Insurance Company | 31,355 | $251K | 0.0% | +12.8% | 0.032% | |
| 8/15/2024 | Millennium Management LLC | 1,010,352 | $8.09M | 0.0% | -7.1% | 1.027% | |
| 8/14/2024 | Squarepoint Ops LLC | 40,862 | $327K | 0.0% | N/A | 0.042% | |
| 8/14/2024 | Integral Health Asset Management LLC | 450,000 | $3.60M | 0.3% | +50.0% | 0.457% | |
| 8/14/2024 | ProShare Advisors LLC | 16,664 | $133K | 0.0% | -19.6% | 0.017% | |
| 8/14/2024 | Profund Advisors LLC | 27,100 | $217K | 0.0% | -62.2% | 0.028% | |
| 8/13/2024 | Orchard Capital Management LLC | 739,208 | $5.92M | 1.8% | -1.4% | 0.751% | |
| 8/12/2024 | XTX Topco Ltd | 31,978 | $256K | 0.0% | N/A | 0.033% | |
| 8/9/2024 | Renaissance Technologies LLC | 279,400 | $2.24M | 0.0% | N/A | 0.284% | |
| 8/8/2024 | American Century Companies Inc. | 63,864 | $512K | 0.0% | +219.0% | 0.065% | |
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| 8/6/2024 | Quest Partners LLC | 8,113 | $65K | 0.0% | +226.2% | 0.008% | |
| 8/6/2024 | Candriam S.C.A. | 848,079 | $6.79M | 0.0% | +173.6% | 0.862% | |
| 8/1/2024 | Rhumbline Advisers | 128,944 | $1.03M | 0.0% | +26.9% | 0.131% | |
| 7/26/2024 | Bank of New York Mellon Corp | 299,689 | $2.40M | 0.0% | +20.5% | 0.305% | |
| 7/19/2024 | Raymond James & Associates | 182,943 | $1.47M | 0.0% | +35.2% | 0.186% | |
| 7/12/2024 | SG Americas Securities LLC | 25,292 | $203K | 0.0% | N/A | 0.026% | |
| 7/9/2024 | Harbor Capital Advisors Inc. | 85,898 | $688K | 0.1% | +254.1% | 0.087% | |
| 5/17/2024 | RA Capital Management L.P. | 12,766,948 | $148.61M | 1.9% | +11.8% | 12.977% | |
| 5/17/2024 | Comerica Bank | 171,000 | $1.99M | 0.0% | +9.7% | 0.174% | |
| 5/16/2024 | Janus Henderson Group PLC | 12,603,382 | $146.65M | 0.1% | +41.4% | 12.811% | |
| 5/16/2024 | Redmile Group LLC | 2,264,566 | $26.36M | 1.0% | +15.0% | 2.302% | |
| 5/15/2024 | Bellevue Group AG | 13,700 | $159K | 0.0% | -32.2% | 0.014% | |
| 5/15/2024 | Price T Rowe Associates Inc. MD | 31,221 | $364K | 0.0% | +28.9% | 0.032% | |
| 5/15/2024 | University of Wisconsin Foundation | 498,137 | $5.80M | 6.5% | +293.7% | 0.506% | |
| 5/14/2024 | Natixis | 99,000 | $1.15M | 0.0% | N/A | 0.101% | |
| 5/14/2024 | American International Group Inc. | 38,968 | $454K | 0.0% | +22.4% | 0.040% | |
| 5/13/2024 | Ameritas Investment Partners Inc. | 7,886 | $92K | 0.0% | +28.4% | 0.008% | |
| 5/10/2024 | Vanguard Group Inc. | 4,722,971 | $54.98M | 0.0% | +9.6% | 4.960% | |
| 5/10/2024 | Westfield Capital Management Co. LP | 2,164,147 | $25.19M | 0.1% | +22.9% | 2.273% | |
| 5/8/2024 | Entropy Technologies LP | 27,154 | $316K | 0.0% | -19.0% | 0.029% | |
| 5/8/2024 | ProShare Advisors LLC | 20,737 | $241K | 0.0% | +34.5% | 0.022% | |
| 5/7/2024 | Swiss National Bank | 147,200 | $1.71M | 0.0% | +3.1% | 0.155% | |
| 5/1/2024 | Capstone Investment Advisors LLC | 103,767 | $1.21M | 0.0% | N/A | 0.109% | |
| 5/1/2024 | Mirae Asset Global Investments Co. Ltd. | 16,724 | $195K | 0.0% | -63.4% | 0.018% | |
| 4/29/2024 | Principal Financial Group Inc. | 10,614 | $124K | 0.0% | N/A | 0.011% | |
