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Ionis Pharmaceuticals (IONS) Financials

Ionis Pharmaceuticals logo
$29.57 +0.47 (+1.62%)
As of 04/24/2025 04:00 PM Eastern
Annual Income Statements for Ionis Pharmaceuticals

Annual Income Statements for Ionis Pharmaceuticals

This table shows Ionis Pharmaceuticals' income and expenses over time, based on annual financial data. All values are USD millions unless otherwise specified.

Metric 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024
Net Income / (Loss) Attributable to Common Shareholders
-88 -60 0.35 274 278 -444 -29 -270 -366 -454
Consolidated Net Income / (Loss)
-88 -60 -11 215 287 -480 -29 -270 -366 -454
Net Income / (Loss) Continuing Operations
-88 -60 -11 215 287 -480 -29 -270 -366 -453
Total Pre-Tax Income
-88 -57 -17 -76 339 -135 -29 -258 -334 -460
Total Operating Income
-76 -20 31 -61 366 -172 -30 -410 -354 -475
Total Gross Profit
284 373 514 598 1,118 717 800 573 779 694
Total Revenue
284 373 514 600 1,123 729 810 587 788 705
Operating Revenue
284 373 514 600 1,123 729 810 587 788 705
Total Cost of Revenue
0.00 0.00 0.00 1.82 4.38 12 11 14 9.13 11
Operating Cost of Revenue
- 0.00 0.00 1.82 4.38 12 11 14 9.13 11
Total Operating Expenses
359 393 483 659 752 889 830 983 1,132 1,169
Selling, General & Admin Expense
37 49 108 245 287 354 186 150 233 267
Research & Development Expense
322 344 375 415 466 535 643 833 900 902
Total Other Income / (Expense), net
-12 -37 -48 -15 -27 38 1.04 152 20 14
Interest Expense
37 43 45 45 79 9.51 9.35 8.12 81 90
Interest & Investment Income
25 5.47 8.18 30 52 47 20 18 87 104
Other Income / (Expense), net
0.00 0.00 -11 -0.18 -0.69 -0.06 -9.76 142 14 -0.01
Income Tax Expense
0.37 2.93 -5.98 -291 52 345 -0.55 12 32 -6.17
Other Gains / (Losses), net
- - - - - - - - - 1.34
Basic Earnings per Share
($0.74) ($0.50) $0.15 $2.09 $2.00 ($3.18) ($0.20) ($1.90) ($2.56) ($3.04)
Weighted Average Basic Shares Outstanding
119.72M 120.93M 124.02M 132.32M 140.00M 139.61M 141.02M 141.85M 143.19M 149.51M
Diluted Earnings per Share
($0.74) ($0.50) $0.15 $2.07 $1.90 ($3.18) ($0.20) ($1.90) ($2.56) ($3.04)
Weighted Average Diluted Shares Outstanding
119.72M 120.93M 126.10M 134.06M 153.16M 139.61M 141.02M 141.85M 143.19M 149.51M
Weighted Average Basic & Diluted Shares Outstanding
119.72M 120.20M 4.30M 131M 138.70M 140.86M 141.69M 142.95M 145.75M 158.96M

Quarterly Income Statements for Ionis Pharmaceuticals

This table shows Ionis Pharmaceuticals' income and expenses over time, based on quarterly financial data. All values are USD millions unless otherwise specified.

Metric Q3 2022 Q4 2022 Q1 2023 Q2 2023 Q3 2023 Q4 2023 Q1 2024 Q2 2024 Q3 2024 Q4 2024
Net Income / (Loss) Attributable to Common Shareholders
-47 -52 -124 -85 -147 -9.26 -143 -66 -140 -104
Consolidated Net Income / (Loss)
-47 -52 -124 -85 -147 -9.26 -143 -66 -140 -104
Net Income / (Loss) Continuing Operations
-47 -52 -124 -85 -147 -9.26 -143 -66 -140 -103
Total Pre-Tax Income
-47 -44 -113 -77 -141 -2.77 -143 -66 -144 -107
Total Operating Income
-59 -208 -114 -90 -143 -6.12 -150 -66 -149 -111
Total Gross Profit
158 148 129 186 142 321 117 221 133 223
Total Revenue
160 152 131 188 144 325 119 225 134 227
Operating Revenue
160 152 131 188 144 325 119 225 134 227
Total Cost of Revenue
1.52 3.69 1.34 2.54 2.19 3.06 2.15 4.16 1.07 3.83
Operating Cost of Revenue
1.52 3.69 1.34 2.54 2.19 3.06 2.15 4.16 1.07 3.83
Total Operating Expenses
217 356 243 276 285 328 267 287 281 334
Selling, General & Admin Expense
34 48 46 46 70 71 53 65 62 88
Research & Development Expense
183 308 198 230 215 257 214 222 220 245
Total Other Income / (Expense), net
12 164 1.21 13 2.46 3.36 6.79 -0.11 4.56 2.44
Interest Expense
2.14 1.73 17 20 22 22 22 23 23 23
Interest & Investment Income
9.87 16 18 22 22 26 29 22 27 26
Other Income / (Expense), net
4.71 150 0.23 11 2.45 0.24 0.28 0.61 0.14 -1.04
Income Tax Expense
0.28 8.10 11 7.84 6.60 6.50 0.08 0.06 -3.62 -2.69
Basic Earnings per Share
($0.33) ($0.37) ($0.87) ($0.60) ($1.03) ($0.06) ($0.98) ($0.45) ($0.95) ($0.66)
Weighted Average Basic Shares Outstanding
141.95M 141.85M 142.74M 143.10M 143.32M 143.19M 145.54M 145.96M 148.59M 149.51M
Diluted Earnings per Share
($0.33) ($0.37) ($0.87) ($0.60) ($1.03) ($0.06) ($0.98) ($0.45) ($0.95) ($0.66)
Weighted Average Diluted Shares Outstanding
141.95M 141.85M 142.74M 143.10M 143.32M 143.19M 145.54M 145.96M 148.59M 149.51M
Weighted Average Basic & Diluted Shares Outstanding
142.05M 142.95M 143.09M 143.33M 143.47M 145.75M 145.97M 146.21M 157.90M 158.96M

Annual Cash Flow Statements for Ionis Pharmaceuticals

This table details how cash moves in and out of Ionis Pharmaceuticals' business through operations, investing, and financing, using annual figures. All values are USD millions unless otherwise specified.

