| 2/19/2025 | Public Employees Retirement System of Ohio | 99,307 | $64K | 0.0% | N/A | 0.034% | |
| 2/17/2025 | venBio Partners LLC | 7,102,190 | $4.55M | 2.7% | N/A | 2.431% | |
| 2/17/2025 | Two Sigma Investments LP | 204,501 | $131K | 0.0% | -15.4% | 0.070% | |
| 2/17/2025 | Two Sigma Advisers LP | 306,400 | $196K | 0.0% | +143.8% | 0.105% | |
| 2/17/2025 | Nuveen Asset Management LLC | 641,173 | $410K | 0.0% | -25.1% | 0.219% | |
| 2/17/2025 | Orbimed Advisors LLC | 3,103,623 | $1.99M | 0.0% | -49.0% | 1.062% | |
| 2/17/2025 | Millennium Management LLC | 957,507 | $613K | 0.0% | +34.8% | 0.328% | |
| 2/17/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 308,551 | $197K | 0.0% | +13.4% | 0.106% | |
| 2/17/2025 | Jacobs Levy Equity Management Inc. | 1,385,301 | $887K | 0.0% | N/A | 0.474% | |
| 2/17/2025 | Graham Capital Management L.P. | 52,136 | $33K | 0.0% | N/A | 0.018% | |
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| 2/17/2025 | Foresite Capital Management V LLC | 8,133,047 | $5.21M | 4.3% | N/A | 2.784% | |
| 2/17/2025 | D. E. Shaw & Co. Inc. | 966,265 | $618K | 0.0% | +104.4% | 0.331% | |
| 2/17/2025 | BNP Paribas Financial Markets | 253,669 | $162K | 0.0% | N/A | 0.087% | |
| 2/17/2025 | Almitas Capital LLC | 1,050,520 | $672K | 0.1% | N/A | 0.360% | |
| 2/14/2025 | Jane Street Group LLC | 239,439 | $153K | 0.0% | -16.8% | 0.082% | |
| 2/14/2025 | Northern Trust Corp | 1,310,224 | $839K | 0.0% | -3.4% | 0.448% | |
| 2/14/2025 | Decheng Capital LLC | 11,909,341 | $7.62M | 1.6% | N/A | 4.076% | |
| 2/14/2025 | Boothbay Fund Management LLC | 406,234 | $260K | 0.0% | +190.4% | 0.139% | |
| 2/14/2025 | Price T Rowe Associates Inc. MD | 6,910,749 | $4.42M | 0.0% | -6.0% | 2.365% | |
| 2/14/2025 | Johnson & Johnson | 823,317 | $527K | 0.1% | N/A | 0.282% | |
| 2/13/2025 | Barclays PLC | 258,380 | $165K | 0.0% | +7.4% | 0.088% | |
| 2/13/2025 | Renaissance Technologies LLC | 1,612,146 | $1.03M | 0.0% | +716.7% | 0.552% | |
| 2/13/2025 | Wells Fargo & Company MN | 94,320 | $60K | 0.0% | +27.8% | 0.032% | |
| 2/12/2025 | RPO LLC | 66,378 | $42K | 0.0% | N/A | 0.023% | |
| 2/12/2025 | Geode Capital Management LLC | 4,137,264 | $2.65M | 0.0% | +2.9% | 1.416% | |
| 2/12/2025 | Takeda Pharmaceutical Co. Ltd. | 823,317 | $527K | 2.0% | N/A | 0.282% | |
| 2/12/2025 | JPMorgan Chase & Co. | 433,265 | $277K | 0.0% | +347.8% | 0.148% | |
| 2/11/2025 | Prudential Financial Inc. | 48,057 | $31K | 0.0% | -66.8% | 0.016% | |
| 2/6/2025 | Charles Schwab Investment Management Inc. | 1,645,787 | $1.05M | 0.0% | +43.4% | 0.563% | |
| 1/17/2025 | SG Americas Securities LLC | 116,748 | $75K | 0.0% | +102.8% | 0.040% | |
| 11/19/2024 | Barclays PLC | 240,615 | $332K | 0.0% | +312.7% | 0.082% | |
| 11/15/2024 | Barclays PLC | 240,615 | $332K | 0.0% | +312.7% | 0.086% | |
| 11/15/2024 | Jane Street Group LLC | 287,717 | $397K | 0.0% | +63.7% | 0.103% | |
| 11/15/2024 | State Street Corp | 3,889,553 | $5.37M | 0.0% | +1.9% | 1.393% | |
