| 2/25/2025 | Polar Asset Management Partners Inc. | 99,100 | $1.22M | 0.0% | +144.7% | 0.199% | |
| 2/17/2025 | Tema Etfs LLC | 89,529 | $1.10M | 0.5% | N/A | 0.180% | |
| 2/17/2025 | Stempoint Capital LP | 400,101 | $4.93M | 1.2% | N/A | 0.804% | |
| 2/17/2025 | Sphera Funds Management LTD. | 190,672 | $2.35M | 0.4% | -30.0% | 0.383% | |
| 2/17/2025 | Polar Asset Management Partners Inc. | 99,100 | $1.22M | 0.0% | +144.7% | 0.199% | |
| 2/17/2025 | ProShare Advisors LLC | 10,405 | $128K | 0.0% | N/A | 0.021% | |
| 2/17/2025 | OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC | 28,068 | $346K | 0.0% | -9.7% | 0.056% | |
| 2/17/2025 | Orbimed Advisors LLC | 1,611,637 | $19.84M | 0.4% | -19.5% | 3.238% | |
| 2/17/2025 | Millennium Management LLC | 1,101,674 | $13.56M | 0.0% | +1,015.8% | 2.214% | |
| 2/17/2025 | Letko Brosseau & Associates Inc. | 16,500 | $203K | 0.0% | +44.7% | 0.033% | |
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| 2/17/2025 | Integral Health Asset Management LLC | 875,000 | $10.77M | 0.9% | +145.8% | 1.758% | |
| 2/17/2025 | Deutsche Bank AG | 26,732 | $329K | 0.0% | +62.3% | 0.054% | |
| 2/17/2025 | Balyasny Asset Management L.P. | 17,786 | $219K | 0.0% | N/A | 0.036% | |
| 2/17/2025 | Bank of America Corp DE | 107,703 | $1.33M | 0.0% | +12.0% | 0.216% | |
| 2/17/2025 | BNP Paribas Financial Markets | 3,895 | $48K | 0.0% | N/A | 0.008% | |
| 2/17/2025 | Adams Street Partners LLC | 1,129,807 | $13.91M | 12.3% | -26.3% | 2.270% | |
| 2/14/2025 | Caligan Partners LP | 1,011,155 | $12.45M | 3.3% | +3.1% | 2.032% | |
| 2/14/2025 | Northern Trust Corp | 246,113 | $3.03M | 0.0% | +0.7% | 0.495% | |
| 2/14/2025 | Boothbay Fund Management LLC | 650,023 | $8.00M | 0.2% | +7.3% | 1.306% | |
| 2/14/2025 | Virtus ETF Advisers LLC | 5,842 | $72K | 0.0% | -19.6% | 0.012% | |
| 2/14/2025 | Price T Rowe Associates Inc. MD | 11,715 | $145K | 0.0% | N/A | 0.024% | |
| 2/14/2025 | Dimensional Fund Advisors LP | 16,412 | $202K | 0.0% | N/A | 0.033% | |
| 2/13/2025 | Barclays PLC | 46,396 | $571K | 0.0% | +21.4% | 0.093% | |
| 2/13/2025 | Renaissance Technologies LLC | 119,500 | $1.47M | 0.0% | +15.1% | 0.240% | |
| 2/13/2025 | ADAR1 Capital Management LLC | 841,541 | $10.36M | 2.1% | +15.4% | 1.691% | |
| 2/13/2025 | Federated Hermes Inc. | 15,516 | $191K | 0.0% | -7.9% | 0.031% | |
| 2/13/2025 | Wells Fargo & Company MN | 23,714 | $292K | 0.0% | +19.1% | 0.048% | |
| 2/12/2025 | Wellington Management Group LLP | 91,529 | $1.13M | 0.0% | +43.0% | 0.184% | |
| 2/12/2025 | NEOS Investment Management LLC | 89,529 | $1.10M | 0.0% | -27.5% | 0.180% | |
| 2/12/2025 | JPMorgan Chase & Co. | 503,590 | $6.20M | 0.0% | +2,251.5% | 1.012% | |
| 2/11/2025 | EntryPoint Capital LLC | 12,487 | $154K | 0.1% | N/A | 0.025% | |
| 2/11/2025 | Prudential Financial Inc. | 125,650 | $1.55M | 0.0% | +85.7% | 0.252% | |
| 2/11/2025 | Corebridge Financial Inc. | 14,197 | $175K | 0.0% | -7.0% | 0.029% | |
