Gyre Therapeutics (GYRE) Stock Price, News & Analysis

Company Overview

Gyre Therapeutics, Inc., a biopharmaceutical company, primarily focuses on the development and commercialization of Hydronidone for the treatment of Metabolic Dysfunction Associated Steatohepatitis in the United States. Its Hydronidone is also being evaluated for the treatment of liver fibrosis across a spectrum of chronic liver diseases. In addition, it advances a product pipeline in China, including Pirfenidone, for dermatomyositis interstitial lung disease, systemic sclerosis-associated interstitial lung disease, and pneumoconiosis, as well as for diabetic kidney disease; and product candidates for acute-on-chronic liver failure, chronic obstructive pulmonary disease, and pulmonary arterial hypertension. The company was founded in 2002 and is headquartered in San Diego, California.

Key Stats

• Today's Range: $8.06 to $8.30
• 50-Day Range: $6.65 to $9.00
• 52-Week Range: $6.11 to $19.00
• Volume: 55,912 shs
• Average Volume: 167,729 shs
• Market Capitalization: $791.67 million
• P/E Ratio: 822.82
• Dividend Yield: N/A
• Price Target: N/A
• Consensus Rating: Buy

Gyre Therapeutics Stock Analysis - MarketRank™

Gyre Therapeutics scored higher than 2% of companies evaluated by MarketBeat, and ranked 935th out of 936 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: N/A
• Analyst Rating: N/A

Consensus Rating

There is not enough analysis data for Gyre Therapeutics.

Earnings and Valuation

• Score: 0.0 / 5
• Proj. Earnings Growth: N/A

Price to Earnings Ratio vs. the Market

The P/E ratio of Gyre Therapeutics is 825.33, which means that it is trading at a more expensive P/E ratio than the market average P/E ratio of about 28.51.

Price to Earnings Ratio vs. Sector

The P/E ratio of Gyre Therapeutics is 825.33, which means that it is trading at a more expensive P/E ratio than the Medical sector average P/E ratio of about 30.21.

Price to Book Value per Share Ratio

Gyre Therapeutics has a P/B Ratio of 6.14. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.

Short Interest

• Score: 1.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

11.38% of the float of Gyre Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Gyre Therapeutics has a short interest ratio ("days to cover") of 8.6.

Change versus previous month

Short interest in Gyre Therapeutics has recently increased by 2.21%, indicating that investor sentiment is decreasing.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Gyre Therapeutics does not currently pay a dividend.

Dividend Growth

Gyre Therapeutics does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

11.38% of the float of Gyre Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Gyre Therapeutics has a short interest ratio ("days to cover") of 8.6.

Change versus previous month

Short interest in Gyre Therapeutics has recently increased by 2.21%, indicating that investor sentiment is decreasing.

News and Social Media

• Score: 1.7 / 5
• News Sentiment: 0.13

News Sentiment

Gyre Therapeutics has a news sentiment score of 0.13. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.65 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 10 news articles for Gyre Therapeutics this week, compared to 2 articles on an average week.

Company Ownership

• Score: 0.8 / 5
• Insider Trading: Selling Shares

Insider Buying vs. Insider Selling

In the past three months, Gyre Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $23,804.00 in company stock.

Percentage Held by Insiders

Only 10.00% of the stock of Gyre Therapeutics is held by insiders.

Percentage Held by Institutions

Only 23.99% of the stock of Gyre Therapeutics is held by institutions.

GYRE Stock Analysis - Frequently Asked Questions

How have GYRE shares performed this year?

Gyre Therapeutics' stock was trading at $12.10 at the beginning of 2025. Since then, GYRE stock has decreased by 32.0% and is now trading at $8.23.

How were Gyre Therapeutics' earnings last quarter?

Gyre Therapeutics, Inc. (NASDAQ:GYRE) announced its quarterly earnings results on Monday, August, 11th. The company reported $0.02 earnings per share for the quarter, missing analysts' consensus estimates of $0.03 by $0.01. The firm earned $26.77 million during the quarter, compared to analyst estimates of $30.80 million. Gyre Therapeutics had a trailing twelve-month return on equity of 7.67% and a net margin of 4.08%.

Who are Gyre Therapeutics' major shareholders?

Top institutional shareholders of Gyre Therapeutics include Geode Capital Management LLC (0.43%), SBI Securities Co. Ltd. (0.25%), American Century Companies Inc. (0.01%) and JPMorgan Chase & Co. (0.01%). Insiders that own company stock include Songjiang Ma and Nassim Usman.
View institutional ownership trends.

How do I buy shares of Gyre Therapeutics?

Shares of GYRE stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Gyre Therapeutics own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Gyre Therapeutics investors own include NVIDIA (NVDA), Meta Platforms (META), Advanced Micro Devices (AMD), Netflix (NFLX), Broadcom (AVGO), Palo Alto Networks (PANW) and Invesco QQQ (QQQ).

Company Calendar

• Last Earnings: 8/11/2025
• Today: 8/14/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:GYRE
• Previous Symbol: NASDAQ:GYRE
• CIK: 1124105
• Web: www.catalystbiosciences.com
• Phone: (619) 949-3681
• Fax: 336-480-2107
• Employees: 40
• Year Founded: N/A

Profitability

• EPS (Trailing Twelve Months): $0.01
• Trailing P/E Ratio: 806.31
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: $12.09 million
• Net Margins: 4.08%
• Pretax Margin: 11.33%
• Return on Equity: 7.67%
• Return on Assets: 6.19%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 5.40
• Quick Ratio: 3.19

Sales & Book Value

• Annual Sales: $105.76 million
• Price / Sales: 7.34
• Cash Flow: $0.21 per share
• Price / Cash Flow: 38.28
• Book Value: $1.34 per share
• Price / Book: 6.01

Miscellaneous

• Outstanding Shares: 96,310,000
• Free Float: 84,382,000
• Market Cap: $775.78 million
• Optionable: No Data
• Beta: 1.80