Lexicon Pharmaceuticals (LXRX) Short Interest Ratio & Short Volume $0.95 +0.12 (+15.20%) As of 06/30/2025 04:00 PM Eastern Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Lexicon Pharmaceuticals Short Interest DataLexicon Pharmaceuticals (LXRX) has a short interest of 37.56 million shares, representing 12.07% of the float (the number of shares available for trading by the public). This marks a -3.27% decrease in short interest from the previous month. The short interest ratio (days to cover) is 2.8, indicating that it would take 2.8 days of the average trading volume of 6.82 million shares to cover all short positions.Current Short Interest37,560,000 sharesPrevious Short Interest38,830,000 sharesChange Vs. Previous Month-3.27%Dollar Volume Sold Short$25.22 millionShort Interest Ratio2.8 Days to CoverLast Record DateJune 15, 2025Outstanding Shares361,490,000 sharesShort Percent of Float12.07%Today's Trading Volume8,889,000 sharesAverage Trading Volume6,823,508 sharesToday's Volume Vs. Average130% Short Selling Lexicon Pharmaceuticals? Sign up to receive the latest short interest report for Lexicon Pharmaceuticals and its competitors with MarketBeat's FREE newsletter. Email Address Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartLXRX Short Interest Over TimeLXRX Days to Cover Over TimeLXRX Percentage of Float Shorted Over Time Lexicon Pharmaceuticals Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 6/15/202537,560,000 shares $25.22 million -3.3%12.1%2.8 $0.67 5/31/202538,830,000 shares $24.94 million -9.8%16.9%2.9 $0.64 5/15/202543,030,000 shares $22.81 million +15.5%18.8%2.9 $0.53 4/30/202537,270,000 shares $27.24 million -9.8%N/A2.5 $0.73 4/15/202541,330,000 shares $21.17 million -5.8%18.0%2.8 $0.51 3/31/202543,880,000 shares $20.22 million +11.8%19.1%3 $0.46 3/15/202539,260,000 shares $14.39 million -17.3%17.1%6.3 $0.37 2/28/202547,460,000 shares $33.51 million +6.1%20.7%7.3 $0.71 2/15/202544,740,000 shares $35.12 million +4.0%19.5%9.3 $0.78 1/31/202543,030,000 shares $32.54 million +10.1%N/A9 $0.76 Get the Latest News and Ratings for LXRX and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Lexicon Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. 1/15/202539,100,000 shares $28.45 million +16.7%N/A8 $0.73 12/31/202433,500,000 shares $24.74 million +7.1%N/A7.8 $0.74 12/15/202431,280,000 shares $25.35 million -0.8%N/A7.6 $0.81 11/30/202431,530,000 shares $25.22 million +0.5%N/A9.6 $0.80 11/15/202431,380,000 shares $30.60 million +9.5%N/A9.7 $0.98 10/31/202428,650,000 shares $55.87 million +3.6%N/A9.5 $1.95 10/15/202427,650,000 shares $49.49 million +2.5%N/A10.1 $1.79 9/30/202426,970,000 shares $42.34 million +1.3%N/A9.4 $1.57 9/15/202426,630,000 shares $45.27 million +4.9%N/A9.5 $1.70 8/31/202425,390,000 shares $43.92 million +3.5%N/A8.8 $1.73 8/15/202424,530,000 shares $40.23 million +9.8%N/A8.5 $1.64 7/31/202422,350,000 shares $50.29 million +7.0%N/A8 $2.25 7/15/202420,880,000 shares $44.27 million +3.4%N/A7.6 $2.12 6/30/202420,200,000 shares $33.94 million -6.4%N/A7.8 $1.68 6/15/202421,570,000 shares $39.26 million -14.2%N/A7.7 $1.82 5/31/202425,140,000 shares $42.74 million +8.0%N/A7.3 $1.70 5/15/202423,270,000 shares $45.14 million -0.7%N/A6.3 $1.94 4/30/202423,440,000 