OPKO Health (OPK) Competitors $1.44 +0.02 (+1.41%) Closing price 04:00 PM EasternExtended Trading$1.46 +0.02 (+1.39%) As of 05:32 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock OPK vs. FOLD, LGND, DVAX, MNKD, BCRX, INVA, CLDX, NVAX, GERN, and MYGNShould you be buying OPKO Health stock or one of its competitors? The main competitors of OPKO Health include Amicus Therapeutics (FOLD), Ligand Pharmaceuticals (LGND), Dynavax Technologies (DVAX), MannKind (MNKD), BioCryst Pharmaceuticals (BCRX), Innoviva (INVA), Celldex Therapeutics (CLDX), Novavax (NVAX), Geron (GERN), and Myriad Genetics (MYGN). These companies are all part of the "biotechnology" industry. OPKO Health vs. Amicus Therapeutics Ligand Pharmaceuticals Dynavax Technologies MannKind BioCryst Pharmaceuticals Innoviva Celldex Therapeutics Novavax Geron Myriad Genetics OPKO Health (NASDAQ:OPK) and Amicus Therapeutics (NASDAQ:FOLD) are both medical companies, but which is the superior business? We will contrast the two companies based on the strength of their dividends, valuation, earnings, community ranking, profitability, media sentiment, analyst recommendations, risk and institutional ownership. Does the media refer more to OPK or FOLD? In the previous week, OPKO Health had 6 more articles in the media than Amicus Therapeutics. MarketBeat recorded 17 mentions for OPKO Health and 11 mentions for Amicus Therapeutics. Amicus Therapeutics' average media sentiment score of 1.00 beat OPKO Health's score of 0.99 indicating that Amicus Therapeutics is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment OPKO Health 5 Very Positive mention(s) 1 Positive mention(s) 5 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Amicus Therapeutics 6 Very Positive mention(s) 0 Positive mention(s) 2 Neutral mention(s) 2 Negative mention(s) 0 Very Negative mention(s) Positive Do institutionals and insiders hold more shares of OPK or FOLD? 64.6% of OPKO Health shares are held by institutional investors. 49.7% of OPKO Health shares are held by company insiders. Comparatively, 2.2% of Amicus Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term. Is OPK or FOLD more profitable? Amicus Therapeutics has a net margin of -10.62% compared to OPKO Health's net margin of -18.65%. Amicus Therapeutics' return on equity of 12.44% beat OPKO Health's return on equity.Company Net Margins Return on Equity Return on Assets OPKO Health-18.65% -9.76% -6.46% Amicus Therapeutics -10.62%12.44%2.60% Do analysts prefer OPK or FOLD? OPKO Health currently has a consensus price target of $2.75, indicating a potential upside of 93.66%. Amicus Therapeutics has a consensus price target of $16.75, indicating a potential upside of 149.26%. Given Amicus Therapeutics' higher probable upside, analysts clearly believe Amicus Therapeutics is more favorable than OPKO Health.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score OPKO Health 0 Sell rating(s) 0 Hold rating(s) 3 Buy rating(s) 0 Strong Buy rating(s) 3.00Amicus Therapeutics 0 Sell rating(s) 2 Hold rating(s) 7 Buy rating(s) 0 Strong Buy rating(s) 2.78 Does the MarketBeat Community believe in OPK or FOLD? Amicus Therapeutics received 20 more outperform votes than OPKO Health when rated by MarketBeat users. Likewise, 72.98% of users gave Amicus Therapeutics an outperform vote while only 65.73% of users gave OPKO Health an outperform vote. CompanyUnderperformOutperformOPKO HealthOutperform Votes51265.73% Underperform Votes26734.27% Amicus TherapeuticsOutperform Votes53272.98% Underperform Votes19727.02% Which has more risk & volatility, OPK or FOLD? OPKO Health has a beta of 1.78, meaning that its stock price is 78% more volatile than the S&P 500. Comparatively, Amicus Therapeutics has a beta of 0.79, meaning that its stock price is 21% less volatile than the S&P 500. Which has stronger valuation and earnings, OPK or FOLD? Amicus Therapeutics has lower revenue, but higher earnings than OPKO Health. Amicus Therapeutics is trading at a lower price-to-earnings ratio than OPKO Health, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioOPKO Health$713.14M1.34-$188.86M-$0.09-15.78Amicus Therapeutics$528.30M3.91-$151.58M-$0.18-37.33 SummaryAmicus Therapeutics beats OPKO Health on 10 of the 18 factors compared between the two stocks. Remove Ads Get OPKO Health News Delivered to You Automatically Sign up to receive the latest news and ratings for OPK and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart OPK vs. The Competition Export to ExcelMetricOPKO HealthPharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$953.60M$6.35B$5.35B$7.58BDividend YieldN/A3.23%5.11%4.33%P/E Ratio-7.476.7721.7417.78Price / Sales1.34228.59376.0494.51Price / CashN/A65.6738.1534.64Price / Book0.795.886.443.99Net Income-$188.86M$141.32M$3.20B$247.24M7 Day Performance-2.74%8.32%6.19%6.12%1 Month Performance-18.39%-12.93%-8.79%-7.11%1 Year Performance15.45%-12.47%9.69%-0.85% OPKO Health Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)OPKOPKO Health4.1223 of 5 stars$1.44+1.4%$2.75+91.0%+15.4%$967.03M$713.14M-7.583,930Options VolumeFOLDAmicus Therapeutics4.0325 of 5 stars$7.12-5.1%$16.75+135.4%-37.1%$2.17B$528.30M-39.31480Positive NewsLGNDLigand Pharmaceuticals4.3479 of 5 stars$99.80+0.2%$147.00+47.3%+31.0%$1.91B$167.13M39.4380Analyst UpgradeNews CoveragePositive NewsDVAXDynavax Technologies4.3848 of 5 stars$12.52-1.0%$21.50+71.7%-3.4%$1.55B$277.25M69.47350Positive NewsGap DownMNKDMannKind2.2503 of 5 stars$4.68-1.4%$9.21+97.1%+11.6%$1.42B$285.50M66.79400Positive NewsGap DownBCRXBioCryst Pharmaceuticals4.1358 of 5 stars$6.77-1.0%$15.57+130.2%+47.6%$1.41B$450.71M-11.02530Gap DownINVAInnoviva4.3582 of 5 stars$17.45-1.5%$55.00+215.2%+22.9%$1.09B$358.71M25.25100Analyst UpgradeNews CoveragePositive NewsCLDXCelldex Therapeutics2.3225 of 5 stars$15.69-0.6%$54.33+246.2%-54.7%$1.04B$7.02M-6.08150News CoverageNVAXNovavax3.6196 of 5 stars$6.46+3.5%$18.00+178.7%+49.8%$1.03B$682.16M-2.851,990GERNGeron3.7688 of 5 stars$1.41+1.8%$5.75+309.3%-63.7%$888.48M$76.99M-4.3670Short Interest ↑MYGNMyriad Genetics3.8303 of 5 stars$8.06-0.9%$20.89+159.2%-58.7%$736.41M$837.60M-6.202,700 Remove Ads Related Companies and Tools Related Companies FOLD Competitors LGND Competitors DVAX Competitors MNKD Competitors BCRX Competitors INVA Competitors CLDX Competitors NVAX Competitors GERN Competitors MYGN Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:OPK) was last updated on 4/15/2025 by MarketBeat.com Staff From Our Partners[Action Required] Claim Your FREE IRS Loophole GuideThis shouldn't surprise anyone who's been paying attention, but... 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