| 4/29/2024 | China Universal Asset Management Co. Ltd. | 17,900 | $208K | 0.0% | +104.6% | 0.018% | |
| 4/23/2024 | Wetzel Investment Advisors Inc. | 5,000 | $58K | 0.0% | +66.7% | 0.005% | |
| 4/23/2024 | Raymond James Financial Services Advisors Inc. | 117,305 | $1.37M | 0.0% | +12.5% | 0.123% | |
| 4/19/2024 | Bourgeon Capital Management LLC | 33,650 | $392K | 0.1% | -4.7% | 0.036% | |
| 3/27/2024 | Nomura Holdings Inc. | 82,000 | $916K | 0.0% | N/A | 0.088% | |
| 3/22/2024 | PNC Financial Services Group Inc. | 14,760 | $165K | 0.0% | +10.1% | 0.016% | |
| 3/5/2024 | Wellington Management Group LLP | 239,027 | $2.67M | 0.0% | N/A | 0.256% | |
| 2/23/2024 | Chicago Partners Investment Group LLC | 15,388 | $158K | 0.0% | +43.6% | 0.017% | |
| 2/15/2024 | Orchard Capital Management LLC | 739,208 | $8.26M | 2.6% | +36.2% | 0.793% | |
| 2/15/2024 | Parkman Healthcare Partners LLC | 219,448 | $2.45M | 0.3% | -39.6% | 0.235% | |
| 2/15/2024 | Parkwood LLC | 44,206 | $494K | 0.0% | +58.6% | 0.047% | |
| 2/15/2024 | Frazier Life Sciences Management L.P. | 2,000,000 | $22.34M | 1.2% | N/A | 2.146% | |
| 2/15/2024 | BVF Inc. IL | 4,047,354 | $45.21M | 1.1% | +119.2% | 4.342% | |
| 2/15/2024 | Comerica Bank | 155,930 | $1.74M | 0.0% | +205,071.1% | 0.167% | |
| 2/14/2024 | Pennant Investors LP | 44,500 | $497K | 0.1% | N/A | 0.048% | |
| 2/14/2024 | Superstring Capital Management LP | 1,021,477 | $11.41M | 8.1% | N/A | 1.096% | |
| 2/14/2024 | Bellevue Group AG | 20,200 | $226K | 0.0% | -48.5% | 0.022% | |
| 2/14/2024 | RTW Investments LP | 5,578,931 | $62.32M | 1.0% | N/A | 5.986% | |
| 2/13/2024 | Tower Research Capital LLC TRC | 4,800 | $54K | 0.0% | -52.2% | 0.005% | |
| 2/13/2024 | Rafferty Asset Management LLC | 453,674 | $5.07M | 0.0% | +18.8% | 0.487% | |
| 2/12/2024 | Eagle Asset Management Inc. | 702,095 | $7.84M | 0.0% | -1.5% | 0.753% | |
| 2/12/2024 | Monashee Investment Management LLC | 140,000 | $1.56M | 0.3% | N/A | 0.150% | |
| 2/9/2024 | Westfield Capital Management Co. LP | 1,761,148 | $19.67M | 0.1% | +34.2% | 1.890% | |
| 2/9/2024 | Quest Partners LLC | 10,465 | $117K | 0.0% | N/A | 0.011% | |
| 2/9/2024 | Dynamic Technology Lab Private Ltd | 38,545 | $431K | 0.0% | +104.9% | 0.041% | |
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| 2/7/2024 | Teacher Retirement System of Texas | 15,791 | $176K | 0.0% | +9.0% | 0.017% | |
| 2/7/2024 | E Fund Management Co. Ltd. | 24,363 | $272K | 0.0% | +24.2% | 0.026% | |
| 2/6/2024 | Charles Schwab Investment Management Inc. | 499,353 | $5.58M | 0.0% | +2.1% | 0.536% | |
| 2/6/2024 | AJOVista LLC | 3,789 | $42K | 0.1% | N/A | 0.004% | |
| 2/6/2024 | Swiss National Bank | 142,800 | $1.60M | 0.0% | +27.4% | 0.153% | |
| 2/5/2024 | Pekin Hardy Strauss Inc. | 14,385 | $161K | 0.0% | -30.8% | 0.015% | |
| 2/2/2024 | Gilliland Jeter Wealth Management LLC | 19,000 | $212K | 0.1% | N/A | 0.020% | |
| 2/1/2024 | New York State Common Retirement Fund | 26,041 | $291K | 0.0% | +4.8% | 0.028% | |
| 1/31/2024 | abrdn plc | 214,192 | $2.39M | 0.0% | N/A | 0.230% | |
| 1/31/2024 | Wetzel Investment Advisors Inc. | 3,000 | $34K | 0.0% | N/A | 0.003% | |