| 2/11/2025 | Vanguard Group Inc. | 1,432,042 | $17.63M | 0.0% | +5.0% | 2.877% | |
| 2/11/2025 | American Century Companies Inc. | 848,630 | $10.45M | 0.0% | -8.9% | 1.705% | |
| 2/7/2025 | AlphaQuest LLC | 15,222 | $187K | 0.0% | +2,637.8% | 0.031% | |
| 2/7/2025 | Candriam S.C.A. | 305,272 | $3.76M | 0.0% | N/A | 0.613% | |
| 2/6/2025 | Proficio Capital Partners LLC | 23,192 | $285K | 0.0% | N/A | 0.047% | |
| 2/6/2025 | Charles Schwab Investment Management Inc. | 214,906 | $2.65M | 0.0% | +0.6% | 0.432% | |
| 2/5/2025 | Proficio Capital Partners LLC | 23,192 | $285K | 0.0% | N/A | 0.047% | |
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| 2/4/2025 | Bank of New York Mellon Corp | 65,318 | $804K | 0.0% | +2.7% | 0.131% | |
| 1/24/2025 | Jennison Associates LLC | 1,082,006 | $13.32M | 0.0% | +55.4% | 2.174% | |
| 1/24/2025 | China Universal Asset Management Co. Ltd. | 10,553 | $130K | 0.0% | +10.3% | 0.021% | |
| 1/17/2025 | SG Americas Securities LLC | 19,961 | $246K | 0.0% | +119.0% | 0.040% | |
| 11/27/2024 | Franklin Resources Inc. | 1,745,513 | $21.14M | 0.0% | +17.7% | 3.507% | |
| 11/19/2024 | Barclays PLC | 38,218 | $463K | 0.0% | +281.8% | 0.077% | |
| 11/16/2024 | Geode Capital Management LLC | 620,853 | $7.52M | 0.0% | +6.6% | 1.247% | |
| 11/15/2024 | Barclays PLC | 38,218 | $463K | 0.0% | +281.8% | 0.077% | |
| 11/15/2024 | Jane Street Group LLC | 15,855 | $192K | 0.0% | -30.4% | 0.032% | |
| 11/15/2024 | Wellington Management Group LLP | 63,998 | $775K | 0.0% | N/A | 0.129% | |
| 11/15/2024 | Sphera Funds Management LTD. | 272,472 | $3.30M | 0.5% | -38.5% | 0.547% | |
| 11/15/2024 | State Street Corp | 483,766 | $5.86M | 0.0% | +4.0% | 0.972% | |
| 11/15/2024 | Polar Asset Management Partners Inc. | 40,500 | $490K | 0.0% | N/A | 0.081% | |
| 11/15/2024 | Ikarian Capital LLC | 180,000 | $2.18M | 0.3% | N/A | 0.362% | |
| 11/14/2024 | Bellevue Group AG | 16,499 | $200K | 0.0% | -5.7% | 0.033% | |
| 11/14/2024 | Caligan Partners LP | 981,155 | $11.88M | 3.8% | +31.6% | 1.973% | |
| 11/14/2024 | PDT Partners LLC | 12,238 | $148K | 0.0% | N/A | 0.025% | |
| 11/14/2024 | Verition Fund Management LLC | 27,361 | $331K | 0.0% | +30.6% | 0.055% | |
| 11/14/2024 | Martingale Asset Management L P | 14,965 | $181K | 0.0% | N/A | 0.030% | |
| 11/13/2024 | FMR LLC | 303,758 | $3.68M | 0.0% | +12.0% | 0.611% | |
| 11/12/2024 | Charles Schwab Investment Management Inc. | 213,599 | $2.59M | 0.0% | +4.7% | 0.430% | |
| 11/8/2024 | Jennison Associates LLC | 696,280 | $8.43M | 0.0% | +1.9% | 1.400% | |
| 10/25/2024 | China Universal Asset Management Co. Ltd. | 9,564 | $116K | 0.0% | +64.0% | 0.019% | |
| 10/3/2024 | SG Americas Securities LLC | 9,116 | $110K | 0.0% | N/A | 0.018% | |
| 8/20/2024 | Nantahala Capital Management LLC | 532,506 | $6.23M | 0.4% | +60.1% | 1.073% | |
| 8/16/2024 | Driehaus Capital Management LLC | 257,371 | $3.01M | 0.0% | +40.4% | 0.518% | |
| 8/15/2024 | Blue Owl Capital Holdings LP | 450,339 | $5.27M | 1.5% | -16.8% | 0.907% | |