Metric 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024
Net Change in Cash & Equivalents
-14 -44 45 149 404 -286 472 -593 123 -157
Net Cash From Operating Activities
21 -112 174 603 346 36 31 -274 -308 -501
Net Cash From Continuing Operating Activities
21 -112 174 603 346 36 31 -274 -308 -501
Net Income / (Loss) Continuing Operations
-88 -60 -11 215 287 -480 -29 -270 -366 -454
Consolidated Net Income / (Loss)
-88 -60 -11 215 287 -480 -29 -270 -366 -454
Depreciation Expense
6.98 7.48 6.71 11 13 13 15 14 10 9.61
Amortization Expense
41 40 45 36 -1.09 19 27 21 -10 -19
Non-Cash Adjustments To Reconcile Net Income
41 78 97 180 215 202 131 -47 136 171
Changes in Operating Assets and Liabilities, net
20 -178 37 161 -168 281 -114 7.57 -77 -209
Net Cash From Investing Activities
-60 57 -358 -930 -41 274 195 -263 -214 -134
Net Cash From Continuing Investing Activities
-60 57 -358 -930 -41 274 195 -263 -214 -134
Purchase of Property, Plant & Equipment
-12 -12 -38 -18 -31 -35 -12 -16 -24 -45
Acquisitions
- - - - -5.38 -5.93 -5.95 -4.38 -4.21 -5.06
Purchase of Investments
-493 -301 -880 -1,795 -1,957 -1,570 -1,131 -1,486 -1,771 -1,853
Sale of Property, Plant & Equipment
- - - - - 0.00 0.00 254 0.02 0.00
Sale and/or Maturity of Investments
420 365 557 883 1,952 1,886 1,344 989 1,585 1,769
Net Cash From Financing Activities
25 11 229 476 100 -597 246 -55 644 478
Net Cash From Continuing Financing Activities
25 11 229 476 100 -597 246 -55 644 478
Repayment of Debt
-9.06 -7.07 -3.60 0.00 -23 0.00 -335 -51 -502 -45
Issuance of Debt
8.50 4.00 60 0.00 110 0.00 633 0.00 575 0.00
Issuance of Common Equity
25 13 255 476 176 52 101 6.37 49 523
Other Financing Activities, net
0.40 1.86 -80 0.00 -128 -13 -153 -11 522 0.00
Effect of Exchange Rate Changes
- - - -0.02 0.09 0.62 - - 0.35 -0.27
Cash Interest Paid
6.80 7.31 8.04 9.59 9.87 6.25 4.78 2.90 6.51 11
Cash Income Taxes Paid
- - 0.00 0.00 9.04 26 0.04 5.01 48 -5.62

Quarterly Cash Flow Statements for Ionis Pharmaceuticals

This table details how cash moves in and out of Ionis Pharmaceuticals' business through operations, investing, and financing, using quarterly figures. All values are USD millions unless otherwise specified.

Metric Q3 2022 Q4 2022 Q1 2023 Q2 2023 Q3 2023 Q4 2023 Q1 2024 Q2 2024 Q3 2024 Q4 2024
Net Change in Cash & Equivalents
-207 -39 33 116 -73 47 -50 -55 41 -93
Net Cash From Operating Activities
-24 -200 -134 -97 -109 33 -150 -120 -115 -116
Net Cash From Continuing Operating Activities
-24 -200 -134 -97 -109 33 -150 -120 -115 -116
Net Income / (Loss) Continuing Operations
-47 -52 -124 -85 -147 -9.26 -143 -66 -140 -104
Consolidated Net Income / (Loss)
-47 -52 -124 -85 -147 -9.26 -143 -66 -140 -104
Depreciation Expense
3.82 3.03 2.60 2.62 2.52 2.54 2.55 2.47 2.36 2.24
Amortization Expense
3.83 3.66 -0.55 -2.89 -3.15 -3.76 -4.49 -5.10 -4.33 -4.75
Non-Cash Adjustments To Reconcile Net Income
-31 -124 43 18 45 30 40 43 36 52
Changes in Operating Assets and Liabilities, net
46 -31 -55 -29 -5.93 13 -46 -94 -8.46 -61
Net Cash From Investing Activities
-184 212 -326 70 69 -27 76 62 -341 68
Net Cash From Continuing Investing Activities
-184 212 -326 70 69 -27 76 62 -341 68
Purchase of Property, Plant & Equipment
-5.54 -4.14 -10 -12 -2.14 0.82 -4.49 -6.23 -9.06 -25
Acquisitions
-1.52 -0.87 -1.25 -1.06 -1.10 -0.79 -1.24 -14 13 -2.55
Purchase of Investments
-561 -262 -688 -244 -421 -418 -519 -285 -715 -334
Sale and/or Maturity of Investments
384 225 374 327 493 391 601 368 371 430
Net Cash From Financing Activities
1.83 -51 492 144 -32 41 24 2.56 496 -44
Net Cash From Continuing Financing Activities
1.83 -51 492 144 -32 41 24 2.56 496 -44
Repayment of Debt
-0.09 -51 -0.04 -434 -68 -0.04 -0.04 -0.04 -0.05 -45
Issuance of Common Equity
2.57 0.34 2.56 2.39 3.73 41 24 2.60 496 0.43
Cash Interest Paid
0.66 0.69 0.09 0.44 0.42 5.56 0.10 5.47 0.15 5.16
Cash Income Taxes Paid
- 5.01 0.29 0.22 0.20 48 0.01 1.98 0.08 -7.69

Annual Balance Sheets for Ionis Pharmaceuticals

This table presents Ionis Pharmaceuticals' assets and liabilities at the end of each period, using annual balance sheet data. All values are USD millions unless otherwise specified.

Metric 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024
Total Assets
948 912 1,323 2,668 3,233 2,390 2,612 2,534 2,990 3,004
Total Current Assets
837 798 1,169 2,208 2,721 2,131 2,345 2,203 2,642 2,620
Cash & Equivalents
129 85 130 279 683 398 869 276 399 242
Short-Term Investments
675 581 893 1,805 1,816 1,495 1,246 1,710 1,932 2,056
Inventories, net
6.90 7.49 9.98 8.58 18 22 25 22 7.44 13
Other Current Assets
15 17 136 115 203 216 205 194 303 310
Plant, Property, & Equipment, net
90 93 122 132 154 181 178 74 71 94
Total Noncurrent Assets
21 22 32 328 359 78 89 257 277 289
Other Noncurrent Operating Assets
1.35 1.33 10 13 28 50 89 257 277 289
Total Liabilities & Shareholders' Equity
948 912 1,323 2,668 3,233 2,390 2,612 2,534 2,990 3,004
Total Liabilities
747 813 957 1,481 1,549 1,646 1,840 1,961 2,603 2,415
Total Current Liabilities
149 134 244 280 273 599 241 312 448 309
Short-Term Debt
- - - 14 0.00 309 - 0.00 44 0.00
Accounts Payable
28 21 25 29 16 17 12 18 26 43
Accrued Expenses
28 36 67 48 67 90 89 140 148 108
Current Deferred Revenue
67 51 125 160 118 108 98 91 151 79
Current Deferred & Payable Income Tax Liabilities
- - - 0.86 33 1.32 0.04 6.25 2.15 0.03
Current Employee Benefit Liabilities
16 24 25 29 37 66 39 49 68 70
Other Current Liabilities
9.03 1.19 1.62 - 2.03 7.30 3.53 7.54 8.83 9.28
Total Noncurrent Liabilities
598 679 714 1,200 1,276 1,048 1,599 1,649 2,155 2,106
Long-Term Debt
389 501 593 628 770 600 1,221 1,183 1,230 1,245
Capital Lease Obligations
- - - - - - 19 179 171 162
Noncurrent Deferred Revenue
134 91 108 567 490 424 352 288 241 157
Other Noncurrent Operating Liabilities
75 87 13 4.91 16 23 6.95 0.00 514 542
Total Equity & Noncontrolling Interests
201 100 365 1,187 1,685 743 772 573 387 588
Total Preferred & Common Equity
201 100 281 1,048 1,471 743 772 573 387 588
Total Common Equity
201 100 281 1,048 1,471 743 772 573 387 588
Common Stock
1,309 1,311 1,554 2,047 2,204 1,896 1,964 2,060 2,215 2,869
Retained Earnings
-1,095 -1,181 -1,241 -967 -708 -1,131 -1,160 -1,430 -1,796 -2,250
Accumulated Other Comprehensive Income / (Loss)
-14 -30 -32 -32 -25 -21 -33 -57 -33 -31

