Opthea (OPT) Competitors $3.41 0.00 (0.00%) As of 03/28/2025 Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsFinancialsHeadlinesOwnershipSEC FilingsShort InterestTrendsBuy This Stock OPT vs. HRMY, ARQT, JANX, TVTX, AGIO, TARS, APGE, VERA, IRON, and SDGRShould you be buying Opthea stock or one of its competitors? The main competitors of Opthea include Harmony Biosciences (HRMY), Arcutis Biotherapeutics (ARQT), Janux Therapeutics (JANX), Travere Therapeutics (TVTX), Agios Pharmaceuticals (AGIO), Tarsus Pharmaceuticals (TARS), Apogee Therapeutics (APGE), Vera Therapeutics (VERA), Disc Medicine (IRON), and Schrödinger (SDGR). These companies are all part of the "pharmaceutical products" industry. Opthea vs. Harmony Biosciences Arcutis Biotherapeutics Janux Therapeutics Travere Therapeutics Agios Pharmaceuticals Tarsus Pharmaceuticals Apogee Therapeutics Vera Therapeutics Disc Medicine Schrödinger Opthea (NASDAQ:OPT) and Harmony Biosciences (NASDAQ:HRMY) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their analyst recommendations, media sentiment, earnings, institutional ownership, dividends, profitability, community ranking, risk and valuation. Which has more volatility & risk, OPT or HRMY? Opthea has a beta of 1.12, meaning that its share price is 12% more volatile than the S&P 500. Comparatively, Harmony Biosciences has a beta of 0.82, meaning that its share price is 18% less volatile than the S&P 500. Does the MarketBeat Community believe in OPT or HRMY? Harmony Biosciences received 45 more outperform votes than Opthea when rated by MarketBeat users. Likewise, 70.33% of users gave Harmony Biosciences an outperform vote while only 48.72% of users gave Opthea an outperform vote. CompanyUnderperformOutperformOptheaOutperform Votes1948.72% Underperform Votes2051.28% Harmony BiosciencesOutperform Votes6470.33% Underperform Votes2729.67% Is OPT or HRMY more profitable? Harmony Biosciences has a net margin of 17.98% compared to Opthea's net margin of 0.00%. Harmony Biosciences' return on equity of 23.16% beat Opthea's return on equity.Company Net Margins Return on Equity Return on Assets OptheaN/A N/A N/A Harmony Biosciences 17.98%23.16%14.24% Do institutionals and insiders hold more shares of OPT or HRMY? 56.0% of Opthea shares are held by institutional investors. Comparatively, 86.2% of Harmony Biosciences shares are held by institutional investors. 3.2% of Opthea shares are held by company insiders. Comparatively, 30.8% of Harmony Biosciences shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth. Does the media favor OPT or HRMY? In the previous week, Opthea had 29 more articles in the media than Harmony Biosciences. MarketBeat recorded 43 mentions for Opthea and 14 mentions for Harmony Biosciences. Harmony Biosciences' average media sentiment score of 0.91 beat Opthea's score of -0.38 indicating that Harmony Biosciences is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Opthea 2 Very Positive mention(s) 2 Positive mention(s) 11 Neutral mention(s) 10 Negative mention(s) 5 Very Negative mention(s) Neutral Harmony Biosciences 9 Very Positive mention(s) 1 Positive mention(s) 3 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Do analysts recommend OPT or HRMY? Opthea currently has a consensus price target of $1.33, indicating a potential downside of 60.90%. Harmony Biosciences has a consensus price target of $53.33, indicating a potential upside of 60.69%. Given Harmony Biosciences' stronger consensus rating and higher possible upside, analysts clearly believe Harmony Biosciences is more favorable than Opthea.