| 2/17/2025 | OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC | 625,589 | $1.55M | 0.1% | -21.6% | 1.062% | |
| 2/17/2025 | Cubist Systematic Strategies LLC | 22,437 | $55K | 0.0% | N/A | 0.038% | |
| 2/14/2025 | Schonfeld Strategic Advisors LLC | 10,344 | $26K | 0.0% | -42.9% | 0.018% | |
| 2/14/2025 | Northern Trust Corp | 666,845 | $1.65M | 0.0% | +1,933.1% | 1.133% | |
| 2/14/2025 | Two Sigma Securities LLC | 11,461 | $28K | 0.0% | N/A | 0.019% | |
| 2/14/2025 | Eversept Partners LP | 492,452 | $1.22M | 0.1% | -69.6% | 0.836% | |
| 2/13/2025 | Walleye Capital LLC | 20,691 | $51K | 0.0% | N/A | 0.035% | |
| 2/13/2025 | Raymond James Financial Inc. | 638,092 | $1.58M | 0.0% | N/A | 1.084% | |
| 2/12/2025 | Geode Capital Management LLC | 48,136 | $119K | 0.0% | +32.8% | 0.082% | |
| 2/10/2025 | Commonwealth Equity Services LLC | 111,500 | $275K | 0.0% | +20.5% | 0.189% | |
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| 2/6/2025 | Raymond James Financial Inc. | 638,092 | $1.58M | 0.0% | N/A | 1.084% | |
| 8/14/2024 | Marshall Wace LLP | 33,824 | $59K | 0.0% | -58.7% | 0.057% | |
| 5/17/2024 | Ikarian Capital LLC | 704,987 | $1.09M | 0.1% | +2.4% | 1.197% | |
| 2/13/2024 | Affinity Asset Advisors LLC | 200,097 | $326K | 0.1% | -38.5% | 0.448% | |
| 1/18/2024 | Franklin Street Advisors Inc. NC | 75,100 | $122K | 0.0% | +49.9% | 0.168% | |
| 1/16/2024 | Raymond James Financial Services Advisors Inc. | 317,859 | $518K | 0.0% | +18.2% | 0.711% | |
| 1/16/2024 | Raymond James & Associates | 175,279 | $286K | 0.0% | +7.9% | 0.392% | |
| 11/15/2023 | Alps Advisors Inc. | 83,279 | $248K | 0.0% | +109.4% | 0.186% | |
| 11/15/2023 | Affinity Asset Advisors LLC | 325,097 | $969K | 0.3% | +35.3% | 0.727% | |
| 11/14/2023 | 683 Capital Management LLC | 2,350,000 | $7.00M | 0.5% | +17.5% | 5.257% | |
| 10/24/2023 | Raymond James Financial Services Advisors Inc. | 268,915 | $801K | 0.0% | +45.6% | 0.602% | |
| 10/24/2023 | Raymond James & Associates | 162,406 | $484K | 0.0% | +18.5% | 0.363% | |
| 8/21/2023 | Affinity Asset Advisors LLC | 240,200 | $1.07M | 0.4% | N/A | 0.537% | |
| 8/15/2023 | Suvretta Capital Management LLC | 5,733,910 | $25.57M | 1.4% | +167.2% | 12.828% | |
| 8/14/2023 | 683 Capital Management LLC | 2,000,000 | $8.92M | 0.6% | N/A | 4.474% | |
| 8/14/2023 | Prelude Capital Management LLC | 45,241 | $202K | 0.0% | N/A | 0.101% | |
| 8/11/2023 | Velan Capital Investment Management LP | 200,000 | $892K | 0.8% | N/A | 0.447% | |
| 7/25/2023 | Raymond James Financial Services Advisors Inc. | 184,737 | $824K | 0.0% | +19.6% | 0.413% | |
| 7/25/2023 | Raymond James & Associates | 137,056 | $611K | 0.0% | +144.5% | 0.307% | |
| 7/13/2023 | Franklin Street Advisors Inc. NC | 50,100 | $223K | 0.0% | -33.3% | 0.112% | |
| 4/14/2023 | Raymond James Financial Services Advisors Inc. | 154,405 | $300K | 0.0% | +16.6% | 0.349% | |