Quarterly Balance Sheets for Ionis Pharmaceuticals

This table presents Ionis Pharmaceuticals' assets and liabilities at the end of each period, using quarterly balance sheet data. All values are USD millions unless otherwise specified.

Metric Q3 2022 Q1 2023 Q2 2023 Q3 2023 Q1 2024 Q2 2024 Q3 2024
Total Assets
2,422 2,885 2,971 2,934 2,764 2,691 3,081
Total Current Assets
2,152 2,543 2,617 2,585 2,416 2,329 2,714
Cash & Equivalents
315 309 425 352 349 294 335
Short-Term Investments
1,667 2,038 1,961 1,884 1,857 1,785 2,149
Inventories, net
21 22 26 26 30 29 28
Other Current Assets
150 174 206 323 179 222 202
Plant, Property, & Equipment, net
181 85 92 71 73 76 83
Total Noncurrent Assets
89 257 263 278 275 286 285
Other Noncurrent Operating Assets
59 257 263 278 275 286 285
Total Liabilities & Shareholders' Equity
2,422 2,885 2,971 2,934 2,764 2,691 3,081
Total Liabilities
1,828 2,399 2,543 2,619 2,467 2,427 2,419
Total Current Liabilities
283 259 288 404 328 306 305
Short-Term Debt
- - - - 44 44 44
Accounts Payable
21 10 24 5.62 13 9.24 9.05
Accrued Expenses
128 113 105 119 106 114 124
Current Deferred Revenue
100 92 96 205 130 94 76
Current Deferred & Payable Income Tax Liabilities
0.02 17 25 31 2.21 0.28 0.04
Current Employee Benefit Liabilities
30 18 29 34 22 35 41
Other Current Liabilities
4.97 8.24 8.90 9.95 9.99 8.80 10
Total Noncurrent Liabilities
1,544 2,139 2,255 2,214 2,140 2,121 2,114
Long-Term Debt
1,224 1,177 1,299 1,230 1,189 1,191 1,192
Capital Lease Obligations
- 177 175 173 169 166 168
Noncurrent Deferred Revenue
295 273 254 249 215 189 174
Other Noncurrent Operating Liabilities
25 513 527 562 567 576 580
Total Equity & Noncontrolling Interests
594 487 428 315 297 264 662
Total Preferred & Common Equity
594 487 428 315 297 264 662
Total Common Equity
594 487 428 315 297 264 662
Common Stock
2,035 2,090 2,118 2,148 2,270 2,304 2,832
Retained Earnings
-1,377 -1,554 -1,639 -1,787 -1,939 -2,005 -2,145
Accumulated Other Comprehensive Income / (Loss)
-63 -49 -51 -46 -35 -35 -24

Annual Metrics and Ratios for Ionis Pharmaceuticals

This table displays calculated financial ratios and metrics derived from Ionis Pharmaceuticals' official financial filings.

