Ionis Pharmaceuticals (IONS) Short Interest Ratio & Short Volume $32.33 -0.36 (-1.11%) Closing price 02/21/2025 03:59 PM EasternExtended Trading$32.40 +0.07 (+0.23%) As of 02/21/2025 06:56 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrends Ionis Pharmaceuticals Short Interest DataIonis Pharmaceuticals (IONS) has a short interest of 12.12 million shares, representing 7.87% of the float (the number of shares available for trading by the public). This marks a 18.36% increase in short interest from the previous month. The short interest ratio (days to cover) is 7.9, indicating that it would take 7.9 days of the average trading volume of 1.69 million shares to cover all short positions.Current Short Interest12,120,000 sharesPrevious Short Interest10,240,000 sharesChange Vs. Previous Month+18.36%Dollar Volume Sold Short$386.63 millionShort Interest Ratio7.9 Days to CoverLast Record DateJanuary 31, 2025Outstanding Shares157,900,000 sharesFloat Size153,910,000 sharesShort Percent of Float7.87%Today's Trading Volume1,569,929 sharesAverage Trading Volume1,689,898 sharesToday's Volume Vs. Average93% Short Selling Ionis Pharmaceuticals? Sign up to receive the latest short interest report for Ionis Pharmaceuticals and its competitors with MarketBeat's FREE newsletter. Email Address Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartIONS Short Interest Over TimeIONS Days to Cover Over TimeIONS Percentage of Float Shorted Over Time Ionis Pharmaceuticals Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 1/31/202512,120,000 shares $386.63 million +18.4%7.9%7.9 $31.90 1/15/202510,240,000 shares $340.07 million -6.1%7.0%7.1 $33.21 12/31/202410,900,000 shares $381.06 million +3.5%7.5%7.8 $34.96 12/15/202410,530,000 shares $385.50 million +0.8%7.2%7.1 $36.61 11/30/202410,450,000 shares $373.38 million -5.4%7.2%6.1 $35.73 11/15/202411,050,000 shares $379.46 million +2.9%7.6%6.5 $34.34 10/31/202410,740,000 shares $412.31 million +8.8%7.4%7 $38.39 10/15/20249,870,000 shares $373.48 million -6.3%6.8%6.3 $37.84 9/30/202410,530,000 shares $421.83 million -0.8%7.2%6.6 $40.06 9/15/202410,610,000 shares $447.64 million +4.4%7.3%6.4 $42.19 Get the Latest News and Ratings for IONS and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Ionis Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. 8/31/202410,160,000 shares $484.43 million +2.6%7.6%6.8 $47.68 8/15/20249,900,000 shares $461.98 million +4.7%7.4%8 $46.67 7/31/20249,460,000 shares $467.89 million +1.0%7.0%7 $49.46 7/15/20249,370,000 shares $445.73 million -1.6%7.0%7.2 $47.57 6/30/20249,520,000 shares $453.72 million +10.1%7.1%7.8 $47.66 6/15/20248,650,000 shares $351.62 million +0.6%6.5%7.5 $40.65 5/31/20248,600,000 shares $323.10 million -0.4%6.4%8.3 $37.57 5/15/20248,630,000 shares $338.38 million -1.4%6.4%7.9 $39.21 4/30/20248,750,000 shares $361.03 million -8.2%6.5%8.1 $41.26 4/15/20249,530,000 shares $395.97 million +0.1%7.1%8.9 $41.55 3/31/20249,520,000 shares $412.69 million -1.6%7.1%8.2 $43.35 3/15/20249,670,000 shares $411.46 million +6.2%7.2%8.1 $42.55 2/29/20249,110,000 shares $411.86 million +0.6%6.8%7.4 $45.21 2/15/20249,060,000 shares $410.24 million +7.2%6.8%7.4 $45.28 1/31/20248,450,000 shares $434.25 million -1.1%6.0%7.5 $51.39 1/15/20248,540,000 shares $457.23 million +3.6%6.1%7.4 $53.54 12/31/20238,240,000 shares $416.86 million -3.7%5.9%7.5 $50.59 12/15/20238,560,000 shares $425.43 million -11.8%6.1%7.3 $49.70 11/30/20239,700,000 shares $479.86 million -0.4%6.9%8.7 $49.47 11/15/20239,740,000 shares $484.76 million +0.4%7.0%9.4 $49.77 10/31/20239,700,000 shares $429.42 million +6.2%6.9%9.6 $44.27 10/15/20239,130,000 shares $438.06 million -1.8%6.5%9 $47.98 9/30/20239,300,000 shares $421.85 million -0.9%6.6%9.2 $45.36 9/15/20239,380,000 shares $402.50 million +1.0%6.7%10.1 $42.91 8/31/20239,290,000 shares $374.11 million -3.7%6.6%9.7 $40.27 8/15/20239,650,000 shares $386 million +4.8%6.9%7.9 $40.00 7/31/20239,210,000 shares $381.57 million +4.0%6.6%7.3 $41.43 7/15/20238,860,000 shares $376.37 million +2.8%6.4%7 $42.48 6/30/20238,620,000 shares $353.68 million -0.8%6.2%7.2 $41.03 6/15/20238,690,000 shares $362.29 million +33.3%6.2%7.2 $41.69Trump doesn’t give a damn (Ad)Porter Stansberry: “I met with Trump’s biggest backers… they’re scooping up these 10 stocks” I recently met with one of Trump’s longest-serving advisors. We helped put together a plan to help investors capitalize on Trump’s election. And we found out these 10 stocks are the most likely to boom…Go here now to find out the names of these 10 stocks. 5/31/20236,520,000 shares $266.67 million -8.3%4.7%5.5 $40.90 5/15/20237,110,000 shares $257.67 million No Change5.1%7.3 $36.24 10/31/20226,860,000 shares $303.21 million -2.0%4.9%6.9 $44.20 10/15/20227,000,000 shares $324.52 million -3.5%5.0%6.9 $46.36 9/30/20227,250,000 shares $320.67 million +6.6%5.2%7.4 $44.23 9/15/20226,800,000 shares $322.93 million +9.2%4.9%7.1 $47.49 8/31/20226,230,000 shares $264.90 million -7.7%4.5%6.8 $42.52 8/15/20226,750,000 shares $299.77 million +10.7%4.8%7.2 $44.41 7/31/20226,100,000 shares $229.12 million +0.5%4.4%6 $37.56 7/15/20226,070,000 shares $238.61 million +5.9%4.3%6.1 $39.31 6/30/20225,730,000 shares $212.12 million +1.4%4.1%5.3 $37.02 6/15/20225,650,000 shares $195.89 million -5.7%4.5%5.1 $34.67 5/31/20225,990,000 shares $218.75 million -16.1%4.3%5.5 $36.52 5/15/20227,140,000 shares $257.61 million +9.2%5.1%6.6 $36.08 4/30/20226,540,000 shares $240.41 million -12.2%4.7%6.1 $36.76 4/15/20227,450,000 shares $305.23 million +3.9%5.3%6.5 $40.97 3/31/20227,170,000 shares $265.58 million -1.7%N/A0 $37.04 3/15/20227,290,000 shares $238.38 million -4.1%5.2%6.6 $32.70 2/28/20227,600,000 shares $253.69 million -18.7%5.4%6.2 $33.38 2/15/20229,350,000 shares $314.72 million -1.8%6.7%7.2 $33.66 1/31/20229,520,000 shares $302.74 million +31.9%6.8%7.7 $31.80 1/15/20227,220,000 shares $238.84 million -1.5%N/A0 $33.08 12/31/20217,330,000 shares $223.05 million -0.8%5.3%6.4 $30.43 12/15/20217,390,000 shares $229.90 million +8.2%5.3%6.6 $31.11 11/30/20216,830,000 shares $181.00 million +10.3%4.9%6.4 $26.50 11/15/20216,190,000 shares $202.97 million -10.4%4.4%6.4 $32.79 10/29/20216,910,000 shares $220.22 million +1.9%5.0%7.5 $31.87 10/15/20216,780,000 shares $237.98 million +2.1%4.9%7.4 $35.10 9/30/20216,640,000 shares $222.71 million -7.4%4.8%7.7 $33.54 9/15/20217,170,000 shares $265.00 million -6.8%5.1%7.3 $36.96 8/31/20217,690,000 shares $305.75 million -8.5%5.5%7.7 $39.76 8/13/20218,400,000 shares $333.31 million -8.6%6.0%6.4 $39.68 7/30/20219,190,000 shares $341.32 million +7.2%6.6%6.1 $37.14 7/15/20218,570,000 shares $305.69 million -4.8%6.4%5.1 $35.67 6/30/20219,000,000 shares $359.01 million +0.3%6.7%5.3 $39.89 6/15/20218,970,000 shares $329.02 million -17.3%6.7%4.9 $36.68 5/28/202110,850,000 shares $404.16 million +1.0%8.1%5.7 $37.25 5/14/202110,740,000 shares $401.35 million +4.2%8.0%6.6 $37.37 4/30/202110,310,000 shares $446.63 million +6.7%7.7%7.1 $43.32 4/15/20219,660,000 shares $404.08 million +10.2%N/A7.5 $41.83 3/31/20218,770,000 shares $392.11 million +2.2%6.5%7.1 $44.71 3/15/20218,580,000 shares $454.65 million +0.9%6.4%7.3 $52.99 2/26/20218,500,000 shares $453.99 million +7.1%6.3%7.9 $53.41 2/12/20217,940,000 shares $460.12 million +5.2%6.0%7.4 $57.95 1/29/20217,550,000 shares $458.21 million +2.6%5.7%6.9 $60.69 1/15/20217,360,000 shares $451.54 million -5.4%5.5%6.8 $61.35 12/31/20207,780,000 shares $445.02 million +7.8%5.9%6.8 $57.20 12/15/20207,220,000 shares $345.33 million +2.1%5.4%6.1 $47.83 11/30/20207,070,000 shares $361.49 million +4.1%5.3%6.7 $51.13 11/15/20206,790,000 shares $350.16 million -5.7%5.1%6.9 $51.57Trump doesn’t give a damn (Ad)Porter Stansberry: “I met with Trump’s biggest backers… they’re scooping up these 10 stocks” I recently met with one of Trump’s longest-serving advisors. We helped put together a plan to help investors capitalize on Trump’s election. And we found out these 10 stocks are the most likely to boom…Go here now to find out the names of these 10 stocks. 10/30/20207,200,000 shares $337.32 million -11.8%5.4%7.6 $46.85 10/15/20208,160,000 shares $389.31 million +0.1%6.2%8.9 $47.71 9/30/20208,150,000 shares $386.72 million +3.0%6.1%9.8 $47.45 9/15/20207,910,000 shares $418.68 million +4.1%6.0%10.2 $52.93 8/31/20207,600,000 shares $414.20 million -0.7%5.7%10.4 $54.50 8/14/20207,650,000 shares $403.77 million -6.0%5.8%10 $52.78 7/31/20208,140,000 shares $468.54 million -4.6%6.1%10.3 $57.56 7/15/20208,530,000 shares $524.60 million -1.2%6.4%10.6 $61.50 6/30/20208,630,000 shares $508.82 million -5.8%6.5%10.4 $58.96 6/15/20209,160,000 shares $524.04 million +4.0%6.9%10.6 $57.21 5/29/20208,810,000 shares $495.21 million +4.6%6.7%9.4 $56.21 5/15/20208,420,000 shares $446.85 million +4.5%6.4%8.3 $53.07 4/30/20208,060,000 shares $447.57 million -4.6%6.1%8.2 $55.53 4/15/20208,450,000 shares $429.34 million +0.5%6.4%8.6 $50.81 3/31/20208,410,000 shares $489.04 million -4.5%6.4%8.2 $58.15 3/13/20208,810,400 shares $466.95 million +0.1%6.7%7.3 $53.00 2/28/20208,800,000 shares $366.08 million +0.5%6.7%9.1 $41.60 IONS Short Interest - Frequently Asked Questions What is Ionis Pharmaceuticals' current short interest? Short interest is the volume of Ionis Pharmaceuticals shares that have been sold short but have not yet been covered or closed out. As of January 31st, traders have sold 12,120,000 shares of IONS short. 7.87% of Ionis Pharmaceuticals' shares are currently sold short. Learn More on Ionis Pharmaceuticals' current short interest. What is a good short interest ratio for Ionis Pharmaceuticals? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. IONS shares currently have a short interest ratio of 8.0. Learn More on Ionis Pharmaceuticals's short interest ratio. Which institutional investors are shorting Ionis Pharmaceuticals? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of Ionis Pharmaceuticals: CSS LLC IL, Wolverine Trading LLC, Torno Capital LLC, Royal Bank of Canada, Group One Trading LLC, Deutsche Bank AG, Citadel Advisors LLC, Jane Street Group LLC, Tudor Investment Corp ET AL, Two Sigma Securities LLC, Susquehanna International Group LLP, Concourse Financial Group Securities Inc., Walleye Trading LLC, Walleye Capital LLC, Barclays PLC, JPMorgan Chase & Co., Twin Tree Management LP, and Wolverine Asset Management LLC. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. What is a good short interest percentage for Ionis Pharmaceuticals? Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 7.87% of Ionis Pharmaceuticals' floating shares are currently sold short. Is Ionis Pharmaceuticals' short interest increasing or decreasing? Ionis Pharmaceuticals saw a increase in short interest in the month of January. As of January 31st, there was short interest totaling 12,120,000 shares, an increase of 18.4% from the previous total of 10,240,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. What is Ionis Pharmaceuticals' float size? Ionis Pharmaceuticals currently has issued a total of 157,900,000 shares. Some of Ionis Pharmaceuticals' outstanding shares are available for trading, while others are subject to various restrictions. The public float, also referred to as floating shares or "the float", are shares that publicly owned, unrestricted and available to trade on the open market. Ionis Pharmaceuticals currently has a public float of 153,910,000 shares. How does Ionis Pharmaceuticals' short interest compare to its competitors? 7.87% of Ionis Pharmaceuticals' shares are currently sold short. Here is how the short interest of companies in the industry of "biotechnology" compare to Ionis Pharmaceuticals: United Therapeutics Co. (4.59%), Incyte Co. (3.06%), BioMarin Pharmaceutical Inc. (2.36%), Neurocrine Biosciences, Inc. (2.41%), Exelixis, Inc. (4.72%), Exact Sciences Co. (5.37%), Repligen Co. (6.38%), Halozyme Therapeutics, Inc. (7.22%), Madrigal Pharmaceuticals, Inc. (18.25%), Alkermes plc (6.83%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: AppLovin Co. ($5.21 billion), Charter Communications, Inc. ($4.07 billion), Reddit, Inc. ($3.33 billion), The Kroger Co. ($2.67 billion), Cencora, Inc. ($2.29 billion), Hims & Hers Health, Inc. ($2.17 billion), SoFi Technologies, Inc. ($1.99 billion), Live Nation Entertainment, Inc. ($1.87 billion), Rivian Automotive, Inc. ($1.76 billion), and Moderna, Inc. ($1.60 billion). View all of the most shorted stocks. What does it mean to sell short Ionis Pharmaceuticals stock? Short selling IONS is an investing strategy that aims to generate trading profit from Ionis Pharmaceuticals as its price is falling. IONS shares are trading down $0.36 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Ionis Pharmaceuticals? A short squeeze for Ionis Pharmaceuticals occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of IONS, which in turn drives the price of the stock up even further. How often is Ionis Pharmaceuticals' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including IONS, twice per month. The most recent reporting period available is January, 31 2025. More Short Interest Resources from MarketBeat Related Companies UTHR Short Interest INCY Short Interest BMRN Short Interest NBIX Short Interest EXEL Short Interest EXAS Short Interest RGEN Short Interest HALO Short Interest MDGL Short Interest ALKS Short Interest Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:IONS) was last updated on 2/22/2025 by MarketBeat.com Staff From Our Partners[RFK Jr CONFIRMED] Here’s why Dems are TERRIFIEDRobert F. Kennedy Jr was just confirmed as Trump’s secretary of Health and Human Services… but it was NOT easy...NewMarket Health Publishing, LLC. | SponsoredSecret financial plot unfolding in Washington DC… [DEVELOPING]What stocks are next up to soar in 2025? I believe I’ve found the answer - and it might surprise you. 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