shares $36.10 million +16.5%N/A5.3 $1.54 4/15/202420,120,000 shares $37.62 million -8.2%N/A4.2 $1.87 3/31/202421,910,000 shares $52.58 million +2.6%N/A4.7 $2.40 3/15/202421,350,000 shares $55.51 million +1.3%N/A4.6 $2.60 2/29/202421,070,000 shares $52.46 million -10.0%N/A4.9 $2.49 2/15/202423,410,000 shares $83.81 million +1.7%N/A6.4 $3.58 1/31/202423,030,000 shares $43.07 million -8.9%N/A8 $1.87 1/15/202425,270,000 shares $34.62 million +8.8%N/A10.3 $1.37 12/31/202323,220,000 shares $35.53 million -0.3%N/A8.6 $1.53 12/15/202323,280,000 shares $29.57 million -0.5%N/A9.1 $1.27 11/30/202323,400,000 shares $24.80 million +4.6%N/A9.3 $1.06 11/15/202322,370,000 shares $25.50 million +1.8%N/A9.3 $1.14 10/31/202321,980,000 shares $27.26 million +12.7%N/A9.9 $1.24Banks aren’t ready for this altcoin—are you? 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Only one project is perfectly positioned to fill it…Discover our #1 crypto for the market right now. 10/15/202319,500,000 shares $23.21 million -3.7%N/A9.1 $1.19 9/30/202320,240,000 shares $22.06 million +7.1%N/A11.2 $1.09 9/15/202318,900,000 shares $26.46 million +6.1%N/A11.5 $1.40 8/31/202317,810,000 shares $30.63 million +1.5%N/A9.5 $1.72 8/15/202317,550,000 shares $28.61 million -2.2%N/A6.6 $1.63 7/31/202317,950,000 shares $36.08 million +14.2%N/A6.9 $2.01 7/15/202315,720,000 shares $34.74 million +8.7%N/A6.3 $2.21 6/30/202314,460,000 shares $33.11 million +38.0%N/A6.1 $2.29 6/15/202310,480,000 shares $26.93 million -2.6%N/A4.9 $2.57 5/31/202310,760,000 shares $35.51 million +66.8%N/A6.3 $3.30 5/15/20236,450,000 shares $19.22 million +30.8%N/A8.5 $2.98 4/30/20234,930,000 shares $11.78 million +17.4%N/A8.1 $2.39 4/15/20234,200,000 shares $10.12 million +3.5%N/A9.5 $2.41 3/31/20234,060,000 shares $9.87 million +2.3%N/A10.3 $2.43 3/15/20233,970,000 shares $9.09 million +4.2%N/A9.3 $2.29 2/28/20233,810,000 shares $8.57 million -8.0%N/A9.3 $2.25 2/15/20234,140,000 shares $9.44 million +3.5%N/A11.3 $2.28 1/31/20234,000,000 shares $8.96 million +2.6%N/A10.6 $2.24 1/15/20233,900,000 shares $9.20 million +0.3%N/A9.8 $2.36 12/30/20223,890,000 shares $7.43 million +2.9%N/A9.3 $1.91 12/15/20223,780,000 shares $8.05 million +0.3%N/A8.6 $2.13 11/30/20223,770,000 shares $8.07 million -2.3%N/A7.8 $2.14 11/15/20223,860,000 shares $8.96 million -9.4%N/A7.5 $2.32 10/31/20224,260,000 shares $9.16 million -4.7%N/A6.4 $2.15 10/15/20224,470,000 shares $9.43 million -0.2%N/A4.4 $2.11 9/30/20224,480,000 shares $10.75 million +11.4%N/A4.3 $2.40 9/15/20224,020,000 shares $10.77 million +7.8%N/A2.4 $2.68 8/31/20223,730,000 shares $10.26 million +1.9%N/A2.2 $2.75 8/15/20223,660,000 shares $12.55 million -55.2%N/A2.2 $3.43 7/31/20228,170,000 shares $19.44 million -0.9%N/A5.3 $2.38 7/15/20228,240,000 shares $25.38 million +6.6%8.0%6.9 $3.08 6/30/20227,730,000 shares $14.38 million +34.4%7.5%6.6 $1.86 6/15/20225,750,000 shares $8.05 million +5.7%5.6%10.5 $1.40 5/31/20225,440,000 shares $9.63 million +1.3%N/A10.9 $1.77 5/15/20225,370,000 shares $9.29 million +0.9%N/A8.8 $1.73 4/30/20225,320,000 shares $9.63 million +11.5%N/A8.4 $1.81 4/15/20224,770,000 shares $11.11 million +2.8%N/A7.3 $2.33 3/31/20224,640,000 shares $9.70 million -2.1%N/A7.1 $2.09 