NGNE vs. SYRE, MLYS, AVDL, PHVS, NRIX, ARDX, ORIC, PRAX, ZYME, and LENZ
Should you be buying Neurogene stock or one of its competitors? The main competitors of Neurogene include Spyre Therapeutics (SYRE), Mineralys Therapeutics (MLYS), Avadel Pharmaceuticals (AVDL), Pharvaris (PHVS), Nurix Therapeutics (NRIX), Ardelyx (ARDX), Oric Pharmaceuticals (ORIC), Praxis Precision Medicines (PRAX), Zymeworks (ZYME), and LENZ Therapeutics (LENZ). These companies are all part of the "pharmaceutical products" industry.
Neurogene vs. Its Competitors
Neurogene (NASDAQ:NGNE) and Spyre Therapeutics (NASDAQ:SYRE) are both small-cap medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their valuation, media sentiment, risk, earnings, analyst recommendations, dividends, institutional ownership and profitability.
Neurogene currently has a consensus target price of $46.17, indicating a potential upside of 130.32%. Spyre Therapeutics has a consensus target price of $53.40, indicating a potential upside of 237.12%. Given Spyre Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Spyre Therapeutics is more favorable than Neurogene.
Neurogene has a beta of 1.51, meaning that its stock price is 51% more volatile than the S&P 500. Comparatively, Spyre Therapeutics has a beta of 2.68, meaning that its stock price is 168% more volatile than the S&P 500.
Neurogene's return on equity of -36.16% beat Spyre Therapeutics' return on equity.
Neurogene has higher revenue and earnings than Spyre Therapeutics. Neurogene is trading at a lower price-to-earnings ratio than Spyre Therapeutics, indicating that it is currently the more affordable of the two stocks.
In the previous week, Neurogene had 8 more articles in the media than Spyre Therapeutics. MarketBeat recorded 10 mentions for Neurogene and 2 mentions for Spyre Therapeutics. Neurogene's average media sentiment score of 0.18 beat Spyre Therapeutics' score of 0.00 indicating that Neurogene is being referred to more favorably in the media.
52.4% of Neurogene shares are held by institutional investors. Comparatively, 80.4% of Spyre Therapeutics shares are held by institutional investors. 9.9% of Neurogene shares are held by insiders. Comparatively, 6.2% of Spyre Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.
Summary
Spyre Therapeutics beats Neurogene on 8 of the 15 factors compared between the two stocks.
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New MarketBeat Followers Over Time
This chart shows the number of new MarketBeat users adding NGNE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
Media Sentiment Over Time
This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
Neurogene Competitors List
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This page (NASDAQ:NGNE) was last updated on 7/7/2025 by MarketBeat.com Staff