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Opthea 1 Sell rating(s) 4 Hold rating(s) 0 Buy rating(s) 1 Strong Buy rating(s) 2.17Harmony Biosciences 0 Sell rating(s) 0 Hold rating(s) 9 Buy rating(s) 0 Strong Buy rating(s) 3.00 Which has better valuation & earnings, OPT or HRMY? Harmony Biosciences has higher revenue and earnings than Opthea. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioOpthea$87.67K5,986.77-$220.24MN/AN/AHarmony Biosciences$714.73M2.66$128.85M$2.5113.22 SummaryHarmony Biosciences beats Opthea on 13 of the 17 factors compared between the two stocks. Remove Ads Get Opthea News Delivered to You Automatically Sign up to receive the latest news and ratings for OPT and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart OPT vs. The Competition Export to ExcelMetricOptheaBiological Products IndustryMedical SectorNASDAQ ExchangeMarket Cap$524.84M$3.03B$5.63B$7.84BDividend YieldN/A1.54%4.59%4.01%P/E RatioN/A28.9323.3518.67Price / Sales5,986.77429.55387.8490.66Price / CashN/A168.6838.1734.64Price / Book-6.093.926.894.23Net Income-$220.24M-$71.95M$3.20B$247.15M7 Day PerformanceN/A-5.55%-2.99%-2.18%1 Month Performance-23.88%-11.96%1.63%-5.68%1 Year Performance-17.03%-27.81%9.45%-0.74% Opthea Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)OPTOpthea0.6943 of 5 stars$3.41flat$1.33-60.9%-17.0%$524.84M$87,666.000.008Analyst DowngradeShort Interest ↑Analyst RevisionNews CoverageGap UpHRMYHarmony Biosciences4.4468 of 5 stars$34.32+4.9%$53.11+54.8%-1.2%$1.97B$714.73M16.27200ARQTArcutis Biotherapeutics2.6711 of 5 stars$16.42+12.3%$18.80+14.5%+58.7%$1.95B$196.54M-9.17150Short Interest ↓Positive NewsHigh Trading VolumeJANXJanux Therapeutics2.6185 of 5 stars$31.51+2.7%$92.44+193.4%-22.7%$1.86B$10.59M-26.9330Positive NewsTVTXTravere Therapeutics2.7671 of 5 stars$20.87+5.8%$30.62+46.7%+155.3%$1.85B$233.18M-5.09460News CoveragePositive NewsGap UpAGIOAgios Pharmaceuticals4.3328 of 5 stars$31.99+3.4%$56.57+76.8%+3.6%$1.83B$36.50M2.82390Short Interest ↓Positive NewsTARSTarsus Pharmaceuticals1.8596 of 5 stars$47.49-1.2%$63.67+34.1%+42.3%$1.82B$182.95M-12.4650Insider TradeAPGEApogee Therapeutics2.3846 of 5 stars$40.35+1.0%$92.17+128.4%-40.2%$1.82BN/A-16.6791Positive NewsVERAVera Therapeutics3.0988 of 5 stars$28.07+0.3%$64.67+130.4%-38.2%$1.79BN/A-10.7540Positive NewsIRONDisc Medicine3.1531 of 5 stars$51.27+0.5%$89.10+73.8%-15.9%$1.77BN/A-12.8830Insider TradePositive NewsSDGRSchrödinger2.4344 of 5 stars$23.73+3.6%$32.29+36.1%-26.1%$1.73B$207.54M-10.14790 Remove Ads Related Companies and Tools Related Companies HRMY Alternatives ARQT Alternatives JANX Alternatives TVTX Alternatives AGIO Alternatives TARS Alternatives APGE Alternatives VERA Alternatives IRON Alternatives SDGR Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:OPT) was last updated on 3/29/2025 by MarketBeat.com Staff From Our PartnersA brutally honest economic warning for 2025 (see proof)New York Times best-selling financial author and world-renowned economist Addison Wiggin (a man who’s worked s...Banyan Hill Publishing | Sponsored$2 Trillion Disappears Because of Fed's Secretive New Move$2 trillion has disappeared from the US government's books. 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