| 8/15/2025 | Shay Capital LLC | 210,516 | $2.10M | 0.2% | N/A | 0.476% | |
| 8/15/2025 | Silver Point Capital L.P. | 290,000 | $2.89M | 0.2% | N/A | 0.656% | |
| 8/15/2025 | Rangeley Capital LLC | 302,080 | $3.01M | 3.7% | N/A | 0.683% | |
| 8/15/2025 | Oxford Asset Management LLP | 41,771 | $416K | 0.2% | +110.0% | 0.094% | |
| 8/15/2025 | Man Group plc | 58,768 | $586K | 0.0% | +160.8% | 0.133% | |
| 8/15/2025 | LMR Partners LLP | 550,000 | $5.48M | 0.0% | N/A | 1.244% | |
| 8/15/2025 | EcoR1 Capital LLC | 10,688,978 | $106.57M | 6.3% | N/A | 24.178% | |
| 8/15/2025 | Engineers Gate Manager LP | 59,559 | $594K | 0.0% | +61.8% | 0.135% | |
| 8/15/2025 | Bluefin Capital Management LLC | 30,530 | $304K | 0.2% | N/A | 0.069% | |
| 8/15/2025 | Bank of America Corp DE | 308,660 | $3.08M | 0.0% | +71.4% | 0.698% | |
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| 8/15/2025 | Ameriprise Financial Inc. | 207,787 | $2.07M | 0.0% | +5.0% | 0.470% | |
| 8/14/2025 | Sandia Investment Management LP | 24,865 | $248K | 0.6% | N/A | 0.056% | |
| 8/14/2025 | Nantahala Capital Management LLC | 596,666 | $5.95M | 0.2% | N/A | 1.350% | |
| 8/14/2025 | Orbimed Advisors LLC | 700,000 | $6.98M | 0.2% | N/A | 1.583% | |
| 8/14/2025 | Caption Management LLC | 22,157 | $221K | 0.0% | -106.1% | 0.050% | |
| 8/14/2025 | Nebula Research & Development LLC | 28,909 | $288K | 0.0% | N/A | 0.065% | |
| 8/14/2025 | Diadema Partners LP | 206,200 | $2.06M | 0.6% | N/A | 0.466% | |
| 8/13/2025 | Gabelli Funds LLC | 120,593 | $1.20M | 0.0% | N/A | 0.273% | |
| 8/13/2025 | GABELLI & Co INVESTMENT ADVISERS INC. | 146,450 | $1.46M | 0.2% | N/A | 0.331% | |
| 8/13/2025 | Marshall Wace LLP | 611,649 | $6.10M | 0.0% | +411.6% | 1.384% | |
| 8/13/2025 | Stonepine Capital Management LLC | 310,033 | $3.09M | 3.0% | +181.8% | 0.701% | |
| 8/13/2025 | Invesco Ltd. | 81,035 | $808K | 0.0% | -4.9% | 0.183% | |
| 8/13/2025 | Virtus Investment Advisers LLC | 9,422 | $94K | 0.0% | -54.4% | 0.021% | |
| 8/13/2025 | Hsbc Holdings PLC | 68,533 | $686K | 0.0% | -11.0% | 0.155% | |
| 8/13/2025 | DLD Asset Management LP | 576,655 | $5.75M | 0.0% | N/A | 1.304% | |
| 8/12/2025 | XTX Topco Ltd | 34,777 | $347K | 0.0% | N/A | 0.079% | |
| 8/12/2025 | Prudential Financial Inc. | 42,861 | $427K | 0.0% | -39.4% | 0.097% | |
| 8/12/2025 | American Century Companies Inc. | 78,949 | $787K | 0.0% | +5.9% | 0.179% | |
| 8/12/2025 | Rhumbline Advisers | 48,882 | $487K | 0.0% | +12.4% | 0.111% | |
| 8/12/2025 | JPMorgan Chase & Co. | 601,363 | $6.00M | 0.0% | -69.7% | 1.360% | |
| 8/12/2025 | Dynamic Technology Lab Private Ltd | 77,371 | $771K | 0.1% | +587.3% | 0.175% | |
| 8/11/2025 | Persistent Asset Partners Ltd | 47,512 | $474K | 0.4% | N/A | 0.107% | |
| 8/8/2025 | Intech Investment Management LLC | 20,806 | $207K | 0.0% | +13.4% | 0.054% | |
| 8/8/2025 | Bailard Inc. | 15,200 | $152K | 0.0% | N/A | 0.040% | |