Metric 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024
Growth Metrics
- - - - - - - - - -
Revenue Growth
32.47% 31.40% 37.93% 16.63% 87.20% -35.04% 11.13% -27.53% 34.10% -10.48%
EBITDA Growth
-89.90% 198.76% 158.62% -120.91% 2,633.64% -137.22% 101.67% -10,023.08% -45.79% -42.53%
EBIT Growth
-58.73% 73.39% 198.26% -410.72% 693.30% -147.14% 76.80% -570.56% -26.80% -39.88%
NOPAT Growth
-58.73% 73.39% 254.00% -297.67% 822.18% -138.83% 82.46% -1,258.88% 13.76% -34.31%
Net Income Growth
-126.45% 31.58% 82.15% 2,093.74% 33.62% -267.01% 94.04% -843.18% -35.80% -23.92%
EPS Growth
-124.24% 32.43% 130.00% 1,280.00% -8.21% -267.37% 93.71% -850.00% -34.74% -18.75%
Operating Cash Flow Growth
236.12% -630.67% 255.34% 246.20% -42.67% -89.62% -14.19% -990.84% -12.08% -62.90%
Free Cash Flow Firm Growth
-136.10% -877.58% 112.99% 598.20% -32.12% -25.47% -312.46% -112.73% 159.23% -365.34%
Invested Capital Growth
-20.50% 69.53% 0.91% -295.19% 82.34% -433.22% 57.26% 49.03% -855.25% 39.57%
Revenue Q/Q Growth
-10.50% 56.73% -3.51% 4.23% 36.73% -21.81% 22.66% -32.91% 28.07% -12.19%
EBITDA Q/Q Growth
-165.52% 126.94% -51.17% 53.04% 136.21% -225.23% 100.97% -572.07% 11.58% -28.46%
EBIT Q/Q Growth
-2,663.02% 86.60% -78.77% 21.56% 215.79% -255.42% 85.87% -2,637.52% 13.37% -28.71%
NOPAT Q/Q Growth
-2,663.02% 86.60% -77.52% 21.67% -20.66% -286.89% 88.96% -2,495.45% 36.34% -28.27%
Net Income Q/Q Growth
-721.33% 67.15% -121.39% 321.83% -28.55% -850.78% 95.30% -3,784.22% 10.54% -26.50%
EPS Q/Q Growth
-716.67% 67.11% -67.39% 1,085.71% -40.44% -776.60% 95.38% -3,266.67% 10.80% -24.59%
Operating Cash Flow Q/Q Growth
-83.66% 8.66% 37.22% 18.73% 88.56% -83.36% 141.11% -311.85% 43.11% -42.34%
Free Cash Flow Firm Q/Q Growth
-132.33% -135.70% 187.27% -64.55% 326.45% 197.97% -367.71% -101,558.85% 666.96% -47.33%
Invested Capital Q/Q Growth
-88.71% 56.43% -125.35% 48.96% 30.23% -415.54% 41.19% 67.88% 3.25% 27.38%
Profitability Metrics
- - - - - - - - - -
Gross Margin
100.00% 100.00% 100.00% 99.70% 99.61% 98.36% 98.66% 97.60% 98.84% 98.41%
EBITDA Margin
-9.81% 7.38% 13.83% -2.48% 33.55% -19.23% 0.29% -39.67% -43.13% -68.66%
Operating Margin
-26.70% -5.41% 6.04% -10.23% 32.59% -23.60% -3.72% -69.84% -44.91% -67.37%
EBIT Margin
-26.70% -5.41% 3.85% -10.26% 32.53% -23.61% -4.93% -45.60% -43.12% -67.38%
Profit (Net Income) Margin
-31.12% -16.20% -2.10% 35.85% 25.59% -65.78% -3.53% -45.92% -46.50% -64.37%
Tax Burden Percent
100.42% 105.11% 64.33% -282.30% 84.80% 356.55% 98.11% 104.55% 109.68% 98.66%
Interest Burden Percent
116.03% 285.05% -84.62% 123.72% 92.76% 78.16% 72.97% 96.31% 98.33% 96.84%
Effective Tax Rate
0.00% 0.00% 0.00% 0.00% 15.20% 0.00% 0.00% 0.00% 0.00% 0.00%
Return on Invested Capital (ROIC)
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
ROIC Less NNEP Spread (ROIC-NNEP)
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Return on Net Nonoperating Assets (RNNOA)
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Return on Equity (ROE)
-38.50% -40.22% -4.64% 27.70% 20.01% -39.52% -3.78% -40.12% -76.34% -93.10%
Cash Return on Invested Capital (CROIC)
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Operating Return on Assets (OROA)
-7.96% -2.17% 1.77% -3.09% 12.38% -6.12% -1.60% -10.41% -12.30% -15.85%
Return on Assets (ROA)
-9.27% -6.49% -0.96% 10.77% 9.74% -17.06% -1.14% -10.48% -13.26% -15.15%
Return on Common Equity (ROCE)
-38.50% -40.22% -3.80% 23.71% 17.55% -36.05% -3.78% -40.12% -76.34% -93.10%
Return on Equity Simple (ROE_SIMPLE)
-43.97% -60.66% -3.84% 20.51% 19.53% -64.54% -3.71% -47.08% -94.72% -77.15%
Net Operating Profit after Tax (NOPAT)
-53 -14 22 -43 310 -120 -21 -287 -248 -333
NOPAT Margin
-18.69% -3.79% 4.23% -7.16% 27.64% -16.52% -2.61% -48.88% -31.44% -47.16%
Net Nonoperating Expense Percent (NNEP)
-8.29% -15.98% -10.94% 27.56% -1.45% -26.49% -0.80% 2.32% -15.70% -13.66%
Return On Investment Capital (ROIC_SIMPLE)
- - - - - - - -14.84% -13.52% -16.66%
Cost of Revenue to Revenue
0.00% 0.00% 0.00% 0.30% 0.39% 1.64% 1.34% 2.40% 1.16% 1.59%
SG&A Expenses to Revenue
13.10% 13.04% 21.10% 40.79% 25.53% 48.59% 22.99% 25.59% 29.53% 37.93%
R&D to Revenue
113.60% 92.37% 72.86% 69.14% 41.48% 73.37% 79.39% 141.84% 114.22% 127.85%
Operating Expenses to Revenue
126.70% 105.41% 93.96% 109.93% 67.02% 121.96% 102.39% 167.43% 143.75% 165.78%
Earnings before Interest and Taxes (EBIT)
-76 -20 20 -62 365 -172 -40 -268 -340 -475
Earnings before Interest, Taxes, Depreciation and Amortization (EBITDA)
-28 27 71 -15 377 -140 2.35 -233 -340 -484
Valuation Ratios
- - - - - - - - - -
Price to Book Value (P/BV)
37.05 58.22 22.34 7.10 5.78 10.64 5.57 9.37 18.77 9.38
Price to Tangible Book Value (P/TBV)
40.99 73.20 24.24 7.26 5.88 11.05 5.57 9.37 18.77 9.38
Price to Revenue (P/Rev)
26.22 15.55 12.21 12.40 7.57 10.84 5.30 9.13 9.22 7.83
Price to Earnings (P/E)
0.00 0.00 18,142.24 27.17 30.55 0.00 0.00 0.00 0.00 0.00
Dividend Yield
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Earnings Yield
0.00% 0.00% 0.01% 3.68% 3.27% 0.00% 0.00% 0.00% 0.00% 0.00%
Enterprise Value to Invested Capital (EV/IC)
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Enterprise Value to Revenue (EV/Rev)
24.76 15.11 11.54 10.23 6.22 9.49 4.22 8.07 8.09 6.57
Enterprise Value to EBITDA (EV/EBITDA)
0.00 204.86 83.42 0.00 18.54 0.00 1,457.68 0.00 0.00 0.00
Enterprise Value to EBIT (EV/EBIT)
0.00 0.00 299.43 0.00 19.12 0.00 0.00 0.00 0.00 0.00
Enterprise Value to NOPAT (EV/NOPAT)
0.00 0.00 272.93 0.00 22.50 0.00 0.00 0.00 0.00 0.00
Enterprise Value to Operating Cash Flow (EV/OCF)
332.51 0.00 34.06 10.17 20.20 192.86 111.13 0.00 0.00 0.00
Enterprise Value to Free Cash Flow (EV/FCFF)
0.00 0.00 280.60 41.56 69.68 92.71 0.00 0.00 31.88 0.00
Leverage & Solvency
- - - - - - - - - -
Debt to Equity
1.94 5.03 1.62 0.54 0.46 1.22 1.61 2.38 3.74 2.39
Long-Term Debt to Equity
1.94 5.03 1.62 0.53 0.46 0.81 1.61 2.38 3.62 2.39
Financial Leverage
-1.85 -1.93 -1.28 -1.21 -1.10 -1.12 -1.23 -1.12 -1.58 -1.82
Leverage Ratio
4.15 6.19 4.81 2.57 2.05 2.32 3.30 3.83 5.76 6.15
Compound Leverage Factor
4.82 17.66 -4.07 3.18 1.91 1.81 2.41 3.69 5.66 5.95
Debt to Total Capital