| 11/15/2024 | Centiva Capital LP | 22,160 | $31K | 0.0% | N/A | 0.008% | |
| 11/15/2024 | Point72 Asia Singapore Pte. Ltd. | 37,704 | $52K | 0.0% | N/A | 0.014% | |
| 11/15/2024 | Erste Asset Management GmbH | 54,000 | $82K | 0.0% | N/A | 0.019% | |
| 11/14/2024 | MetLife Investment Management LLC | 36,287 | $50K | 0.0% | -57.5% | 0.013% | |
| 11/13/2024 | FMR LLC | 1,024,583 | $1.41M | 0.0% | -62.5% | 0.367% | |
| 11/12/2024 | Charles Schwab Investment Management Inc. | 1,147,370 | $1.58M | 0.0% | -11.6% | 0.448% | |
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| 11/9/2024 | Intech Investment Management LLC | 37,495 | $52K | 0.0% | N/A | 0.015% | |
| 11/8/2024 | WuXi AppTec Co. Ltd. | 7,390,710 | $10.20M | 53.6% | -3.8% | 2.887% | |
| 11/6/2024 | Cornercap Investment Counsel Inc. | 47,763 | $66K | 0.0% | -50.4% | 0.019% | |
| 11/5/2024 | Baillie Gifford & Co. | 141,949 | $196K | 0.0% | -72.7% | 0.055% | |
| 11/5/2024 | GSA Capital Partners LLP | 354,815 | $490K | 0.0% | +1,285.5% | 0.139% | |
| 10/25/2024 | China Universal Asset Management Co. Ltd. | 49,238 | $68K | 0.0% | +64.4% | 0.019% | |
| 10/10/2024 | Exchange Traded Concepts LLC | 135,050 | $186K | 0.0% | +37.3% | 0.053% | |
| 10/3/2024 | SG Americas Securities LLC | 57,566 | $79K | 0.0% | +78.1% | 0.023% | |
| 8/15/2024 | Susquehanna Fundamental Investments LLC | 128,203 | $186K | 0.0% | +49.5% | 0.050% | |
| 8/15/2024 | The Manufacturers Life Insurance Company | 553,163 | $802K | 0.0% | +14.4% | 0.217% | |
| 8/14/2024 | ProShare Advisors LLC | 38,982 | $57K | 0.0% | -20.4% | 0.015% | |
| 8/12/2024 | XTX Topco Ltd | 70,174 | $102K | 0.0% | -36.6% | 0.028% | |
| 8/9/2024 | Renaissance Technologies LLC | 152,300 | $221K | 0.0% | -64.0% | 0.060% | |
| 8/9/2024 | Dimensional Fund Advisors LP | 40,098 | $58K | 0.0% | +197.8% | 0.016% | |
| 8/9/2024 | Massachusetts Financial Services Co. MA | 577,319 | $837K | 0.0% | -62.5% | 0.226% | |
| 8/8/2024 | American Century Companies Inc. | 279,425 | $405K | 0.0% | +18.1% | 0.110% | |
| 8/6/2024 | WuXi AppTec Co. Ltd. | 7,682,156 | $11.14M | 47.7% | -6.1% | 3.013% | |
| 8/3/2024 | TD Asset Management Inc | 1,004,642 | $1.46M | 0.0% | +4.2% | 0.394% | |
| 8/1/2024 | Rhumbline Advisers | 260,742 | $378K | 0.0% | -6.3% | 0.102% | |
| 7/29/2024 | Principal Financial Group Inc. | 26,510 | $38K | 0.0% | -54.5% | 0.010% | |
| 7/26/2024 | Bank of New York Mellon Corp | 671,966 | $974K | 0.0% | +6.1% | 0.264% | |
| 7/25/2024 | Baillie Gifford & Co. | 519,998 | $754K | 0.0% | -20.8% | 0.204% | |
| 7/12/2024 | SG Americas Securities LLC | 32,319 | $47K | 0.0% | -52.7% | 0.013% | |
| 7/10/2024 | Simplicity Wealth LLC | 18,412 | $27K | 0.0% | -28.8% | 0.007% | |
| 5/29/2024 | Opaleye Management Inc. | 3,355,000 | $7.48M | 1.6% | N/A | 1.316% | |
| 5/16/2024 | California State Teachers Retirement System | 130,581 | $291K | 0.0% | -6.8% | 0.051% | |
| 5/16/2024 | Invenomic Capital Management LP | 871,525 | $1.94M | 0.1% | +16.8% | 0.342% | |
| 5/16/2024 | Jacobs Levy Equity Management Inc. | 28,584 | $64K | 0.0% | N/A | 0.011% | |