| 4/14/2023 | Raymond James & Associates | 56,065 | $109K | 0.0% | +36.3% | 0.127% | |
| 2/8/2023 | Raymond James Financial Services Advisors Inc. | 132,475 | $411K | 0.0% | +19.0% | 0.300% | |
| 1/31/2023 | Kestra Advisory Services LLC | 15,700 | $49K | 0.0% | +42.7% | 0.036% | |
| 1/12/2023 | Marquette Asset Management LLC | 29,206 | $91K | 0.0% | -50.6% | 0.066% | |
| 11/9/2022 | Group One Trading L.P. | 16,047 | $42K | 0.0% | N/A | 0.036% | |
| 10/25/2022 | Raymond James & Associates | 43,423 | $115K | 0.0% | +11.1% | 0.098% | |
| 10/25/2022 | Raymond James Financial Services Advisors Inc. | 111,287 | $294K | 0.0% | -22.2% | 0.252% | |
| 10/6/2022 | Marquette Asset Management LLC | 59,160 | $156K | 0.0% | -24.8% | 0.134% | |
| 7/19/2022 | Commonwealth Equity Services LLC | 92,600 | $134K | 0.0% | -7.5% | 0.210% | |
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| 7/15/2022 | Marquette Asset Management LLC | 78,620 | $114K | 0.0% | +136.7% | 0.178% | |
| 7/12/2022 | FNY Investment Advisers LLC | 80,000 | $116K | 0.1% | -20.0% | 0.181% | |
| 5/4/2022 | Commonwealth Equity Services LLC | 100,100 | $183K | 0.0% | +891.1% | 0.226% | |
| 3/3/2022 | Walleye Capital LLC | 530,432 | $2.53M | 0.1% | N/A | 1.227% | |
| 2/15/2022 | Sofinnova Investments Inc. | 1,161,736 | $5.53M | 0.3% | N/A | 2.687% | |
| 2/15/2022 | Kingdon Capital Management L.L.C. | 325,000 | $1.55M | 0.2% | -18.8% | 0.752% | |
| 2/8/2022 | Raymond James Financial Services Advisors Inc. | 95,674 | $455K | 0.0% | +588.9% | 0.221% | |
| 2/8/2022 | Raymond James & Associates | 65,542 | $312K | 0.0% | +529.1% | 0.152% | |
| 2/1/2022 | FNY Investment Advisers LLC | 100,000 | $476K | 0.3% | -68.6% | 0.231% | |
| 1/31/2022 | Commonwealth Equity Services LLC | 10,100 | $48K | 0.0% | N/A | 0.023% | |
| 1/10/2022 | FNY Investment Advisers LLC | 100,000 | $476K | 0.3% | -68.6% | 0.231% | |
| 11/16/2021 | Two Sigma Securities LLC | 22,553 | $58K | 0.0% | N/A | 0.052% | |
| 11/15/2021 | Great Point Partners LLC | 551,918 | $1.43M | 0.3% | -74.9% | 1.277% | |
| 11/2/2021 | Raymond James Financial Services Advisors Inc. | 13,888 | $36K | 0.0% | -40.5% | 0.032% | |
| 11/2/2021 | Raymond James & Associates | 10,419 | $27K | 0.0% | -47.7% | 0.024% | |
| 10/13/2021 | FNY Investment Advisers LLC | 318,000 | $823K | 0.4% | -7.3% | 0.736% | |
| 8/18/2021 | Ikarian Capital LLC | 666,596 | $1.98M | 0.2% | -4.7% | 1.542% | |
| 8/17/2021 | Boothbay Fund Management LLC | 84,900 | $252K | 0.0% | -4.7% | 0.196% | |
| 8/13/2021 | Renaissance Technologies LLC | 134,283 | $399K | 0.0% | +8.9% | 0.311% | |
| 8/13/2021 | Altium Capital Management LP | 161,206 | $479K | 0.1% | -79.2% | 0.373% | |
| 8/13/2021 | Algert Global LLC | 23,010 | $68K | 0.0% | -33.6% | 0.053% | |
| 8/13/2021 | IPG Investment Advisors LLC | 25,900 | $77K | 0.0% | N/A | 0.060% | |