65.98% 83.41% 61.88% 35.09% 31.37% 55.01% 61.65% 70.39% 78.89% 70.52%
Short-Term Debt to Total Capital
0.00% 0.00% 0.00% 0.75% 0.00% 18.69% 0.00% 0.00% 2.42% 0.00%
Long-Term Debt to Total Capital
65.98% 83.41% 61.88% 34.34% 31.37% 36.32% 61.65% 70.39% 76.47% 70.52%
Preferred Equity to Total Capital
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Noncontrolling Interests to Total Capital
0.00% 0.00% 8.79% 7.60% 8.70% 0.00% 0.00% 0.00% 0.00% 0.00%
Common Equity to Total Capital
34.02% 16.59% 29.33% 57.30% 59.93% 44.99% 38.35% 29.61% 21.11% 29.48%
Debt to EBITDA
-13.99 18.20 8.34 -43.17 2.04 -6.48 528.36 -5.84 -4.25 -2.91
Net Debt to EBITDA
14.89 -5.99 -6.05 97.02 -4.59 7.01 -372.40 2.68 2.61 1.84
Long-Term Debt to EBITDA
-13.99 18.20 8.34 -42.25 2.04 -4.28 528.36 -5.84 -4.12 -2.91
Debt to NOPAT
-7.34 -35.47 27.28 -14.94 2.48 -7.55 -58.71 -4.74 -5.83 -4.23
Net Debt to NOPAT
7.82 11.67 -19.78 33.57 -5.57 8.16 41.38 2.18 3.58 2.68
Long-Term Debt to NOPAT
-7.34 -35.47 27.28 -14.62 2.48 -4.98 -58.71 -4.74 -5.66 -4.23
Altman Z-Score
5.26 3.68 3.90 3.52 4.61 3.05 2.01 1.63 1.60 0.96
Noncontrolling Interest Sharing Ratio
0.00% 0.00% 18.13% 14.39% 12.28% 8.79% 0.00% 0.00% 0.00% 0.00%
Liquidity Ratios
- - - - - - - - - -
Current Ratio
5.62 5.96 4.80 7.88 9.97 3.56 9.75 7.07 5.90 8.47
Quick Ratio
5.48 5.78 4.20 7.44 9.16 3.16 8.79 6.38 5.20 7.43
Cash Flow Metrics
- - - - - - - - - -
Free Cash Flow to Firm (FCFF)
-17 -163 21 148 100 75 -159 -337 200 -530
Operating Cash Flow to CapEx
179.82% -972.46% 460.02% 3,415.51% 1,118.35% 102.20% 257.62% 0.00% -1,293.00% -1,106.33%
Free Cash Flow to Firm to Interest Expense
-0.45 -3.81 0.47 3.30 1.27 7.85 -16.97 -41.55 2.45 -5.86
Operating Cash Flow to Interest Expense
0.58 -2.62 3.89 13.46 4.40 3.77 3.29 -33.78 -3.78 -5.54
Operating Cash Flow Less CapEx to Interest Expense
0.26 -2.89 3.05 13.07 4.00 0.08 2.02 -4.43 -4.07 -6.04
Efficiency Ratios
- - - - - - - - - -
Asset Turnover
0.30 0.40 0.46 0.30 0.38 0.26 0.32 0.23 0.29 0.24
Accounts Receivable Turnover
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Inventory Turnover
0.00 0.00 0.00 0.20 0.33 0.60 0.46 0.60 0.62 1.12
Fixed Asset Turnover
3.17 4.07 4.79 4.72 7.86 4.36 4.51 4.65 10.84 8.53
Accounts Payable Turnover
0.00 0.00 0.00 0.07 0.20 0.72 0.75 0.95 0.42 0.33
Days Sales Outstanding (DSO)
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Days Inventory Outstanding (DIO)
0.00 0.00 0.00 1,861.50 1,114.07 613.25 787.28 605.56 588.96 324.69
Days Payable Outstanding (DPO)
0.00 0.00 0.00 5,369.31 1,861.92 508.16 489.88 385.60 878.19 1,122.68
Cash Conversion Cycle (CCC)
0.00 0.00 0.00 -3,507.81 -747.86 105.08 297.40 219.97 -289.23 -797.99
Capital & Investment Metrics
- - - - - - - - - -
Invested Capital
-214 -65 -65 -255 -45 -240 -103 -52 -500 -302
Invested Capital Turnover
-1.45 -2.67 -7.93 -3.75 -7.48 -5.11 -4.73 -7.58 -2.85 -1.76
Increase / (Decrease) in Invested Capital
-36 149 0.59 -191 210 -195 138 50 -447 198
Enterprise Value (EV)
7,024 5,632 5,932 6,134 6,981 6,922 3,423 4,740 6,372 4,630
Market Capitalization
7,439 5,797 6,277 7,437 8,497 7,906 4,297 5,365 7,258 5,520
Book Value per Share
$1.67 $0.82 $2.25 $7.62 $10.46 $5.32 $5.47 $4.03 $2.70 $3.73
Tangible Book Value per Share
$1.51 $0.65 $2.08 $7.44 $10.28 $5.12 $5.47 $4.03 $2.70 $3.73
Total Capital
590 600 958 1,829 2,455 1,652 2,012 1,935 1,831 1,996
Total Debt
389 501 593 642 770 909 1,241 1,362 1,445 1,407
Total Long-Term Debt
389 501 593 628 770 600 1,241 1,362 1,400 1,407
Net Debt
-415 -165 -430 -1,442 -1,730 -983 -874 -625 -886 -890
Capital Expenditures (CapEx)
12 12 38 18 31 35 12 -238 24 45
Debt-free, Cash-free Net Working Capital (DFCFNWC)
-116 -1.08 -98 -143 -52 -52 -10 -96 -93 13
Debt-free Net Working Capital (DFNWC)
688 664 925 1,941 2,448 1,841 2,104 1,891 2,238 2,311
Net Working Capital (NWC)
688 664 925 1,928 2,448 1,532 2,104 1,891 2,194 2,311
Net Nonoperating Expense (NNE)
35 46 33 -258 23 359 7.47 -17 119 121
Net Nonoperating Obligations (NNO)
-415 -165 -430 -1,442 -1,730 -983 -874 -625 -886 -890
Total Depreciation and Amortization (D&A)
48 48 51 47 11 32 42 35 -0.06 -9.05
Debt-free, Cash-free Net Working Capital to Revenue
-40.83% -0.29% -18.98% -23.80% -4.63% -7.10% -1.29% -16.30% -11.82% 1.89%
Debt-free Net Working Capital to Revenue
242.55% 178.16% 179.92% 323.73% 218.03% 252.39% 259.67% 321.97% 284.15% 327.73%
Net Working Capital to Revenue
242.55% 178.16% 179.92% 321.44% 218.03% 210.05% 259.67% 321.97% 278.52% 327.73%
Earnings Adjustments
- - - - - - - - - -
Adjusted Basic Earnings per Share
($0.74) ($0.72) $0.08 $2.09 $2.12 ($3.23) ($0.20) ($1.90) ($2.56) ($3.04)
Adjusted Weighted Average Basic Shares Outstanding
120.66M 123.75M 124.02M 132.32M 140.00M 139.61M 141.02M 141.85M 143.19M 149.51M
Adjusted Diluted Earnings per Share
($0.74) ($0.72) $0.08 $2.07 $2.08 ($3.23) ($0.20) ($1.90) ($2.56) ($3.04)
Adjusted Weighted Average Diluted Shares Outstanding
120.66M 123.75M 126.10M 134.06M 142.87M 139.61M 141.02M 141.85M 143.19M 149.51M
Adjusted Basic & Diluted Earnings per Share
($0.74) ($0.72) $0.08 $0.00 $2.12 $0.00 $0.00 $0.00 $0.00 $0.00
Adjusted Weighted Average Basic & Diluted Shares Outstanding
119.72M 120.93M 125.40M 138.40M 139.22M 140.86M 141.69M 142.95M 145.75M 158.96M
Normalized Net Operating Profit after Tax (NOPAT)
-53 -14 22 -43 310 -120 -21 -287 -248 -333
Normalized NOPAT Margin
-18.69% -3.79% 4.23% -7.16% 27.64% -16.52% -2.61% -48.88% -31.44% -47.16%
Pre Tax Income Margin
-30.99% -15.42% -3.26% -12.70% 30.18% -18.45% -3.60% -43.92% -42.40% -65.25%
Debt Service Ratios
- - - - - - - - - -
EBIT to Interest Expense
-2.06 -0.47 0.44 -1.37 4.64 -18.10 -4.27 -32.98 -4.17 -5.25
NOPAT to Interest Expense
-1.44 -0.33 0.49 -0.96 3.95 -12.67 -2.26 -35.35 -3.04 -3.68
EBIT Less CapEx to Interest Expense
-2.38 -0.74 -0.40 -1.77 4.25 -21.79 -5.55 -3.63 -4.46 -5.75
NOPAT Less CapEx to Interest Expense
-1.76 -0.60 -0.36 -1.35 3.55 -16.36 -3.54 -6.00 -3.33 -4.18
Payout Ratios
- - - - - - - - - -
Dividend Payout Ratio
0.00% 0.00% 0.00% 0.00% 0.00% -113.54% 0.00% 0.00% 0.00% 0.00%
Augmented Payout Ratio
0.00% -1.35% -18.89% 0.00% 11.97% -132.41% 0.00% 0.00% 0.00% 0.00%