| 5/16/2024 | Caxton Associates LP | 174,657 | $389K | 0.0% | +359.1% | 0.069% | |
| 5/15/2024 | Price T Rowe Associates Inc. MD | 6,731,477 | $15.01M | 0.0% | +1.4% | 2.640% | |
| 5/14/2024 | EntryPoint Capital LLC | 26,727 | $60K | 0.1% | -59.3% | 0.010% | |
| 5/14/2024 | Shell Asset Management Co. | 138,958 | $310K | 0.0% | -3.5% | 0.055% | |
| 5/10/2024 | Acadian Asset Management LLC | 77,952 | $173K | 0.0% | N/A | 0.031% | |
| 5/10/2024 | Vanguard Group Inc. | 13,388,425 | $29.86M | 0.0% | -1.6% | 5.252% | |
| 5/9/2024 | State Board of Administration of Florida Retirement System | 32,253 | $76K | 0.0% | -34.9% | 0.013% | |
| 5/8/2024 | Bleakley Financial Group LLC | 25,842 | $58K | 0.0% | -46.3% | 0.010% | |
| 5/8/2024 | ProShare Advisors LLC | 48,986 | $109K | 0.0% | +9.3% | 0.019% | |
| 5/7/2024 | Susquehanna Fundamental Investments LLC | 85,751 | $191K | 0.0% | N/A | 0.034% | |
| 5/7/2024 | SG Americas Securities LLC | 68,265 | $152K | 0.0% | -31.2% | 0.027% | |
| 5/1/2024 | Baillie Gifford & Co. | 656,157 | $1.46M | 0.0% | -5.0% | 0.257% | |
| 4/29/2024 | Principal Financial Group Inc. | 58,254 | $130K | 0.0% | -7.4% | 0.023% | |
| 4/29/2024 | China Universal Asset Management Co. Ltd. | 48,855 | $109K | 0.0% | +67.7% | 0.019% | |
| 4/24/2024 | Simplicity Wealth LLC | 25,842 | $58K | 0.0% | N/A | 0.010% | |
| 2/14/2024 | Invenomic Capital Management LP | 746,415 | $1.45M | 0.1% | N/A | 0.296% | |
| 2/12/2024 | RPO LLC | 19,739 | $38K | 0.1% | N/A | 0.008% | |
| 2/8/2024 | Vanguard Personalized Indexing Management LLC | 15,917 | $31K | 0.0% | N/A | 0.006% | |
| 2/8/2024 | Massachusetts Financial Services Co. MA | 1,354,678 | $2.63M | 0.0% | -0.6% | 0.538% | |
| 2/7/2024 | Teacher Retirement System of Texas | 29,018 | $56K | 0.0% | -18.2% | 0.012% | |
| 2/6/2024 | WuXi AppTec Co. Ltd. | 8,180,678 | $15.87M | 41.2% | N/A | 3.248% | |
| 2/6/2024 | Swiss National Bank | 247,400 | $480K | 0.0% | -8.9% | 0.098% | |
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| 1/30/2024 | Zurcher Kantonalbank Zurich Cantonalbank | 29,918 | $58K | 0.0% | -18.1% | 0.012% | |
| 1/29/2024 | Simplicity Solutions LLC | 48,108 | $93K | 0.0% | N/A | 0.019% | |
| 1/26/2024 | Baillie Gifford & Co. | 690,871 | $1.34M | 0.0% | -5.7% | 0.274% | |
| 1/25/2024 | Bleakley Financial Group LLC | 48,108 | $93K | 0.0% | N/A | 0.019% | |
| 1/24/2024 | Mirae Asset Global Investments Co. Ltd. | 225,506 | $437K | 0.0% | +1,052.7% | 0.090% | |
| 1/24/2024 | China Universal Asset Management Co. Ltd. | 29,137 | $57K | 0.0% | +352.7% | 0.012% | |
| 1/12/2024 | SG Americas Securities LLC | 99,221 | $192K | 0.0% | +81.9% | 0.039% | |
| 1/5/2024 | Exchange Traded Concepts LLC | 82,956 | $161K | 0.0% | +34.0% | 0.033% | |
| 12/19/2023 | Public Employees Retirement System of Ohio | 27,203 | $40K | 0.0% | +109.7% | 0.011% | |
| 12/18/2023 | Vanguard Group Inc. | 16,909,720 | $24.86M | 0.0% | +0.2% | 6.714% | |
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