| 8/5/2021 | GSA Capital Partners LLP | 46,633 | $139K | 0.0% | N/A | 0.108% | |
| 7/19/2021 | Marquette Asset Management LLC | 33,215 | $99K | 0.0% | N/A | 0.077% | |
| 5/20/2021 | Axiom Investment Management LLC | 73,700 | $289K | 0.1% | N/A | 0.170% | |
| 5/18/2021 | Baker BROS. Advisors LP | 138,040 | $538K | 0.0% | -83.9% | 0.319% | |
| 5/18/2021 | Millennium Management LLC | 30,515 | $119K | 0.0% | N/A | 0.071% | |
| 5/18/2021 | Verition Fund Management LLC | 116,695 | $455K | 0.0% | +16.7% | 0.270% | |
| 5/18/2021 | Morgan Stanley | 720,977 | $2.81M | 0.0% | +2.1% | 1.668% | |
| 5/18/2021 | Orbimed Advisors LLC | 1,064,118 | $4.15M | 0.0% | +91.4% | 2.462% | |
| 5/18/2021 | Great Point Partners LLC | 2,200,000 | $8.58M | 1.8% | N/A | 5.089% | |
| 5/18/2021 | Alyeska Investment Group L.P. | 150,000 | $585K | 0.0% | N/A | 0.347% | |
| 5/17/2021 | Suvretta Capital Management LLC | 3,285,000 | $12.81M | 0.2% | N/A | 7.599% | |
| 5/17/2021 | DAFNA Capital Management LLC | 600,000 | $2.34M | 0.6% | N/A | 1.388% | |
| 5/17/2021 | Sphera Funds Management LTD. | 1,000,000 | $3.90M | 0.3% | N/A | 2.313% | |
| 5/17/2021 | Ikarian Capital LLC | 699,750 | $2.73M | 0.1% | +367.3% | 1.619% | |
| 5/14/2021 | Laurion Capital Management LP | 500,000 | $1.95M | 0.0% | N/A | 1.157% | |
| 5/14/2021 | Occudo Quantitative Strategies LP | 11,077 | $43K | 0.0% | -38.1% | 0.026% | |
| 5/14/2021 | Algert Global LLC | 34,640 | $135K | 0.0% | N/A | 0.080% | |
| 5/13/2021 | Eversept Partners LP | 268,634 | $1.05M | 0.1% | N/A | 0.621% | |
| 5/13/2021 | QS Investors LLC | 174,200 | $679K | 0.0% | N/A | 0.403% | |
| 5/13/2021 | Axiom Investment Management LLC | 73,700 | $289K | 0.1% | N/A | 0.170% | |
| 5/13/2021 | Renaissance Technologies LLC | 123,347 | $481K | 0.0% | -10.7% | 0.285% | |
| 5/12/2021 | UBS Group AG | 6,529 | $25K | 0.0% | +235.5% | 0.015% | |
| 5/12/2021 | Granite Point Capital Management L.P. | 381,086 | $1.49M | 0.1% | N/A | 0.882% | |
| 5/7/2021 | BlackRock Inc. | 7,419 | $29K | 0.0% | +77.7% | 0.017% | |
| 5/6/2021 | Altium Capital Management LP | 774,600 | $3.02M | 0.8% | N/A | 1.792% | |
| 5/4/2021 | Franklin Street Advisors Inc. NC | 75,100 | $293K | 0.0% | +199.2% | 0.174% | |
| 4/21/2021 | Personal CFO Solutions LLC | 13,000 | $51K | 0.0% | -18.2% | 0.030% | |
| 4/8/2021 | Pacifica Partners Inc. | 12,585 | $48K | 0.0% | +247.2% | 0.029% | |
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| 2/24/2021 | Bank Julius Baer & Co. Ltd Zurich | 197,614 | $994K | 0.0% | N/A | 0.752% | |
| 2/19/2021 | JPMorgan Chase & Co. | 17,200 | $87K | 0.0% | N/A | 0.065% | |
| 2/18/2021 | Verition Fund Management LLC | 100,000 | $503K | 0.0% | +11.1% | 0.381% | |
| 2/12/2021 | Raymond James Financial Services Advisors Inc. | 33,144 | $167K | 0.0% | -30.9% | 0.126% | |
| 2/10/2021 | Renaissance Technologies LLC | 138,100 | $695K | 0.0% | N/A | 0.526% | |