| 8/15/2024 | Lion Point Capital LP | 79,000 | $924K | 1.7% | +31.7% | 0.159% | |
| 8/15/2024 | The Manufacturers Life Insurance Company | 12,432 | $145K | 0.0% | N/A | 0.025% | |
| 8/14/2024 | Adams Street Partners LLC | 1,688,712 | $19.76M | 8.1% | -10.0% | 3.401% | |
| 8/9/2024 | Renaissance Technologies LLC | 61,800 | $723K | 0.0% | +95.0% | 0.124% | |
| 8/8/2024 | Federated Hermes Inc. | 12,000 | $140K | 0.0% | +100.0% | 0.024% | |
| 8/8/2024 | American Century Companies Inc. | 743,140 | $8.70M | 0.0% | +3.2% | 1.497% | |
| 8/1/2024 | Rhumbline Advisers | 41,079 | $481K | 0.0% | +82.1% | 0.083% | |
| 7/26/2024 | Bank of New York Mellon Corp | 84,762 | $992K | 0.0% | +72.5% | 0.171% | |
| 5/17/2024 | RA Capital Management L.P. | 4,850,984 | $62.63M | 0.8% | +52.6% | 9.770% | |
| 5/16/2024 | California State Teachers Retirement System | 1,953 | $25K | 0.0% | -38.9% | 0.004% | |
| 5/15/2024 | Bellevue Group AG | 9,200 | $119K | 0.0% | N/A | 0.019% | |
| 5/15/2024 | Affinity Asset Advisors LLC | 327,959 | $4.23M | 0.5% | N/A | 0.661% | |
| 5/14/2024 | EntryPoint Capital LLC | 4,632 | $60K | 0.1% | -30.4% | 0.009% | |
| 5/14/2024 | SR One Capital Management LP | 2,016,822 | $26.04M | 7.2% | +12.4% | 4.062% | |
| 5/10/2024 | Vanguard Group Inc. | 982,932 | $12.69M | 0.0% | +0.5% | 1.980% | |
| 4/29/2024 | China Universal Asset Management Co. Ltd. | 7,931 | $102K | 0.0% | +67.0% | 0.016% | |
| 3/22/2024 | PNC Financial Services Group Inc. | 4,122 | $35K | 0.0% | +17,821.7% | 0.010% | |
| 2/14/2024 | Catalys Pacific LLC | 9,194,579 | $79.07M | 74.1% | N/A | 22.371% | |
| 2/14/2024 | Pale Fire Capital SE | 34,743 | $299K | 0.0% | N/A | 0.085% | |
| 2/14/2024 | Sectoral Asset Management Inc. | 605,606 | $5.21M | 2.2% | -28.0% | 1.473% | |
| 2/13/2024 | Tower Research Capital LLC TRC | 2,879 | $25K | 0.0% | -71.4% | 0.007% | |
| 2/13/2024 | NEOS Investment Management LLC | 23,973 | $206K | 0.0% | N/A | 0.058% | |
| 2/9/2024 | Franklin Resources Inc. | 699,467 | $6.02M | 0.0% | +55.4% | 1.702% | |
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| 2/9/2024 | CreativeOne Wealth LLC | 10,750 | $92K | 0.0% | N/A | 0.026% | |
| 2/7/2024 | Jump Financial LLC | 20,500 | $176K | 0.0% | -37.3% | 0.050% | |
| 2/5/2024 | Russell Investments Group Ltd. | 5,779 | $50K | 0.0% | -43.2% | 0.014% | |
| 2/1/2024 | CWM LLC | 5,891 | $51K | 0.0% | +120.0% | 0.014% | |
| 1/31/2024 | Federated Hermes Inc. | 20,032 | $172K | 0.0% | -10.1% | 0.049% | |
| 1/30/2024 | Cornercap Investment Counsel Inc. | 22,209 | $191K | 0.0% | N/A | 0.054% | |
| 1/24/2024 | China Universal Asset Management Co. Ltd. | 4,750 | $41K | 0.0% | N/A | 0.012% | |
| 1/16/2024 | Raymond James Financial Services Advisors Inc. | 14,611 | $126K | 0.0% | -64.0% | 0.036% | |
| 1/12/2024 | SG Americas Securities LLC | 10,093 | $87K | 0.0% | N/A | 0.025% | |
| 11/15/2023 | Sectoral Asset Management Inc. | 840,759 | $8.00M | 1.6% | +36.8% | 2.046% | |
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