Quarterly Metrics and Ratios for Ionis Pharmaceuticals

This table displays calculated financial ratios and metrics derived from Ionis Pharmaceuticals' official financial filings.

Metric Q3 2022 Q4 2022 Q1 2023 Q2 2023 Q3 2023 Q4 2023 Q1 2024 Q2 2024 Q3 2024 Q4 2024
Growth Metrics
- - - - - - - - - -
Revenue Growth
20.04% -65.48% -8.03% 40.82% -9.74% 113.64% -8.45% 19.55% -7.21% -30.18%
EBITDA Growth
38.04% -122.37% -138.50% 9.59% -202.27% 86.24% -35.14% 14.08% -6.39% -1,510.86%
EBIT Growth
36.93% -126.48% -98.75% 19.22% -158.66% 89.90% -31.00% 17.13% -5.47% -1,800.15%
NOPAT Growth
31.10% -166.09% -98.50% -5.47% -142.19% 97.06% -30.98% 26.72% -3.76% -1,710.21%
Net Income Growth
43.02% -123.34% -90.78% 18.88% -213.69% 82.33% -14.86% 22.31% 4.70% -1,026.51%
EPS Growth
43.10% -123.27% -89.13% 18.92% -212.12% 83.78% -12.64% 25.00% 7.77% -1,000.00%
Operating Cash Flow Growth
56.04% -198.29% -323.36% -438.04% -346.28% 116.42% -11.90% -23.13% -5.47% -453.38%
Free Cash Flow Firm Growth
-127.84% -336.64% 304.84% 399.85% 577.56% 326.18% -133.83% -147.09% -180.81% -162.13%
Invested Capital Growth
6.68% 49.03% -319.84% -178.05% -217.11% -855.25% -0.24% 14.43% 19.49% 39.57%
Revenue Q/Q Growth
19.42% -4.93% -14.07% 44.35% -23.46% 125.03% -63.18% 88.50% -40.59% 69.32%
EBITDA Q/Q Growth
46.64% -10.29% -116.76% 29.13% -78.40% 94.98% -2,029.23% 54.94% -120.92% 24.00%
EBIT Q/Q Growth
44.34% -7.07% -95.43% 30.64% -78.22% 95.82% -2,435.01% 56.12% -126.80% 24.68%
NOPAT Q/Q Growth
30.83% -251.66% 45.13% 20.98% -58.84% 95.73% -2,342.22% 55.80% -124.93% 25.45%
Net Income Q/Q Growth
55.30% -11.57% -137.12% 31.40% -72.83% 93.72% -1,441.65% 53.60% -112.00% 25.72%
EPS Q/Q Growth
55.41% -12.12% -135.14% 31.03% -71.67% 94.17% -1,533.33% 54.08% -111.11% 30.53%
Operating Cash Flow Q/Q Growth
-35.00% -719.50% 33.07% 27.34% -11.97% 130.15% -556.22% 20.05% 4.08% -1.00%
Free Cash Flow Firm Q/Q Growth
35.40% -269.29% 256.07% -19.46% 2.88% 74.90% -121.33% -12.10% -76.55% -34.48%
Invested Capital Q/Q Growth
6.26% 67.88% -867.70% 4.56% -6.90% 3.25% 6.30% 18.52% -0.57% 27.38%
Profitability Metrics
- - - - - - - - - -
Gross Margin
99.05% 97.57% 98.97% 98.65% 98.48% 99.06% 98.20% 98.15% 99.20% 98.31%
EBITDA Margin
-29.29% -33.98% -85.71% -42.08% -98.08% -2.19% -126.51% -30.24% -112.46% -50.48%
Operating Margin
-37.03% -136.95% -87.45% -47.87% -99.35% -1.89% -125.12% -29.34% -111.09% -48.91%
EBIT Margin
-34.08% -38.38% -87.28% -41.94% -97.65% -1.81% -124.89% -29.07% -110.99% -49.37%
Profit (Net Income) Margin
-29.41% -34.52% -95.25% -45.27% -102.22% -2.85% -119.50% -29.42% -104.98% -46.05%
Tax Burden Percent
100.61% 118.27% 110.08% 110.13% 104.69% 334.89% 100.05% 100.10% 97.49% 97.49%
Interest Burden Percent
85.80% 76.05% 99.14% 98.02% 99.99% 46.98% 95.64% 101.10% 97.03% 95.69%
Effective Tax Rate
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Return on Invested Capital (ROIC)
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
ROIC Less NNEP Spread (ROIC-NNEP)
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Return on Net Nonoperating Assets (RNNOA)
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Return on Equity (ROE)
1.30% -40.12% -54.99% -58.69% -90.01% -76.34% -98.27% -105.71% -73.38% -93.10%
Cash Return on Invested Capital (CROIC)
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Operating Return on Assets (OROA)
-12.34% -8.76% -18.60% -9.75% -22.43% -0.52% -34.34% -8.35% -29.64% -11.62%
Return on Assets (ROA)
-10.65% -7.88% -20.30% -10.52% -23.48% -0.81% -32.86% -8.45% -28.03% -10.84%
Return on Common Equity (ROCE)
1.30% -40.12% -54.99% -58.69% -90.01% -76.34% -98.27% -105.71% -73.38% -93.10%
Return on Equity Simple (ROE_SIMPLE)
1.23% 0.00% -67.59% -72.15% -129.80% 0.00% -129.76% -138.70% -54.16% 0.00%
Net Operating Profit after Tax (NOPAT)
-41 -146 -80 -63 -100 -4.29 -105 -46 -104 -78
NOPAT Margin
-25.92% -95.87% -61.22% -33.51% -69.54% -1.32% -87.58% -20.54% -77.76% -34.24%
Net Nonoperating Expense Percent (NNEP)
-0.76% 12.43% -4.87% -2.59% -5.93% -0.66% -4.25% -2.52% -3.81% -3.01%
Return On Investment Capital (ROIC_SIMPLE)
- -7.53% - - - -0.23% - - - -3.89%
Cost of Revenue to Revenue
0.95% 2.43% 1.03% 1.35% 1.52% 0.94% 1.80% 1.85% 0.80% 1.69%
SG&A Expenses to Revenue
21.54% 31.57% 34.87% 24.49% 48.51% 21.88% 44.05% 28.91% 46.06% 38.87%
R&D to Revenue
114.54% 202.96% 151.55% 122.03% 149.32% 79.06% 179.26% 98.59% 164.23% 108.35%
Operating Expenses to Revenue
136.08% 234.53% 186.42% 146.52% 197.83% 100.94% 223.32% 127.49% 210.29% 147.22%
Earnings before Interest and Taxes (EBIT)
-54 -58 -114 -79 -141 -5.89 -149 -65 -149 -112
Earnings before Interest, Taxes, Depreciation and Amortization (EBITDA)
-47 -52 -112 -79 -141 -7.10 -151 -68 -150 -114
Valuation Ratios
- - - - - - - - - -
Price to Book Value (P/BV)
10.56 9.37 10.50 13.71 20.61 18.77 20.98 26.38 8.84 9.38
Price to Tangible Book Value (P/TBV)
11.12 9.37 10.50 13.71 20.61 18.77 20.98 26.38 8.84 9.38
Price to Revenue (P/Rev)
7.17 9.13 8.87 9.31 10.57 9.22 8.01 8.55 7.29 7.83
Price to Earnings (P/E)
857.54 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Dividend Yield
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Earnings Yield
0.12% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Enterprise Value to Invested Capital (EV/IC)
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Enterprise Value to Revenue (EV/Rev)
6.31 8.07 7.15 7.86 9.22 8.09 6.97 7.72 5.95 6.57
Enterprise Value to EBITDA (EV/EBITDA)
111.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Enterprise Value to EBIT (EV/EBIT)
523.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Enterprise Value to NOPAT (EV/NOPAT)
460.58 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Enterprise Value to Operating Cash Flow (EV/OCF)
42.63 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Enterprise Value to Free Cash Flow (EV/FCFF)
16,598.04 0.00 69.84 0.00 0.00 31.88 0.00 0.00 0.00 0.00
Leverage & Solvency
- - - - - - - - - -
Debt to Equity
2.06 2.38 2.78 3.44 4.45 3.74 4.73 5.31 2.12 2.39
Long-Term Debt to Equity
2.06 2.38 2.78 3.44 4.45 3.62 4.58 5.15 2.05 2.39
Financial Leverage
-1.30 -1.12 -1.52 -1.62 -1.75 -1.58 -2.29 -2.30 -1.95 -1.82
Leverage Ratio
4.30 3.83 4.52 5.15 5.89 5.76 7.21 8.18 6.15 6.15
Compound Leverage Factor
3.69 2.91 4.48 5.05 5.89 2.70 6.90 8.27 5.97 5.88