3/15/20224,740,000 shares $9.24 million -2.1%N/A6.8 $1.95 2/28/20224,840,000 shares $10.02 million +8.3%N/A6.8 $2.07 2/15/20224,470,000 shares $13.50 million +17.6%N/A7 $3.02 1/31/20223,800,000 shares $12.05 million +5.3%N/A5.9 $3.17 1/15/20223,610,000 shares $12.45 million +1.4%N/A5.6 $3.45 12/31/20213,560,000 shares $14.03 million +10.9%N/A5 $3.94 12/15/20213,210,000 shares $12.78 million -10.6%N/A4.3 $3.98 11/30/20213,590,000 shares $16.44 million -0.6%N/A4.9 $4.58 11/15/20213,610,000 shares $18.59 million +8.4%N/A4.1 $5.15 10/29/20213,330,000 shares $17.62 million -2.4%2.4%3.5 $5.29 10/15/20213,410,000 shares $21.01 million -2.9%2.4%3.6 $6.16 9/30/20213,510,000 shares $16.88 million -4.6%2.5%3.8 $4.81Top Picks for Trump’s Pro-Crypto America (Ad)Mark August 12th on your calendar. 27 of crypto's most successful minds are about to reveal everything…Claim your pass to the Crypto Community Summit here (free for a limited time) 9/15/20213,680,000 shares $16.71 million -11.1%2.6%3.4 $4.54 8/31/20214,140,000 shares $19.54 million +16.6%3.0%4 $4.72 8/13/20213,550,000 shares $12.89 million -8.5%2.5%4 $3.63 7/30/20213,880,000 shares $13.74 million -3.2%2.8%4.7 $3.54 7/15/20214,010,000 shares $14.80 million -8.2%2.9%4.9 $3.69 6/30/20214,370,000 shares $20.06 million +24.2%3.1%5.2 $4.59 6/15/20213,520,000 shares $16.68 million -3.3%2.5%5.3 $4.74 5/28/20213,640,000 shares $15.98 million -9.0%2.6%4.7 $4.39 5/14/20214,000,000 shares $16.80 million -5.7%N/A4.5 $4.20 4/30/20214,240,000 shares $21.37 million -5.4%N/A3.9 $5.04 4/15/20214,480,000 shares $23.25 million +20.1%N/A2.9 $5.19 3/31/20213,730,000 shares $21.15 million -24.0%N/A0.8 $5.67 3/15/20214,910,000 shares $33.73 million +36.8%N/A0.9 $6.87 2/26/20213,590,000 shares $26.85 million -20.0%N/A0.4 $7.48 2/12/20214,490,000 shares $35.96 million -16.2%N/A0.5 $8.01 1/29/20215,360,000 shares $43.20 million -52.9%N/A0.5 $8.06 1/15/202111,380,000 shares $91.61 million -5.1%N/A1 $8.05 12/31/202011,990,000 shares $39.69 million -2.0%N/A1.6 $3.31 12/15/202012,240,000 shares $36.48 million +29.0%N/A1.7 $2.98 11/30/20209,490,000 shares $15.37 million -1.7%N/A1.6 $1.62 11/15/20209,650,000 shares $12.26 million -0.4%N/A3.7 $1.27 10/30/20209,690,000 shares $11.24 million +3.1%N/A11.7 $1.16 10/15/20209,400,000 shares $13.63 million -7.2%9.1%7.7 $1.45 9/30/202010,130,000 shares $14.59 million -14.4%9.8%5.9 $1.44 9/15/202011,830,000 shares $18.81 million -13.0%11.5%7.1 $1.59 8/31/202013,590,000 shares $23.78 million -9.4%13.2%7.9 $1.75 8/14/202015,000,000 shares $27.15 million -8.9%14.5%8.6 $1.81 7/31/202016,460,000 shares $31.93 million +44.8%15.9%9.5 $1.94 7/15/202011,370,000 shares $22.29 million +9.3%11.0%8.2 $1.96 LXRX Short Interest - Frequently Asked Questions What is Lexicon Pharmaceuticals' current short interest? Short interest is the volume of Lexicon Pharmaceuticals shares that have been sold short but have not yet been covered or closed out. As of June 15th, traders have sold 37,560,000 shares of LXRX short. 12.07% of Lexicon Pharmaceuticals' shares are currently sold short. Learn More on Lexicon Pharmaceuticals' current short interest. What is a good short interest ratio for Lexicon Pharmaceuticals? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. LXRX shares currently have a short interest ratio of 3.0. Learn More on Lexicon Pharmaceuticals's short interest ratio. Which institutional investors are shorting Lexicon Pharmaceuticals? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of Lexicon Pharmaceuticals: Simplex Trading LLC. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. What is a good short interest percentage for Lexicon Pharmaceuticals? Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 12.07% of Lexicon Pharmaceuticals' floating shares are currently sold short. Is Lexicon Pharmaceuticals' short interest increasing or decreasing? Lexicon Pharmaceuticals saw a decrease in short interest in June. As of June 15th, there was short interest totaling 37,560,000 shares, a decrease of 3.3% from the previous total of 38,830,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. How does Lexicon Pharmaceuticals' short interest compare to its competitors? 12.07% of Lexicon Pharmaceuticals' shares are currently sold short. Here is how the short interest of companies in the industry of "biotechnology" compare to Lexicon Pharmaceuticals: Novavax, Inc. (27.74%), OPKO Health, Inc. (8.85%), Geron Corporation (11.06%), Regulus Therapeutics Inc. (3.07%), Myriad Genetics, Inc. (9.31%), Emergent Biosolutions Inc. (15.39%), Rigel Pharmaceuticals, Inc. (12.09%), XOMA Royalty Corporation (1.54%), Vanda Pharmaceuticals Inc. (8.62%), Verastem, Inc. (24.92%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: SPDR S&P 500 ETF Trust ($69.26 billion), Invesco QQQ ($25.22 billion), iShares Russell 2000 ETF ($20.33 billion), iShares 20+ Year Treasury Bond ETF ($9.99 billion), MicroStrategy Incorporated ($9.12 billion), Canadian Natural Resources Limited ($6.73 billion), SPDR S&P Biotech ETF ($6.52 billion), Invesco S&P 500 Equal Weight ETF ($5.60 billion), Financial Select Sector SPDR Fund ($4.64 billion), and iShares iBoxx $ Investment Grade Corporate Bond ETF ($4.59 billion). View all of the most shorted stocks. What does it mean to sell short Lexicon Pharmaceuticals stock? Short selling LXRX is an investing strategy that aims to generate trading profit from Lexicon Pharmaceuticals as its price is falling. LXRX shares are trading up $0.12 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Lexicon Pharmaceuticals? A short squeeze for Lexicon Pharmaceuticals occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of LXRX, which in turn drives the price of the stock up even further. How often is Lexicon Pharmaceuticals' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including LXRX, twice per month. The most recent reporting period available is June, 15 2025. More Short Interest Resources from MarketBeat Related Companies NVAX Short Interest Data OPK Short Interest Data GERN Short Interest Data RGLS Short Interest Data MYGN Short Interest Data EBS Short Interest Data RIGL Short Interest Data XOMA Short Interest Data VNDA Short Interest Data VSTM Short Interest Data Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:LXRX) was last updated on 7/1/2025 by MarketBeat.com Staff From Our PartnersNvidia’s Huang: AI is going to need 100x more power12Nvidia CEO Jensen Huang didn't mince words. 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