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Hyperion DeFi (HYPD) Competitors

Hyperion DeFi logo
$14.98 +2.99 (+24.94%)
As of 09/12/2025 04:00 PM Eastern

HYPD vs. MEIP, IVVD, HURA, CGEN, GNLX, MGNX, ZNTL, PLX, BHST, and IKT

Should you be buying Hyperion DeFi stock or one of its competitors? The main competitors of Hyperion DeFi include MEI Pharma (MEIP), Invivyd (IVVD), TuHURA Biosciences (HURA), Compugen (CGEN), Genelux (GNLX), MacroGenics (MGNX), Zentalis Pharmaceuticals (ZNTL), Protalix BioTherapeutics (PLX), BioHarvest Sciences (BHST), and Inhibikase Therapeutics (IKT). These companies are all part of the "pharmaceutical products" industry.

Hyperion DeFi vs. Its Competitors

MEI Pharma (NASDAQ:MEIP) and Hyperion DeFi (NASDAQ:HYPD) are both small-cap medical companies, but which is the better business? We will compare the two businesses based on the strength of their risk, analyst recommendations, earnings, media sentiment, dividends, profitability, institutional ownership and valuation.

Hyperion DeFi has a consensus price target of $2.00, indicating a potential downside of 86.65%. Given Hyperion DeFi's stronger consensus rating and higher probable upside, analysts plainly believe Hyperion DeFi is more favorable than MEI Pharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
MEI Pharma
0 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
0.00
Hyperion DeFi
0 Sell rating(s)
4 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
2.00

MEI Pharma has higher earnings, but lower revenue than Hyperion DeFi. MEI Pharma is trading at a lower price-to-earnings ratio than Hyperion DeFi, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
MEI PharmaN/AN/A$17.78M-$4.75-0.67
Hyperion DeFi$44.44K1,919.78-$49.82M-$58.40-0.26

MEI Pharma has a net margin of 0.00% compared to Hyperion DeFi's net margin of -62,238.41%. MEI Pharma's return on equity of -77.00% beat Hyperion DeFi's return on equity.

Company Net Margins Return on Equity Return on Assets
MEI PharmaN/A -77.00% -64.79%
Hyperion DeFi -62,238.41%-876.25%-181.67%

52.4% of MEI Pharma shares are held by institutional investors. Comparatively, 25.8% of Hyperion DeFi shares are held by institutional investors. 3.1% of MEI Pharma shares are held by company insiders. Comparatively, 10.9% of Hyperion DeFi shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

MEI Pharma has a beta of 0.38, meaning that its share price is 62% less volatile than the S&P 500. Comparatively, Hyperion DeFi has a beta of 2.5, meaning that its share price is 150% more volatile than the S&P 500.

In the previous week, Hyperion DeFi had 1 more articles in the media than MEI Pharma. MarketBeat recorded 6 mentions for Hyperion DeFi and 5 mentions for MEI Pharma. Hyperion DeFi's average media sentiment score of 0.36 beat MEI Pharma's score of 0.19 indicating that Hyperion DeFi is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
MEI Pharma
0 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Hyperion DeFi
0 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Hyperion DeFi beats MEI Pharma on 8 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding HYPD and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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HYPD vs. The Competition

MetricHyperion DeFiBiotechnology IndustryMedical SectorNASDAQ Exchange
Market Cap$68.28M$236.97M$5.87B$10.13B
Dividend YieldN/A3.78%5.68%4.60%
P/E Ratio-0.2641.0874.5225.93
Price / Sales1,919.785,000.68516.43181.21
Price / CashN/A13.1937.5660.44
Price / Book-0.02103.7512.166.29
Net Income-$49.82M-$90.99M$3.28B$270.77M
7 Day Performance143.97%2.70%0.78%3.84%
1 Month Performance112.78%21.05%4.87%4.85%
1 Year Performance-65.11%530.95%60.72%26.00%

Hyperion DeFi Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
HYPD
Hyperion DeFi
0.4095 of 5 stars
$14.98
+24.9%
$2.00
-86.6%
-65.5%$68.28M$44.44K-0.2640Gap Up
High Trading Volume
MEIP
MEI Pharma
1.3182 of 5 stars
$3.00
-29.1%
N/A+4.2%$138.91MN/A-0.63100Upcoming Earnings
Gap Up
High Trading Volume
IVVD
Invivyd
3.5298 of 5 stars
$1.16
+1.8%
$3.18
+174.4%
+24.3%$136.96M$25.38M-1.26100Short Interest ↑
HURA
TuHURA Biosciences
1.8924 of 5 stars
$2.52
-1.2%
$12.67
+402.6%
N/A$127.62MN/A0.00N/APositive News
CGEN
Compugen
1.7285 of 5 stars
$1.45
+1.4%
$4.00
+175.9%
-31.6%$127.61M$27.86M-6.5970
GNLX
Genelux
1.5728 of 5 stars
$3.56
+5.6%
$20.33
+471.2%
+47.9%$127.30M$10K-4.1410Positive News
High Trading Volume
MGNX
MacroGenics
4.4746 of 5 stars
$1.76
-12.0%
$3.60
+104.5%
-56.0%$126.41M$149.96M-3.09430
ZNTL
Zentalis Pharmaceuticals
1.879 of 5 stars
$1.63
-6.9%
$8.20
+403.1%
-52.7%$126.24M$67.43M-0.72160Positive News
PLX
Protalix BioTherapeutics
2.5435 of 5 stars
$1.58
+2.6%
$15.00
+849.4%
+70.8%$125.98M$61.95M-12.15200High Trading Volume
BHST
BioHarvest Sciences
2.4465 of 5 stars
$7.14
-5.9%
$13.67
+91.4%
N/A$124.67M$25.19M-10.20N/AGap Up
IKT
Inhibikase Therapeutics
0.0049 of 5 stars
$1.66
-0.6%
N/AN/A$124.44M$260K0.006

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This page (NASDAQ:HYPD) was last updated on 9/13/2025 by MarketBeat.com Staff
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