Debt to Total Capital
67.32% 70.39% 73.56% 77.48% 81.65% 78.89% 82.54% 84.16% 67.96% 70.52%
Short-Term Debt to Total Capital
0.00% 0.00% 0.00% 0.00% 0.00% 2.42% 2.61% 2.67% 2.15% 0.00%
Long-Term Debt to Total Capital
67.32% 70.39% 73.56% 77.48% 81.65% 76.47% 79.93% 81.50% 65.81% 70.52%
Preferred Equity to Total Capital
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Noncontrolling Interests to Total Capital
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Common Equity to Total Capital
32.68% 29.61% 26.44% 22.52% 18.35% 21.11% 17.46% 15.84% 32.04% 29.48%
Debt to EBITDA
24.81 -5.84 -4.54 -5.09 -3.65 -4.25 -3.70 -3.81 -3.73 -2.91
Net Debt to EBITDA
-15.34 2.68 3.33 3.15 2.17 2.61 2.12 1.84 2.86 1.84
Long-Term Debt to EBITDA
24.81 -5.84 -4.54 -5.09 -3.65 -4.12 -3.58 -3.69 -3.61 -2.91
Debt to NOPAT
102.15 -4.74 -4.14 -4.47 -3.61 -5.83 -5.15 -5.49 -5.42 -4.23
Net Debt to NOPAT
-63.18 2.18 3.04 2.76 2.14 3.58 2.95 2.65 4.16 2.68
Long-Term Debt to NOPAT
102.15 -4.74 -4.14 -4.47 -3.61 -5.66 -4.99 -5.31 -5.25 -4.23
Altman Z-Score
2.48 1.90 1.54 1.68 1.58 1.97 1.54 1.80 1.52 1.36
Noncontrolling Interest Sharing Ratio
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Liquidity Ratios
- - - - - - - - - -
Current Ratio
7.59 7.07 9.81 9.09 6.39 5.90 7.37 7.61 8.91 8.47
Quick Ratio
6.99 6.38 9.05 8.28 5.53 5.20 6.73 6.79 8.15 7.43
Cash Flow Metrics
- - - - - - - - - -
Free Cash Flow to Firm (FCFF)
-53 -196 306 246 253 443 -103 -116 -205 -275
Operating Cash Flow to CapEx
-440.80% -4,836.80% -1,279.53% -810.62% -5,092.11% 0.00% -3,337.15% -1,923.00% -1,269.77% -455.50%
Free Cash Flow to Firm to Interest Expense
-24.81 -113.20 17.86 12.35 11.53 19.78 -4.68 -5.09 -9.02 -12.05
Operating Cash Flow to Interest Expense
-11.42 -115.65 -7.83 -4.88 -4.96 1.47 -6.78 -5.26 -5.07 -5.08
Operating Cash Flow Less CapEx to Interest Expense
-14.01 -118.04 -8.44 -5.48 -5.06 1.50 -6.98 -5.53 -5.47 -6.20
Efficiency Ratios
- - - - - - - - - -
Asset Turnover
0.36 0.23 0.21 0.23 0.23 0.29 0.28 0.29 0.27 0.24
Accounts Receivable Turnover
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Inventory Turnover
0.58 0.60 0.49 0.40 0.42 0.62 0.38 0.43 0.39 1.12
Fixed Asset Turnover
4.85 4.65 4.38 4.69 4.89 10.84 9.83 9.71 10.47 8.53
Accounts Payable Turnover
0.88 0.95 0.85 0.53 0.75 0.42 0.84 0.70 1.42 0.33
Days Sales Outstanding (DSO)
0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00
Days Inventory Outstanding (DIO)
628.30 605.56 747.39 911.37 865.63 588.96 963.06 856.04 944.74 324.69
Days Payable Outstanding (DPO)
416.74 385.60 430.41 690.77 489.31 878.19 432.91 524.78 256.20 1,122.68
Cash Conversion Cycle (CCC)
211.57 219.97 316.99 220.60 376.32 -289.23 530.15 331.25 688.55 -797.99
Capital & Investment Metrics
- - - - - - - - - -
Invested Capital
-163 -52 -506 -483 -517 -500 -508 -414 -416 -302
Invested Capital Turnover
-5.19 -7.58 -1.84 -1.92 -1.81 -2.85 -1.53 -1.81 -1.72 -1.76
Increase / (Decrease) in Invested Capital
12 50 -386 -309 -354 -447 -1.20 70 101 198
Enterprise Value (EV)
5,521 4,740 4,116 4,960 5,669 6,372 5,415 6,279 4,779 4,630
Market Capitalization
6,278 5,365 5,109 5,871 6,501 7,258 6,220 6,957 5,857 5,520
Book Value per Share
$4.19 $4.03 $3.40 $2.99 $2.20 $2.70 $2.04 $1.81 $4.53 $3.73
Tangible Book Value per Share
$3.98 $4.03 $3.40 $2.99 $2.20 $2.70 $2.04 $1.81 $4.53 $3.73
Total Capital
1,819 1,935 1,840 1,902 1,719 1,831 1,699 1,665 2,067 1,996
Total Debt
1,224 1,362 1,354 1,474 1,404 1,445 1,402 1,401 1,405 1,407
Total Long-Term Debt
1,224 1,362 1,354 1,474 1,404 1,400 1,358 1,357 1,360 1,407
Net Debt
-757 -625 -993 -912 -832 -886 -804 -677 -1,078 -890
Capital Expenditures (CapEx)
5.54 4.14 10 12 2.14 -0.82 4.49 6.23 9.06 25
Debt-free, Cash-free Net Working Capital (DFCFNWC)
-113 -96 -63 -57 -55 -93 -74 -11 -30 13
Debt-free Net Working Capital (DFNWC)
1,869 1,891 2,283 2,329 2,180 2,238 2,132 2,068 2,454 2,311
Net Working Capital (NWC)
1,869 1,891 2,283 2,329 2,180 2,194 2,088 2,023 2,409 2,311
Net Nonoperating Expense (NNE)
5.58 -93 44 22 47 4.98 38 20 36 27
Net Nonoperating Obligations (NNO)
-757 -625 -993 -912 -832 -886 -804 -677 -1,078 -890
Total Depreciation and Amortization (D&A)
7.65 6.68 2.05 -0.27 -0.62 -1.21 -1.94 -2.64 -1.97 -2.51
Debt-free, Cash-free Net Working Capital to Revenue
-12.91% -16.30% -11.00% -8.98% -8.97% -11.82% -9.50% -1.36% -3.68% 1.89%
Debt-free Net Working Capital to Revenue
213.44% 321.97% 396.44% 369.30% 354.52% 284.15% 274.58% 254.18% 305.55% 327.73%
Net Working Capital to Revenue
213.44% 321.97% 396.44% 369.30% 354.52% 278.52% 268.86% 248.72% 300.01% 327.73%
Earnings Adjustments
- - - - - - - - - -
Adjusted Basic Earnings per Share
($0.33) ($0.37) ($0.87) ($0.60) ($1.03) ($0.06) ($0.98) ($0.45) ($0.95) ($0.66)
Adjusted Weighted Average Basic Shares Outstanding
141.95M 141.85M 142.74M 143.10M 143.32M 143.19M 145.54M 145.96M 148.59M 149.51M
Adjusted Diluted Earnings per Share
($0.33) ($0.37) ($0.87) ($0.60) ($1.03) ($0.06) ($0.98) ($0.45) ($0.95) ($0.66)
Adjusted Weighted Average Diluted Shares Outstanding
141.95M 141.85M 142.74M 143.10M 143.32M 143.19M 145.54M 145.96M 148.59M 149.51M
Adjusted Basic & Diluted Earnings per Share
$0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00 $0.00
Adjusted Weighted Average Basic & Diluted Shares Outstanding
142.05M 142.95M 143.09M 143.33M 143.47M 145.75M 145.97M 146.21M 157.90M 158.96M
Normalized Net Operating Profit after Tax (NOPAT)
-41 -146 -80 -63 -100 -4.29 -105 -46 -104 -78
Normalized NOPAT Margin
-25.92% -95.87% -61.22% -33.51% -69.54% -1.32% -87.58% -20.54% -77.76% -34.24%
Pre Tax Income Margin
-29.24% -29.19% -86.53% -41.11% -97.64% -0.85% -119.44% -29.39% -107.69% -47.24%
Debt Service Ratios
- - - - - - - - - -
EBIT to Interest Expense
-25.45 -33.68 -6.65 -3.96 -6.41 -0.26 -6.75 -2.87 -6.54 -4.89
NOPAT to Interest Expense
-19.36 -84.12 -4.67 -3.17 -4.56 -0.19 -4.73 -2.03 -4.59 -3.39
EBIT Less CapEx to Interest Expense
-28.04 -36.07 -7.26 -4.56 -6.50 -0.23 -6.95 -3.15 -6.94 -6.01
NOPAT Less CapEx to Interest Expense
-21.95 -86.51 -5.28 -3.77 -4.66 -0.15 -4.94 -2.30 -4.98 -4.51
Payout Ratios
- - - - - - - - - -
Dividend Payout Ratio
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Augmented Payout Ratio
0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%