| 8/8/2025 | Geode Capital Management LLC | 703,467 | $7.02M | 0.0% | +8.2% | 1.838% | |
| 8/7/2025 | Campbell & CO Investment Adviser LLC | 72,262 | $720K | 0.0% | N/A | 0.189% | |
| 8/1/2025 | Y Intercept Hong Kong Ltd | 28,375 | $283K | 0.0% | +56.6% | 0.074% | |
| 7/31/2025 | Peapod Lane Capital LLC | 169,287 | $1.69M | 1.7% | +24.8% | 0.442% | |
| 7/31/2025 | AlphaQuest LLC | 29,019 | $289K | 0.0% | -5.6% | 0.076% | |
| 7/30/2025 | FNY Investment Advisers LLC | 65,000 | $648K | 0.3% | N/A | 0.170% | |
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| 7/25/2025 | CWM LLC | 12,013 | $120K | 0.0% | +40.4% | 0.031% | |
| 7/23/2025 | KLP Kapitalforvaltning AS | 55,400 | $552K | 0.0% | +42.4% | 0.145% | |
| 7/23/2025 | Regency Capital Management Inc. DE | 58,000 | $578K | 0.3% | N/A | 0.152% | |
| 6/27/2025 | Goldman Sachs Group Inc. | 587,420 | $3.51M | 0.0% | -19.6% | 1.535% | |
| 5/28/2025 | Strs Ohio | 5,200 | $31K | 0.0% | N/A | 0.014% | |
| 5/21/2025 | Acadian Asset Management LLC | 536,787 | $3.20M | 0.0% | +14.2% | 1.402% | |
| 5/19/2025 | Jane Street Group LLC | 21,438 | $128K | 0.0% | -117.1% | 0.056% | |
| 5/16/2025 | Goldman Sachs Group Inc. | 587,420 | $3.51M | 0.0% | -19.6% | 1.535% | |
| 5/16/2025 | Dynamic Technology Lab Private Ltd | 11,257 | $67K | 0.0% | N/A | 0.029% | |
| 5/16/2025 | Jacobs Levy Equity Management Inc. | 557,936 | $3.33M | 0.0% | -39.5% | 1.458% | |
| 5/16/2025 | BVF Inc. IL | 3,075,000 | $18.36M | 0.7% | +32.3% | 8.034% | |
| 5/16/2025 | AQR Capital Management LLC | 226,210 | $1.35M | 0.0% | +88.6% | 0.591% | |
| 5/16/2025 | 683 Capital Management LLC | 1,750,000 | $10.45M | 0.7% | +90.6% | 4.572% | |
| 5/16/2025 | ADAR1 Capital Management LLC | 101,096 | $604K | 0.1% | -23.2% | 0.264% | |
| 5/15/2025 | RA Capital Management L.P. | 3,649,057 | $21.79M | 0.4% | +74.4% | 9.534% | |
| 5/15/2025 | Paloma Partners Management Co | 10,947 | $65K | 0.0% | N/A | 0.029% | |
| 5/15/2025 | Cubist Systematic Strategies LLC | 112,092 | $669K | 0.0% | +80.3% | 0.293% | |
| 5/15/2025 | DAFNA Capital Management LLC | 213,347 | $1.27M | 0.4% | +13.3% | 0.557% | |
| 5/15/2025 | Trexquant Investment LP | 188,500 | $1.13M | 0.0% | +4.7% | 0.493% | |
| 5/14/2025 | Ieq Capital LLC | 14,749 | $88K | 0.0% | N/A | 0.039% | |
| 5/14/2025 | AlphaQuest LLC | 30,747 | $184K | 0.0% | -25.6% | 0.080% | |
| 5/14/2025 | Hsbc Holdings PLC | 76,993 | $458K | 0.0% | +62.4% | 0.201% | |
| 5/14/2025 | Wellington Management Group LLP | 140,119 | $837K | 0.0% | +27.0% | 0.366% | |
| 5/13/2025 | Algert Global LLC | 79,952 | $477K | 0.0% | +15.0% | 0.209% | |
| 5/13/2025 | American Century Companies Inc. | 74,532 | $445K | 0.0% | +9.7% | 0.195% | |
| 5/13/2025 | Russell Investments Group Ltd. | 45,184 | $270K | 0.0% | -21.0% | 0.118% | |
| 5/12/2025 | Nuveen LLC | 303,650 | $1.81M | 0.0% | N/A | 0.793% | |
| 5/9/2025 | Deutsche Bank AG | 33,586 | $201K | 0.0% | +168.0% | 0.088% | |