Frequently Asked Questions About Ionis Pharmaceuticals' Financials

When does Ionis Pharmaceuticals's financial year end?

According to the most recent income statement we have on file, Ionis Pharmaceuticals' fiscal year ends in December. Their fiscal year 2024 ended on December 31, 2024.

How has Ionis Pharmaceuticals' net income changed over the last 9 years?

Ionis Pharmaceuticals' net income appears to be on an upward trend, with a most recent value of -$453.90 million in 2024, rising from -$88.28 million in 2015. The previous period was -$366.29 million in 2023.

What is Ionis Pharmaceuticals's operating income?
Ionis Pharmaceuticals's total operating income in 2024 was -$475.08 million, based on the following breakdown:
  • Total Gross Profit: $693.92 million
  • Total Operating Expenses: $1.17 billion
How has Ionis Pharmaceuticals revenue changed over the last 9 years?

Over the last 9 years, Ionis Pharmaceuticals' total revenue changed from $283.70 million in 2015 to $705.14 million in 2024, a change of 148.5%.

How much debt does Ionis Pharmaceuticals have?

Ionis Pharmaceuticals' total liabilities were at $2.42 billion at the end of 2024, a 7.2% decrease from 2023, and a 223.3% increase since 2015.

How much cash does Ionis Pharmaceuticals have?

In the past 9 years, Ionis Pharmaceuticals' cash and equivalents has ranged from $84.69 million in 2016 to $869.19 million in 2021, and is currently $242.08 million as of their latest financial filing in 2024.

How has Ionis Pharmaceuticals' book value per share changed over the last 9 years?

Over the last 9 years, Ionis Pharmaceuticals' book value per share changed from 1.67 in 2015 to 3.73 in 2024, a change of 122.9%.



This page (NASDAQ:IONS) was last updated on 4/25/2025 by MarketBeat.com Staff
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