| 5/9/2025 | Charles Schwab Investment Management Inc. | 233,561 | $1.39M | 0.0% | +17.3% | 0.610% | |
| 5/6/2025 | Readystate Asset Management LP | 17,040 | $102K | 0.0% | -60.5% | 0.045% | |
| 5/1/2025 | CWM LLC | 8,554 | $51K | 0.0% | +428.7% | 0.022% | |
| 4/30/2025 | Peapod Lane Capital LLC | 135,655 | $810K | 0.9% | +24.6% | 0.355% | |
| 4/29/2025 | Bank of New York Mellon Corp | 64,806 | $387K | 0.0% | -3.6% | 0.170% | |
| 4/17/2025 | Exchange Traded Concepts LLC | 17,308 | $103K | 0.0% | +25.1% | 0.045% | |
| 3/24/2025 | Wellington Management Group LLP | 110,332 | $847K | 0.0% | +4.3% | 0.289% | |
| 2/19/2025 | Public Employees Retirement System of Ohio | 84,220 | $647K | 0.0% | +192.2% | 0.231% | |
| 2/17/2025 | Vestal Point Capital LP | 900,000 | $6.91M | 0.4% | -12.2% | 2.464% | |
| 2/17/2025 | Squarepoint Ops LLC | 42,716 | $328K | 0.0% | -30.4% | 0.117% | |
| 2/17/2025 | Stonepine Capital Management LLC | 110,000 | $845K | 0.7% | +266.7% | 0.301% | |
| 2/17/2025 | Tang Capital Management LLC | 221,716 | $1.70M | 0.1% | -90.8% | 0.607% | |
| 2/17/2025 | Point72 Asia Singapore Pte. Ltd. | 5,427 | $42K | 0.0% | N/A | 0.015% | |
| 2/17/2025 | Man Group plc | 29,169 | $224K | 0.0% | +34.7% | 0.080% | |
| 2/17/2025 | Nuveen Asset Management LLC | 60,401 | $464K | 0.0% | -61.6% | 0.165% | |
| 2/17/2025 | OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC | 125,589 | $965K | 0.1% | +90.5% | 0.344% | |
| 2/17/2025 | Millennium Management LLC | 411,072 | $3.16M | 0.0% | +1,008.8% | 1.125% | |
| 2/17/2025 | Jacobs Levy Equity Management Inc. | 922,134 | $7.08M | 0.0% | +347.9% | 2.524% | |
| 2/17/2025 | Graham Capital Management L.P. | 11,126 | $85K | 0.0% | N/A | 0.030% | |
| 2/17/2025 | Forefront Analytics LLC | 11,061 | $85K | 0.0% | N/A | 0.030% | |
| 2/17/2025 | Deutsche Bank AG | 12,531 | $96K | 0.0% | -53.5% | 0.034% | |
| 2/17/2025 | D. E. Shaw & Co. Inc. | 56,534 | $434K | 0.0% | -55.0% | 0.155% | |
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| 2/17/2025 | DAFNA Capital Management LLC | 188,347 | $1.45M | 0.4% | +16.6% | 0.516% | |
| 2/17/2025 | Cubist Systematic Strategies LLC | 62,178 | $478K | 0.0% | -53.0% | 0.170% | |
| 2/17/2025 | Bridgeway Capital Management LLC | 69,072 | $530K | 0.0% | +5.0% | 0.189% | |
| 2/17/2025 | BVF Inc. IL | 2,325,000 | $17.86M | 0.6% | N/A | 6.365% | |
| 2/17/2025 | Balyasny Asset Management L.P. | 28,350 | $218K | 0.0% | N/A | 0.078% | |
| 2/17/2025 | Bank of America Corp DE | 61,331 | $471K | 0.0% | -20.1% | 0.168% | |
| 2/17/2025 | BNP Paribas Financial Markets | 60,079 | $461K | 0.0% | N/A | 0.164% | |
| 2/17/2025 | Ameriprise Financial Inc. | 205,188 | $1.58M | 0.0% | +233.6% | 0.562% | |
| 2/17/2025 | Algert Global LLC | 69,512 | $534K | 0.0% | -72.9% | 0.190% | |
| 2/17/2025 | Almitas Capital LLC | 275,120 | $2.11M | 0.5% | N/A | 0.753% | |
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